JP7118036B2 - 経皮的薬物送達装置および方法 - Google Patents
経皮的薬物送達装置および方法 Download PDFInfo
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
- A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
- A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
- A61M2037/0023—Drug applicators using microneedles
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- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Dermatology (AREA)
- Medical Informatics (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Media Introduction/Drainage Providing Device (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Description
本出願は、米国仮出願第61/996,149号(2014年4月30日出願)の利益を主張し、その内容全体を参照により本明細書に組み込む。
Claims (6)
- 経皮的薬物送達装置であって、
使用者の皮膚に固定されるように構成されたハウジングと、前記使用者の前記皮膚に挿入されたとき前記ハウジングとの間の相対的動きを許容するように、前記ハウジングに移動可能に取り付けられたマイクロニードル組立品とを備えるレセプタクルと、
前記レセプタクルに取り付けられるリザーバであって、前記リザーバが前記マイクロニードル組立品に供給される流体を包含する内部を持ち、
前記装置が組み立てられた時、経路に沿って外側位置から内側位置へ前記マイクロニードル組立品に対して前記リザーバが動かされるように前記装置が構成されており、
前記リザーバが、前記外側位置よりも前記内側位置で、前記マイクロニードル組立品に近く、
前記外側位置では、前記リザーバが前記マイクロニードル組立品と流体連通しておらず、
前記内側位置では、前記リザーバが前記マイクロニードル組立品と流体連通しているリザーバと、
前記経路にそってお互いに間隔を置いた複数のコネクタ部分であって、
前記リザーバを第一の位置に解除可能なように固定し、
前記リザーバを第二の位置に固定するように構成された複数のコネクタ部分とを備える装置。 - 前記複数のコネクタ部分がスナップフィットコネクタ部分を含む、請求項1に記載の装置。
- 前記リザーバを前記外側位置から前記内側位置へ動かすための押圧機構をさらに備える、請求項1に記載の装置。
- 前記押圧機構が押しボタンを備える、請求項3に記載の装置。
- 請求項3に記載の装置であって、前記押圧機構が外側押圧機構であり、前記装置が、
前記外側押圧機構に対して動かされるように、前記外側押圧機構に取り付けられた内側押圧機構と、
前記リザーバを少なくとも潰すために前記外側押圧機構および前記リザーバの両方に対して前記内側押圧機構を動かすように、前記内側押圧機構と動作可能なように関連している力供給体とを備える装置。 - 前記外側押圧機構と前記ハウジングとの間の所定の相対的動きに応答して前記内側押圧機構を解除するために、前記装置がラッチ機構をさらに備える、請求項5に記載の装置。
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JP2022082300A JP2022103381A (ja) | 2014-04-30 | 2022-05-19 | 経皮的薬物送達装置および方法 |
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US201461996149P | 2014-04-30 | 2014-04-30 | |
US61/996,149 | 2014-04-30 |
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JP2019139372A Active JP7118036B2 (ja) | 2014-04-30 | 2019-07-30 | 経皮的薬物送達装置および方法 |
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US (3) | US10232160B2 (ja) |
EP (4) | EP3137153A4 (ja) |
JP (3) | JP6566964B2 (ja) |
KR (1) | KR20160146842A (ja) |
CN (2) | CN111420266B (ja) |
AU (3) | AU2015253253B2 (ja) |
CA (2) | CA3189419A1 (ja) |
ES (1) | ES2943157T3 (ja) |
MX (2) | MX2016013610A (ja) |
RU (1) | RU2667621C2 (ja) |
WO (1) | WO2015168210A1 (ja) |
Families Citing this family (25)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN106232172B (zh) * | 2014-04-30 | 2020-05-22 | 索伦托治疗有限公司 | 透皮药物递送设备的插座部分和方法 |
CA3022463A1 (en) | 2016-04-29 | 2017-11-02 | Sorrento Therapeutics, Inc. | Microneedle array assembly, drug delivery device and method for administering liquid across a broad area at low pressure |
AU2017378040B2 (en) | 2016-12-16 | 2023-06-08 | Vivasor, Inc. | Application device for a fluid delivery apparatus and method of use |
WO2018111609A1 (en) | 2016-12-16 | 2018-06-21 | Kimberly-Clark Worldwide, Inc. | Attachment band for a fluid delivery apparatus and method of use |
KR20190088076A (ko) | 2016-12-16 | 2019-07-25 | 소렌토 쎄라퓨틱스, 인코포레이티드 | 유체 전달 장치 및 조립 방법 |
AU2017378018B2 (en) | 2016-12-16 | 2023-06-22 | Vivasor, Inc. | Fluid delivery apparatus having a gas extraction device and method of use |
CN116271481A (zh) * | 2016-12-16 | 2023-06-23 | 索伦托治疗有限公司 | 用于给予适合治疗偏头痛或丛集性头痛的药物的方法 |
WO2018111621A1 (en) | 2016-12-16 | 2018-06-21 | Kimberly-Clark Worldwide, Inc. | A fluid delivery apparatus having a controller assembly and method of use |
CN108211107B (zh) * | 2018-03-01 | 2023-08-15 | 中南民族大学 | 一种针对穴位持续给药的压力可控式微泡贴及制备方法 |
MX2022006702A (es) * | 2019-12-03 | 2022-07-19 | Sorrento Therapeutics Inc | Aparato de suministro de fluidos con microagujas. |
AU2020397052A1 (en) | 2019-12-05 | 2022-07-14 | Vivasor, Inc. | Method of treating cancer by administration of an anti-PD-1 or anti-PD-L1 therapeutic agent via a lymphatic delivery device |
EP4188204A4 (en) * | 2020-08-03 | 2024-07-10 | Qulab Medical Ltd | MINIMALLY INVASION SURVEILLANCE PATCH |
JP2024505198A (ja) | 2021-01-22 | 2024-02-05 | ソレント・セラピューティクス・インコーポレイテッド | コロナウイルスワクチンのマイクロリットルスケールのリンパ送達のためのデバイス |
US20220273923A1 (en) * | 2021-03-01 | 2022-09-01 | Deka Products Limited Partnership | Medical Agent Dispensing Systems, Methods, and Apparatuses |
WO2022192594A2 (en) | 2021-03-11 | 2022-09-15 | Sorrento Therapeutics, Inc. | Nucleic acid molecules and vaccines comprising same for the prevention and treatment of coronavirus infections and disease |
US11964121B2 (en) | 2021-10-13 | 2024-04-23 | Satio, Inc. | Mono dose dermal patch for pharmaceutical delivery |
US11877848B2 (en) | 2021-11-08 | 2024-01-23 | Satio, Inc. | Dermal patch for collecting a physiological sample |
US11452474B1 (en) | 2021-04-14 | 2022-09-27 | Satio, Inc. | Dual lever dermal patch system |
US12023156B2 (en) | 2021-10-13 | 2024-07-02 | Satio, Inc. | Dermal patch for collecting a physiological sample |
US12053284B2 (en) | 2021-11-08 | 2024-08-06 | Satio, Inc. | Dermal patch for collecting a physiological sample |
US12048543B2 (en) | 2021-11-08 | 2024-07-30 | Satio, Inc. | Dermal patch for collecting a physiological sample with removable vial |
CA3221925A1 (en) | 2021-06-09 | 2022-12-15 | Sorrento Therapeutics, Inc. | Method of treating cancer by administration of an anti-pd-1 or anti-pd-l1 therapeutic agent via a lymphatic microneedle delivery device |
KR20240056524A (ko) | 2021-08-18 | 2024-04-30 | 소렌토 쎄라퓨틱스, 인코포레이티드 | 림프계를 표적화하는 치료학적 제제 |
CN114010931B (zh) * | 2021-12-01 | 2022-10-28 | 深圳市深鸿涛贸易有限公司 | 一种医疗用皮肤科烫伤皮肤敷药设备 |
DE102023101977A1 (de) * | 2023-01-27 | 2024-08-01 | Lts Lohmann Therapie-Systeme Ag. | Applikationsvorrichtung für Mikronadeln, System zur Mikronadelapplikation und Verfahren zur Bereitstellung eines Systems zur Mikronadelapplikation |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2006515207A (ja) | 2003-01-07 | 2006-05-25 | ベクトン・ディキンソン・アンド・カンパニー | 使い捨て可能な注入装置 |
JP2013516274A (ja) | 2010-01-08 | 2013-05-13 | ウィスコンシン・アラムナイ・リサーチ・ファウンデーション | 微小針を用いた薬物送達装置のための袋構成体 |
US20130345638A1 (en) | 2012-06-25 | 2013-12-26 | Flugen, Inc. | Multiple drug delivery device |
Family Cites Families (41)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5279544A (en) | 1990-12-13 | 1994-01-18 | Sil Medics Ltd. | Transdermal or interdermal drug delivery devices |
US6623457B1 (en) | 1999-09-22 | 2003-09-23 | Becton, Dickinson And Company | Method and apparatus for the transdermal administration of a substance |
US6656147B1 (en) | 2000-07-17 | 2003-12-02 | Becton, Dickinson And Company | Method and delivery device for the transdermal administration of a substance |
IL155375A0 (en) * | 2000-10-13 | 2003-11-23 | Alza Corp | Microblade array impact applicator |
HUP0302924A2 (en) | 2000-10-26 | 2003-12-29 | Alza Corp | Transdermal drug delivery devices having coated microprotrusions |
US7850663B2 (en) * | 2001-01-12 | 2010-12-14 | Becton, Dickinson And Company | Medicament microdevice delivery system, cartridge and method of use |
AU2002333554C1 (en) * | 2001-09-12 | 2008-12-11 | Becton, Dickinson And Company | Microneedle-based pen device for drug delivery and method for using same |
US6830562B2 (en) | 2001-09-27 | 2004-12-14 | Unomedical A/S | Injector device for placing a subcutaneous infusion set |
US6780171B2 (en) | 2002-04-02 | 2004-08-24 | Becton, Dickinson And Company | Intradermal delivery device |
GB0302662D0 (en) | 2003-02-05 | 2003-03-12 | Strakan Ltd | Transdermal granisetron |
US7670314B2 (en) | 2004-02-17 | 2010-03-02 | Children's Hospital Medical Center | Injection device for administering a vaccine |
WO2006015299A2 (en) | 2004-07-30 | 2006-02-09 | Microchips, Inc. | Multi-reservoir device for transdermal drug delivery and sensing |
JPWO2006016647A1 (ja) | 2004-08-12 | 2008-05-01 | 久光製薬株式会社 | マイクロニードル付き経皮薬物投与装置 |
US20080009801A1 (en) | 2004-12-02 | 2008-01-10 | Nickel Janice H | Method for dispensing material into a drug delivery device |
JPWO2007091608A1 (ja) | 2006-02-10 | 2009-07-02 | 久光製薬株式会社 | マイクロニードル付き経皮薬物投与装置 |
CA2536845C (en) * | 2006-02-16 | 2009-10-27 | Pka Softtouch Corp. | Drug delivery device |
FR2912919B1 (fr) * | 2007-02-22 | 2009-05-01 | Bernard Perriere | Dispositif d'injection miniaturise a usage medical |
CN101977643A (zh) * | 2008-03-24 | 2011-02-16 | 奥林巴斯株式会社 | 药剂投放装置 |
US9370621B2 (en) * | 2008-12-16 | 2016-06-21 | Medtronic Minimed, Inc. | Needle insertion systems and methods |
US8337466B2 (en) * | 2009-03-30 | 2012-12-25 | Lifemedix, Llc | Manual pump for intravenous fluids |
EP2424611A4 (en) * | 2009-05-01 | 2012-10-24 | Nanbu Plastics Co Ltd | DEVICE FOR TRANSDERMAL ADMINISTRATIONS |
ES2661063T3 (es) * | 2009-07-31 | 2018-03-27 | 3M Innovative Properties Company | Matrices de micro agujas huecas |
JP5558047B2 (ja) * | 2009-08-13 | 2014-07-23 | 深江化成株式会社 | 物質供給装置 |
IN2012DN02600A (ja) * | 2009-10-13 | 2015-09-04 | Valeritas Inc | |
US20110144591A1 (en) | 2009-12-11 | 2011-06-16 | Ross Russell F | Transdermal Delivery Device |
DK2512560T3 (en) * | 2009-12-16 | 2018-07-16 | Becton Dickinson Co | Even injector device |
ES2714698T3 (es) * | 2009-12-16 | 2019-05-29 | Becton Dickinson Co | Dispositivo de autoinyección |
US20110172609A1 (en) | 2010-01-08 | 2011-07-14 | Ratio, Inc. | Microneedle component assembly for drug delivery device |
US20110172639A1 (en) * | 2010-01-08 | 2011-07-14 | Ratio, Inc. | Device and method for delivery of microneedle to desired depth within the skin |
US20110172637A1 (en) * | 2010-01-08 | 2011-07-14 | Ratio, Inc. | Drug delivery device including tissue support structure |
DK2563453T3 (en) | 2010-04-28 | 2017-05-22 | Kimberly Clark Co | Nano-patterned medical device with improved cellular interaction and process for its preparation |
EP2595602B1 (en) * | 2010-07-21 | 2018-05-23 | Allergan, Inc. | SUSTAINED RELEASE siRNA FOR OCULAR DRUG DELIVERY |
US9173994B2 (en) | 2010-08-20 | 2015-11-03 | Purdue Research Foundation | Touch-actuated micropump for transdermal drug delivery and method of use |
US9017289B2 (en) * | 2010-11-03 | 2015-04-28 | Covidien Lp | Transdermal fluid delivery device |
US8814831B2 (en) | 2010-11-30 | 2014-08-26 | Becton, Dickinson And Company | Ballistic microneedle infusion device |
EP2460553A1 (fr) * | 2010-12-02 | 2012-06-06 | Debiotech S.A. | Dispositif pour l'insertion d'aiguilles |
WO2012088154A1 (en) * | 2010-12-22 | 2012-06-28 | Valeritas, Inc. | Microneedle patch applicator |
WO2013112877A1 (en) | 2012-01-25 | 2013-08-01 | Tasso, Inc. | Handheld device for drawing, collecting, and analyzing bodily fluid |
WO2014059104A1 (en) * | 2012-10-10 | 2014-04-17 | 3M Innovative Properties Company | Applicator and method for applying a microneedle device to skin |
PL3003459T3 (pl) * | 2013-05-31 | 2018-11-30 | 3M Innovative Properties Company | Mikroigłowy aparat iniekcyjny zawierający odwrócony element wykonawczy |
CN203355122U (zh) * | 2013-06-13 | 2013-12-25 | 陈彦彪 | 一种电动微针组件 |
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Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2006515207A (ja) | 2003-01-07 | 2006-05-25 | ベクトン・ディキンソン・アンド・カンパニー | 使い捨て可能な注入装置 |
JP2013516274A (ja) | 2010-01-08 | 2013-05-13 | ウィスコンシン・アラムナイ・リサーチ・ファウンデーション | 微小針を用いた薬物送達装置のための袋構成体 |
US20130345638A1 (en) | 2012-06-25 | 2013-12-26 | Flugen, Inc. | Multiple drug delivery device |
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