JP7249287B2 - T細胞受容体シグナル伝達を阻害または調節することによって、t細胞枯渇を処置する方法 - Google Patents

T細胞受容体シグナル伝達を阻害または調節することによって、t細胞枯渇を処置する方法 Download PDF

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JP7249287B2
JP7249287B2 JP2019553214A JP2019553214A JP7249287B2 JP 7249287 B2 JP7249287 B2 JP 7249287B2 JP 2019553214 A JP2019553214 A JP 2019553214A JP 2019553214 A JP2019553214 A JP 2019553214A JP 7249287 B2 JP7249287 B2 JP 7249287B2
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リン,レイチェル
マッコール,クリスタル
ジェー. ワンドレス,トム
ウェバー,エヴァン
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Leland Stanford Junior University
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JP2019553214A 2017-03-31 2018-03-30 T細胞受容体シグナル伝達を阻害または調節することによって、t細胞枯渇を処置する方法 Active JP7249287B2 (ja)

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JP2022193805A JP7674328B2 (ja) 2017-03-31 2022-12-02 T細胞受容体シグナル伝達を阻害または調節することによって、t細胞枯渇を処置する方法
JP2024200383A JP2025026930A (ja) 2017-03-31 2024-11-18 T細胞受容体シグナル伝達を阻害または調節することによって、t細胞枯渇を処置する方法

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US201762479930P 2017-03-31 2017-03-31
US62/479,930 2017-03-31
PCT/US2018/025459 WO2018183888A2 (en) 2017-03-31 2018-03-30 Methods of treating t cell exhaustion by inhibiting or modulating t cell receptor signaling

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JP2019553214A Active JP7249287B2 (ja) 2017-03-31 2018-03-30 T細胞受容体シグナル伝達を阻害または調節することによって、t細胞枯渇を処置する方法
JP2019553220A Active JP7278961B2 (ja) 2017-03-31 2018-03-30 T細胞受容体のシグナル伝達を阻害するまたは調節することによってt細胞の疲弊を治療する方法
JP2022193805A Active JP7674328B2 (ja) 2017-03-31 2022-12-02 T細胞受容体シグナル伝達を阻害または調節することによって、t細胞枯渇を処置する方法
JP2023011257A Pending JP2023055805A (ja) 2017-03-31 2023-01-27 T細胞受容体のシグナル伝達を阻害するまたは調節することによってt細胞の疲弊を治療する方法
JP2024123405A Pending JP2024153812A (ja) 2017-03-31 2024-07-30 T細胞受容体のシグナル伝達を阻害するまたは調節することによってt細胞の疲弊を治療する方法
JP2024200383A Pending JP2025026930A (ja) 2017-03-31 2024-11-18 T細胞受容体シグナル伝達を阻害または調節することによって、t細胞枯渇を処置する方法

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JP2022193805A Active JP7674328B2 (ja) 2017-03-31 2022-12-02 T細胞受容体シグナル伝達を阻害または調節することによって、t細胞枯渇を処置する方法
JP2023011257A Pending JP2023055805A (ja) 2017-03-31 2023-01-27 T細胞受容体のシグナル伝達を阻害するまたは調節することによってt細胞の疲弊を治療する方法
JP2024123405A Pending JP2024153812A (ja) 2017-03-31 2024-07-30 T細胞受容体のシグナル伝達を阻害するまたは調節することによってt細胞の疲弊を治療する方法
JP2024200383A Pending JP2025026930A (ja) 2017-03-31 2024-11-18 T細胞受容体シグナル伝達を阻害または調節することによって、t細胞枯渇を処置する方法

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CN (3) CN118161496A (https=)
AU (3) AU2018243571B2 (https=)
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CN111699001A (zh) * 2017-12-07 2020-09-22 尤利乌斯·马克西米利安维尔茨堡大学 达沙替尼和其他酪氨酸激酶抑制剂对基因修饰的嵌合抗原受体t细胞的功能的控制和调节
US20210393628A1 (en) * 2018-10-30 2021-12-23 The Board Of Trustees Of The Leland Stanford Junior University Compositions and methods for modulating t cell exhaustion
WO2020097403A1 (en) * 2018-11-08 2020-05-14 Juno Therapeutics, Inc. Methods and combinations for treatment and t cell modulation
WO2020168122A1 (en) 2019-02-13 2020-08-20 Beam Therapeutics Inc. Modified immune cells having adenosine deaminase base editors for modifying a nucleobase in a target sequence
KR20210135255A (ko) * 2019-03-01 2021-11-12 내셔널 유니버시티 오브 싱가포르 조작된 면역 세포
CN110157680A (zh) * 2019-05-08 2019-08-23 浙江大学 提高嵌合抗原受体t细胞疗效和作用持久性的细胞培养方法
US20220275104A1 (en) * 2019-08-01 2022-09-01 Mie University Gd2 binding molecule
EP4034138A4 (en) 2019-09-27 2024-07-31 Beam Therapeutics, Inc. COMPOSITIONS AND METHODS FOR THE TREATMENT OF LIQUID CANCERS
GB202000934D0 (en) * 2020-01-22 2020-03-04 Ucl Business Ltd Engineered immune cells
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