JP7051687B2 - P65の転写調節ドメインと蛋白質運搬ドメインとを含む新規融合蛋白質およびその用途 - Google Patents

P65の転写調節ドメインと蛋白質運搬ドメインとを含む新規融合蛋白質およびその用途 Download PDF

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JP7051687B2
JP7051687B2 JP2018536197A JP2018536197A JP7051687B2 JP 7051687 B2 JP7051687 B2 JP 7051687B2 JP 2018536197 A JP2018536197 A JP 2018536197A JP 2018536197 A JP2018536197 A JP 2018536197A JP 7051687 B2 JP7051687 B2 JP 7051687B2
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fusion protein
disease
sequence
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protein
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JP2019507117A (ja
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キョウ イ、サン
トン パク、ソン
ヤン、チョン-チン
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グッド ティー セルズ、 インコーポレイテッド
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K19/00Hybrid peptides, i.e. peptides covalently bound to nucleic acids, or non-covalently bound protein-protein complexes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/62DNA sequences coding for fusion proteins

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  • Health & Medical Sciences (AREA)
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  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
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  • Wood Science & Technology (AREA)
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  • Pharmacology & Pharmacy (AREA)
  • Immunology (AREA)
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  • Microbiology (AREA)
  • Toxicology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
JP2018536197A 2016-01-06 2016-01-06 P65の転写調節ドメインと蛋白質運搬ドメインとを含む新規融合蛋白質およびその用途 Active JP7051687B2 (ja)

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PCT/KR2016/000104 WO2017119521A1 (fr) 2016-01-06 2016-01-06 Nouvelle protéine de fusion comprenant le domaine de modulation de transcription de p65 et domaine de transport de protéine et son utilisation

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JP2019507117A JP2019507117A (ja) 2019-03-14
JP7051687B2 true JP7051687B2 (ja) 2022-04-11

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JP (1) JP7051687B2 (fr)
AU (1) AU2016385177B2 (fr)
CA (1) CA3010811A1 (fr)
WO (1) WO2017119521A1 (fr)

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2010509181A (ja) * 2005-11-04 2010-03-25 フォーヒューマンテック・カンパニー・リミテッド 融合ポリペプチドを細胞へ輸送する方法
EP2607380B1 (fr) * 2010-08-20 2018-10-10 Lee, Sang-Kyou Protéine de fusion comportant un domaine régulant la transactivation d'un facteur de transcription et un domaine de transduction de protéine, et inhibiteur de fonction de facteur de transcription comprenant cette protéine
KR101525856B1 (ko) * 2010-08-20 2015-06-04 연세대학교 산학협력단 전사인자의 dna 결합 도메인 및 단백질 운반 도메인을 포함하는 융합단백질을 가지는 전사인자 억제제 및 이의 제조방법

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
Database GenPept[online],Accession No.NP_033071
Scientific Reports,2015年,5:8133,pp.1-13

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AU2016385177B2 (en) 2023-10-19
WO2017119521A1 (fr) 2017-07-13
CA3010811A1 (fr) 2017-07-13
JP2019507117A (ja) 2019-03-14
AU2016385177A1 (en) 2018-08-09

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