JP7224375B2 - ニコチン調製剤 - Google Patents

ニコチン調製剤 Download PDF

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Publication number
JP7224375B2
JP7224375B2 JP2020567039A JP2020567039A JP7224375B2 JP 7224375 B2 JP7224375 B2 JP 7224375B2 JP 2020567039 A JP2020567039 A JP 2020567039A JP 2020567039 A JP2020567039 A JP 2020567039A JP 7224375 B2 JP7224375 B2 JP 7224375B2
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Japan
Prior art keywords
acid
nicotine
oil
ester
pharmaceutical preparation
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Active
Application number
JP2020567039A
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English (en)
Japanese (ja)
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JP2021526147A (ja
JPWO2019229249A5 (https=
JP2021526147A5 (https=
Inventor
ノーラン クリストファー
カヴァナー ジョセフ
ラレー キーラン
オルーク ブライアン
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Yatzz Ltd
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Yatzz Ltd
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Publication of JPWO2019229249A5 publication Critical patent/JPWO2019229249A5/ja
Publication of JP2021526147A5 publication Critical patent/JP2021526147A5/ja
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Classifications

    • A—HUMAN NECESSITIES
    • A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
    • A24B—MANUFACTURE OR PREPARATION OF TOBACCO FOR SMOKING OR CHEWING; TOBACCO; SNUFF
    • A24B15/00—Chemical features or treatment of tobacco; Tobacco substitutes, e.g. in liquid form
    • A24B15/10—Chemical features of tobacco products or tobacco substitutes
    • A24B15/16—Chemical features of tobacco products or tobacco substitutes of tobacco substitutes
    • A24B15/167—Chemical features of tobacco products or tobacco substitutes of tobacco substitutes in liquid or vaporisable form, e.g. liquid compositions for electronic cigarettes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/465—Nicotine; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0078—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a nebulizer such as a jet nebulizer, ultrasonic nebulizer, e.g. in the form of aqueous drug solutions or dispersions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0085—Inhalators using ultrasonics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/06—Inhaling appliances shaped like cigars, cigarettes or pipes

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Otolaryngology (AREA)
  • Dispersion Chemistry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Manufacture Of Tobacco Products (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
JP2020567039A 2018-06-01 2019-05-31 ニコチン調製剤 Active JP7224375B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP18175640.4A EP3574902A1 (en) 2018-06-01 2018-06-01 Nicotine formulation and mode of delivery
EP18175640.4 2018-06-01
PCT/EP2019/064212 WO2019229249A1 (en) 2018-06-01 2019-05-31 Nicotine formulation

Publications (4)

Publication Number Publication Date
JP2021526147A JP2021526147A (ja) 2021-09-30
JPWO2019229249A5 JPWO2019229249A5 (https=) 2022-05-02
JP2021526147A5 JP2021526147A5 (https=) 2022-05-02
JP7224375B2 true JP7224375B2 (ja) 2023-02-17

Family

ID=62528283

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2020567039A Active JP7224375B2 (ja) 2018-06-01 2019-05-31 ニコチン調製剤

Country Status (13)

Country Link
US (2) US11833145B2 (https=)
EP (3) EP3574902A1 (https=)
JP (1) JP7224375B2 (https=)
CN (1) CN112218637A (https=)
AU (2) AU2019276357B2 (https=)
BR (1) BR112020024088B1 (https=)
ES (1) ES2883799T3 (https=)
MA (2) MA50205B1 (https=)
MX (1) MX390509B (https=)
PL (1) PL3684362T3 (https=)
SG (1) SG11202011761XA (https=)
WO (1) WO2019229249A1 (https=)
ZA (1) ZA202007717B (https=)

Families Citing this family (48)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3574902A1 (en) * 2018-06-01 2019-12-04 Yatzz Limited Nicotine formulation and mode of delivery
GB201817865D0 (en) * 2018-11-01 2018-12-19 Nicoventures Trading Ltd Aerosolisable formulation
GB201817868D0 (en) * 2018-11-01 2018-12-19 Nicoventures Trading Ltd Aerosolised formulation
GB201817867D0 (en) * 2018-11-01 2018-12-19 Nicoventures Trading Ltd Aerosolisable formulation
GB201817859D0 (en) * 2018-11-01 2018-12-19 Nicoventures Trading Ltd Aerosolisable formulation
GB201817863D0 (en) * 2018-11-01 2018-12-19 Nicoventures Trading Ltd Aerosolisable formulation
GB201817860D0 (en) 2018-11-01 2018-12-19 Nicoventures Trading Ltd Aerosolised formulation
BR112021010222A2 (pt) * 2018-12-31 2021-08-24 Philip Morris Products S.A. Formulação de nicotina líquida compreendendo solventes imiscíveis em água
PL3905908T3 (pl) 2019-06-20 2025-03-24 Shaheen Innovations Holding Limited Ultradźwiękowe urządzenie rozpylające do użytku osobistego
FR3102041B1 (fr) * 2019-10-22 2025-02-14 Aroma Sens Edulcorant pour liquides de cigarette électronique
US12233207B2 (en) 2019-12-15 2025-02-25 Shaheen Innovations Holding Limited Mist inhaler devices
US11730193B2 (en) 2019-12-15 2023-08-22 Shaheen Innovations Holding Limited Hookah device
ES3014051T3 (en) 2019-12-15 2025-04-16 Shaheen Innovations Holding Ltd Mist inhaler devices
US11666713B2 (en) 2019-12-15 2023-06-06 Shaheen Innovations Holding Limited Mist inhaler devices
JP7583061B2 (ja) 2019-12-15 2024-11-13 シャヒーン イノベーションズ ホールディング リミテッド 超音波ミスト吸入器
US12213516B2 (en) 2019-12-15 2025-02-04 Shaheen Innovations Holding Limited Ultrasonic mist inhaler
US12121056B2 (en) 2019-12-15 2024-10-22 Shaheen Innovations Holding Limited Hookah device
PL4292632T3 (pl) 2019-12-15 2025-11-24 Shaheen Innovations Holding Limited Ultradźwiękowy inhalator mgiełki
US11589610B2 (en) 2019-12-15 2023-02-28 Shaheen Innovations Holding Limited Nicotine delivery device having a mist generator device and a driver device
US11911559B2 (en) 2019-12-15 2024-02-27 Shaheen Innovations Holding Limited Ultrasonic mist inhaler
US11944120B2 (en) 2019-12-15 2024-04-02 Shaheen Innovations Holding Limited Ultrasonic mist inhaler with capillary retainer
US12201144B2 (en) 2019-12-15 2025-01-21 Shaheen Innovations Holding Limited Hookah device
US11730191B2 (en) 2019-12-15 2023-08-22 Shaheen Innovations Holding Limited Hookah device
US12538944B2 (en) 2019-12-15 2026-02-03 Shaheen Innovations Holding Limited Nicotine delivery device with identification arrangement
BR112022011449A2 (pt) * 2019-12-18 2022-08-30 Philip Morris Products Sa Formulação para uso em um sistema gerador de aerossol
JP7609561B2 (ja) * 2020-02-05 2025-01-07 日本たばこ産業株式会社 液体加熱式の加熱型香味吸引器用の液体組成物
IL296737A (en) 2020-03-27 2022-11-01 Mcneil Ab A cartridge with nicotine
MA57567B1 (fr) * 2020-04-06 2022-09-30 Shaheen Innovations Holding Ltd Dispositifs d'inhalateur de brouillard
CN111802686A (zh) * 2020-07-27 2020-10-23 湖北中烟工业有限责任公司 含脂肪酸、植物油的雾化剂以及加热不燃烧卷烟
CN111855866A (zh) * 2020-08-25 2020-10-30 甘肃烟草工业有限责任公司 一种快速测定烟用添加剂中甲醛的方法
IL303786B2 (en) * 2020-12-15 2024-07-01 Shaheen Innovations Holding Ltd Mist inhaler devices
CN114947174A (zh) * 2021-02-25 2022-08-30 深圳市合元科技有限公司 气溶胶形成基质以及气溶胶生成系统
CN113197330A (zh) * 2021-04-28 2021-08-03 深圳市博睿生物科技有限公司 一种电子烟新型甜味剂及制备方法及应用
IL283002A (en) * 2021-05-06 2022-12-01 Nicogen Ltd Nicotine formulations and aerosols
CN113912585B (zh) * 2021-11-09 2023-02-24 深圳萨特瓦生物科技有限公司 复合尼古丁盐及其制备方法与应用、电子烟油及电子烟
US20230188901A1 (en) 2021-12-15 2023-06-15 Shaheen Innovations Holding Limited Apparatus for transmitting ultrasonic waves
CN116326810B (zh) * 2021-12-22 2026-03-17 深圳市富淼生物科技有限公司 水基雾化剂、指定用途水基雾化物、雾化弹以及雾化装置
CN114886145A (zh) * 2022-06-10 2022-08-12 广州市维城生物科技有限公司 一种水基烟碱电子烟雾化液及其制备方法
KR20240012197A (ko) * 2022-07-20 2024-01-29 주식회사 케이티앤지 표면파 아토마이저에 사용하기 위한 액상형 흡입제형, 이를 포함하는 카트리지 및 에어로졸 생성장치
KR102872477B1 (ko) * 2022-08-10 2025-10-20 주식회사 케이티앤지 니코틴 흡입성 조성물 및 이를 포함하는 에어로졸 발생 장치 및 시스템
CN116019250B (zh) * 2022-12-22 2025-02-14 东莞市吉纯生物技术有限公司 基于酸性电解水的雾化液、制备方法和酸性电解水制备方法
WO2024138377A1 (zh) * 2022-12-27 2024-07-04 思摩尔国际控股有限公司 一种雾化液、雾化器及电子雾化装置
WO2024161313A1 (en) * 2023-01-31 2024-08-08 Rai Strategic Holdings, Inc. Stabilized aerosol precursor formulations
CN118787123A (zh) * 2023-04-14 2024-10-18 思摩尔国际控股有限公司 一种水基电子烟雾化制剂及其制备方法和应用
PL446676A1 (pl) * 2023-11-08 2025-05-12 Dmitrii Shesternenko Kompozycja liquidu do e-papierosa oraz e-papieros zawierający taką kompozycję
FR3159394A1 (fr) * 2024-02-19 2025-08-22 Swm Holdco Luxembourg Feuille de papier comprenant un extrait de plante et de la nicotine stabilisée
CN117898466B (zh) * 2024-02-29 2024-09-24 深圳市艾斯摩迪斯科技有限公司 一种复合尼古丁盐的制备方法及其应用
CN120923467A (zh) * 2025-07-31 2025-11-11 深圳曼华生物科技有限公司 尼古丁盐的制备方法、检测方法、制备的尼古丁盐及应用

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2005533770A (ja) 2002-06-03 2005-11-10 ファイザー ヘルス アクティエボラーグ 肺投与のための緩衝化液状ニコチン組成物
JP2016520061A (ja) 2013-05-06 2016-07-11 パックス ラブズ， インク． エアロゾル装置用のニコチン塩製剤とその方法
DE102015117811A1 (de) 2015-10-20 2017-04-20 Chv Pharma Gmbh & Co. Kg Inhalator sowie wirkstoffhaltige Zubereitung für einen Inhalator

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GB0712308D0 (en) * 2007-06-25 2007-08-01 Kind Group Ltd An inhalable composition
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EP3574902A1 (en) * 2018-06-01 2019-12-04 Yatzz Limited Nicotine formulation and mode of delivery

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2005533770A (ja) 2002-06-03 2005-11-10 ファイザー ヘルス アクティエボラーグ 肺投与のための緩衝化液状ニコチン組成物
JP2016520061A (ja) 2013-05-06 2016-07-11 パックス ラブズ， インク． エアロゾル装置用のニコチン塩製剤とその方法
DE102015117811A1 (de) 2015-10-20 2017-04-20 Chv Pharma Gmbh & Co. Kg Inhalator sowie wirkstoffhaltige Zubereitung für einen Inhalator

Also Published As

Publication number Publication date
MX2020012810A (es) 2022-03-08
BR112020024088A2 (pt) 2021-02-17
US20210196700A1 (en) 2021-07-01
AU2019276357A1 (en) 2020-11-26
JP2021526147A (ja) 2021-09-30
US11833145B2 (en) 2023-12-05
EP3909581A1 (en) 2021-11-17
ZA202007717B (en) 2026-03-25
MX390509B (es) 2025-03-11
CN112218637A (zh) 2021-01-12
EP3684362B1 (en) 2021-06-23
MA50205A (fr) 2020-07-29
CA3099940A1 (en) 2019-12-05
MA50205B1 (fr) 2021-09-30
AU2023202855B2 (en) 2024-08-22
PL3684362T3 (pl) 2021-12-20
BR112020024088B1 (pt) 2022-10-11
EP3684362A1 (en) 2020-07-29
SG11202011761XA (en) 2020-12-30
US20240050424A1 (en) 2024-02-15
MA54714A (fr) 2021-11-17
AU2023202855A1 (en) 2023-05-25
ES2883799T3 (es) 2021-12-09
WO2019229249A1 (en) 2019-12-05
AU2019276357B2 (en) 2023-04-20
NZ769793A (en) 2024-05-31
EP3574902A1 (en) 2019-12-04

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