JP7358451B2 - 安定な濃厚放射性核種錯体溶液 - Google Patents
安定な濃厚放射性核種錯体溶液 Download PDFInfo
- Publication number
- JP7358451B2 JP7358451B2 JP2021504214A JP2021504214A JP7358451B2 JP 7358451 B2 JP7358451 B2 JP 7358451B2 JP 2021504214 A JP2021504214 A JP 2021504214A JP 2021504214 A JP2021504214 A JP 2021504214A JP 7358451 B2 JP7358451 B2 JP 7358451B2
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- stabilizer
- solution
- concentration
- dota
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
- A61K51/083—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins the peptide being octreotide or a somatostatin-receptor-binding peptide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/12—Carboxylic acids; Salts or anhydrides thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
- A61K51/088—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins conjugates with carriers being peptides, polyamino acids or proteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Optics & Photonics (AREA)
- Physics & Mathematics (AREA)
- Dermatology (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2023085502A JP2023126209A (ja) | 2018-07-25 | 2023-05-24 | 安定な濃厚放射性核種錯体溶液 |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PCT/IB2018/055575 WO2020021310A1 (fr) | 2018-07-25 | 2018-07-25 | Solutions complexes de radionucléides, stables, concentrées |
Related Child Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2023085502A Division JP2023126209A (ja) | 2018-07-25 | 2023-05-24 | 安定な濃厚放射性核種錯体溶液 |
Publications (2)
Publication Number | Publication Date |
---|---|
JP2022500355A JP2022500355A (ja) | 2022-01-04 |
JP7358451B2 true JP7358451B2 (ja) | 2023-10-10 |
Family
ID=63371737
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2021504214A Active JP7358451B2 (ja) | 2018-07-25 | 2018-07-25 | 安定な濃厚放射性核種錯体溶液 |
JP2023085502A Pending JP2023126209A (ja) | 2018-07-25 | 2023-05-24 | 安定な濃厚放射性核種錯体溶液 |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2023085502A Pending JP2023126209A (ja) | 2018-07-25 | 2023-05-24 | 安定な濃厚放射性核種錯体溶液 |
Country Status (3)
Country | Link |
---|---|
JP (2) | JP7358451B2 (fr) |
AR (1) | AR119655A1 (fr) |
WO (1) | WO2020021310A1 (fr) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US11541134B1 (en) | 2021-08-02 | 2023-01-03 | Rayzebio, Inc. | Stabilized compositions of radionuclides and uses thereof |
CN118159303A (zh) * | 2022-02-04 | 2024-06-07 | 先进加速器应用公司 | 用于大规模合成放射性核素络合物的方法 |
CN117159753A (zh) * | 2022-04-20 | 2023-12-05 | 北京先通国际医药科技股份有限公司 | 放射性标记的伊文思蓝衍生物药物的制备方法及用途 |
WO2023202730A2 (fr) * | 2022-04-20 | 2023-10-26 | 北京先通国际医药科技股份有限公司 | Solution aqueuse pharmaceutique dérivée de bleu d'evans radioactif, son procédé de préparation et son utilisation |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2006528644A (ja) | 2003-07-24 | 2006-12-21 | ブラッコ・イメージング・ソシエタ・ペル・アチオニ | 安定な放射性医薬品組成物およびその製法 |
WO2008009444A1 (fr) | 2006-07-19 | 2008-01-24 | Van Dulmen, Adrianus, A. | Utilisation de l'éthanol pour stabiliser une formulation liquide d'un peptide radiomarqué en flacon unique |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR102484725B1 (ko) * | 2016-11-04 | 2023-01-06 | 클라리티 파마슈티컬스 리미티드 | 방사선 요법 및 진단 영상용 제형 |
-
2018
- 2018-07-25 JP JP2021504214A patent/JP7358451B2/ja active Active
- 2018-07-25 WO PCT/IB2018/055575 patent/WO2020021310A1/fr active Application Filing
-
2019
- 2019-07-23 AR ARP190102070A patent/AR119655A1/es unknown
-
2023
- 2023-05-24 JP JP2023085502A patent/JP2023126209A/ja active Pending
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2006528644A (ja) | 2003-07-24 | 2006-12-21 | ブラッコ・イメージング・ソシエタ・ペル・アチオニ | 安定な放射性医薬品組成物およびその製法 |
WO2008009444A1 (fr) | 2006-07-19 | 2008-01-24 | Van Dulmen, Adrianus, A. | Utilisation de l'éthanol pour stabiliser une formulation liquide d'un peptide radiomarqué en flacon unique |
Non-Patent Citations (6)
Title |
---|
Cancer Biotherapy and Radiopharmaceuticals, 2017.11, Vol.32, pp.266-273 |
J. Radioanal. Nucl. Chem., 2014, Vol.302, pp.889-894 |
J. Radioanal. Nucl. Chem., 2017.11, Vol.314, pp.2181-2188, <DOI 10.1007/s10967-017-5595-1> |
Journal of Radioanalytical and Nuclear Chemistry, 2007, Vol.273, No.3, pp.689-694 |
Majalah Polimer Indonesia, Vol.19, No.1, 2016, pp.1-14 |
PRODUCTION and QUALITY CONTROL of 177Lu-DOTATATE [177Lu-DOTA-Tyr3]- OCTREOTATE: CLINICAL APPLICATION [retrieved on 2022/04/20], 2009,<https://inis.iaea.org/collection/NCLCollectionStore/_Public/43/004/43004240.pdf> |
Also Published As
Publication number | Publication date |
---|---|
AR119655A1 (es) | 2022-01-05 |
JP2022500355A (ja) | 2022-01-04 |
WO2020021310A1 (fr) | 2020-01-30 |
JP2023126209A (ja) | 2023-09-07 |
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