CN109642241B - 反式剪接RNA（tsRNA） - Google Patents

反式剪接RNA（tsRNA） Download PDF

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CN109642241B
CN109642241B CN201780034177.5A CN201780034177A CN109642241B CN 109642241 B CN109642241 B CN 109642241B CN 201780034177 A CN201780034177 A CN 201780034177A CN 109642241 B CN109642241 B CN 109642241B
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trans
splicing
rna
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cells
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CN109642241A (zh
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V·帕策尔
S·波达尔
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National University of Singapore
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CN201780034177.5A 2016-04-01 2017-03-31 反式剪接RNA（tsRNA） Active CN109642241B (zh)

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GB201605586 2016-04-01
GB1605586.5 2016-04-01
PCT/SG2017/050183 WO2017171654A1 (en) 2016-04-01 2017-03-31 Trans-splicing rna (tsrna)

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CN109642241B true CN109642241B (zh) 2023-06-27

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EP (1) EP3436590A4 (https=)
JP (2) JP7229467B2 (https=)
CN (1) CN109642241B (https=)
AU (1) AU2017240703B2 (https=)
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Families Citing this family (11)

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WO2021076656A1 (en) * 2019-10-15 2021-04-22 University Of Massachusetts Rna editor-enhanced rna trans-splicing
EP4100533A1 (en) * 2020-02-07 2022-12-14 University of Rochester Ribozyme-mediated rna assembly and expression
GB202102118D0 (en) 2021-02-15 2021-03-31 Cambridge Entpr Ltd RNA Trans-Splicing molecule
WO2022220968A1 (en) * 2021-04-15 2022-10-20 U1 Bio, Inc. High efficiency trans-splicing for replacement of targeted rna sequences in human cells
GB202108855D0 (en) 2021-06-21 2021-08-04 Cambridge Entpr Ltd Methods of eukaryotic gene expression
CN113584169B (zh) * 2021-07-28 2024-06-18 南京大学 一种与肝癌相关的血清tsRNA标志物、探针及其应用
AU2022337146A1 (en) * 2021-09-03 2024-03-14 Tacit Therapeutics, Inc. Rna editing via recruitment of spliceosome components
EP4466354A2 (en) * 2022-01-18 2024-11-27 National University of Singapore Trans-splicing rna (tsrna)
EP4522758A4 (en) 2022-05-13 2026-05-06 Ascidian Therapeutics Inc Abca4 trans-splicing molecules
WO2025085691A1 (en) * 2023-10-18 2025-04-24 Tacit Therapeutics, Inc. Trans-splicing nucleic acid molecules and methods of use
CN118813791A (zh) * 2024-09-14 2024-10-22 中国人民解放军总医院第二医学中心 用于诊断寒冷暴露致心肌损伤的生物标志物、试剂盒及应用

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WO2014068063A1 (en) * 2012-11-02 2014-05-08 Johann Bauer A rna trans-splicing molecule (rtm) for use in the treatment of cancer
EP2746388A2 (en) * 2011-08-19 2014-06-25 National Cancer Center Recombinant adenovirus comprising trans-splicing ribozyme and cancer-treating gene, and use thereof

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EP2746388A2 (en) * 2011-08-19 2014-06-25 National Cancer Center Recombinant adenovirus comprising trans-splicing ribozyme and cancer-treating gene, and use thereof
WO2014068063A1 (en) * 2012-11-02 2014-05-08 Johann Bauer A rna trans-splicing molecule (rtm) for use in the treatment of cancer

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US20240075051A1 (en) 2024-03-07
JP7570125B2 (ja) 2024-10-21
WO2017171654A1 (en) 2017-10-05
CN109642241A (zh) 2019-04-16
US11517583B2 (en) 2022-12-06
JP2019509756A (ja) 2019-04-11
SG11201808538QA (en) 2018-10-30
US20190111072A1 (en) 2019-04-18
JP2023055809A (ja) 2023-04-18
EP3436590A4 (en) 2019-12-04
AU2017240703B2 (en) 2020-05-21
EP3436590A1 (en) 2019-02-06
JP7229467B2 (ja) 2023-02-28
AU2017240703A1 (en) 2018-10-18

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