JP7229467B2 - トランス－スプライシングＲＮＡ（ｔｓＲＮＡ） - Google Patents

トランス－スプライシングＲＮＡ（ｔｓＲＮＡ） Download PDF

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JP7229467B2
JP7229467B2 JP2018551404A JP2018551404A JP7229467B2 JP 7229467 B2 JP7229467 B2 JP 7229467B2 JP 2018551404 A JP2018551404 A JP 2018551404A JP 2018551404 A JP2018551404 A JP 2018551404A JP 7229467 B2 JP7229467 B2 JP 7229467B2
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trans
splicing
tsrna
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パツェル・フォルカー
ポダー・スシュミタ
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ナショナル ユニバーシティ オブ シンガポール
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JP2018551404A 2016-04-01 2017-03-31 トランス－スプライシングＲＮＡ（ｔｓＲＮＡ） Active JP7229467B2 (ja)

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GB201605586 2016-04-01
GB1605586.5 2016-04-01
PCT/SG2017/050183 WO2017171654A1 (en) 2016-04-01 2017-03-31 Trans-splicing rna (tsrna)

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US (2) US11517583B2 (https=)
EP (1) EP3436590A4 (https=)
JP (2) JP7229467B2 (https=)
CN (1) CN109642241B (https=)
AU (1) AU2017240703B2 (https=)
SG (1) SG11201808538QA (https=)
WO (1) WO2017171654A1 (https=)

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WO2021076656A1 (en) * 2019-10-15 2021-04-22 University Of Massachusetts Rna editor-enhanced rna trans-splicing
EP4100533A1 (en) * 2020-02-07 2022-12-14 University of Rochester Ribozyme-mediated rna assembly and expression
GB202102118D0 (en) 2021-02-15 2021-03-31 Cambridge Entpr Ltd RNA Trans-Splicing molecule
WO2022220968A1 (en) * 2021-04-15 2022-10-20 U1 Bio, Inc. High efficiency trans-splicing for replacement of targeted rna sequences in human cells
GB202108855D0 (en) 2021-06-21 2021-08-04 Cambridge Entpr Ltd Methods of eukaryotic gene expression
CN113584169B (zh) * 2021-07-28 2024-06-18 南京大学 一种与肝癌相关的血清tsRNA标志物、探针及其应用
AU2022337146A1 (en) * 2021-09-03 2024-03-14 Tacit Therapeutics, Inc. Rna editing via recruitment of spliceosome components
EP4466354A2 (en) * 2022-01-18 2024-11-27 National University of Singapore Trans-splicing rna (tsrna)
EP4522758A4 (en) 2022-05-13 2026-05-06 Ascidian Therapeutics Inc Abca4 trans-splicing molecules
WO2025085691A1 (en) * 2023-10-18 2025-04-24 Tacit Therapeutics, Inc. Trans-splicing nucleic acid molecules and methods of use
CN118813791A (zh) * 2024-09-14 2024-10-22 中国人民解放军总医院第二医学中心 用于诊断寒冷暴露致心肌损伤的生物标志物、试剂盒及应用

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JP2015534811A (ja) 2012-11-02 2015-12-07 バウアー，ヨハン 癌の治療に使用されるｒｎａトランススプライシング分子（ｒｔｍ）

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JP2015534811A (ja) 2012-11-02 2015-12-07 バウアー，ヨハン 癌の治療に使用されるｒｎａトランススプライシング分子（ｒｔｍ）

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SUSHMITA PODDAR，Chapter4 Results Trans-splicing RNA molecules for 3’and 5’exon labelling (EL) targeting alpha-fetoprotein (AFP), Chapter5 Results Selective killing of AFP positive cells triggered by trans-splicing，RNA trans-splicing for selective killing of virus-transduced or cancer cells，2016年01月，p.67-141
SUSHMITA PODDAR，Chapter4 Results Trans-splicing RNA molecules for 3’and 5’exon labelling (EL) targeting alpha-fetoprotein (AFP)，RNA trans-splicing for selective killing of virus-transduced or cancer cells，2016年01月，p.67-110

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US20240075051A1 (en) 2024-03-07
CN109642241B (zh) 2023-06-27
JP7570125B2 (ja) 2024-10-21
WO2017171654A1 (en) 2017-10-05
CN109642241A (zh) 2019-04-16
US11517583B2 (en) 2022-12-06
JP2019509756A (ja) 2019-04-11
SG11201808538QA (en) 2018-10-30
US20190111072A1 (en) 2019-04-18
JP2023055809A (ja) 2023-04-18
EP3436590A4 (en) 2019-12-04
AU2017240703B2 (en) 2020-05-21
EP3436590A1 (en) 2019-02-06
AU2017240703A1 (en) 2018-10-18

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