JP7420720B2 - ＦｃＲｎ抗体およびその使用方法 - Google Patents

ＦｃＲｎ抗体およびその使用方法 Download PDF

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JP7420720B2
JP7420720B2 JP2020532551A JP2020532551A JP7420720B2 JP 7420720 B2 JP7420720 B2 JP 7420720B2 JP 2020532551 A JP2020532551 A JP 2020532551A JP 2020532551 A JP2020532551 A JP 2020532551A JP 7420720 B2 JP7420720 B2 JP 7420720B2
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sequence
antibody
cdr
seq
fcrn
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JP2021506786A (ja
JP2021506786A5 (enExample
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レオナ イー． リング
ダレル ニックス
ニコラス エー． チルフォン
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モメンタ ファーマシューティカルズ インコーポレイテッド
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/283—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against Fc-receptors, e.g. CD16, CD32, CD64
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/51—Complete heavy chain or Fd fragment, i.e. VH + CH1
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/515—Complete light chain, i.e. VL + CL
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565—Complementarity determining region [CDR]

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Genetics & Genomics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Microbiology (AREA)
  • Endocrinology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
JP2020532551A 2017-12-13 2018-12-13 ＦｃＲｎ抗体およびその使用方法 Active JP7420720B2 (ja)

Priority Applications (2)

Application Number Priority Date Filing Date Title
JP2023177190A JP7690538B2 (ja) 2017-12-13 2023-10-13 ＦｃＲｎ抗体およびその使用方法
JP2025089576A JP2025143252A (ja) 2017-12-13 2025-05-29 ＦｃＲｎ抗体およびその使用方法

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201762598402P 2017-12-13 2017-12-13
US62/598,402 2017-12-13
US201862701354P 2018-07-20 2018-07-20
US62/701,354 2018-07-20
PCT/US2018/065568 WO2019118791A1 (en) 2017-12-13 2018-12-13 Fcrn antibodies and methods of use thereof

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JP2023177190A Division JP7690538B2 (ja) 2017-12-13 2023-10-13 ＦｃＲｎ抗体およびその使用方法

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JP2021506786A JP2021506786A (ja) 2021-02-22
JP2021506786A5 JP2021506786A5 (enExample) 2021-05-13
JP7420720B2 true JP7420720B2 (ja) 2024-01-23

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JP2023177190A Active JP7690538B2 (ja) 2017-12-13 2023-10-13 ＦｃＲｎ抗体およびその使用方法
JP2025089576A Pending JP2025143252A (ja) 2017-12-13 2025-05-29 ＦｃＲｎ抗体およびその使用方法

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JP2025089576A Pending JP2025143252A (ja) 2017-12-13 2025-05-29 ＦｃＲｎ抗体およびその使用方法

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US (2) US11773168B2 (enExample)
EP (1) EP3723802A1 (enExample)
JP (3) JP7420720B2 (enExample)
CN (1) CN111712259A (enExample)
AU (1) AU2018386193B2 (enExample)
BR (1) BR112020011310A2 (enExample)
CA (1) CA3085751A1 (enExample)
IL (1) IL275070A (enExample)
SG (1) SG11202005021PA (enExample)
WO (1) WO2019118791A1 (enExample)

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JP2024016042A (ja) * 2017-12-13 2024-02-06 モメンタ ファーマシューティカルズ インコーポレイテッド ＦｃＲｎ抗体およびその使用方法

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CN118638229A (zh) 2015-01-30 2024-09-13 动量制药公司 Fcrn抗体及其使用方法
JP7422659B2 (ja) 2017-12-08 2024-01-26 アルジェニクス ビーブイ 全身型重症筋無力症治療のためのＦｃＲｎアンタゴニストの使用
MX2020013195A (es) 2018-06-08 2021-02-26 Argenx Bvba Composiciones y metodos para el tratamiento de la trombocitopenia inmunitaria.
CA3148826A1 (en) * 2019-08-01 2021-02-04 Janssen Biotech, Inc. Fcrn antibodies and methods of use thereof
FI4087875T3 (fi) 2020-01-08 2024-10-25 argenx BV Vastasyntyneen ihmisen Fc-reseptorin (FcRn) antagonisteja pemfigus-häiriöiden hoitoon
US20230220069A1 (en) * 2020-06-17 2023-07-13 The Trustees Of The University Of Pennsylvania Compositions and methods for treatment of gene therapy patients
EP4240417A4 (en) * 2020-11-06 2024-10-02 Momenta Pharmaceuticals, Inc. ANTI-FCRN ANTIBODIES AND METHODS OF USE THEREOF
CN116234827A (zh) * 2021-09-03 2023-06-06 舒泰神（北京）生物制药股份有限公司 特异性识别FcRn的抗体及其应用
CN114129730A (zh) * 2021-09-16 2022-03-04 宁夏大学 FcRn抑制剂在制备降低炎症反应和/或防治结核病的试剂或药物中的应用
WO2023135321A1 (en) * 2022-01-17 2023-07-20 argenx BV Methods for treating patients with an autoantibody-mediated disease
WO2023242372A1 (en) 2022-06-15 2023-12-21 argenx BV Fcrn/hsa binding molecules and methods of use
TW202517676A (zh) 2023-07-05 2025-05-01 比利時商艾伯霖克斯公司 用於治療ＩｇＧ相關疾病及病症之改良ＦｃＲｎ拮抗劑
TW202527982A (zh) 2023-09-11 2025-07-16 美商默門塔醫藥公司 Fcrn抗體之醫藥組成物
WO2025186787A1 (en) * 2024-03-08 2025-09-12 Momenta Pharmaceuticals, Inc. Compositions and methods for treating fetal and neonatal alloimmune thrombocytopenia

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JP2011523351A (ja) 2008-04-25 2011-08-11 ダイアックス、コープ ＦｃＲｎに対する抗体及びその使用
JP7094941B2 (ja) 2016-07-29 2022-07-04 モメンタ ファーマシューティカルズ インコーポレイテッド Ｆｃｒｎ抗体及びその使用方法

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JP7422659B2 (ja) 2017-12-08 2024-01-26 アルジェニクス ビーブイ 全身型重症筋無力症治療のためのＦｃＲｎアンタゴニストの使用
JP7420720B2 (ja) 2017-12-13 2024-01-23 モメンタ ファーマシューティカルズ インコーポレイテッド ＦｃＲｎ抗体およびその使用方法
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JP7094941B2 (ja) 2016-07-29 2022-07-04 モメンタ ファーマシューティカルズ インコーポレイテッド Ｆｃｒｎ抗体及びその使用方法

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2024016042A (ja) * 2017-12-13 2024-02-06 モメンタ ファーマシューティカルズ インコーポレイテッド ＦｃＲｎ抗体およびその使用方法
JP7690538B2 (ja) 2017-12-13 2025-06-10 モメンタ ファーマシューティカルズ インコーポレイテッド ＦｃＲｎ抗体およびその使用方法

Also Published As

Publication number Publication date
IL275070A (en) 2020-07-30
WO2019118791A1 (en) 2019-06-20
US20240158509A1 (en) 2024-05-16
AU2018386193A8 (en) 2020-07-02
JP2025143252A (ja) 2025-10-01
JP7690538B2 (ja) 2025-06-10
KR20200098604A (ko) 2020-08-20
JP2021506786A (ja) 2021-02-22
US20220064290A1 (en) 2022-03-03
CN111712259A (zh) 2020-09-25
JP2024016042A (ja) 2024-02-06
EP3723802A1 (en) 2020-10-21
SG11202005021PA (en) 2020-07-29
US11773168B2 (en) 2023-10-03
BR112020011310A2 (pt) 2020-11-17
CA3085751A1 (en) 2019-06-20
AU2018386193B2 (en) 2025-04-24
AU2018386193A1 (en) 2020-06-25

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