JP7296992B2 - 細菌感染症の処置および予防のための新規オキソキノリジン化合物 - Google Patents

細菌感染症の処置および予防のための新規オキソキノリジン化合物 Download PDF

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Publication number
JP7296992B2
JP7296992B2 JP2020566736A JP2020566736A JP7296992B2 JP 7296992 B2 JP7296992 B2 JP 7296992B2 JP 2020566736 A JP2020566736 A JP 2020566736A JP 2020566736 A JP2020566736 A JP 2020566736A JP 7296992 B2 JP7296992 B2 JP 7296992B2
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methyl
pyrido
indol
oxo
quinolizine
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JP2020566736A
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Japanese (ja)
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JP2021525745A (ja
JP2021525745A5 (https=
Inventor
デイ，ファビアン
ディーン，シヤオ
フー，イミン
リウ，ヨーンチエン
シェン，ホーン
シー，ホウグワーン
タン，シュエフェイ
ジョウ，チェンガーン
ジョウ，ミーンウエイ
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F Hoffmann La Roche AG
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F Hoffmann La Roche AG
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
JP2020566736A 2018-05-28 2019-05-27 細菌感染症の処置および予防のための新規オキソキノリジン化合物 Active JP7296992B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CN2018088728 2018-05-28
CNPCT/CN2018/088728 2018-05-28
PCT/EP2019/063562 WO2019228940A1 (en) 2018-05-28 2019-05-27 Novel oxoquinolizine compounds for the treatment and prophylaxis of bacterial infection

Publications (3)

Publication Number Publication Date
JP2021525745A JP2021525745A (ja) 2021-09-27
JP2021525745A5 JP2021525745A5 (https=) 2022-06-01
JP7296992B2 true JP7296992B2 (ja) 2023-06-23

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ID=66912773

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JP2020566736A Active JP7296992B2 (ja) 2018-05-28 2019-05-27 細菌感染症の処置および予防のための新規オキソキノリジン化合物

Country Status (5)

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US (1) US20210238197A1 (https=)
EP (1) EP3802549B1 (https=)
JP (1) JP7296992B2 (https=)
CN (1) CN112204037A (https=)
WO (1) WO2019228940A1 (https=)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2020064661A1 (en) * 2018-09-26 2020-04-02 F. Hoffmann-La Roche Ag Substituted pyridoindoles for the treatment and prophylaxis of bacterial infection
CN113166174A (zh) * 2018-11-22 2021-07-23 豪夫迈·罗氏有限公司 用于治疗和预防细菌感染的游离氨基化合物
EP3887370B1 (en) * 2018-11-27 2023-01-18 F. Hoffmann-La Roche AG Tricyclic compounds for the treatment and prophylaxis of bacterial infection
WO2020109191A1 (en) * 2018-11-27 2020-06-04 F. Hoffmann-La Roche Ag Aryl compounds for the treatment and prophylaxis of bacterial infection
WO2020127624A1 (en) * 2018-12-20 2020-06-25 F. Hoffmann-La Roche Ag Oxopyrido[1,2-a]pyrimidine compounds for the treatment and prophylaxis of bacterial infection

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2003012670A (ja) 2001-04-10 2003-01-15 Sato Pharmaceutical Co Ltd 抗菌活性を有する４−オキソキノリジン系化合物
JP2014508173A (ja) 2011-03-15 2014-04-03 トリウス セラピューティックス インコーポレイテッド 三環式ジャイレース阻害薬
JP2020512372A (ja) 2017-03-30 2020-04-23 エフ．ホフマン−ラ ロシュ アーゲーＦ． Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ 細菌感染の治療及び予防のための新規ピリド［２，３−ｂ］インドール化合物

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
UY31676A1 (es) * 2008-02-28 2009-09-30 "derivados de 3-metil-imidiazo-[1,2-b]-piridazina"
WO2012047487A1 (en) * 2010-09-27 2012-04-12 Evolva Sa 2-pyridone antimicrobial compositions
PL2931716T3 (pl) * 2012-12-13 2017-04-28 Novartis Ag Pochodne pirydonu i ich zastosowanie w leczeniu gruźlicy
WO2020064661A1 (en) * 2018-09-26 2020-04-02 F. Hoffmann-La Roche Ag Substituted pyridoindoles for the treatment and prophylaxis of bacterial infection

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2003012670A (ja) 2001-04-10 2003-01-15 Sato Pharmaceutical Co Ltd 抗菌活性を有する４−オキソキノリジン系化合物
JP2014508173A (ja) 2011-03-15 2014-04-03 トリウス セラピューティックス インコーポレイテッド 三環式ジャイレース阻害薬
JP2020512372A (ja) 2017-03-30 2020-04-23 エフ．ホフマン−ラ ロシュ アーゲーＦ． Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ 細菌感染の治療及び予防のための新規ピリド［２，３−ｂ］インドール化合物

Also Published As

Publication number Publication date
EP3802549B1 (en) 2023-03-01
EP3802549A1 (en) 2021-04-14
US20210238197A1 (en) 2021-08-05
CN112204037A (zh) 2021-01-08
JP2021525745A (ja) 2021-09-27
WO2019228940A1 (en) 2019-12-05

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