JP7115755B2 - 肝損傷の処置における使用のためのマクロファージに基づく治療法 - Google Patents
肝損傷の処置における使用のためのマクロファージに基づく治療法 Download PDFInfo
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- JP7115755B2 JP7115755B2 JP2019515418A JP2019515418A JP7115755B2 JP 7115755 B2 JP7115755 B2 JP 7115755B2 JP 2019515418 A JP2019515418 A JP 2019515418A JP 2019515418 A JP2019515418 A JP 2019515418A JP 7115755 B2 JP7115755 B2 JP 7115755B2
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- A61K2239/31—Indexing codes associated with cellular immunotherapy of group A61K40/00 characterized by the route of administration
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2239/00—Indexing codes associated with cellular immunotherapy of group A61K40/00
- A61K2239/38—Indexing codes associated with cellular immunotherapy of group A61K40/00 characterised by the dose, timing or administration schedule
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- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
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- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/20—Cytokines; Chemokines
- C12N2501/23—Interleukins [IL]
- C12N2501/2304—Interleukin-4 (IL-4)
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- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/20—Cytokines; Chemokines
- C12N2501/23—Interleukins [IL]
- C12N2501/2313—Interleukin-13 (IL-13)
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Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB1615923.8A GB201615923D0 (en) | 2016-09-19 | 2016-09-19 | Macrophage-based therapy |
| GB1615923.8 | 2016-09-19 | ||
| GB1707183.8 | 2017-05-05 | ||
| GBGB1707183.8A GB201707183D0 (en) | 2017-05-05 | 2017-05-05 | Macrophage-based therapy |
| PCT/GB2017/052769 WO2018051136A1 (en) | 2016-09-19 | 2017-09-18 | Macrophage-based therapy for use in the treatment of liver injury |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2019532634A JP2019532634A (ja) | 2019-11-14 |
| JP2019532634A5 JP2019532634A5 (enExample) | 2020-11-12 |
| JP7115755B2 true JP7115755B2 (ja) | 2022-08-09 |
Family
ID=60083347
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019515418A Active JP7115755B2 (ja) | 2016-09-19 | 2017-09-18 | 肝損傷の処置における使用のためのマクロファージに基づく治療法 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US11285174B2 (enExample) |
| EP (2) | EP3515460B1 (enExample) |
| JP (1) | JP7115755B2 (enExample) |
| CN (1) | CN109789163A (enExample) |
| AU (1) | AU2017328913B2 (enExample) |
| WO (1) | WO2018051136A1 (enExample) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2896548T3 (es) | 2015-10-30 | 2022-02-24 | Biolamina Ab | Métodos de producción de hepatocitos |
| GB2572005A (en) | 2018-03-16 | 2019-09-18 | Univ Court Univ Of Edinburgh | Macrophage-based therapy |
| CN112955161B (zh) * | 2018-09-06 | 2024-12-17 | 泰克年研究发展基金会公司 | 通过活化细胞修复组织 |
| GB202007905D0 (en) * | 2020-05-27 | 2020-07-08 | Univ Edinburgh | Cryopressing macrophages |
| CN111933006B (zh) * | 2020-07-30 | 2022-06-03 | 四川大学华西医院 | 一种模拟巨噬细胞改善小鼠急性肾损伤实验的方法及系统 |
| CN114622017A (zh) * | 2020-12-14 | 2022-06-14 | 中山大学孙逸仙纪念医院 | Isg15、isg15诱导的巨噬细胞及其分泌物在肿瘤治疗中的应用 |
| WO2023075623A1 (en) * | 2021-10-26 | 2023-05-04 | Ineb (Instituto Nacional De Engenharia Biomédica) | Macrophage phenoypes for use in the treatment of intravertebral discs |
| CN115212320B (zh) * | 2022-08-04 | 2025-07-15 | 温州医科大学慈溪生物医药研究院 | 一种双靶向脂质体及其应用 |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103977029A (zh) | 2014-04-11 | 2014-08-13 | 中国人民解放军第四军医大学 | 经典激活的巨噬细胞在治疗肝纤维化的应用 |
| WO2016114723A1 (en) | 2015-01-16 | 2016-07-21 | Agency For Science, Technology And Research | Differentiation of macrophages from pluripotent stem cells |
-
2017
- 2017-09-18 EP EP17783964.4A patent/EP3515460B1/en active Active
- 2017-09-18 CN CN201780056623.2A patent/CN109789163A/zh active Pending
- 2017-09-18 AU AU2017328913A patent/AU2017328913B2/en active Active
- 2017-09-18 WO PCT/GB2017/052769 patent/WO2018051136A1/en not_active Ceased
- 2017-09-18 JP JP2019515418A patent/JP7115755B2/ja active Active
- 2017-09-18 EP EP25198861.4A patent/EP4640237A2/en active Pending
- 2017-09-18 US US16/331,787 patent/US11285174B2/en active Active
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103977029A (zh) | 2014-04-11 | 2014-08-13 | 中国人民解放军第四军医大学 | 经典激活的巨噬细胞在治疗肝纤维化的应用 |
| WO2016114723A1 (en) | 2015-01-16 | 2016-07-21 | Agency For Science, Technology And Research | Differentiation of macrophages from pluripotent stem cells |
Non-Patent Citations (4)
| Title |
|---|
| Immunity,2010,Vol.32,p.593-604 |
| J.Immunol.Methods,2012,Vol.385,p.1-14 |
| J.Leukoc.Biol.,2008,Vol.84,p.1410-1421 |
| Nat. Rev. Immunol., 2003, Vol. 3, p. 23-35 |
Also Published As
| Publication number | Publication date |
|---|---|
| EP3515460B1 (en) | 2025-09-17 |
| JP2019532634A (ja) | 2019-11-14 |
| US11285174B2 (en) | 2022-03-29 |
| CN109789163A (zh) | 2019-05-21 |
| WO2018051136A9 (en) | 2019-02-07 |
| AU2017328913A1 (en) | 2019-02-28 |
| AU2017328913B2 (en) | 2023-08-17 |
| EP4640237A2 (en) | 2025-10-29 |
| EP3515460A1 (en) | 2019-07-31 |
| US20190240256A1 (en) | 2019-08-08 |
| WO2018051136A1 (en) | 2018-03-22 |
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