JP7356349B2 - 前立腺癌検出 - Google Patents

前立腺癌検出 Download PDF

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Publication number
JP7356349B2
JP7356349B2 JP2019547146A JP2019547146A JP7356349B2 JP 7356349 B2 JP7356349 B2 JP 7356349B2 JP 2019547146 A JP2019547146 A JP 2019547146A JP 2019547146 A JP2019547146 A JP 2019547146A JP 7356349 B2 JP7356349 B2 JP 7356349B2
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methylation
dna
sample
nucleic acid
markers
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Japanese (ja)
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JP2020513795A (ja
Inventor
エー． アールクイスト，デビッド
アール． テイラー，ウィリアム
ビー． キシエル，ジョーン
シー． ヤブ，トレーシー
ダブリュー． マホーニー，ダグラス
エー． ドゥーケク，ブライアン
ティー． ゲットマン，マシュー
ティー． アラーウィ，ハティム
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Mayo Clinic in Florida
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Mayo Clinic in Florida
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Priority to JP2023094124A priority Critical patent/JP7674415B2/ja
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Publication of JP7356349B2 publication Critical patent/JP7356349B2/ja
Priority to JP2025072146A priority patent/JP2025114618A/ja
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6827—Hybridisation assays for detection of mutation or polymorphism
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/154—Methylation markers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/16—Primer sets for multiplex assays

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Immunology (AREA)
  • Analytical Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Hospice & Palliative Care (AREA)
  • Oncology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
JP2019547146A 2017-02-28 2018-02-27 前立腺癌検出 Active JP7356349B2 (ja)

Priority Applications (2)

Application Number Priority Date Filing Date Title
JP2023094124A JP7674415B2 (ja) 2017-02-28 2023-06-07 前立腺癌検出
JP2025072146A JP2025114618A (ja) 2017-02-28 2025-04-24 前立腺癌検出

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201762464800P 2017-02-28 2017-02-28
US62/464,800 2017-02-28
PCT/US2018/019982 WO2018160576A1 (en) 2017-02-28 2018-02-27 Detecting prostate cancer

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2023094124A Division JP7674415B2 (ja) 2017-02-28 2023-06-07 前立腺癌検出

Publications (2)

Publication Number Publication Date
JP2020513795A JP2020513795A (ja) 2020-05-21
JP7356349B2 true JP7356349B2 (ja) 2023-10-04

Family

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Family Applications (3)

Application Number Title Priority Date Filing Date
JP2019547146A Active JP7356349B2 (ja) 2017-02-28 2018-02-27 前立腺癌検出
JP2023094124A Active JP7674415B2 (ja) 2017-02-28 2023-06-07 前立腺癌検出
JP2025072146A Pending JP2025114618A (ja) 2017-02-28 2025-04-24 前立腺癌検出

Family Applications After (2)

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JP2023094124A Active JP7674415B2 (ja) 2017-02-28 2023-06-07 前立腺癌検出
JP2025072146A Pending JP2025114618A (ja) 2017-02-28 2025-04-24 前立腺癌検出

Country Status (8)

Country Link
US (3) US10934592B2 (enExample)
EP (1) EP3589732A4 (enExample)
JP (3) JP7356349B2 (enExample)
KR (2) KR20250006325A (enExample)
CN (2) CN118147307A (enExample)
AU (2) AU2018229294B2 (enExample)
CA (1) CA3054836A1 (enExample)
WO (1) WO2018160576A1 (enExample)

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US10184154B2 (en) 2014-09-26 2019-01-22 Mayo Foundation For Medical Education And Research Detecting cholangiocarcinoma
WO2016160454A1 (en) 2015-03-27 2016-10-06 Exact Sciences Corporation Detecting esophageal disorders
KR102892245B1 (ko) 2017-01-27 2025-11-27 이그젝트 싸이언스 디블롭먼트 컴패니, 엘엘씨 메틸화된 dna 분석에 의한 결장 신조직형성의 검출
WO2019108626A1 (en) 2017-11-30 2019-06-06 Mayo Foundation For Medical Education And Research Detecting breast cancer
US10648025B2 (en) 2017-12-13 2020-05-12 Exact Sciences Development Company, Llc Multiplex amplification detection assay II
CA3154354A1 (en) 2019-10-31 2021-05-06 William R. Taylor Detecting ovarian cancer
CN113122634A (zh) * 2020-01-14 2021-07-16 上海鹍远生物技术有限公司 检测dna甲基化的试剂及用途
CN113528658B (zh) * 2020-04-20 2024-09-13 江苏鹍远生物科技股份有限公司 甲状腺肿瘤良恶性鉴别模型及其应用
AU2021268631A1 (en) * 2020-05-04 2023-01-05 Mayo Foundation For Medical Education And Research Detecting pancreatic neuroendocrine tumors
WO2021237103A1 (en) 2020-05-22 2021-11-25 Wisconsin Alumni Research Foundation Epigenetic modification of select genes as markers of hypersomnolence
CN112779334B (zh) * 2021-02-01 2022-05-27 杭州医学院 一种用于前列腺癌早期筛查的甲基化标志物组合及筛选方法
KR20230105973A (ko) * 2022-01-05 2023-07-12 주식회사 젠큐릭스 특정 유전자의 CpG 메틸화 변화를 이용한 전립선암 진단용 조성물 및 이의 용도
CN116287227B (zh) * 2022-09-26 2024-11-05 武汉艾米森生命科技有限公司 用于诊断前列腺癌的试剂和试剂盒
US20250270650A1 (en) * 2023-12-12 2025-08-28 Flagship Pioneering Innovations Vi, Llc Methods for identifying genomic regions of low background methylation
CN118685521A (zh) * 2024-08-26 2024-09-24 湖南宏雅基因技术有限公司 一种用于前列腺癌检测的引物探针组合物及其应用
CN120005997B (zh) * 2025-01-10 2025-09-09 中南大学湘雅三医院 前列腺癌特异性甲基化标志物的应用和检测试剂

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