JP7133468B2 - マイクロrna認識エレメントを含むcmvベクター - Google Patents
マイクロrna認識エレメントを含むcmvベクター Download PDFInfo
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- JP7133468B2 JP7133468B2 JP2018526190A JP2018526190A JP7133468B2 JP 7133468 B2 JP7133468 B2 JP 7133468B2 JP 2018526190 A JP2018526190 A JP 2018526190A JP 2018526190 A JP2018526190 A JP 2018526190A JP 7133468 B2 JP7133468 B2 JP 7133468B2
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- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
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- C12N2710/16011—Herpesviridae
- C12N2710/16111—Cytomegalovirus, e.g. human herpesvirus 5
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- C12N2710/00011—Details
- C12N2710/16011—Herpesviridae
- C12N2710/16111—Cytomegalovirus, e.g. human herpesvirus 5
- C12N2710/16141—Use of virus, viral particle or viral elements as a vector
- C12N2710/16143—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
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- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/16011—Herpesviridae
- C12N2710/16111—Cytomegalovirus, e.g. human herpesvirus 5
- C12N2710/16161—Methods of inactivation or attenuation
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- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/15011—Lentivirus, not HIV, e.g. FIV, SIV
- C12N2740/15034—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
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- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
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- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
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- Animal Behavior & Ethology (AREA)
- Organic Chemistry (AREA)
- Virology (AREA)
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- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
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- Genetics & Genomics (AREA)
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- General Engineering & Computer Science (AREA)
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- Biochemistry (AREA)
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- Hematology (AREA)
- AIDS & HIV (AREA)
- Gastroenterology & Hepatology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2022135565A JP2022174123A (ja) | 2015-11-20 | 2022-08-29 | マイクロrna認識エレメントを含むcmvベクター |
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562258393P | 2015-11-20 | 2015-11-20 | |
| US62/258,393 | 2015-11-20 | ||
| US201662365259P | 2016-07-21 | 2016-07-21 | |
| US62/365,259 | 2016-07-21 | ||
| PCT/US2016/062973 WO2017087921A1 (en) | 2015-11-20 | 2016-11-20 | Cmv vectors comprising microrna recognition elements |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022135565A Division JP2022174123A (ja) | 2015-11-20 | 2022-08-29 | マイクロrna認識エレメントを含むcmvベクター |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2019502371A JP2019502371A (ja) | 2019-01-31 |
| JP2019502371A5 JP2019502371A5 (cg-RX-API-DMAC7.html) | 2019-12-26 |
| JP7133468B2 true JP7133468B2 (ja) | 2022-09-08 |
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ID=58719315
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018526190A Active JP7133468B2 (ja) | 2015-11-20 | 2016-11-20 | マイクロrna認識エレメントを含むcmvベクター |
| JP2022135565A Pending JP2022174123A (ja) | 2015-11-20 | 2022-08-29 | マイクロrna認識エレメントを含むcmvベクター |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022135565A Pending JP2022174123A (ja) | 2015-11-20 | 2022-08-29 | マイクロrna認識エレメントを含むcmvベクター |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US10688164B2 (cg-RX-API-DMAC7.html) |
| EP (1) | EP3377636A4 (cg-RX-API-DMAC7.html) |
| JP (2) | JP7133468B2 (cg-RX-API-DMAC7.html) |
| CN (2) | CN116926128A (cg-RX-API-DMAC7.html) |
| AU (1) | AU2016355468B2 (cg-RX-API-DMAC7.html) |
| CA (1) | CA3005136A1 (cg-RX-API-DMAC7.html) |
| MA (1) | MA43285A (cg-RX-API-DMAC7.html) |
| WO (1) | WO2017087921A1 (cg-RX-API-DMAC7.html) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SI2772265T1 (en) | 2010-05-14 | 2018-06-29 | Oregon Health & Science University | HCMV AND RHCMV RECOMBINANT VECTORS AND THEIR APPLICATIONS |
| SI2691530T1 (en) | 2011-06-10 | 2018-08-31 | Oregon Health & Science University | Cmv glycoproteins and recombinant vectors |
| ES2696703T3 (es) | 2013-03-05 | 2019-01-17 | Univ Oregon Health & Science | Vectores de citomegalovirus que permiten el control del direccionamiento de los linfocitos T |
| CA3113595A1 (en) | 2014-07-16 | 2016-01-21 | Oregon Health & Science University | Human cytomegalovirus comprising exogenous antigens |
| KR20170136512A (ko) | 2015-02-10 | 2017-12-11 | 오레곤 헬스 앤드 사이언스 유니버시티 | 넌-캐노니컬 cd8+ t 세포 반응 생성에 유용한 방법 및 조성물 |
| CA3005136A1 (en) | 2015-11-20 | 2017-05-26 | Oregon Health & Science University | Cmv vectors comprising microrna recognition elements |
| AU2017280065B2 (en) | 2016-06-22 | 2021-07-01 | International Aids Vaccine Initiative, Inc. | Recombinant cytomegalovirus vectors as vaccines for tuberculosis |
| CA3040303A1 (en) | 2016-10-18 | 2018-04-26 | Oregon Health & Science University | Cytomegalovirus vectors eliciting t cells restricted by major histocompatibility complex e molecules |
| GB201714430D0 (en) * | 2017-09-07 | 2017-10-25 | Micol Romain | Compositions and processes for targeted delivery and expression and modulation of therapeutic components in tissue |
| WO2019079155A1 (en) | 2017-10-17 | 2019-04-25 | International Aids Vaccine Initiative, Inc. | CASSETTES OF ANTIGENS OF TUBERCULOSIS |
| WO2020247859A2 (en) * | 2019-06-07 | 2020-12-10 | Oregon Health & Science University | Tumor-associated antigen-specific t cell responses |
| US20220307054A1 (en) | 2019-08-20 | 2022-09-29 | Oregon Health & Science University | Modulation of t cell responses by ul18 of human cytomegalovirus |
| WO2021168405A1 (en) | 2020-02-21 | 2021-08-26 | Combined Therapeutics, Inc. | Compositions and methods for organ-protective expression and modulation of coding ribonucleic acids |
| IL310663A (en) | 2021-08-31 | 2024-04-01 | Vir Biotechnology Inc | Recombinant hcmv vectors and uses thereof |
| EP4396208A1 (en) | 2021-08-31 | 2024-07-10 | VIR Biotechnology, Inc. | Tuberculosis vaccines |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20130136768A1 (en) | 2010-05-14 | 2013-05-30 | Oregon Health & Science University | Recombinant HCMV and RHCMV vectors and uses thereof |
| WO2014089148A1 (en) | 2012-12-05 | 2014-06-12 | Qualcomm Incorporated | Successive interference cancellation (sic) ordering algorithms for improved multiple-input multiple-output (mimo) performance |
| WO2014138209A1 (en) | 2013-03-05 | 2014-09-12 | Oregon Health & Science University | Cytomegalovirus vectors enabling control of t cell targeting |
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| US5168062A (en) | 1985-01-30 | 1992-12-01 | University Of Iowa Research Foundation | Transfer vectors and microorganisms containing human cytomegalovirus immediate-early promoter-regulatory DNA sequence |
| DE3853139T2 (de) | 1987-06-26 | 1995-06-14 | Syntro Corp | Rekombinanter, fremde gene enthaltender menschlicher cytomegalovirus und seine verwendung. |
| US5273876A (en) | 1987-06-26 | 1993-12-28 | Syntro Corporation | Recombinant human cytomegalovirus containing foreign gene |
| JP2708960B2 (ja) * | 1990-08-16 | 1998-02-04 | アイシス・ファーマシューティカルス・インコーポレーテッド | サイトメガウイルス感染の作用を変調するオリゴヌクレオチド |
| SG49046A1 (en) | 1991-07-05 | 1998-05-18 | American Cyanamid Co | Method for identifying non-essential genes of the human cytomegalovirus genome and for screening for inhibitors of human cytomegaloverirus |
| WO1995003399A2 (en) | 1993-07-19 | 1995-02-02 | Cantab Pharmaceuticals Research Limited | Production method for preparation of disabled viruses |
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| US5846806A (en) | 1994-07-29 | 1998-12-08 | American Cyanamid Company | Identification of a human cytomegalovirus gene region involved in down-regulation of MHC class I heavy chain expression |
| AU711121B2 (en) | 1995-02-21 | 1999-10-07 | Cantab Pharmaceuticals Research Limited | Viral preparations, vectors, immunogens, and vaccines |
| JPH11503024A (ja) | 1995-04-04 | 1999-03-23 | セル・ジェネシス・インコーポレイテッド | 細胞表面のクラスi mhcタンパク質の低レベルを有する遺伝子学的に修飾された細胞の移植 |
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| US20030138454A1 (en) | 1997-06-09 | 2003-07-24 | Oxxon Pharmaccines, Ltd. | Vaccination method |
| DE19733364A1 (de) | 1997-08-01 | 1999-02-04 | Koszinowski Ulrich H Prof | Verfahren zur Klonierung eines großen Virusgenoms |
| WO1999007869A1 (en) | 1997-08-05 | 1999-02-18 | University Of Florida | Live recombinant vaccine comprising inefficiently or non-replicating virus |
| US6884785B2 (en) * | 1999-06-17 | 2005-04-26 | The Scripps Research Institute | Compositions and methods for the treatment or prevention of autoimmune diabetes |
| US7204990B1 (en) | 2000-11-28 | 2007-04-17 | Medimmune Vaccines, Inc. | Attenuation of cytomegalovirus virulence |
| WO2002062296A2 (en) | 2001-02-02 | 2002-08-15 | Chemocentryx, Inc. | Methods and compositions useful for stimulating an immune response |
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| US20030118568A1 (en) | 2001-12-18 | 2003-06-26 | Board Of Trustees Of The University Of Arkansas | Viral stealth technology to prevent T cell-mediated rejection of xenografts |
| JP2005523942A (ja) | 2002-04-30 | 2005-08-11 | アヴィオル セラピューティクス インコーポレイテッド | 免疫療法のためのアデノウイルスベクター |
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| CN116926128A (zh) | 2023-10-24 |
| EP3377636A1 (en) | 2018-09-26 |
| EP3377636A4 (en) | 2019-11-06 |
| JP2019502371A (ja) | 2019-01-31 |
| WO2017087921A1 (en) | 2017-05-26 |
| US20170143809A1 (en) | 2017-05-25 |
| US10688164B2 (en) | 2020-06-23 |
| AU2016355468B2 (en) | 2022-12-15 |
| AU2016355468A1 (en) | 2018-05-31 |
| JP2022174123A (ja) | 2022-11-22 |
| US20200368333A1 (en) | 2020-11-26 |
| MA43285A (fr) | 2018-09-26 |
| CN108474003A (zh) | 2018-08-31 |
| CA3005136A1 (en) | 2017-05-26 |
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