JP7141625B1 - マイクロニードルパッチ及びマイクロニードル構造体 - Google Patents

マイクロニードルパッチ及びマイクロニードル構造体 Download PDF

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Publication number
JP7141625B1
JP7141625B1 JP2021152537A JP2021152537A JP7141625B1 JP 7141625 B1 JP7141625 B1 JP 7141625B1 JP 2021152537 A JP2021152537 A JP 2021152537A JP 2021152537 A JP2021152537 A JP 2021152537A JP 7141625 B1 JP7141625 B1 JP 7141625B1
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Japan
Prior art keywords
needle
base material
functional member
absorbent material
substrate
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JP2021152537A
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English (en)
Japanese (ja)
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JP2023044484A (ja
Inventor
洋佑 高麗
範ジュン 金
チョンホ 朴
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Lintec Corp
University of Tokyo NUC
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Lintec Corp
University of Tokyo NUC
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Priority to JP2021152537A priority Critical patent/JP7141625B1/ja
Application filed by Lintec Corp, University of Tokyo NUC filed Critical Lintec Corp
Priority to JP2023548137A priority patent/JPWO2023042525A1/ja
Priority to CN202280059330.0A priority patent/CN117897199A/zh
Priority to PCT/JP2022/026226 priority patent/WO2023042525A1/ja
Priority to KR1020247004905A priority patent/KR20240056491A/ko
Priority to TW111124589A priority patent/TW202312938A/zh
Priority to DE112022004458.6T priority patent/DE112022004458T5/de
Priority to US18/692,290 priority patent/US20240424271A1/en
Application granted granted Critical
Publication of JP7141625B1 publication Critical patent/JP7141625B1/ja
Publication of JP2023044484A publication Critical patent/JP2023044484A/ja
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
    • A61B5/14503—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue invasive, e.g. introduced into the body by a catheter or needle or using implanted sensors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
    • A61B5/14507—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue specially adapted for measuring characteristics of body fluids other than blood
    • A61B5/1451—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue specially adapted for measuring characteristics of body fluids other than blood for interstitial fluid
    • A61B5/14514—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue specially adapted for measuring characteristics of body fluids other than blood for interstitial fluid using means for aiding extraction of interstitial fluid, e.g. microneedles or suction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
    • A61B5/14532—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue for measuring glucose, e.g. by tissue impedance measurement
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
    • A61B5/1468—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue using chemical or electrochemical methods, e.g. by polarographic means
    • A61B5/1473—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue using chemical or electrochemical methods, e.g. by polarographic means invasive, e.g. introduced into the body by a catheter
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/150007—Details
    • A61B5/150015—Source of blood
    • A61B5/150022—Source of blood for capillary blood or interstitial fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/150969—Low-profile devices which resemble patches or plasters, e.g. also allowing collection of blood samples for testing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/150977—Arrays of piercing elements for simultaneous piercing
    • A61B5/150984—Microneedles or microblades
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/157—Devices characterised by integrated means for measuring characteristics of blood
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/48—Other medical applications
    • A61B5/4836—Diagnosis combined with treatment in closed-loop systems or methods
    • A61B5/4839—Diagnosis combined with treatment in closed-loop systems or methods combined with drug delivery
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
    • A61B5/6801—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be attached to or worn on the body surface
    • A61B5/683—Means for maintaining contact with the body
    • A61B5/6832—Means for maintaining contact with the body using adhesives
    • A61B5/6833—Adhesive patches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
    • A61B5/6846—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive
    • A61B5/6847—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive mounted on an invasive device
    • A61B5/685—Microneedles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B2562/00—Details of sensors; Constructional details of sensor housings or probes; Accessories for sensors
    • A61B2562/12—Manufacturing methods specially adapted for producing sensors for in-vivo measurements
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0023—Drug applicators using microneedles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0053—Methods for producing microneedles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0061—Methods for using microneedles

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Public Health (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pathology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Surgery (AREA)
  • Hematology (AREA)
  • Optics & Photonics (AREA)
  • Dermatology (AREA)
  • Anesthesiology (AREA)
  • Emergency Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Media Introduction/Drainage Providing Device (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
  • Medicinal Preparation (AREA)
JP2021152537A 2021-09-17 2021-09-17 マイクロニードルパッチ及びマイクロニードル構造体 Active JP7141625B1 (ja)

Priority Applications (8)

Application Number Priority Date Filing Date Title
JP2021152537A JP7141625B1 (ja) 2021-09-17 2021-09-17 マイクロニードルパッチ及びマイクロニードル構造体
CN202280059330.0A CN117897199A (zh) 2021-09-17 2022-06-30 微针贴片
PCT/JP2022/026226 WO2023042525A1 (ja) 2021-09-17 2022-06-30 マイクロニードルパッチ
KR1020247004905A KR20240056491A (ko) 2021-09-17 2022-06-30 마이크로 니들 패치
JP2023548137A JPWO2023042525A1 (https=) 2021-09-17 2022-06-30
TW111124589A TW202312938A (zh) 2021-09-17 2022-06-30 微針貼片
DE112022004458.6T DE112022004458T5 (de) 2021-09-17 2022-06-30 Mikronadelpflaster
US18/692,290 US20240424271A1 (en) 2021-09-17 2022-06-30 Microneedle patch

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2021152537A JP7141625B1 (ja) 2021-09-17 2021-09-17 マイクロニードルパッチ及びマイクロニードル構造体

Publications (2)

Publication Number Publication Date
JP7141625B1 true JP7141625B1 (ja) 2022-09-26
JP2023044484A JP2023044484A (ja) 2023-03-30

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JP2021152537A Active JP7141625B1 (ja) 2021-09-17 2021-09-17 マイクロニードルパッチ及びマイクロニードル構造体
JP2023548137A Pending JPWO2023042525A1 (https=) 2021-09-17 2022-06-30

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JP2023548137A Pending JPWO2023042525A1 (https=) 2021-09-17 2022-06-30

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US (1) US20240424271A1 (https=)
JP (2) JP7141625B1 (https=)
KR (1) KR20240056491A (https=)
CN (1) CN117897199A (https=)
DE (1) DE112022004458T5 (https=)
TW (1) TW202312938A (https=)
WO (1) WO2023042525A1 (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20250064349A1 (en) * 2023-08-25 2025-02-27 General Electric Company Microneedle-integrated interstitial fluid biomarker sensor systems and methods thereof

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2025005050A1 (ja) * 2023-06-30 2025-01-02 リンテック株式会社 マイクロニードル構造体及びマイクロニードルパッチ
CN121794573A (zh) * 2023-09-26 2026-04-03 凸版控股株式会社 检查设备及检查方法
WO2025105446A1 (ja) * 2023-11-14 2025-05-22 リンテック株式会社 マイクロニードルパッチ及び分析方法
WO2025105444A1 (ja) * 2023-11-14 2025-05-22 リンテック株式会社 マイクロニードル構造体、マイクロニードルパッチ及びマイクロニードル構造体の製造方法
WO2025105296A1 (ja) * 2023-11-14 2025-05-22 リンテック株式会社 マイクロニードル構造体及びその製造方法
WO2025182934A1 (ja) * 2024-02-26 2025-09-04 国立大学法人 東京大学 多孔質マイクロニードルを備えるマイクロニードルパッチ、及び当該マイクロニードルパッチを製造する方法
WO2026071014A1 (ja) * 2024-09-30 2026-04-02 リンテック株式会社 マイクロニードル構造体及びその製造方法
WO2026071015A1 (ja) * 2024-09-30 2026-04-02 リンテック株式会社 マイクロニードル構造体の製造方法及びマイクロニードル構造体
KR102883072B1 (ko) 2025-07-04 2025-11-06 원종표 마이크로 니들형 두피자극기

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2002532165A (ja) 1998-12-18 2002-10-02 メドトロニック ミニメド インコーポレイテッド 医療装置と共に使われる、微小突刺し部材を備える挿入セット及びそのような挿入セットの使用方法
JP2003038467A (ja) 2001-06-12 2003-02-12 Lifescan Inc 生物流体サンプリングおよび分析物測定の装置および方法
JP2005514179A (ja) 2002-01-15 2005-05-19 スリーエム イノベイティブ プロパティズ カンパニー マイクロニードル装置および製造方法
JP2012509138A (ja) 2008-11-20 2012-04-19 アーカル・メディカル，インコーポレーテッド 持続的分析物モニタリングのためのデバイス、システム、方法、およびツール
WO2019176126A1 (ja) 2018-03-16 2019-09-19 国立大学法人東京大学 検査チップおよび検査装置

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2017000724A (ja) * 2015-06-05 2017-01-05 国立大学法人東北大学 マイクロニードル及びマイクロアレイ並びにその製造方法
JP6767695B2 (ja) 2018-03-29 2020-10-14 パナソニックＩｐマネジメント株式会社 組成物、近赤外光電変換素子および撮像装置

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2002532165A (ja) 1998-12-18 2002-10-02 メドトロニック ミニメド インコーポレイテッド 医療装置と共に使われる、微小突刺し部材を備える挿入セット及びそのような挿入セットの使用方法
JP2003038467A (ja) 2001-06-12 2003-02-12 Lifescan Inc 生物流体サンプリングおよび分析物測定の装置および方法
JP2005514179A (ja) 2002-01-15 2005-05-19 スリーエム イノベイティブ プロパティズ カンパニー マイクロニードル装置および製造方法
JP2012509138A (ja) 2008-11-20 2012-04-19 アーカル・メディカル，インコーポレーテッド 持続的分析物モニタリングのためのデバイス、システム、方法、およびツール
WO2019176126A1 (ja) 2018-03-16 2019-09-19 国立大学法人東京大学 検査チップおよび検査装置

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20250064349A1 (en) * 2023-08-25 2025-02-27 General Electric Company Microneedle-integrated interstitial fluid biomarker sensor systems and methods thereof

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Publication number Publication date
JPWO2023042525A1 (https=) 2023-03-23
DE112022004458T5 (de) 2024-08-22
JP2023044484A (ja) 2023-03-30
TW202312938A (zh) 2023-04-01
CN117897199A (zh) 2024-04-16
KR20240056491A (ko) 2024-04-30
US20240424271A1 (en) 2024-12-26
WO2023042525A1 (ja) 2023-03-23

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