CN111356768A - 用于自动化样品处理的方法和系统 - Google Patents

用于自动化样品处理的方法和系统 Download PDF

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Publication number
CN111356768A
CN111356768A CN201880073932.5A CN201880073932A CN111356768A CN 111356768 A CN111356768 A CN 111356768A CN 201880073932 A CN201880073932 A CN 201880073932A CN 111356768 A CN111356768 A CN 111356768A
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CN
China
Prior art keywords
sample
fluid flow
conduit
fluid
chamber
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Pending
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CN201880073932.5A
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English (en)
Chinese (zh)
Inventor
马克·德约翰
克里斯多佛·考克斯
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Biomeme Inc
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Biomeme Inc
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Publication of CN111356768A publication Critical patent/CN111356768A/zh
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    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502715—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by interfacing components, e.g. fluidic, electrical, optical or mechanical interfaces
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/508—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above
    • B01L3/5082—Test tubes per se
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/52—Containers specially adapted for storing or dispensing a reagent
    • B01L3/527—Containers specially adapted for storing or dispensing a reagent for a plurality of reagents
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L7/00—Heating or cooling apparatus; Heat insulating devices
    • B01L7/52—Heating or cooling apparatus; Heat insulating devices with provision for submitting samples to a predetermined sequence of different temperatures, e.g. for treating nucleic acid samples
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/686—Polymerase chain reaction [PCR]
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/10—Integrating sample preparation and analysis in single entity, e.g. lab-on-a-chip concept
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/16—Reagents, handling or storing thereof
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/06—Auxiliary integrated devices, integrated components
    • B01L2300/0681—Filter
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0809—Geometry, shape and general structure rectangular shaped
    • B01L2300/0816—Cards, e.g. flat sample carriers usually with flow in two horizontal directions
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
    • B01L2300/0867—Multiple inlets and one sample wells, e.g. mixing, dilution
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
    • B01L2300/0874—Three dimensional network
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0475—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure
    • B01L2400/0487—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure fluid pressure, pneumatics
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/06—Valves, specific forms thereof
    • B01L2400/0633—Valves, specific forms thereof with moving parts
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/06—Valves, specific forms thereof
    • B01L2400/0633—Valves, specific forms thereof with moving parts
    • B01L2400/0661—Valves, specific forms thereof with moving parts shape memory polymer valves
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Health & Medical Sciences (AREA)
  • Clinical Laboratory Science (AREA)
  • Analytical Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Hematology (AREA)
  • Organic Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Molecular Biology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
CN201880073932.5A 2017-09-15 2018-09-14 用于自动化样品处理的方法和系统 Pending CN111356768A (zh)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201762559173P 2017-09-15 2017-09-15
US62/559,173 2017-09-15
US201862688861P 2018-06-22 2018-06-22
US62/688,861 2018-06-22
PCT/US2018/051228 WO2019055875A2 (en) 2017-09-15 2018-09-14 METHODS AND SYSTEMS FOR AUTOMATIC SAMPLE PROCESSING

Publications (1)

Publication Number Publication Date
CN111356768A true CN111356768A (zh) 2020-06-30

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Family Applications (1)

Application Number Title Priority Date Filing Date
CN201880073932.5A Pending CN111356768A (zh) 2017-09-15 2018-09-14 用于自动化样品处理的方法和系统

Country Status (5)

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US (2) US12023666B2 (enExample)
EP (1) EP3682024A4 (enExample)
JP (2) JP7293236B2 (enExample)
CN (1) CN111356768A (enExample)
WO (1) WO2019055875A2 (enExample)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP4480582A1 (en) 2013-01-18 2024-12-25 Biomeme, Inc. Analytic device
CA2928843C (en) 2013-11-01 2021-11-23 Marc Dominic Dejohn Sample extraction and preparation device
WO2019055875A2 (en) 2017-09-15 2019-03-21 Biomeme, Inc. METHODS AND SYSTEMS FOR AUTOMATIC SAMPLE PROCESSING
JP7524061B2 (ja) 2017-12-15 2024-07-29 バイオミーム インコーポレイテッド サンプルを分析するためのポータブル装置及び方法
CN113874708A (zh) 2019-03-21 2021-12-31 生米公司 多功能分析装置
WO2020208629A1 (en) * 2019-04-08 2020-10-15 Technion Research & Development Foundation Limited Multiplexed array of nanoliter droplet array devices
CA3141275A1 (en) * 2019-06-18 2020-12-24 Biomeme, Inc. Systems for sample analysis
CA3192080A1 (en) 2020-09-18 2022-03-24 Marc DEJOHN Portable devices and methods for analyzing samples
EP4225496A1 (en) * 2020-10-09 2023-08-16 SwissDeCode SA Food certification system
WO2023224721A2 (en) * 2022-03-24 2023-11-23 ODH IP Corp. Portable formulating apparatus and system
WO2025038385A1 (en) * 2023-08-14 2025-02-20 Life Technologies Corporation Systems and methods for cell analysis using chemfet sensor arrays

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20160069921A1 (en) * 2011-09-25 2016-03-10 Theranos, Inc. Systems and methods for multi-analysis
WO2017112911A1 (en) * 2015-12-22 2017-06-29 Canon U.S. Life Sciences, Inc Sample-to-answer system for microorganism detection featuring target enrichment, amplification and detection
WO2017139447A1 (en) * 2016-02-10 2017-08-17 Coyote Bioscience Usa Inc. Methods and systems for analyzing nucleic acids

Family Cites Families (88)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3757780A (en) 1971-02-25 1973-09-11 Ishikawa Susakusho Kk Needle assembly with longitudinally movable filter
DK229389D0 (da) 1989-05-10 1989-05-10 Karin Sundberg Fremgangsmaade og aparat til udtagning af en proeve af celleholdigt fostervand fra amnionhulen
US5151192A (en) 1990-07-13 1992-09-29 Pall Corporation Method for removing heparin from blood or plasma
CA2130013C (en) 1993-09-10 1999-03-30 Rolf Moser Apparatus for automatic performance of temperature cycles
DE4432654C2 (de) 1994-09-14 1998-03-26 Qiagen Gmbh Verfahren zur Isolierung von Nukleinsäuren aus natürlichen Quellen
EP0688570A3 (de) 1994-06-21 1996-04-03 Wilhelm Gmeiner Insulinspritze
US6800452B1 (en) 1994-08-08 2004-10-05 Science Applications International Corporation Automated methods for simultaneously performing a plurality of signal-based assays
US5529391A (en) 1994-09-22 1996-06-25 Duke University Magnetic stirring and heating/cooling apparatus
US6884357B2 (en) 1995-02-21 2005-04-26 Iqbal Waheed Siddiqi Apparatus and method for processing magnetic particles
GB9506312D0 (en) 1995-03-28 1995-05-17 Medical Res Council Improvements in or relating to sample processing
US5849488A (en) 1996-02-27 1998-12-15 Oulutech Ltd. DNA-sequence-based diagnosis of mastitis from a milk sample
EP1674585B1 (en) 1996-06-04 2010-10-20 University of Utah Research Foundation Apparatus for performing PCR and monitoring the reaction in real time during temperature cycling
EP2333520B1 (en) 1997-02-28 2014-06-25 Cepheid Heat exchanging, optically interrogated chemical reaction assembly
US6958392B2 (en) 1998-10-09 2005-10-25 Whatman, Inc. Methods for the isolation of nucleic acids and for quantitative DNA extraction and detection for leukocyte evaluation in blood products
GB2344526B (en) 1999-01-12 2001-05-23 Dumaresq Lucas Alison Jayne Syringe with filter,and filter therefor
DE60014676T2 (de) 1999-05-28 2005-11-17 Cepheid, Sunnyvale Vorrichtung und verfahren zur analyse flüssiger proben
IL146776A (en) 2001-11-27 2010-11-30 Yoram Alroy Device for blood sampling under vacuum conditions
US7452507B2 (en) 2002-08-02 2008-11-18 Sandia Corporation Portable apparatus for separating sample and detecting target analytes
GB0226863D0 (en) 2002-11-19 2002-12-24 Biogene Ltd Improvements in and relating to reaction vessels and reaction apparatus for use with such vessels
US20040216175A1 (en) 2003-02-17 2004-10-28 Hyesook Kim Detection and identification of toxicants by measurement of gene expression profile
DE20302819U1 (de) 2003-02-21 2003-05-08 Filtertek, S.A., Plailly Filter für medizinische und Laborzwecke, insbesondere für Blutanalysen u.dgl.
GB2418249B8 (en) 2003-05-29 2012-04-04 Varian Inc Solid phase extraction pipette
GB0317044D0 (en) 2003-07-21 2003-08-27 Dna Res Innovations Ltd Nucleic acid isolation
KR100552706B1 (ko) 2004-03-12 2006-02-20 삼성전자주식회사 핵산 증폭 방법 및 장치
US7046359B2 (en) 2004-06-30 2006-05-16 Chemimage Corporation System and method for dynamic chemical imaging
US7167755B2 (en) 2004-10-05 2007-01-23 Cardiac Pacemakers, Inc. Adaptive software configuration for a medical device
DE102005001788A1 (de) 2005-01-12 2006-07-20 Universität Zürich Verfahren und Kit zur Detektion von Mycobakterium avium subsp. paratuberculosis (MAP) in Proben von Kot, Körpergewebe oder Milch
US7404493B2 (en) 2005-03-23 2008-07-29 Entegris, Inc. Filter device including pleated filter incorporated in a housing
CA2601720C (en) 2005-04-01 2014-08-12 Advanced Medical Products Gmbh Body fluid testing component for analyte detection
CN100336068C (zh) 2005-04-21 2007-09-05 中国科学院上海微系统与信息技术研究所 用于驱动聚合酶链式反应微芯片阵列的温度控制方法及装置
US7577064B2 (en) 2005-07-11 2009-08-18 Tecan Trading Ag Microplate reader with intelligent filter slide
JP5063616B2 (ja) 2006-02-03 2012-10-31 インテジェニックス インコーポレイテッド マイクロ流体デバイス
US9114398B2 (en) 2006-11-29 2015-08-25 Canon U.S. Life Sciences, Inc. Device and method for digital multiplex PCR assays
US9575655B2 (en) 2006-12-29 2017-02-21 Nokia Technologies Oy Transparent layer application
TWI606062B (zh) 2007-02-09 2017-11-21 艾瑟勒朗法瑪公司 包含ＡｃｔＲＩＩａ-Ｆｃ融合蛋白的醫藥組合物；ＡｃｔＲＩＩａ-Ｆｃ融合蛋白於治療或預防與癌症相關的骨質流失之用途；ＡｃｔＲＩＩａ-Ｆｃ融合蛋白於治療或預防多發性骨髓瘤之用途
US9618139B2 (en) 2007-07-13 2017-04-11 Handylab, Inc. Integrated heater and magnetic separator
WO2009036956A1 (en) 2007-09-19 2009-03-26 University Of Bern Detection of staphylococcus aureus in bovine mastitic milk
PE20090965A1 (es) 2007-10-12 2009-07-13 Bigtec Private Ltd Micro chip
US20090111193A1 (en) 2007-10-31 2009-04-30 Cooney Christopher G Sample preparation device
US7759112B2 (en) 2007-10-31 2010-07-20 Akonni Biosystems, Inc. Apparatus, system, and method for purifying nucleic acids
US9349127B2 (en) 2007-11-29 2016-05-24 Visa Usa Inc. Serial number and payment data based payment card processing
US9858389B2 (en) 2008-07-25 2018-01-02 Fundação D. Anna De Sommer Champalimaud E Dr. Carlos Montez Champalimaud Method and system for determining the risk of occurrence of prostate cancer
US20100204462A1 (en) 2008-10-13 2010-08-12 Thomas Walter Pipette tip with separation material
CH700127A1 (de) 2008-12-17 2010-06-30 Tecan Trading Ag System und Vorrichtung zur Aufarbeitung biologischer Proben und zur Manipulation von Flüssigkeiten mit biologischen Proben.
KR20100101526A (ko) 2009-03-09 2010-09-17 삼성전자주식회사 스트로보 박막 화학 분석 장치 및 이를 이용한 분석 방법
EP2453219A4 (en) 2009-07-09 2016-06-15 Toppan Printing Co Ltd NUCLEIC ACID EXTRACTION KIT, NUCLEINE ACID EXTRACTION METHOD AND NUCLEAR ACID EXTRACTION DEVICE
CN201837588U (zh) 2009-09-09 2011-05-18 海利克斯公司 用于多个反应的光学系统
ES2913283T3 (es) * 2009-12-07 2022-06-01 Meso Scale Technologies Llc Cartuchos de ensayo
EP3000871A1 (en) 2009-12-18 2016-03-30 Novozymes, Inc. Methods for producing polypeptides in protease-deficient mutants of trichoderma
JP6058399B2 (ja) 2010-02-23 2017-01-11 レオニックス，インコーポレイテッド 自己完結的生物学的アッセイ装置、方法及び応用
US9248422B2 (en) 2010-02-23 2016-02-02 Luminex Corporation Apparatus and methods for integrated sample preparation, reaction and detection
KR101643196B1 (ko) * 2010-02-23 2016-07-27 루미넥스 코포레이션 일체화된 샘플 제조, 반응 및 검출을 위한 장치 및 방법
WO2011122066A1 (ja) 2010-03-31 2011-10-06 凸版印刷株式会社 多孔質フィルターカラム及びそれを用いた試薬カートリッジ並びに核酸精製キット
CA3016653C (en) 2010-04-16 2024-01-02 Opko Diagnostics, Llc Feedback control in microfluidic systems
WO2011149857A1 (en) 2010-05-24 2011-12-01 Abbott Diabetes Care Inc. Method and system for updating a medical device
GB201016014D0 (en) 2010-09-24 2010-11-10 Epistem Ltd Thermal cycler
US8454892B1 (en) 2010-10-15 2013-06-04 The United States Of America As Represented By The Secretary Of The Army Chemical agent detection system for fluid media
GB201018624D0 (en) 2010-11-04 2010-12-22 Epistem Ltd Reaction vessel
CN202379991U (zh) 2011-01-10 2012-08-15 伊鲁米那股份有限公司 核酸测序系统
CN106237444B (zh) 2011-04-08 2019-12-13 佳迈特股份有限公司 过滤针
US20140242612A1 (en) 2011-07-14 2014-08-28 Shuqi Wang System and method for integration of mobile device imaging with microchip elisa
JP2014530358A (ja) * 2011-09-25 2014-11-17 セラノス， インコーポレイテッド 多重分析のためのシステム及び方法
US10865440B2 (en) * 2011-10-21 2020-12-15 IntegenX, Inc. Sample preparation, processing and analysis systems
US8894946B2 (en) * 2011-10-21 2014-11-25 Integenx Inc. Sample preparation, processing and analysis systems
AU2013225728B2 (en) 2012-03-01 2018-07-26 Ortho-Clinical Diagnostics, Inc. Interactive test device and apparatus with timing mechanism
WO2013133725A1 (en) 2012-03-09 2013-09-12 Rawle Christopher Bruce Portable device for detecting molecule(s)
US20130331298A1 (en) * 2012-06-06 2013-12-12 Great Basin Scientific Analyzer and disposable cartridge for molecular in vitro diagnostics
AU2013280461A1 (en) 2012-06-25 2015-02-12 Grayl Inc. Filtration container assemblies and methods
US20150346097A1 (en) 2012-12-21 2015-12-03 Micronics, Inc. Portable fluorescence detection system and microassay cartridge
EP4480582A1 (en) 2013-01-18 2024-12-25 Biomeme, Inc. Analytic device
EP3533860A1 (en) 2013-05-31 2019-09-04 3i Diagnostics, Inc. Rapid microbial detection
GB2516666B (en) * 2013-07-29 2015-09-09 Atlas Genetics Ltd Fluidic cartridge for nucleic acid amplification and detection
EP3055407B1 (en) 2013-10-07 2022-01-12 Agdia Inc. Optical assembly for use in portable testing device for analyzing biological samples
CA2928843C (en) 2013-11-01 2021-11-23 Marc Dominic Dejohn Sample extraction and preparation device
US9535676B1 (en) 2014-04-04 2017-01-03 Seagate Technology Llc Remote feature activation
CN105092543A (zh) 2014-05-12 2015-11-25 绍兴安尼特微电子科技有限公司 一种便携式荧光定量pcr检测仪
MX383892B (es) 2014-08-08 2025-03-14 Quantum Si Inc Sistema optico y circuito integrado de valoración para sondear, detectar y analizar moleculas.
CN107209766B (zh) 2014-12-15 2021-04-06 卢米尼克斯股份有限公司 详细试验协议规范
GB2531616B (en) * 2015-02-02 2017-11-22 Atlas Genetics Ltd Instrument for performing a diagnostic test on a fluidic cartridge
US9921105B2 (en) 2015-02-05 2018-03-20 International Business Machines Corporation Mobile cellular spectroscopy
CN107548453B (zh) 2015-02-06 2021-03-23 生命技术公司 用于评价生物样本的系统和方法
US10497541B2 (en) * 2016-05-19 2019-12-03 Nedal Saleh Apparatus and method for programmable spatially selective nanoscale surface functionalization
WO2019055875A2 (en) 2017-09-15 2019-03-21 Biomeme, Inc. METHODS AND SYSTEMS FOR AUTOMATIC SAMPLE PROCESSING
JP7524061B2 (ja) 2017-12-15 2024-07-29 バイオミーム インコーポレイテッド サンプルを分析するためのポータブル装置及び方法
WO2019143812A1 (en) 2018-01-18 2019-07-25 Biomeme, Inc. Methods of assaying for the presence of microorganisms
CN113874708A (zh) 2019-03-21 2021-12-31 生米公司 多功能分析装置
CA3141275A1 (en) 2019-06-18 2020-12-24 Biomeme, Inc. Systems for sample analysis
CA3192080A1 (en) 2020-09-18 2022-03-24 Marc DEJOHN Portable devices and methods for analyzing samples

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20160069921A1 (en) * 2011-09-25 2016-03-10 Theranos, Inc. Systems and methods for multi-analysis
WO2017112911A1 (en) * 2015-12-22 2017-06-29 Canon U.S. Life Sciences, Inc Sample-to-answer system for microorganism detection featuring target enrichment, amplification and detection
WO2017139447A1 (en) * 2016-02-10 2017-08-17 Coyote Bioscience Usa Inc. Methods and systems for analyzing nucleic acids

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