JP7336467B2 - 懸濁している細胞を分離する遠心分離機システム - Google Patents

懸濁している細胞を分離する遠心分離機システム Download PDF

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Publication number
JP7336467B2
JP7336467B2 JP2020567836A JP2020567836A JP7336467B2 JP 7336467 B2 JP7336467 B2 JP 7336467B2 JP 2020567836 A JP2020567836 A JP 2020567836A JP 2020567836 A JP2020567836 A JP 2020567836A JP 7336467 B2 JP7336467 B2 JP 7336467B2
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Japan
Prior art keywords
concentrate
liquid
chamber
separation
pump
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JP2020567836A
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English (en)
Japanese (ja)
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JPWO2019236895A5 (zh
JP2021526957A (ja
Inventor
ケスラー，エス
マーロ，ティー
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Pneumatic Scale Corp
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Pneumatic Scale Corp
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Publication of JPWO2019236895A5 publication Critical patent/JPWO2019236895A5/ja
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    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
    • B04B—CENTRIFUGES
    • B04B11/00—Feeding, charging, or discharging bowls
    • B04B11/04—Periodical feeding or discharging; Control arrangements therefor
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
    • B04B—CENTRIFUGES
    • B04B5/00—Other centrifuges
    • B04B5/04—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers
    • B04B5/0442—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers with means for adding or withdrawing liquid substances during the centrifugation, e.g. continuous centrifugation
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D21/00—Separation of suspended solid particles from liquids by sedimentation
    • B01D21/26—Separation of sediment aided by centrifugal force or centripetal force
    • B01D21/262—Separation of sediment aided by centrifugal force or centripetal force by using a centrifuge
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
    • B04B—CENTRIFUGES
    • B04B5/00—Other centrifuges
    • B04B5/04—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D21/00—Separation of suspended solid particles from liquids by sedimentation
    • B01D21/30—Control equipment
    • B01D21/32—Density control of clear liquid or sediment, e.g. optical control ; Control of physical properties
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
    • B04B—CENTRIFUGES
    • B04B11/00—Feeding, charging, or discharging bowls
    • B04B11/02—Continuous feeding or discharging; Control arrangements therefor
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
    • B04B—CENTRIFUGES
    • B04B11/00—Feeding, charging, or discharging bowls
    • B04B11/08—Skimmers or scrapers for discharging ; Regulating thereof
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
    • B04B—CENTRIFUGES
    • B04B11/00—Feeding, charging, or discharging bowls
    • B04B11/08—Skimmers or scrapers for discharging ; Regulating thereof
    • B04B11/082—Skimmers for discharging liquid
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
    • B04B—CENTRIFUGES
    • B04B13/00—Control arrangements specially designed for centrifuges; Programme control of centrifuges
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
    • B04B—CENTRIFUGES
    • B04B7/00—Elements of centrifuges
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
    • B04B—CENTRIFUGES
    • B04B7/00—Elements of centrifuges
    • B04B7/08—Rotary bowls
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M47/00—Means for after-treatment of the produced biomass or of the fermentation or metabolic products, e.g. storage of biomass
    • C12M47/02—Separating microorganisms from the culture medium; Concentration of biomass
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D2221/00—Applications of separation devices
    • B01D2221/10—Separation devices for use in medical, pharmaceutical or laboratory applications, e.g. separating amalgam from dental treatment residues
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
    • B04B—CENTRIFUGES
    • B04B5/00—Other centrifuges
    • B04B5/04—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers
    • B04B5/0442—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers with means for adding or withdrawing liquid substances during the centrifugation, e.g. continuous centrifugation
    • B04B2005/0464—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers with means for adding or withdrawing liquid substances during the centrifugation, e.g. continuous centrifugation with hollow or massive core in centrifuge bowl

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • Sustainable Development (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biomedical Technology (AREA)
  • Centrifugal Separators (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
JP2020567836A 2018-06-08 2019-06-06 懸濁している細胞を分離する遠心分離機システム Active JP7336467B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862682376P 2018-06-08 2018-06-08
US62/682,376 2018-06-08
PCT/US2019/035855 WO2019236895A1 (en) 2018-06-08 2019-06-06 Centrifuge system for separating cells in suspension

Publications (3)

Publication Number Publication Date
JP2021526957A JP2021526957A (ja) 2021-10-11
JPWO2019236895A5 JPWO2019236895A5 (zh) 2022-05-17
JP7336467B2 true JP7336467B2 (ja) 2023-08-31

Family

ID=68770662

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2020567836A Active JP7336467B2 (ja) 2018-06-08 2019-06-06 懸濁している細胞を分離する遠心分離機システム

Country Status (9)

Country Link
EP (1) EP3801920A4 (zh)
JP (1) JP7336467B2 (zh)
KR (2) KR102568314B1 (zh)
CN (2) CN112236236A (zh)
AU (2) AU2019280856B2 (zh)
BR (1) BR112020025083A2 (zh)
CA (1) CA3102600A1 (zh)
MX (2) MX2020011898A (zh)
WO (1) WO2019236895A1 (zh)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11065629B2 (en) * 2011-11-21 2021-07-20 Pneumatic Scale Corporation Centrifuge system for separating cells in suspension
US11878311B2 (en) * 2011-11-21 2024-01-23 Pneumatic Scale Corporation Centrifuge system for separating cells in suspension
US11957998B2 (en) * 2019-06-06 2024-04-16 Pneumatic Scale Corporation Centrifuge system for separating cells in suspension
EP4200077A1 (en) * 2020-08-22 2023-06-28 Sunil Mehta An automated centrifugation device and methods to continuously separate components from different mixtures
CN114682397B (zh) * 2022-03-28 2024-03-15 浙江大学 锥形液液轴向离心分离器及分离监控装置
US20230323264A1 (en) * 2022-04-07 2023-10-12 Mirror Biologics, Inc. Artificial lymph node bioreactor

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20150284671A1 (en) 2008-04-22 2015-10-08 Pneumatic Scale Corporation Single use centrifuge system for highly concentrated and/or turbid feeds

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DE941267C (de) * 1950-01-19 1956-04-05 Separator Ab Schleudermaschine fuer die kontinuierliche Trennung und Austragung fester Bestandteile aus einem Fluessigkeitsgemisch
CA1057254A (en) * 1976-05-14 1979-06-26 Baxter Travenol Laboratories Disposable centrifugal blood processing system
DE3231070A1 (de) * 1982-08-19 1984-08-23 Herwig 1000 Berlin Michel-Kim Vorrichtung zur austragung von in silos gelagerten stoffen
DE3771148D1 (de) * 1986-07-22 1991-08-08 Haemonetics Corp Zentrifugengehaeuse oder rotor fuer plasmapherese.
US5318500A (en) * 1992-10-15 1994-06-07 Eli Lilly And Company Method for controlling intermittently discharged centrifuges
CH687505A5 (fr) * 1993-01-29 1996-12-31 Elp Rochat Séparateur centrifuge pour fluides.
US5637217A (en) * 1995-01-25 1997-06-10 Fleetguard, Inc. Self-driven, cone-stack type centrifuge
DK0868215T3 (da) * 1995-12-01 2002-05-06 Baker Hughes Inc Fremgangsmåde og apparat til styring og overvågning af en centrifuge med kontinuerlig tilførsel
JPH09192215A (ja) * 1996-01-17 1997-07-29 Takaharu Nakane 遠心ボウル
JP3313572B2 (ja) * 1996-04-03 2002-08-12 ヘモネティクス・コーポレーション 血液処理用遠心分離器ボウル
DE19715661A1 (de) * 1997-04-16 1998-10-22 Mann & Hummel Filter Zentrifugenrotor
JP3817079B2 (ja) * 1998-10-05 2006-08-30 テルモ株式会社 血液成分採取装置
US6629919B2 (en) * 1999-06-03 2003-10-07 Haemonetics Corporation Core for blood processing apparatus
EP1688183A1 (fr) * 2005-02-03 2006-08-09 Jean-Denis Rochat Procede et dispositif jetable pour la separation par centrifugation d'un liquide physiologique
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KR102176554B1 (ko) * 2009-06-04 2020-11-09 게노마티카 인코포레이티드 발효액 성분들의 분리 방법
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Also Published As

Publication number Publication date
KR20210018796A (ko) 2021-02-18
BR112020025083A2 (pt) 2021-03-23
AU2019280856A1 (en) 2020-12-17
EP3801920A4 (en) 2022-07-13
KR20220039841A (ko) 2022-03-29
CA3102600A1 (en) 2019-12-12
CN115254458A (zh) 2022-11-01
EP3801920A1 (en) 2021-04-14
CN112236236A (zh) 2021-01-15
MX2022003223A (es) 2022-04-12
KR102568313B1 (ko) 2023-08-18
WO2019236895A1 (en) 2019-12-12
AU2019280856B2 (en) 2022-06-30
MX2020011898A (es) 2021-01-15
JP2021526957A (ja) 2021-10-11
AU2022204733A1 (en) 2022-07-21
KR102568314B1 (ko) 2023-08-18

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