JP7093955B2 - 治療剤の送達のためのケイ酸金属塩を含むポーラスシリコン物質 - Google Patents

治療剤の送達のためのケイ酸金属塩を含むポーラスシリコン物質 Download PDF

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JP7093955B2
JP7093955B2 JP2019505332A JP2019505332A JP7093955B2 JP 7093955 B2 JP7093955 B2 JP 7093955B2 JP 2019505332 A JP2019505332 A JP 2019505332A JP 2019505332 A JP2019505332 A JP 2019505332A JP 7093955 B2 JP7093955 B2 JP 7093955B2
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porous silicon
composition according
particles
agent
composition
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JP2019511582A (ja
JP2019511582A5 (enExample
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マイケル ジェイ． セーラー，
ジニョン カン，
ジンミョン ジュ，
エミリー アングリン，
エスター クォン，
マシュー スカラーク，
サンギータ バティア，
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University of California San Diego UCSD
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University of California San Diego UCSD
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
    • A61K47/6921—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a particulate, a powder, an adsorbate, a bead or a sphere
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    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
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    • A61K49/0091—Microparticle, microcapsule, microbubble, microsphere, microbead, i.e. having a size or diameter higher or equal to 1 micrometer
    • A61K49/0093—Nanoparticle, nanocapsule, nanobubble, nanosphere, nanobead, i.e. having a size or diameter smaller than 1 micrometer, e.g. polymeric nanoparticle
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    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A61K9/5192—Processes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
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    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/10—Type of nucleic acid
    • C12N2310/14—Type of nucleic acid interfering nucleic acids [NA]

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JP2019505332A 2016-04-14 2017-04-14 治療剤の送達のためのケイ酸金属塩を含むポーラスシリコン物質 Active JP7093955B2 (ja)

Priority Applications (2)

Application Number Priority Date Filing Date Title
JP2022094681A JP2022121463A (ja) 2016-04-14 2022-06-10 治療剤の送達のためのケイ酸金属塩を含むポーラスシリコン物質
JP2024064709A JP2024094359A (ja) 2016-04-14 2024-04-12 治療剤の送達のためのケイ酸金属塩を含むポーラスシリコン物質

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US201662322782P 2016-04-14 2016-04-14
US62/322,782 2016-04-14
PCT/US2017/027772 WO2017181115A1 (en) 2016-04-14 2017-04-14 Porous silicon materials comprising a metal silicate for delivery of therapeutic agents

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JP2022094681A Division JP2022121463A (ja) 2016-04-14 2022-06-10 治療剤の送達のためのケイ酸金属塩を含むポーラスシリコン物質

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JP2019511582A JP2019511582A (ja) 2019-04-25
JP2019511582A5 JP2019511582A5 (enExample) 2020-05-28
JP7093955B2 true JP7093955B2 (ja) 2022-07-01

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JP2019505332A Active JP7093955B2 (ja) 2016-04-14 2017-04-14 治療剤の送達のためのケイ酸金属塩を含むポーラスシリコン物質
JP2022094681A Withdrawn JP2022121463A (ja) 2016-04-14 2022-06-10 治療剤の送達のためのケイ酸金属塩を含むポーラスシリコン物質
JP2024064709A Pending JP2024094359A (ja) 2016-04-14 2024-04-12 治療剤の送達のためのケイ酸金属塩を含むポーラスシリコン物質

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JP2022094681A Withdrawn JP2022121463A (ja) 2016-04-14 2022-06-10 治療剤の送達のためのケイ酸金属塩を含むポーラスシリコン物質
JP2024064709A Pending JP2024094359A (ja) 2016-04-14 2024-04-12 治療剤の送達のためのケイ酸金属塩を含むポーラスシリコン物質

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US (1) US20210177770A1 (enExample)
EP (1) EP3442540A4 (enExample)
JP (3) JP7093955B2 (enExample)
CN (2) CN114949250A (enExample)
AU (2) AU2017250300B2 (enExample)
CA (1) CA3021001A1 (enExample)
WO (1) WO2017181115A1 (enExample)

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EP3773730A4 (en) 2018-03-27 2021-12-29 The Regents of The University of California Drug delivery formulations
IL280880B2 (en) 2018-08-27 2025-04-01 Regeneron Pharma Using Raman Spectroscopy in Downstream Purification
JP7335078B2 (ja) * 2019-02-21 2023-08-29 アサヒグループ食品株式会社 ペプチド含有物を含む組成物の変色抑制方法、並びに粉末組成物、顆粒、及び錠剤
JP7320303B2 (ja) * 2019-02-22 2023-08-03 レモネックス インコーポレイテッド 免疫活性もしくは癌の予防または治療用の医薬組成物
EP3714879A1 (en) 2019-03-28 2020-09-30 Sisaf Ltd Structured encapsulated silicon-containing particles
GB201904336D0 (en) * 2019-03-28 2019-05-15 Sisaf Ltd A delivery system
GB201904334D0 (en) 2019-03-28 2019-05-15 Sisaf Ltd Carrier system for preparing herbaceous extracts
GB201904337D0 (en) * 2019-03-28 2019-05-15 Sisaf Ltd A delivery system
GB202110644D0 (en) * 2021-07-23 2021-09-08 Sisaf Ltd Improved nucleic acid vector particles
CN114983977B (zh) * 2022-06-30 2023-03-10 浙江大学 铜-聚多巴胺共修饰的多孔硅颗粒及其制备方法和应用
CN116570721A (zh) * 2023-02-06 2023-08-11 四川农业大学 一种t-705@msn-rvg脑内药物递送载体及其制备方法
CN116510003B (zh) * 2023-06-20 2023-10-20 中国人民解放军军事科学院军事医学研究院 一种负载鼠疫菌rF1-V10蛋白的锰基纳米颗粒疫苗及其在抗鼠疫菌中的应用
WO2025098983A1 (en) * 2023-11-07 2025-05-15 Evonik Operations Gmbh Rna storage and delivery

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JP2014527980A (ja) 2011-09-21 2014-10-23 イッサム リサーチ ディべロップメント カンパニー オブ ザ ヘブライ ユニバーシティー オブ エルサレム，リミテッドＹｉｓｓｕｍ Ｒｅｓｅａｒｃｈ Ｄｅｖｅｌｏｐｍｅｎｔ Ｃｏｍｐａｎｙ Ｏｆ Ｔｈｅ Ｈｅｂｒｅｗ Ｕｎｉｖｅｒｓｉｔｙ Ｏｆ Ｊｅｒｕｓａｌｅｍ，Ｌｔｄ． ナノ送達システム
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