MA43285A - Vecteurs cmv comprenant des éléments de reconnaissance des microarn - Google Patents

Vecteurs cmv comprenant des éléments de reconnaissance des microarn

Info

Publication number
MA43285A
MA43285A MA043285A MA43285A MA43285A MA 43285 A MA43285 A MA 43285A MA 043285 A MA043285 A MA 043285A MA 43285 A MA43285 A MA 43285A MA 43285 A MA43285 A MA 43285A
Authority
MA
Morocco
Prior art keywords
recognition elements
vectors including
cmv vectors
including microrna
microrna recognition
Prior art date
Application number
MA043285A
Other languages
English (en)
Inventor
Klaus Frueh
Meaghan H Hancock
Scott Hansen
Jay Nelson
Louis Picker
Original Assignee
Univ Oregon Health & Science
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Oregon Health & Science filed Critical Univ Oregon Health & Science
Publication of MA43285A publication Critical patent/MA43285A/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/0005—Vertebrate antigens
    • A61K39/0011—Cancer antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A61P31/06—Antibacterial agents for tuberculosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A61P31/22—Antivirals for DNA viruses for herpes viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A61P33/06—Antimalarials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86—Viral vectors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525—Virus
    • A61K2039/5256—Virus expressing foreign proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/55—Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
    • A61K2039/552—Veterinary vaccine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/57—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
    • A61K2039/572—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2 cytotoxic response
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/16011—Herpesviridae
    • C12N2710/16111—Cytomegalovirus, e.g. human herpesvirus 5
    • C12N2710/16134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/16011—Herpesviridae
    • C12N2710/16111—Cytomegalovirus, e.g. human herpesvirus 5
    • C12N2710/16141—Use of virus, viral particle or viral elements as a vector
    • C12N2710/16143—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/16011—Herpesviridae
    • C12N2710/16111—Cytomegalovirus, e.g. human herpesvirus 5
    • C12N2710/16161—Methods of inactivation or attenuation
    • C12N2710/16162—Methods of inactivation or attenuation by genetic engineering
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/15011—Lentivirus, not HIV, e.g. FIV, SIV
    • C12N2740/15034—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Organic Chemistry (AREA)
  • Virology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Oncology (AREA)
  • Genetics & Genomics (AREA)
  • Communicable Diseases (AREA)
  • Immunology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Biochemistry (AREA)
  • Plant Pathology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Pulmonology (AREA)
  • Hematology (AREA)
  • AIDS & HIV (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
MA043285A 2015-11-20 2016-11-20 Vecteurs cmv comprenant des éléments de reconnaissance des microarn MA43285A (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201562258393P 2015-11-20 2015-11-20
US201662365259P 2016-07-21 2016-07-21

Publications (1)

Publication Number Publication Date
MA43285A true MA43285A (fr) 2018-09-26

Family

ID=58719315

Family Applications (1)

Application Number Title Priority Date Filing Date
MA043285A MA43285A (fr) 2015-11-20 2016-11-20 Vecteurs cmv comprenant des éléments de reconnaissance des microarn

Country Status (8)

Country Link
US (2) US10688164B2 (fr)
EP (1) EP3377636A4 (fr)
JP (2) JP7133468B2 (fr)
CN (2) CN108474003A (fr)
AU (1) AU2016355468B2 (fr)
CA (1) CA3005136A1 (fr)
MA (1) MA43285A (fr)
WO (1) WO2017087921A1 (fr)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2011143653A2 (fr) 2010-05-14 2011-11-17 Oregon Health & Science University Vecteurs recombinants du hcmv et du rhcmv, et leurs utilisations
WO2012170765A2 (fr) 2011-06-10 2012-12-13 Oregon Health & Science University Glycoprotéines de cmv et vecteurs recombinants cmv
PL2964769T3 (pl) 2013-03-05 2019-03-29 Oregon Health & Science University Wektory cytomegalowirusa umożliwiające kontrolę ukierunkowania limfocytów T
EA039174B1 (ru) 2014-07-16 2021-12-14 Орегон Хелс Энд Сайенс Юниверсити Цитомегаловирус человека, содержащий гетерологичный антиген, способ его получения, полинуклеотид, клетка, композиция и способ индуцирования иммунного ответа (варианты)
BR112017017092A2 (pt) 2015-02-10 2018-06-26 Univ Oregon Health & Science métodos e composições úteis na geração de respostas de células t cd8+ não canônicas
CN108474003A (zh) 2015-11-20 2018-08-31 俄勒冈健康与科学大学 包含微小rna识别元件的cmv载体
US11091775B2 (en) 2016-06-22 2021-08-17 Oregon Health And Science University Recombinant cytomegalovirus vectors as vaccines for tuberculosis
MA46588A (fr) 2016-10-18 2021-04-14 Univ Oregon Health & Science Vecteurs de cytomégalovirus déclenchant des lymphocytes t limités par des molécules e de complexe majeur d'histocompatibilité
GB201714430D0 (en) * 2017-09-07 2017-10-25 Micol Romain Compositions and processes for targeted delivery and expression and modulation of therapeutic components in tissue
EP3697806A4 (fr) 2017-10-17 2021-10-27 International AIDS Vaccine Initiative, Inc. Cassettes d'antigènes de la tuberculose
EP3980071A4 (fr) * 2019-06-07 2023-10-11 Oregon Health & Science University Réponses de lymphocytes t spécifiques d'un antigène associé à une tumeur
CR20220093A (es) 2019-08-20 2022-06-15 Univ Oregon Health & Science Modulación de las respuestas de células t por ul18 del citomegalovirus humano
WO2023034801A1 (fr) 2021-08-31 2023-03-09 Vir Biotechnology, Inc. Vecteurs de hcmv recombinants et leurs utilisations
IL310667A (en) 2021-08-31 2024-04-01 Vir Biotechnology Inc Tuberculosis vaccines

Family Cites Families (51)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5168062A (en) 1985-01-30 1992-12-01 University Of Iowa Research Foundation Transfer vectors and microorganisms containing human cytomegalovirus immediate-early promoter-regulatory DNA sequence
EP0319570B1 (fr) 1987-06-26 1995-02-22 Syntro Corporation Cytomegalovirus humain recombinant contenant des genes etrangers et son utilisation
US5273876A (en) 1987-06-26 1993-12-28 Syntro Corporation Recombinant human cytomegalovirus containing foreign gene
CA2089666C (fr) * 1990-08-16 2003-01-07 Kevin P. Anderson Oligonucleotides pour moduler les effets des infections a cytomegalovirus
EP0521427A1 (fr) 1991-07-05 1993-01-07 American Cyanamid Company Méthode d'identification de genes non-essentiels de cytomégalovirus humain, et de criblage d'inhibiteurs de cytomégalovirus humain
WO1995003399A2 (fr) 1993-07-19 1995-02-02 Cantab Pharmaceuticals Research Limited Procede de production destine a la preparation de virus neutralises
EP0758396B1 (fr) 1994-04-29 2006-07-26 Pharmacia & Upjohn Company LLC Vaccin contre le virus de l'immunodeficience feline
US5846806A (en) 1994-07-29 1998-12-08 American Cyanamid Company Identification of a human cytomegalovirus gene region involved in down-regulation of MHC class I heavy chain expression
ES2264136T3 (es) 1995-02-21 2006-12-16 Cantab Pharmaceuticals Research Limited Preparaciones virales, vectores, inmunogenos y sus vacunas.
KR19980703665A (ko) 1995-04-04 1998-12-05 카렌 크루벤 세포 표면상 제 1 류 ｍｈｃ 단백질의 수준이 낮은 유전적으로변형된 세포의 이식
DE69732498T2 (de) 1996-07-31 2006-04-27 Ortho-Mcneil Pharmaceutical, Inc. Erkennung von menschlichen cytomegalovirus genes, welche die expression von mhc klasse i schweren ketten erniedrigen
US20030138454A1 (en) 1997-06-09 2003-07-24 Oxxon Pharmaccines, Ltd. Vaccination method
DE19733364A1 (de) 1997-08-01 1999-02-04 Koszinowski Ulrich H Prof Verfahren zur Klonierung eines großen Virusgenoms
WO1999007869A1 (fr) 1997-08-05 1999-02-18 University Of Florida Vaccin vivant recombinant comprenant un virus ne se repliquant pas ou se repliquant sans efficacite
US6884785B2 (en) * 1999-06-17 2005-04-26 The Scripps Research Institute Compositions and methods for the treatment or prevention of autoimmune diabetes
US7204990B1 (en) 2000-11-28 2007-04-17 Medimmune Vaccines, Inc. Attenuation of cytomegalovirus virulence
US6740324B2 (en) 2001-02-02 2004-05-25 Chemocentryx, Inc. Methods and compositions useful for stimulating an immune response
WO2002066629A2 (fr) 2001-02-21 2002-08-29 Gabriele Hahn Vecteur de recombinaison contenant le genome infectieux du cytomegalovirus humain, conservant les caracteristiques de type sauvage d'isolats cliniques
GB0122232D0 (en) 2001-09-14 2001-11-07 Medical Res Council Gene expression
BR0212619A (pt) 2001-09-20 2004-08-17 Glaxo Group Ltd Sequência de nucleotìdeo, vetor, proteìna, composição farmacêutica, dispositivo de liberação intradérmica, método para tratar um paciente que sofre de uma doença ou é suscetìvel a ela, uso de uma sequência de nucleotìdeo, e, processo para a produção de um nucleotìdeo
US20030118568A1 (en) 2001-12-18 2003-06-26 Board Of Trustees Of The University Of Arkansas Viral stealth technology to prevent T cell-mediated rejection of xenografts
WO2003093455A2 (fr) 2002-04-30 2003-11-13 Avior Therapeutics, Inc. Vecteurs d'adenovirus utilises en immunotherapie
DE10232322A1 (de) 2002-07-16 2004-07-29 Hahn, Gabriele, Dr. Viral kodierte CxC determinieren den Gewebetropismus von HCMV
US7407744B2 (en) 2003-07-25 2008-08-05 The Regents Of The University Of California Cytomegalovirus gene function and methods for developing antivirals, anti-CMV vaccines, and CMV-based vectors
CA2567597C (fr) 2004-05-25 2014-03-18 Oregon Health And Science University Vaccination du virus de l'immunodeficience simienne (siv) et du virus de l'immunodeficience humaine (vih) utilisant des vecteurs de vaccin a base de rhcmv et hcmv
EP1602676A1 (fr) 2004-06-01 2005-12-07 SOLVAY (Société Anonyme) Compositions catalytiques
WO2006004661A1 (fr) 2004-06-25 2006-01-12 Medimmune Vaccines, Inc. Cytomegalovirus humain de recombinaison et vaccins contenant des antigenes heterologues
WO2006125983A1 (fr) 2005-05-23 2006-11-30 Oxxon Therapeutics Ltd Compositions permettant d'induire une reponse immunitaire contre l'hepatite b
WO2007027860A2 (fr) 2005-08-31 2007-03-08 Genvec, Inc. Vaccins contre la malaria a base de vecteurs adenoviraux
WO2008112146A2 (fr) 2007-03-07 2008-09-18 The Trustees Of The University Of Pennsylvania Imagerie partiellement parallèle en 2d avec reconstruction de données basée sur des voisins environnants d'espace k
BRPI0814060A2 (pt) 2007-07-06 2015-01-06 Trubion Pharmaceuticals Inc Peptídeos ligantes tendo um domínio de ligação específico disposto em c-terminal
PE20091434A1 (es) 2007-10-30 2009-10-17 Genentech Inc Purificacion de anticuerpos por cromatografia de intercambio cationico
US8074351B2 (en) * 2008-07-25 2011-12-13 Panasonic Corporation Part mounting device and part mounting method
US8883995B2 (en) 2009-03-06 2014-11-11 Icahn School Of Medicine At Mount Sinai Live attenuated influenza virus vaccines comprising microRNA response elements
AU2010334809C1 (en) 2009-12-23 2015-02-26 Agenus Inc. Binding members for human cytomegalovirus
EP2529227B1 (fr) 2010-01-27 2015-10-07 Oregon Health & Science University Préparations immunogènes à base de cytomégalovirus
EP2550362B1 (fr) 2010-03-25 2017-01-04 Oregon Health&Science University Glycoprotéines du cmv et vecteurs recombinés
US9078867B2 (en) 2010-05-05 2015-07-14 Christian Thirion Vaccine against beta-herpesvirus infection and use thereof
WO2011143653A2 (fr) 2010-05-14 2011-11-17 Oregon Health & Science University Vecteurs recombinants du hcmv et du rhcmv, et leurs utilisations
WO2012170765A2 (fr) 2011-06-10 2012-12-13 Oregon Health & Science University Glycoprotéines de cmv et vecteurs recombinants cmv
US20130156808A1 (en) 2011-11-22 2013-06-20 Stipan Jonjic Vaccine comprising beta-herpesvirus
JP6419706B2 (ja) * 2012-10-25 2018-11-07 トカジェン インコーポレーテッド ミニプロモーターカセットを含むレトロウイルスベクター
US8903341B2 (en) 2012-12-05 2014-12-02 Qualcomm Incorporated Successive interference cancellation (SIC) ordering algorithms for improved multiple-input multiple-output (MIMO) performance
PL2964769T3 (pl) 2013-03-05 2019-03-29 Oregon Health & Science University Wektory cytomegalowirusa umożliwiające kontrolę ukierunkowania limfocytów T
EA039174B1 (ru) 2014-07-16 2021-12-14 Орегон Хелс Энд Сайенс Юниверсити Цитомегаловирус человека, содержащий гетерологичный антиген, способ его получения, полинуклеотид, клетка, композиция и способ индуцирования иммунного ответа (варианты)
EP3048114A1 (fr) 2015-01-22 2016-07-27 Novartis AG Antigènes du cytomégalovirus et leurs utilisations
BR112017017092A2 (pt) 2015-02-10 2018-06-26 Univ Oregon Health & Science métodos e composições úteis na geração de respostas de células t cd8+ não canônicas
CN108474003A (zh) 2015-11-20 2018-08-31 俄勒冈健康与科学大学 包含微小rna识别元件的cmv载体
US11091775B2 (en) 2016-06-22 2021-08-17 Oregon Health And Science University Recombinant cytomegalovirus vectors as vaccines for tuberculosis
MA45455A (fr) 2016-06-27 2019-05-01 Juno Therapeutics Inc Procédé d'identification d'épitopes peptidiques, molécules qui se lient à de tels épitopes et utilisations associées
MA46588A (fr) 2016-10-18 2021-04-14 Univ Oregon Health & Science Vecteurs de cytomégalovirus déclenchant des lymphocytes t limités par des molécules e de complexe majeur d'histocompatibilité

Also Published As

Publication number Publication date
US20200368333A1 (en) 2020-11-26
JP7133468B2 (ja) 2022-09-08
EP3377636A4 (fr) 2019-11-06
US10688164B2 (en) 2020-06-23
AU2016355468B2 (en) 2022-12-15
CA3005136A1 (fr) 2017-05-26
WO2017087921A1 (fr) 2017-05-26
AU2016355468A1 (en) 2018-05-31
JP2022174123A (ja) 2022-11-22
CN108474003A (zh) 2018-08-31
EP3377636A1 (fr) 2018-09-26
JP2019502371A (ja) 2019-01-31
US20170143809A1 (en) 2017-05-25
CN116926128A (zh) 2023-10-24

Similar Documents

Publication Publication Date Title
MA43285A (fr) Vecteurs cmv comprenant des éléments de reconnaissance des microarn
IL279154B (en) Adenovirus-related vector
GB201401707D0 (en) Adeno-associated viral vectors
HUE041629T2 (hu) Festõegység
IL234766A (en) Fluorescent Imaging System
GB2539220B (en) Canvas system
HUE051749T2 (hu) Labirintusgomba mikroorganizmusokból származó szabályozó elemek
IL259964A (en) Adenovirus-associated vectors for the treatment of mucolipodosis type ii
PL3192358T3 (pl) System hodowli norek
GB2539061B (en) Comb
GB2543858B (en) Authentication system
GB2547622B (en) Excitation system
GB201505332D0 (en) Authentication system
GB2542888B (en) Fingerprint imaging
GB201610484D0 (en) Novel dyeing system
GB201610448D0 (en) Adeno-associated viral vector system
GB201603064D0 (en) Peg cover
HK1217864A2 (zh) 髮梳
GB201523164D0 (en) Drying system
GB201522855D0 (en) Recruitment consultancy & HR consultancy services
HU4596U (en) Axial fan cover increased construction
ES1149238Y (es) Estuche barajador de naipes.
GB201515999D0 (en) Authentication system
GB201506498D0 (en) Biometric system
ITUB20151906A1 (it) Fionda.