JP7293236B2 - 自動試料処理のための方法およびシステム - Google Patents

自動試料処理のための方法およびシステム Download PDF

Info

Publication number
JP7293236B2
JP7293236B2 JP2020536921A JP2020536921A JP7293236B2 JP 7293236 B2 JP7293236 B2 JP 7293236B2 JP 2020536921 A JP2020536921 A JP 2020536921A JP 2020536921 A JP2020536921 A JP 2020536921A JP 7293236 B2 JP7293236 B2 JP 7293236B2
Authority
JP
Japan
Prior art keywords
sample
conduit
chamber
sample chamber
assay tube
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
JP2020536921A
Other languages
English (en)
Japanese (ja)
Other versions
JP2020534545A5 (enExample
JP2020534545A (ja
Inventor
デジョン,マーク
コックス,クリストファー
Original Assignee
バイオミーム インコーポレイテッド
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by バイオミーム インコーポレイテッド filed Critical バイオミーム インコーポレイテッド
Publication of JP2020534545A publication Critical patent/JP2020534545A/ja
Publication of JP2020534545A5 publication Critical patent/JP2020534545A5/ja
Priority to JP2023094260A priority Critical patent/JP2023116623A/ja
Application granted granted Critical
Publication of JP7293236B2 publication Critical patent/JP7293236B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Images

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502715—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by interfacing components, e.g. fluidic, electrical, optical or mechanical interfaces
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/508—Rigid containers without fluid transport within
    • B01L3/5082—Test tubes per se
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/52—Containers specially adapted for storing or dispensing a reagent
    • B01L3/527—Containers specially adapted for storing or dispensing a reagent for a plurality of reagents
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L7/00—Heating or cooling apparatus; Heat insulating devices
    • B01L7/52—Heating or cooling apparatus; Heat insulating devices with provision for submitting samples to a predetermined sequence of different temperatures, e.g. for treating nucleic acid samples
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/686—Polymerase chain reaction [PCR]
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/10—Integrating sample preparation and analysis in single entity, e.g. lab-on-a-chip concept
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/16—Reagents, handling or storing thereof
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/06—Auxiliary integrated devices, integrated components
    • B01L2300/0681—Filter
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0809—Geometry, shape and general structure rectangular shaped
    • B01L2300/0816—Cards, e.g. flat sample carriers usually with flow in two horizontal directions
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
    • B01L2300/0867—Multiple inlets and one sample wells, e.g. mixing, dilution
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
    • B01L2300/0874—Three dimensional network
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0475—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure
    • B01L2400/0487—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure fluid pressure, pneumatics
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/06—Valves, specific forms thereof
    • B01L2400/0633—Valves, specific forms thereof with moving parts
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/06—Valves, specific forms thereof
    • B01L2400/0633—Valves, specific forms thereof with moving parts
    • B01L2400/0661—Valves, specific forms thereof with moving parts shape memory polymer valves
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Health & Medical Sciences (AREA)
  • Clinical Laboratory Science (AREA)
  • Analytical Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Hematology (AREA)
  • Organic Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Molecular Biology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
JP2020536921A 2017-09-15 2018-09-14 自動試料処理のための方法およびシステム Active JP7293236B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2023094260A JP2023116623A (ja) 2017-09-15 2023-06-07 自動試料処理のための方法およびシステム

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201762559173P 2017-09-15 2017-09-15
US62/559,173 2017-09-15
US201862688861P 2018-06-22 2018-06-22
US62/688,861 2018-06-22
PCT/US2018/051228 WO2019055875A2 (en) 2017-09-15 2018-09-14 METHODS AND SYSTEMS FOR AUTOMATIC SAMPLE PROCESSING

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2023094260A Division JP2023116623A (ja) 2017-09-15 2023-06-07 自動試料処理のための方法およびシステム

Publications (3)

Publication Number Publication Date
JP2020534545A JP2020534545A (ja) 2020-11-26
JP2020534545A5 JP2020534545A5 (enExample) 2021-10-21
JP7293236B2 true JP7293236B2 (ja) 2023-06-19

Family

ID=65723119

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2020536921A Active JP7293236B2 (ja) 2017-09-15 2018-09-14 自動試料処理のための方法およびシステム
JP2023094260A Ceased JP2023116623A (ja) 2017-09-15 2023-06-07 自動試料処理のための方法およびシステム

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2023094260A Ceased JP2023116623A (ja) 2017-09-15 2023-06-07 自動試料処理のための方法およびシステム

Country Status (5)

Country Link
US (2) US12023666B2 (enExample)
EP (1) EP3682024A4 (enExample)
JP (2) JP7293236B2 (enExample)
CN (1) CN111356768A (enExample)
WO (1) WO2019055875A2 (enExample)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110237880A (zh) 2013-01-18 2019-09-17 生米公司 分析设备
CN105765363B (zh) 2013-11-01 2020-05-08 生米公司 样品提取和制备装置
JP7293236B2 (ja) 2017-09-15 2023-06-19 バイオミーム インコーポレイテッド 自動試料処理のための方法およびシステム
CN111712581A (zh) 2017-12-15 2020-09-25 生米公司 用于分析样品的便携式装置和方法
EP3942281A4 (en) 2019-03-21 2022-11-16 Biomeme, Inc. MULTIFUNCTIONAL ANALYTICAL DEVICES
US20220193678A1 (en) * 2019-04-08 2022-06-23 Technion Research And Development Foundation, Ltd. Multiplexed array of nanoliter droplet array device
CA3141275A1 (en) * 2019-06-18 2020-12-24 Biomeme, Inc. Systems for sample analysis
WO2022061105A1 (en) 2020-09-18 2022-03-24 Biomeme, Inc. Portable devices and methods for analyzing samples
WO2022074241A1 (en) * 2020-10-09 2022-04-14 Swissdecode Sa Food certification system
US11986818B2 (en) * 2022-03-24 2024-05-21 ODH IP Corp. Portable formulating apparatus and system
US20240299935A1 (en) * 2023-03-06 2024-09-12 Fluidion US Inc. Reagent Delivery System for Microfluidic Chemical Analyzer
CN121794061A (zh) * 2023-08-14 2026-04-03 生命科技股份有限公司 使用ChemFET传感器阵列进行细胞分析的系统和方法

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2013525763A (ja) 2010-04-16 2013-06-20 オプコ・ダイアグノスティクス・リミテッド・ライアビリティ・カンパニー 試料の分析のためのシステムおよびデバイス
WO2016124907A1 (en) 2015-02-02 2016-08-11 Atlas Genetics Limited Instrument for performing a diagnostic test on a fluidic cartridge
WO2017112911A1 (en) 2015-12-22 2017-06-29 Canon U.S. Life Sciences, Inc Sample-to-answer system for microorganism detection featuring target enrichment, amplification and detection

Family Cites Families (88)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3757780A (en) 1971-02-25 1973-09-11 Ishikawa Susakusho Kk Needle assembly with longitudinally movable filter
DK229389D0 (da) 1989-05-10 1989-05-10 Karin Sundberg Fremgangsmaade og aparat til udtagning af en proeve af celleholdigt fostervand fra amnionhulen
US5151192A (en) 1990-07-13 1992-09-29 Pall Corporation Method for removing heparin from blood or plasma
CA2130013C (en) 1993-09-10 1999-03-30 Rolf Moser Apparatus for automatic performance of temperature cycles
DE4432654C2 (de) 1994-09-14 1998-03-26 Qiagen Gmbh Verfahren zur Isolierung von Nukleinsäuren aus natürlichen Quellen
EP0688570A3 (de) 1994-06-21 1996-04-03 Wilhelm Gmeiner Insulinspritze
US6800452B1 (en) 1994-08-08 2004-10-05 Science Applications International Corporation Automated methods for simultaneously performing a plurality of signal-based assays
US5529391A (en) 1994-09-22 1996-06-25 Duke University Magnetic stirring and heating/cooling apparatus
US6884357B2 (en) 1995-02-21 2005-04-26 Iqbal Waheed Siddiqi Apparatus and method for processing magnetic particles
GB9506312D0 (en) 1995-03-28 1995-05-17 Medical Res Council Improvements in or relating to sample processing
US5849488A (en) 1996-02-27 1998-12-15 Oulutech Ltd. DNA-sequence-based diagnosis of mastitis from a milk sample
EP1442794B1 (en) 1996-06-04 2006-03-29 University Of Utah Research Foundation System and method for carrying out and monitoring biological processes
WO1998038487A2 (en) 1997-02-28 1998-09-03 Cepheid Heat exchanging, optically interrogated chemical reaction assembly
US6958392B2 (en) 1998-10-09 2005-10-25 Whatman, Inc. Methods for the isolation of nucleic acids and for quantitative DNA extraction and detection for leukocyte evaluation in blood products
GB2344526B (en) 1999-01-12 2001-05-23 Dumaresq Lucas Alison Jayne Syringe with filter,and filter therefor
US6391541B1 (en) 1999-05-28 2002-05-21 Kurt E. Petersen Apparatus for analyzing a fluid sample
IL146776A (en) 2001-11-27 2010-11-30 Yoram Alroy Device for blood sampling under vacuum conditions
US7452507B2 (en) 2002-08-02 2008-11-18 Sandia Corporation Portable apparatus for separating sample and detecting target analytes
GB0226863D0 (en) 2002-11-19 2002-12-24 Biogene Ltd Improvements in and relating to reaction vessels and reaction apparatus for use with such vessels
US20040216175A1 (en) 2003-02-17 2004-10-28 Hyesook Kim Detection and identification of toxicants by measurement of gene expression profile
DE20302819U1 (de) 2003-02-21 2003-05-08 Filtertek, S.A., Plailly Filter für medizinische und Laborzwecke, insbesondere für Blutanalysen u.dgl.
JP4880468B2 (ja) 2003-05-29 2012-02-22 アジレント・テクノロジーズ・インク 固相抽出装置を作製する方法、および分析用のサンプルを作製する方法
GB0317044D0 (en) 2003-07-21 2003-08-27 Dna Res Innovations Ltd Nucleic acid isolation
KR100552706B1 (ko) 2004-03-12 2006-02-20 삼성전자주식회사 핵산 증폭 방법 및 장치
US7046359B2 (en) 2004-06-30 2006-05-16 Chemimage Corporation System and method for dynamic chemical imaging
US7167755B2 (en) 2004-10-05 2007-01-23 Cardiac Pacemakers, Inc. Adaptive software configuration for a medical device
DE102005001788A1 (de) 2005-01-12 2006-07-20 Universität Zürich Verfahren und Kit zur Detektion von Mycobakterium avium subsp. paratuberculosis (MAP) in Proben von Kot, Körpergewebe oder Milch
US7404493B2 (en) 2005-03-23 2008-07-29 Entegris, Inc. Filter device including pleated filter incorporated in a housing
PL1866637T3 (pl) 2005-04-01 2016-07-29 Polymer Technology Systems Inc Składnik do badania płynu ustrojowego do detekcji analitu
CN100336068C (zh) 2005-04-21 2007-09-05 中国科学院上海微系统与信息技术研究所 用于驱动聚合酶链式反应微芯片阵列的温度控制方法及装置
US7577064B2 (en) 2005-07-11 2009-08-18 Tecan Trading Ag Microplate reader with intelligent filter slide
JP5063616B2 (ja) 2006-02-03 2012-10-31 インテジェニックス インコーポレイテッド マイクロ流体デバイス
US9114398B2 (en) 2006-11-29 2015-08-25 Canon U.S. Life Sciences, Inc. Device and method for digital multiplex PCR assays
US9575655B2 (en) 2006-12-29 2017-02-21 Nokia Technologies Oy Transparent layer application
MX2009008510A (es) 2007-02-09 2010-01-15 Acceleron Pharma Inc Antagonistas de activina-actriia y usos para promover el crecimiento de huesos en pacientes con cancer.
US9618139B2 (en) 2007-07-13 2017-04-11 Handylab, Inc. Integrated heater and magnetic separator
WO2009036956A1 (en) 2007-09-19 2009-03-26 University Of Bern Detection of staphylococcus aureus in bovine mastitic milk
CL2008003007A1 (es) 2007-10-12 2009-10-02 Bigtec Private Ltd Un micro chip con capas de ceramicas de coccion conjunta a baja temperatura (ltcc) formando una camara de reaccion, anillos conductores que rodean a la camara de reaccion y un calentador que suministra calor a los anillos, el metodo de fabricacion del micro chip y un micro dispositivo de reaccion en cadena de polimerasa (pcr).
US7759112B2 (en) 2007-10-31 2010-07-20 Akonni Biosystems, Inc. Apparatus, system, and method for purifying nucleic acids
US20090111193A1 (en) 2007-10-31 2009-04-30 Cooney Christopher G Sample preparation device
US9349127B2 (en) 2007-11-29 2016-05-24 Visa Usa Inc. Serial number and payment data based payment card processing
EP2332087B1 (en) 2008-07-25 2020-04-22 Fundação D. Anna Sommer Champalimaud E Dr. Carlos Montez Champalimaud Systems and methods of treating, diagnosing and predicting the occurrence of a medical condition
US20100204462A1 (en) 2008-10-13 2010-08-12 Thomas Walter Pipette tip with separation material
CH700127A1 (de) 2008-12-17 2010-06-30 Tecan Trading Ag System und Vorrichtung zur Aufarbeitung biologischer Proben und zur Manipulation von Flüssigkeiten mit biologischen Proben.
KR20100101526A (ko) 2009-03-09 2010-09-17 삼성전자주식회사 스트로보 박막 화학 분석 장치 및 이를 이용한 분석 방법
JP4911264B2 (ja) 2009-07-09 2012-04-04 凸版印刷株式会社 核酸抽出用キット、核酸抽出方法及び核酸抽出装置
CN201837588U (zh) 2009-09-09 2011-05-18 海利克斯公司 用于多个反应的光学系统
FI4060325T3 (fi) * 2009-12-07 2024-09-25 Meso Scale Technologies Llc Määrityskasetin lukija
MX350399B (es) 2009-12-18 2017-09-06 Novozymes Inc Metodos para producir polipeptidos en mutantes de trichoderma deficientes en proteasa.
CA2796586C (en) * 2010-02-23 2017-10-24 Genturadx-Usa, Inc. Apparatus and methods for integrated sample preparation, reaction and detection
CN102906573B (zh) 2010-02-23 2015-02-18 瑞昂尼克公司 独立式生物检测装置、方法和应用
JP5708639B2 (ja) 2010-03-31 2015-04-30 凸版印刷株式会社 多孔質フィルターカラム及びそれを用いた試薬カートリッジ並びに核酸精製キット
WO2011149857A1 (en) 2010-05-24 2011-12-01 Abbott Diabetes Care Inc. Method and system for updating a medical device
GB201016014D0 (en) 2010-09-24 2010-11-10 Epistem Ltd Thermal cycler
US8454892B1 (en) 2010-10-15 2013-06-04 The United States Of America As Represented By The Secretary Of The Army Chemical agent detection system for fluid media
GB201018624D0 (en) 2010-11-04 2010-12-22 Epistem Ltd Reaction vessel
CN110220876B (zh) 2011-01-10 2022-04-26 伊鲁米那股份有限公司 用于生物或化学分析的样品的成像方法
JP5817050B2 (ja) 2011-04-08 2015-11-18 ザマート カンパニー,リミテッド フィルターニードル
WO2012151473A2 (en) 2011-05-04 2012-11-08 Luminex Corporation Apparatus and methods for integrated sample preparation, reaction and detection
US20140242612A1 (en) 2011-07-14 2014-08-28 Shuqi Wang System and method for integration of mobile device imaging with microchip elisa
JP2014530358A (ja) * 2011-09-25 2014-11-17 セラノス, インコーポレイテッド 多重分析のためのシステム及び方法
US9810704B2 (en) * 2013-02-18 2017-11-07 Theranos, Inc. Systems and methods for multi-analysis
US10865440B2 (en) * 2011-10-21 2020-12-15 IntegenX, Inc. Sample preparation, processing and analysis systems
US8894946B2 (en) * 2011-10-21 2014-11-25 Integenx Inc. Sample preparation, processing and analysis systems
AU2013225728B2 (en) 2012-03-01 2018-07-26 Ortho-Clinical Diagnostics, Inc. Interactive test device and apparatus with timing mechanism
WO2013133725A1 (en) 2012-03-09 2013-09-12 Rawle Christopher Bruce Portable device for detecting molecule(s)
US20130331298A1 (en) * 2012-06-06 2013-12-12 Great Basin Scientific Analyzer and disposable cartridge for molecular in vitro diagnostics
CN104602783B (zh) 2012-06-25 2018-10-30 歌瑞欧有限公司 过滤容器组件和方法
JP2016509206A (ja) 2012-12-21 2016-03-24 マイクロニクス, インコーポレイテッド 携帯型蛍光検出システムおよびマイクロアッセイカートリッジ
CN110237880A (zh) 2013-01-18 2019-09-17 生米公司 分析设备
US11286513B2 (en) 2013-05-31 2022-03-29 3I Diagnostics, Inc. Rapid microbial detection
GB2516666B (en) 2013-07-29 2015-09-09 Atlas Genetics Ltd Fluidic cartridge for nucleic acid amplification and detection
WO2015054245A1 (en) 2013-10-07 2015-04-16 Douglas Scientific Portable testing device for analyzing biological samples
CN105765363B (zh) 2013-11-01 2020-05-08 生米公司 样品提取和制备装置
US9535676B1 (en) 2014-04-04 2017-01-03 Seagate Technology Llc Remote feature activation
CN105092543A (zh) 2014-05-12 2015-11-25 绍兴安尼特微电子科技有限公司 一种便携式荧光定量pcr检测仪
KR102738114B1 (ko) 2014-08-08 2024-12-06 퀀텀-에스아이 인코포레이티드 분자들을 프로빙, 검출 및 분석하기 위한 광학계 및 검정 칩
US10317420B2 (en) 2014-12-15 2019-06-11 Luminex Corporation Detailed assay protocol specification
US9921105B2 (en) 2015-02-05 2018-03-20 International Business Machines Corporation Mobile cellular spectroscopy
EP3719481B1 (en) 2015-02-06 2023-03-29 Life Technologies Corporation An optical instrument for biological analysis
CN109642198A (zh) * 2016-02-10 2019-04-16 卡尤迪生物科技(北京)有限公司 用于分析核酸的方法和系统
WO2017201505A2 (en) * 2016-05-19 2017-11-23 Plasmotica, LLC Apparatus and method for programmable spatially selective nanoscale surface functionalization, self-flowing micorfluidic analytical chip, and stand alone microfluidic analytical chip device
JP7293236B2 (ja) 2017-09-15 2023-06-19 バイオミーム インコーポレイテッド 自動試料処理のための方法およびシステム
CN111712581A (zh) 2017-12-15 2020-09-25 生米公司 用于分析样品的便携式装置和方法
WO2019143812A1 (en) 2018-01-18 2019-07-25 Biomeme, Inc. Methods of assaying for the presence of microorganisms
EP3942281A4 (en) 2019-03-21 2022-11-16 Biomeme, Inc. MULTIFUNCTIONAL ANALYTICAL DEVICES
CA3141275A1 (en) 2019-06-18 2020-12-24 Biomeme, Inc. Systems for sample analysis
WO2022061105A1 (en) 2020-09-18 2022-03-24 Biomeme, Inc. Portable devices and methods for analyzing samples

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2013525763A (ja) 2010-04-16 2013-06-20 オプコ・ダイアグノスティクス・リミテッド・ライアビリティ・カンパニー 試料の分析のためのシステムおよびデバイス
WO2016124907A1 (en) 2015-02-02 2016-08-11 Atlas Genetics Limited Instrument for performing a diagnostic test on a fluidic cartridge
WO2017112911A1 (en) 2015-12-22 2017-06-29 Canon U.S. Life Sciences, Inc Sample-to-answer system for microorganism detection featuring target enrichment, amplification and detection

Also Published As

Publication number Publication date
WO2019055875A2 (en) 2019-03-21
EP3682024A4 (en) 2021-05-12
EP3682024A2 (en) 2020-07-22
JP2020534545A (ja) 2020-11-26
WO2019055875A3 (en) 2020-04-09
US12023666B2 (en) 2024-07-02
CN111356768A (zh) 2020-06-30
US20250121369A1 (en) 2025-04-17
US20200276582A1 (en) 2020-09-03
JP2023116623A (ja) 2023-08-22

Similar Documents

Publication Publication Date Title
US20250121369A1 (en) Methods and systems for automated sample processing
US20220186325A1 (en) Systems for sample analysis
Zhang et al. A surface topography assisted droplet manipulation platform for biomarker detection and pathogen identification
CN101990516B (zh) 多用试样准备系统及其在集成分析系统中的使用
US9243288B2 (en) Cartridge with lysis chamber and droplet generator
CN106660042B (zh) 微流体装置
US11904315B2 (en) System and self-metering cartridges for point of care bioassays
TW200406487A (en) Microfluidic system for analyzing nucleic acids
MXPA05004606A (es) Sistema microfluidico apara analisis de acidos nucleicos.
JP5691187B2 (ja) 核酸増幅反応用マイクロチップ及びその製造方法
CN113454200A (zh) 用于核酸扩增的微流体反应腔室
US10590477B2 (en) Method and apparatus for purifying nucleic acids and performing polymerase chain reaction assays using an immiscible fluid
WO2016081549A1 (en) Compositions, methods, systems and kits for nucleic acid amplification and analysis
JP2009284769A (ja) マイクロ基板
US11898197B2 (en) System and self-metering cartridges for point of care bioassays
WO2006046433A1 (ja) 遺伝子検査用マイクロリアクタ
US20190291113A1 (en) Methods and systems for conducting a chemical or biological reaction
Parthasarathy et al. Developments in microfluidic integrated lab-on-chip devices for DNA biosensing towards unifying the emergence of nanobiosensor
US20190184402A1 (en) Methods and systems for analyzing nucleic acids
EP4100545B1 (en) Nucleic acid amplification
Cooney et al. A plastic, disposable microfluidic flow cell for coupled on-chip PCR and microarray detection of infectious agents
Pham et al. Fabrication of 3D continuous-flow reverse-transcription polymerase chain reaction microdevice integrated with on-chip fluorescence detection for semi-quantitative assessment of gene expression
US12428674B2 (en) System and self-metering cartridges for point of care bioassays
WO2025024604A1 (en) Diagnostic cartridge and architecture
EP2785460B1 (en) Systems and methods for sampling of amplification products

Legal Events

Date Code Title Description
A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20210913

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20210913

A977 Report on retrieval

Free format text: JAPANESE INTERMEDIATE CODE: A971007

Effective date: 20220831

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20220913

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20221213

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20230301

TRDD Decision of grant or rejection written
A01 Written decision to grant a patent or to grant a registration (utility model)

Free format text: JAPANESE INTERMEDIATE CODE: A01

Effective date: 20230509

A61 First payment of annual fees (during grant procedure)

Free format text: JAPANESE INTERMEDIATE CODE: A61

Effective date: 20230607

R150 Certificate of patent or registration of utility model

Ref document number: 7293236

Country of ref document: JP

Free format text: JAPANESE INTERMEDIATE CODE: R150