JP7398806B2 - 認知障害の診断用のノンコーディングＲＮＡ（ｎｃＲＮＡ） - Google Patents

認知障害の診断用のノンコーディングＲＮＡ（ｎｃＲＮＡ） Download PDF

Info

Publication number
JP7398806B2
JP7398806B2 JP2020514246A JP2020514246A JP7398806B2 JP 7398806 B2 JP7398806 B2 JP 7398806B2 JP 2020514246 A JP2020514246 A JP 2020514246A JP 2020514246 A JP2020514246 A JP 2020514246A JP 7398806 B2 JP7398806 B2 JP 7398806B2
Authority
JP
Japan
Prior art keywords
mir
lnc
mirna
expression
mirnas
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
JP2020514246A
Other languages
English (en)
Japanese (ja)
Other versions
JP2020536503A (ja
JP2020536503A5 (https=
Inventor
フセイン・フィラ
サリハ・ムサウイ
エリック・ショルダン
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Amoneta Diagnostics SAS
Original Assignee
Amoneta Diagnostics SAS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Amoneta Diagnostics SAS filed Critical Amoneta Diagnostics SAS
Publication of JP2020536503A publication Critical patent/JP2020536503A/ja
Publication of JP2020536503A5 publication Critical patent/JP2020536503A5/ja
Application granted granted Critical
Publication of JP7398806B2 publication Critical patent/JP7398806B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/178—Oligonucleotides characterized by their use miRNA, siRNA or ncRNA

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Pathology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2020514246A 2017-09-05 2018-09-05 認知障害の診断用のノンコーディングＲＮＡ（ｎｃＲＮＡ） Active JP7398806B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201762554427P 2017-09-05 2017-09-05
US62/554,427 2017-09-05
PCT/EP2018/073905 WO2019048500A1 (en) 2017-09-05 2018-09-05 NON-CODING RNA (RNANC) FOR THE DIAGNOSIS OF COGNITIVE DISORDERS

Publications (3)

Publication Number Publication Date
JP2020536503A JP2020536503A (ja) 2020-12-17
JP2020536503A5 JP2020536503A5 (https=) 2021-10-21
JP7398806B2 true JP7398806B2 (ja) 2023-12-15

Family

ID=63517886

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2020514246A Active JP7398806B2 (ja) 2017-09-05 2018-09-05 認知障害の診断用のノンコーディングＲＮＡ（ｎｃＲＮＡ）

Country Status (5)

Country Link
US (1) US11718879B2 (https=)
EP (1) EP3679157B1 (https=)
JP (1) JP7398806B2 (https=)
CN (1) CN111373052A (https=)
WO (1) WO2019048500A1 (https=)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP4498086A3 (en) * 2018-02-13 2025-04-02 Toray Industries, Inc. Kit or device and method for detecting dementia
WO2021201092A1 (ja) 2020-03-31 2021-10-07 東レ株式会社 海馬萎縮を検出するためのキット又はデバイス及び方法
KR102555878B1 (ko) * 2020-04-23 2023-07-17 주식회사 바이오오케스트라 하향조절된 mirna의 진단 및 치료를 위한 용도
KR102691806B1 (ko) * 2020-04-23 2024-08-06 주식회사 바이오오케스트라 상향조절된 mirna의 진단 및 치료를 위한 용도
CN113667737A (zh) * 2020-07-31 2021-11-19 上海市精神卫生中心（上海市心理咨询培训中心） Mci诊断标志物、mci诊断试剂盒及相应的检测方法
CN112779331B (zh) * 2021-02-05 2022-04-01 浙江萧山医院 一种血管痴呆血清外泌体microRNAs标志物及其应用
CN113234812B (zh) * 2021-06-09 2023-11-03 科德角国际生物医学科技(北京)有限公司 一种用于诊断阿尔茨海默病的诊断试剂
CN113373230B (zh) * 2021-06-18 2022-07-29 福建医科大学附属第一医院 检测生物标志物的试剂在诊断胃癌中的应用
JP2023004314A (ja) * 2021-06-25 2023-01-17 株式会社堀場製作所 心理的ストレスの検出方法及び検出用キット
JP7840033B2 (ja) * 2021-11-02 2026-04-03 学校法人日本医科大学 オキサリプラチン誘発性末梢神経障害バイオマーカー
WO2025011736A1 (en) 2023-07-07 2025-01-16 Genxpro Gmbh A METHOD FOR AN IN VITRO DIAGNOSIS, PROGNOSIS, STAGING AND/OR TREATMENT MONITORING OF A NEURODEGENERATIVE DISEASE, NEUROLOGICAL DISEASE OR AMYLOID β-RELATED DISEASE
CN119020481B (zh) * 2024-08-29 2026-01-30 河络新图生物科技(上海)有限公司 检测xcl2基因表达的物质在制备检测帕金森病产品中的应用

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2014075911A1 (en) 2012-11-16 2014-05-22 Siemens Aktiengesellschaft Diagnostic mirna markers for alzheimer
WO2015179909A1 (en) 2014-05-26 2015-12-03 The University Of Melbourne Mirna biomarkers of alzheimer's disease

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6407132B1 (en) 1997-07-25 2002-06-18 James Black Foundation Limited Substituted imidazole derivatives and their use as histamine H3 receptor ligands
AU2005206389A1 (en) 2004-01-27 2005-08-04 Compugen Ltd. Methods of identifying putative gene products by interspecies sequence comparison and biomolecular sequences uncovered thereby
FR2882056B1 (fr) 2005-02-15 2007-06-01 Centre Nat Rech Scient Dipyrromethenes-bore borocarbones insatures
WO2013024469A1 (en) 2011-08-16 2013-02-21 Rosetta Genomics Ltd. Methods and compositions for diagnosis of alzheimer's desease
US9377472B2 (en) 2012-04-30 2016-06-28 Amoneta Diagnostics Biological complex specific for Alzheimer's disease detection in vitro and use thereof
US20140272993A1 (en) * 2013-03-15 2014-09-18 The Translational Genomics Research Institute Method of sequencing a full microrna profile from cerebrospinal fluid
WO2015031958A1 (en) * 2013-09-06 2015-03-12 Garvan Institute Of Medical Research Regulatory molecules
CN105950705B (zh) * 2015-04-08 2019-10-22 中国人民解放军第二军医大学 一组microRNAs在制备阿尔兹海默氏症诊断试剂或诊断试剂盒中的应用
EP3184646B1 (de) * 2015-12-22 2019-04-17 Siemens Aktiengesellschaft Spezifische signaturen in alzheimer durch multizentrische mirna-profile
WO2020049135A1 (en) 2018-09-05 2020-03-12 Amoneta Diagnostics Sas Long non-coding rnas (lncrnas) for the diagnosis and therapeutics of brain disorders, in particular cognitive disorders

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2014075911A1 (en) 2012-11-16 2014-05-22 Siemens Aktiengesellschaft Diagnostic mirna markers for alzheimer
WO2015179909A1 (en) 2014-05-26 2015-12-03 The University Of Melbourne Mirna biomarkers of alzheimer's disease

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
COGSWELL, J. P. et al.，Identification of miRNA changes in Alzheimer's disease brain and CSF yields putative biomarkers and insights into disease pathways.，Journal of Alzheimer's disease，2008年，Vol. 14，P. 27-41
GUI, Y. et al.，Altered microRNA profiles in cerebrospinal fluid exosome in Parkinson disease and Alzheimer disease.，Oncotarget，2015年，Vol. 6, No. 35，P. 37043-37053

Also Published As

Publication number Publication date
CN111373052A (zh) 2020-07-03
JP2020536503A (ja) 2020-12-17
EP3679157A1 (en) 2020-07-15
EP3679157B1 (en) 2024-12-18
US11718879B2 (en) 2023-08-08
WO2019048500A1 (en) 2019-03-14
EP3679157C0 (en) 2024-12-18
US20210071252A1 (en) 2021-03-11

Similar Documents

Publication Publication Date Title
JP7398806B2 (ja) 認知障害の診断用のノンコーディングＲＮＡ（ｎｃＲＮＡ）
US12344895B2 (en) Long non-coding RNAS (LNCRNAS) for the diagnosis and therapeutics of brain disorders, in particular cognitive disorders
Fransquet et al. Micro RNA as a potential blood-based epigenetic biomarker for Alzheimer's disease
CN103620057B (zh) 使用来自体液的miRNA来早期检测和监控轻度认知障碍(MCI)和阿尔茨海默病(AD)的方法
EP3891295B1 (en) Methods of diagnosing a disease state
TWI580788B (zh) 用於檢測川崎病的方法及套組
ES2993025T3 (en) Methods of using mirnas from bodily fluids for detection and differentiation of neurodegenerative diseases
CN104981548A (zh) 用于阿尔茨海默氏病的诊断性miRNA标志物
Song et al. Microarray microRNA profiling of urinary exosomes in a 5XFAD mouse model of Alzheimer’s disease
TW201944070A (zh) 用於檢測狼瘡性腎炎或評估狼瘡性腎炎風險的方法及其應用
AU2021313706A1 (en) Biomarkers for cognitive conditions
KR102555878B1 (ko) 하향조절된 mirna의 진단 및 치료를 위한 용도
JP7394441B2 (ja) 脳腫瘍を検査する方法
CN116218986A (zh) 一种诊断是否患有阿尔茨海默病的试剂盒及其用途
CN108531571B (zh) 用于检测注意力缺陷/过动症的方法和试剂盒
CN113151450A (zh) 一种用于散发性肌萎缩性侧索硬化症和帕金森病早期诊断的生物标志物及其应用
EP4431616A1 (en) Diagnosis marker detection method and diagnostic kit
Kerrebijn Elucidating cell types associated with case-control differences in cortical thickness in neuropsychiatric disorders
Shireby Regulatory genomic consequences of polygenic risk burden for Alzheimer’s disease
US20200308647A1 (en) Mirnas as biomarkers for alzheimer's disease
CN116769899A (zh) 血浆外泌体中has-miR-196在吗啡/海洛因依赖临床诊断和评估中的应用
HK1225759B (zh) 用於检测川崎病的方法及试剂盒

Legal Events

Date Code Title Description
A711 Notification of change in applicant

Free format text: JAPANESE INTERMEDIATE CODE: A711

Effective date: 20210805

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20210902

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20210902

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A821

Effective date: 20210805

A977 Report on retrieval

Free format text: JAPANESE INTERMEDIATE CODE: A971007

Effective date: 20220714

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20220802

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20221101

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20230110

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20230410

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20230620

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20230920

TRDD Decision of grant or rejection written
A01 Written decision to grant a patent or to grant a registration (utility model)

Free format text: JAPANESE INTERMEDIATE CODE: A01

Effective date: 20231031

A61 First payment of annual fees (during grant procedure)

Free format text: JAPANESE INTERMEDIATE CODE: A61

Effective date: 20231128

R150 Certificate of patent or registration of utility model

Ref document number: 7398806

Country of ref document: JP

Free format text: JAPANESE INTERMEDIATE CODE: R150