JP7389020B2 - 幹細胞からインビトロで誘導されたnkx6.1およびc-ペプチド共発現細胞の濃縮 - Google Patents

幹細胞からインビトロで誘導されたnkx6.1およびc-ペプチド共発現細胞の濃縮 Download PDF

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JP7389020B2
JP7389020B2 JP2020512652A JP2020512652A JP7389020B2 JP 7389020 B2 JP7389020 B2 JP 7389020B2 JP 2020512652 A JP2020512652 A JP 2020512652A JP 2020512652 A JP2020512652 A JP 2020512652A JP 7389020 B2 JP7389020 B2 JP 7389020B2
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JP2020532978A (ja
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キェルケゴール、ジャネッテ、シュリクティング
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Novo Nordisk AS
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    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/37Digestive system
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    • C12N2506/00Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
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JP2020512652A 2017-09-11 2018-09-11 幹細胞からインビトロで誘導されたnkx6.1およびc-ペプチド共発現細胞の濃縮 Active JP7389020B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP17190412 2017-09-11
EP17190412.1 2017-09-11
PCT/EP2018/074390 WO2019048690A1 (en) 2017-09-11 2018-09-11 ENRICHMENT OF CELLS COEXPRESSING NKX6.1 AND PEPTIDE C, IN VITRO DERIVATIVES FROM STEM CELLS

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JP2020532978A JP2020532978A (ja) 2020-11-19
JP7389020B2 true JP7389020B2 (ja) 2023-11-29

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US (1) US20200199540A1 (pt)
EP (1) EP3681992A1 (pt)
JP (1) JP7389020B2 (pt)
KR (1) KR20200051664A (pt)
CN (1) CN111108190B (pt)
AU (1) AU2018330499A1 (pt)
BR (1) BR112020004428A2 (pt)
CA (1) CA3074910A1 (pt)
CO (1) CO2020003122A2 (pt)
IL (1) IL272734A (pt)
MA (1) MA50279A (pt)
MX (1) MX2020002421A (pt)
RU (1) RU2020111055A (pt)
SA (1) SA520411466B1 (pt)
SG (1) SG11202001906PA (pt)
WO (1) WO2019048690A1 (pt)

Families Citing this family (4)

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Publication number Priority date Publication date Assignee Title
US20220177849A1 (en) 2019-04-08 2022-06-09 Novo Nordisk A/S Generation of pancreatic endoderm from stem cell derived definitive endoderm
EP4061929A1 (en) 2019-11-22 2022-09-28 Novo Nordisk A/S Spin-aggregated neural microspheres and the application thereof
WO2023203208A1 (en) 2022-04-21 2023-10-26 Evotec International Gmbh New cell populations and means and methods for their differentiation and preservation
WO2024008810A1 (en) 2022-07-06 2024-01-11 Novo Nordisk A/S Differentiation of stem cells to pancreatic endocrine cells

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2016504037A (ja) 2012-12-31 2016-02-12 ヤンセン バイオテツク,インコーポレーテツド 膵内分泌細胞への分化のためのヒト多能性細胞の懸濁及びクラスタリング
JP2016513972A (ja) 2013-03-14 2016-05-19 ヴィアサイト インコーポレイテッド 多能性幹細胞の膵臓内胚葉細胞(PEC)および内分泌細胞へのinvitro分化
WO2017144695A1 (en) 2016-02-24 2017-08-31 Novo Nordisk A/S Generation of functional beta cells from human pluripotent stem cell-derived endocrine progenitors

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CA2018638C (en) * 1990-06-08 2002-10-01 Wah Jun Tze Banking of pancreatic endocrine cells for transplantation
JP2005512593A (ja) 2001-12-28 2005-05-12 セルアーティス アーベー 多能性のヒト胚盤胞由来幹細胞株の樹立方法
GB2445338A (en) 2005-10-07 2008-07-02 Cellartis Ab A method for obtaining a xeno-free HBS cell line
US7695965B2 (en) * 2006-03-02 2010-04-13 Cythera, Inc. Methods of producing pancreatic hormones
US9080145B2 (en) * 2007-07-01 2015-07-14 Lifescan Corporation Single pluripotent stem cell culture
EP2356227B1 (en) * 2008-11-14 2018-03-28 Viacyte, Inc. Encapsulation of pancreatic cells derived from human pluripotent stem cells
RU2607380C2 (ru) * 2010-03-01 2017-01-10 Янссен Байотек, Инк. Способы очистки клеток, производных от плюрипотентных стволовых клеток
CN108220224A (zh) 2011-06-21 2018-06-29 诺沃—诺迪斯克有限公司 自多潜能干细胞有效诱导定形内胚层
EP2893000B1 (en) 2012-09-03 2019-04-10 Novo Nordisk A/S Generation of pancreatic endoderm from pluripotent stem cells using small molecules
WO2014138671A2 (en) * 2013-03-08 2014-09-12 Viacyte, Inc. Cryopreservation, hibernation and room temperature storage of encapulated pancreatic endoderm cell aggregates
CN105683361B (zh) * 2013-08-30 2021-04-02 诺和诺德股份有限公司 使用小分子从人多能干细胞产生内分泌祖细胞
JP2017112835A (ja) * 2014-04-17 2017-06-29 東京エレクトロン株式会社 多能性幹細胞の凍結保存方法および凍結保存システム
WO2017094001A1 (en) * 2015-11-30 2017-06-08 Kadimastem Ltd Methods for differentiating and purifying pancreatic endocrine cells

Patent Citations (3)

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JP2016504037A (ja) 2012-12-31 2016-02-12 ヤンセン バイオテツク,インコーポレーテツド 膵内分泌細胞への分化のためのヒト多能性細胞の懸濁及びクラスタリング
JP2016513972A (ja) 2013-03-14 2016-05-19 ヴィアサイト インコーポレイテッド 多能性幹細胞の膵臓内胚葉細胞(PEC)および内分泌細胞へのinvitro分化
WO2017144695A1 (en) 2016-02-24 2017-08-31 Novo Nordisk A/S Generation of functional beta cells from human pluripotent stem cell-derived endocrine progenitors

Non-Patent Citations (1)

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Title
Stem Cells Translational Medicine,2015年,Vol.4,pp.1214-1222

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MX2020002421A (es) 2020-07-13
CO2020003122A2 (es) 2020-06-19
US20200199540A1 (en) 2020-06-25
CA3074910A1 (en) 2019-03-14
RU2020111055A (ru) 2021-09-17
CN111108190B (zh) 2024-06-21
EP3681992A1 (en) 2020-07-22
MA50279A (fr) 2020-07-22
WO2019048690A1 (en) 2019-03-14
SA520411466B1 (ar) 2024-03-10
JP2020532978A (ja) 2020-11-19
BR112020004428A2 (pt) 2020-09-08
RU2020111055A3 (pt) 2022-04-22
IL272734A (en) 2020-04-30
CN111108190A (zh) 2020-05-05
SG11202001906PA (en) 2020-04-29
AU2018330499A1 (en) 2020-04-09
KR20200051664A (ko) 2020-05-13

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