MA50279A - Enrichissement de cellules coexprimant nkx6.1 et le peptide c, dérivées in vitro à partir de cellules souches - Google Patents

Enrichissement de cellules coexprimant nkx6.1 et le peptide c, dérivées in vitro à partir de cellules souches

Info

Publication number
MA50279A
MA50279A MA050279A MA50279A MA50279A MA 50279 A MA50279 A MA 50279A MA 050279 A MA050279 A MA 050279A MA 50279 A MA50279 A MA 50279A MA 50279 A MA50279 A MA 50279A
Authority
MA
Morocco
Prior art keywords
cells
enrichment
expressing
peptide
stem cells
Prior art date
Application number
MA050279A
Other languages
English (en)
Inventor
Allé Novo
Original Assignee
Novo Nordisk As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novo Nordisk As filed Critical Novo Nordisk As
Publication of MA50279A publication Critical patent/MA50279A/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0676—Pancreatic cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0676—Pancreatic cells
    • C12N5/0677—Three-dimensional culture, tissue culture or organ culture; Encapsulated cells
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00—Preservation of bodies of humans or animals, or parts thereof
    • A01N1/02—Preservation of living parts
    • A01N1/0278—Physical preservation processes
    • A01N1/0284—Temperature processes, i.e. using a designated change in temperature over time
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/37—Digestive system
    • A61K35/39—Pancreas; Islets of Langerhans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
    • C12N2506/02—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from embryonic cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2509/00—Methods for the dissociation of cells, e.g. specific use of enzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2523/00—Culture process characterised by temperature
MA050279A 2017-09-11 2018-09-11 Enrichissement de cellules coexprimant nkx6.1 et le peptide c, dérivées in vitro à partir de cellules souches MA50279A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP17190412 2017-09-11

Publications (1)

Publication Number Publication Date
MA50279A true MA50279A (fr) 2020-07-22

Family

ID=59846503

Family Applications (1)

Application Number Title Priority Date Filing Date
MA050279A MA50279A (fr) 2017-09-11 2018-09-11 Enrichissement de cellules coexprimant nkx6.1 et le peptide c, dérivées in vitro à partir de cellules souches

Country Status (15)

Country Link
US (1) US20200199540A1 (fr)
EP (1) EP3681992A1 (fr)
JP (1) JP7389020B2 (fr)
KR (1) KR20200051664A (fr)
CN (1) CN111108190A (fr)
AU (1) AU2018330499A1 (fr)
BR (1) BR112020004428A2 (fr)
CA (1) CA3074910A1 (fr)
CO (1) CO2020003122A2 (fr)
IL (1) IL272734A (fr)
MA (1) MA50279A (fr)
MX (1) MX2020002421A (fr)
RU (1) RU2020111055A (fr)
SG (1) SG11202001906PA (fr)
WO (1) WO2019048690A1 (fr)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113728090B (zh) 2019-04-08 2024-04-05 诺和诺德股份有限公司 从干细胞衍生的定形内胚层生成胰腺内胚层
CN114729323A (zh) 2019-11-22 2022-07-08 诺和诺德股份有限公司 旋转聚集的神经微球及其应用
WO2023203208A1 (fr) 2022-04-21 2023-10-26 Evotec International Gmbh Nouvelles populations de cellules et moyens et procédés pour leur différenciation et leur conservation
WO2024008810A1 (fr) 2022-07-06 2024-01-11 Novo Nordisk A/S Différenciation de cellules souches en cellules endocrines pancréatiques

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2018638C (fr) * 1990-06-08 2002-10-01 Wah Jun Tze Mise en banque de cellules endocrines de pancreas pour les transplantations
US20050095703A1 (en) 2001-12-28 2005-05-05 Henrik Semb Method for the establishment of a pluripotent human blastocyst - derived stem cell line
CA2624728A1 (fr) 2005-10-07 2007-04-19 Cellartis Ab Procede pour l'obtention d'une lignee cellulaire hbs exempte de xeno-contaminants
US7695965B2 (en) * 2006-03-02 2010-04-13 Cythera, Inc. Methods of producing pancreatic hormones
US9080145B2 (en) * 2007-07-01 2015-07-14 Lifescan Corporation Single pluripotent stem cell culture
CN105349517B (zh) * 2008-11-14 2021-05-04 维赛特公司 源于人多能干细胞的胰腺细胞的包封
AU2011223900A1 (en) * 2010-03-01 2012-09-13 Janssen Biotech, Inc. Methods for purifying cells derived from pluripotent stem cells
ES2902650T3 (es) 2011-06-21 2022-03-29 Novo Nordisk As Inducción eficiente de endodermo definitivo a partir de células madre pluripotentes
US20150247123A1 (en) 2012-09-03 2015-09-03 Novo Nordisk A/S Generation of pancreatic endoderm from Pluripotent Stem cells using small molecules
JP6529440B2 (ja) * 2012-12-31 2019-06-12 ヤンセン バイオテツク，インコーポレーテツド 膵内分泌細胞への分化のためのヒト多能性細胞の懸濁及びクラスタリング
WO2014138671A2 (fr) * 2013-03-08 2014-09-12 Viacyte, Inc. Cryopréservation, hibernation et stockage à température ambiante d'agrégats de cellules endodermiques pancréatiques encapsulés
US8859286B2 (en) * 2013-03-14 2014-10-14 Viacyte, Inc. In vitro differentiation of pluripotent stem cells to pancreatic endoderm cells (PEC) and endocrine cells
DK3039122T3 (da) * 2013-08-30 2019-09-30 Novo Nordisk As Generering af endokrine progenitorceller fra humane pluripotente stamceller under anvendelse af små molekyler
JP2017112835A (ja) * 2014-04-17 2017-06-29 東京エレクトロン株式会社 多能性幹細胞の凍結保存方法および凍結保存システム
EP3384286B1 (fr) * 2015-11-30 2023-04-19 Kadimastem Ltd. Procédés de différenciation et de purification de cellules endocrines pancréatiques
US11274280B2 (en) * 2016-02-24 2022-03-15 Novo Nordisk A/S Generation of functional beta cells from human pluripotent stem cell-derived endocrine progenitors

Also Published As

Publication number Publication date
JP2020532978A (ja) 2020-11-19
US20200199540A1 (en) 2020-06-25
KR20200051664A (ko) 2020-05-13
CO2020003122A2 (es) 2020-06-19
CN111108190A (zh) 2020-05-05
IL272734A (en) 2020-04-30
BR112020004428A2 (pt) 2020-09-08
RU2020111055A (ru) 2021-09-17
AU2018330499A1 (en) 2020-04-09
WO2019048690A1 (fr) 2019-03-14
MX2020002421A (es) 2020-07-13
EP3681992A1 (fr) 2020-07-22
SG11202001906PA (en) 2020-04-29
CA3074910A1 (fr) 2019-03-14
RU2020111055A3 (fr) 2022-04-22
JP7389020B2 (ja) 2023-11-29

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