JP7126704B2 - 結腸直腸癌発症のリスクを評価するための方法 - Google Patents

結腸直腸癌発症のリスクを評価するための方法 Download PDF

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JP7126704B2
JP7126704B2 JP2018539370A JP2018539370A JP7126704B2 JP 7126704 B2 JP7126704 B2 JP 7126704B2 JP 2018539370 A JP2018539370 A JP 2018539370A JP 2018539370 A JP2018539370 A JP 2018539370A JP 7126704 B2 JP7126704 B2 JP 7126704B2
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colorectal cancer
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screening
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JP2019510473A5 (enExample
JP2019510473A (ja
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マーク・ジェンキンス
ダニエル・ブキャナン
ジョン・エル・ホッパー
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University of Melbourne
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    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B40/00—Libraries per se, e.g. arrays, mixtures
    • C40B40/04—Libraries containing only organic compounds
    • C40B40/06—Libraries containing nucleotides or polynucleotides, or derivatives thereof
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B20/00—ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
    • G16B20/20—Allele or variant detection, e.g. single nucleotide polymorphism [SNP] detection
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers

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  • Chemical & Material Sciences (AREA)
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  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
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  • Bioinformatics & Computational Biology (AREA)
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  • Evolutionary Biology (AREA)
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  • Spectroscopy & Molecular Physics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
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  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Medical Treatment And Welfare Office Work (AREA)
JP2018539370A 2016-01-28 2017-01-27 結腸直腸癌発症のリスクを評価するための方法 Active JP7126704B2 (ja)

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JP2022048257A JP2022104934A (ja) 2016-01-28 2022-03-24 結腸直腸癌発症のリスクを評価するための方法

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
AU2016900254A AU2016900254A0 (en) 2016-01-28 Methods for assessing risk of developing colorectal cancer
AU2016900254 2016-01-28
AU2016903246A AU2016903246A0 (en) 2016-08-16 Methods for assessing risk of developing colorectal cancer
AU2016903246 2016-08-16
PCT/AU2017/050066 WO2017127893A1 (en) 2016-01-28 2017-01-27 Methods for assessing risk of developing colorectal cancer

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US (1) US11773448B2 (enExample)
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KR (1) KR20180123480A (enExample)
CN (1) CN109072308A (enExample)
AU (1) AU2017212152B2 (enExample)
CA (1) CA3012783A1 (enExample)
ES (1) ES2976360T3 (enExample)
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Families Citing this family (10)

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JP7101143B2 (ja) * 2019-04-23 2022-07-14 ジェネシスヘルスケア株式会社 大腸がんのリスクを判定する方法
CN111057767A (zh) * 2020-01-19 2020-04-24 北京市第一中西医结合医院 一种中国人胃肠道肿瘤风险相关的位于mlh1基因的snp位点及其应用
CN111739642A (zh) * 2020-06-23 2020-10-02 杭州和壹医学检验所有限公司 一种结直肠癌风险预测方法、系统、计算机设备及可读存储介质
CN112029852B (zh) * 2020-09-24 2023-12-05 吉林大学 ONFH易感相关TNF-α、GREM1、TGF-β、CR2基因SNP检测物质
CN114672556A (zh) * 2020-12-25 2022-06-28 上海善准生物科技有限公司 结直肠癌分子分型及生存风险基因群及诊断产品和应用
CN114334142A (zh) * 2021-07-02 2022-04-12 中山大学肿瘤防治中心（中山大学附属肿瘤医院、中山大学肿瘤研究所） 一种用于结直肠癌发病风险预测的snp位点组合、发病风险预测模型及系统
CN115786501B (zh) * 2022-07-02 2023-06-16 武汉大学 一种与结直肠癌早期筛查和辅助诊断相关的增强子功能位点及其应用
WO2024138243A1 (en) * 2022-12-27 2024-07-04 Genetic Technologies Limited Colorectal cancer risk assessment
CN116949179A (zh) * 2023-07-04 2023-10-27 中国医学科学院北京协和医院 结直肠肿瘤多基因遗传风险评分系统、存储介质和电子设备
CN118658626A (zh) * 2024-08-19 2024-09-17 杭州和壹基因科技有限公司 一种基于机器学习的消化系统肿瘤的筛查方法及系统

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2008534009A (ja) 2005-04-01 2008-08-28 サムスン エレクトロニクス カンパニー リミテッド 大腸癌診断用の多重ｓｎｐ、それを含むマイクロアレイ及びキット、並びにそれを利用した大腸癌の診断方法

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS54147035A (en) 1978-05-10 1979-11-16 Minolta Camera Co Ltd Tessar type photographic lens placed behind aperture
US4240608A (en) 1979-11-02 1980-12-23 Acf Industries, Incorporated Controlled float seat arrangement for expanding gate valves
US5210015A (en) 1990-08-06 1993-05-11 Hoffman-La Roche Inc. Homogeneous assay system using the nuclease activity of a nucleic acid polymerase
AU726501B2 (en) 1996-06-04 2000-11-09 University Of Utah Research Foundation Monitoring hybridization during PCR
US6174170B1 (en) 1997-10-21 2001-01-16 Sony Corporation Display of text symbols associated with audio data reproducible from a recording disc
AU785425B2 (en) 2001-03-30 2007-05-17 Genetic Technologies Limited Methods of genomic analysis
WO2003021259A1 (en) 2001-09-05 2003-03-13 Perlegen Sciences, Inc. Selection of primer pairs
US6898531B2 (en) 2001-09-05 2005-05-24 Perlegen Sciences, Inc. Algorithms for selection of primer pairs
US20040023237A1 (en) 2001-11-26 2004-02-05 Perelegen Sciences Inc. Methods for genomic analysis
US6897025B2 (en) 2002-01-07 2005-05-24 Perlegen Sciences, Inc. Genetic analysis systems and methods
US20050019787A1 (en) 2003-04-03 2005-01-27 Perlegen Sciences, Inc., A Delaware Corporation Apparatus and methods for analyzing and characterizing nucleic acid sequences
US20040241657A1 (en) 2003-05-28 2004-12-02 Perlegen Sciences, Inc. Liver related disease compositions and methods
US7127355B2 (en) 2004-03-05 2006-10-24 Perlegen Sciences, Inc. Methods for genetic analysis
SG189774A1 (en) * 2008-04-10 2013-05-31 Genenews Corp Method and apparatus for determining a probability of colorectal cancer in a subject
CN102876791B (zh) * 2012-09-21 2015-09-02 湖北维达健基因技术有限公司 一种用于肛肠疾病患病风险评估基因芯片、制备方法及其试剂盒
EP3207161A4 (en) * 2014-10-14 2018-09-12 Wake Forest University Health Sciences Methods and compositions for correlating genetic markers with cancer risk
US10609708B1 (en) 2017-06-27 2020-03-31 Sprint Spectrum L.P. Use of TDD special subframe for transmission of small quantity of data

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2008534009A (ja) 2005-04-01 2008-08-28 サムスン エレクトロニクス カンパニー リミテッド 大腸癌診断用の多重ｓｎｐ、それを含むマイクロアレイ及びキット、並びにそれを利用した大腸癌の診断方法

Non-Patent Citations (10)

* Cited by examiner, † Cited by third party
Title
Cancer Epidemiology，2014年，Vol. 38, No. 5，pp. 583-590
Carcinogenesis，2014年，Vol. 35, No. 11，pp. 2512-2519
Gastroenterology，2015年，Vol. 148, No. 7，pp. 1330-1339
Nature Communications，2014年，5:4613，pp. 1-7
Nature Communications，2015年，6:7138，pp. 1-6
Nature Genetics，2012年，Vol. 44, No. 7，pp. 770-776
Nature Genetics，2014年，Vol. 46, No. 6，pp. 533-542
PLOS ONE，2014年，Vol. 9, Issue 6, e101178，pp. 1-11
Scientific Reports，2015年，5:10442，pp. 1-10
Scientific Reports，2015年，5:17369，pp. 1-12

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EP3408412A4 (en) 2020-01-15
AU2017212152B2 (en) 2019-07-11
WO2017127893A1 (en) 2017-08-03
IL260777A (enExample) 2018-09-20
EP3408412B1 (en) 2024-03-20
AU2017212152A1 (en) 2018-08-16
SG11201806432PA (en) 2018-08-30
IL260777B (en) 2022-09-01
US20190161802A1 (en) 2019-05-30
JP2019510473A (ja) 2019-04-18
EP3408412A1 (en) 2018-12-05
CA3012783A1 (en) 2017-08-03
MX2018009254A (es) 2019-05-06
JP2022104934A (ja) 2022-07-12
ES2976360T3 (es) 2024-07-30
CN109072308A (zh) 2018-12-21
US11773448B2 (en) 2023-10-03
KR20180123480A (ko) 2018-11-16

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