CN111373052A - 非编码RNA(ncRNA)用于认知障碍的诊断 - Google Patents
非编码RNA(ncRNA)用于认知障碍的诊断 Download PDFInfo
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- CN111373052A CN111373052A CN201880068913.3A CN201880068913A CN111373052A CN 111373052 A CN111373052 A CN 111373052A CN 201880068913 A CN201880068913 A CN 201880068913A CN 111373052 A CN111373052 A CN 111373052A
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/178—Oligonucleotides characterized by their use miRNA, siRNA or ncRNA
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- Proteomics, Peptides & Aminoacids (AREA)
- Health & Medical Sciences (AREA)
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762554427P | 2017-09-05 | 2017-09-05 | |
| US62/554,427 | 2017-09-05 | ||
| PCT/EP2018/073905 WO2019048500A1 (en) | 2017-09-05 | 2018-09-05 | NON-CODING RNA (RNANC) FOR THE DIAGNOSIS OF COGNITIVE DISORDERS |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN111373052A true CN111373052A (zh) | 2020-07-03 |
Family
ID=63517886
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201880068913.3A Pending CN111373052A (zh) | 2017-09-05 | 2018-09-05 | 非编码RNA(ncRNA)用于认知障碍的诊断 |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US11718879B2 (https=) |
| EP (1) | EP3679157B1 (https=) |
| JP (1) | JP7398806B2 (https=) |
| CN (1) | CN111373052A (https=) |
| WO (1) | WO2019048500A1 (https=) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111690739A (zh) * | 2020-07-31 | 2020-09-22 | 上海市精神卫生中心(上海市心理咨询培训中心) | Mci诊断标志物、mci诊断试剂盒及相应的检测方法 |
| CN112779331A (zh) * | 2021-02-05 | 2021-05-11 | 浙江萧山医院 | 一种血管痴呆血清外泌体microRNAs标志物及其应用 |
| CN113234812A (zh) * | 2021-06-09 | 2021-08-10 | 济南帕斯维德生物科技有限公司 | 一种用于诊断阿尔茨海默病的诊断试剂 |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP4498086A3 (en) * | 2018-02-13 | 2025-04-02 | Toray Industries, Inc. | Kit or device and method for detecting dementia |
| WO2021201092A1 (ja) | 2020-03-31 | 2021-10-07 | 東レ株式会社 | 海馬萎縮を検出するためのキット又はデバイス及び方法 |
| KR102555878B1 (ko) * | 2020-04-23 | 2023-07-17 | 주식회사 바이오오케스트라 | 하향조절된 mirna의 진단 및 치료를 위한 용도 |
| KR102691806B1 (ko) * | 2020-04-23 | 2024-08-06 | 주식회사 바이오오케스트라 | 상향조절된 mirna의 진단 및 치료를 위한 용도 |
| CN113373230B (zh) * | 2021-06-18 | 2022-07-29 | 福建医科大学附属第一医院 | 检测生物标志物的试剂在诊断胃癌中的应用 |
| JP2023004314A (ja) * | 2021-06-25 | 2023-01-17 | 株式会社堀場製作所 | 心理的ストレスの検出方法及び検出用キット |
| JP7840033B2 (ja) * | 2021-11-02 | 2026-04-03 | 学校法人日本医科大学 | オキサリプラチン誘発性末梢神経障害バイオマーカー |
| WO2025011736A1 (en) | 2023-07-07 | 2025-01-16 | Genxpro Gmbh | A METHOD FOR AN IN VITRO DIAGNOSIS, PROGNOSIS, STAGING AND/OR TREATMENT MONITORING OF A NEURODEGENERATIVE DISEASE, NEUROLOGICAL DISEASE OR AMYLOID β-RELATED DISEASE |
| CN119020481B (zh) * | 2024-08-29 | 2026-01-30 | 河络新图生物科技(上海)有限公司 | 检测xcl2基因表达的物质在制备检测帕金森病产品中的应用 |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2013024469A1 (en) * | 2011-08-16 | 2013-02-21 | Rosetta Genomics Ltd. | Methods and compositions for diagnosis of alzheimer's desease |
| WO2014075911A1 (en) * | 2012-11-16 | 2014-05-22 | Siemens Aktiengesellschaft | Diagnostic mirna markers for alzheimer |
| US20140272993A1 (en) * | 2013-03-15 | 2014-09-18 | The Translational Genomics Research Institute | Method of sequencing a full microrna profile from cerebrospinal fluid |
| WO2015031958A1 (en) * | 2013-09-06 | 2015-03-12 | Garvan Institute Of Medical Research | Regulatory molecules |
| CN105950705A (zh) * | 2015-04-08 | 2016-09-21 | 中国人民解放军第二军医大学 | 一组microRNAs在制备阿尔兹海默氏症诊断试剂或诊断试剂盒中的应用 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6407132B1 (en) | 1997-07-25 | 2002-06-18 | James Black Foundation Limited | Substituted imidazole derivatives and their use as histamine H3 receptor ligands |
| AU2005206389A1 (en) | 2004-01-27 | 2005-08-04 | Compugen Ltd. | Methods of identifying putative gene products by interspecies sequence comparison and biomolecular sequences uncovered thereby |
| FR2882056B1 (fr) | 2005-02-15 | 2007-06-01 | Centre Nat Rech Scient | Dipyrromethenes-bore borocarbones insatures |
| US9377472B2 (en) | 2012-04-30 | 2016-06-28 | Amoneta Diagnostics | Biological complex specific for Alzheimer's disease detection in vitro and use thereof |
| WO2015179909A1 (en) * | 2014-05-26 | 2015-12-03 | The University Of Melbourne | Mirna biomarkers of alzheimer's disease |
| EP3184646B1 (de) * | 2015-12-22 | 2019-04-17 | Siemens Aktiengesellschaft | Spezifische signaturen in alzheimer durch multizentrische mirna-profile |
| WO2020049135A1 (en) | 2018-09-05 | 2020-03-12 | Amoneta Diagnostics Sas | Long non-coding rnas (lncrnas) for the diagnosis and therapeutics of brain disorders, in particular cognitive disorders |
-
2018
- 2018-09-05 EP EP18765623.6A patent/EP3679157B1/en active Active
- 2018-09-05 CN CN201880068913.3A patent/CN111373052A/zh active Pending
- 2018-09-05 JP JP2020514246A patent/JP7398806B2/ja active Active
- 2018-09-05 US US16/644,812 patent/US11718879B2/en active Active
- 2018-09-05 WO PCT/EP2018/073905 patent/WO2019048500A1/en not_active Ceased
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2013024469A1 (en) * | 2011-08-16 | 2013-02-21 | Rosetta Genomics Ltd. | Methods and compositions for diagnosis of alzheimer's desease |
| WO2014075911A1 (en) * | 2012-11-16 | 2014-05-22 | Siemens Aktiengesellschaft | Diagnostic mirna markers for alzheimer |
| US20140272993A1 (en) * | 2013-03-15 | 2014-09-18 | The Translational Genomics Research Institute | Method of sequencing a full microrna profile from cerebrospinal fluid |
| WO2015031958A1 (en) * | 2013-09-06 | 2015-03-12 | Garvan Institute Of Medical Research | Regulatory molecules |
| CN105950705A (zh) * | 2015-04-08 | 2016-09-21 | 中国人民解放军第二军医大学 | 一组microRNAs在制备阿尔兹海默氏症诊断试剂或诊断试剂盒中的应用 |
Non-Patent Citations (4)
| Title |
|---|
| JOHN P COGSWELL等: "Identification of miRNA Changes in Alzheimer\'s Disease Brain and CSF Yields Putative Biomarkers and Insights into Disease Pathways", J ALZHEIMERS DIS, vol. 14, no. 1, 31 May 2008 (2008-05-31), pages 27 - 41 * |
| JUN-ICHI SATOH等: "MicroRNA-Seq Data Analysis Pipeline to Identify Blood Biomarkers for Alzheimer\'s Disease from Public Data", BIOMARK INSIGHTS, vol. 10, 15 April 2015 (2015-04-15), pages 21 - 31 * |
| XIAOLIN ZHOU等: "Identification of Alzheimer\'s disease-associated long noncoding RNAs", NEUROBIOL AGING, vol. 36, no. 11, 30 November 2015 (2015-11-30), pages 2925 - 2931 * |
| 刘辰庚等: "microRNA-135a在阿尔茨海默病患者中的检测价值", 中国老年学杂志, vol. 36, no. 1, 31 January 2016 (2016-01-31), pages 152 - 153 * |
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111690739A (zh) * | 2020-07-31 | 2020-09-22 | 上海市精神卫生中心(上海市心理咨询培训中心) | Mci诊断标志物、mci诊断试剂盒及相应的检测方法 |
| WO2022022060A1 (zh) * | 2020-07-31 | 2022-02-03 | 上海市精神卫生中心(上海市心理咨询培训中心) | Mci诊断标志物、mci诊断试剂盒及相应的检测方法 |
| CN111690739B (zh) * | 2020-07-31 | 2022-09-16 | 上海市精神卫生中心(上海市心理咨询培训中心) | Mci诊断标志物、mci诊断试剂盒及相应的检测方法 |
| CN112779331A (zh) * | 2021-02-05 | 2021-05-11 | 浙江萧山医院 | 一种血管痴呆血清外泌体microRNAs标志物及其应用 |
| CN113234812A (zh) * | 2021-06-09 | 2021-08-10 | 济南帕斯维德生物科技有限公司 | 一种用于诊断阿尔茨海默病的诊断试剂 |
| CN113234812B (zh) * | 2021-06-09 | 2023-11-03 | 科德角国际生物医学科技(北京)有限公司 | 一种用于诊断阿尔茨海默病的诊断试剂 |
Also Published As
| Publication number | Publication date |
|---|---|
| JP2020536503A (ja) | 2020-12-17 |
| EP3679157A1 (en) | 2020-07-15 |
| EP3679157B1 (en) | 2024-12-18 |
| US11718879B2 (en) | 2023-08-08 |
| JP7398806B2 (ja) | 2023-12-15 |
| WO2019048500A1 (en) | 2019-03-14 |
| EP3679157C0 (en) | 2024-12-18 |
| US20210071252A1 (en) | 2021-03-11 |
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