JP7046603B2 - 微生物を検出し同定するための方法およびデバイス - Google Patents

微生物を検出し同定するための方法およびデバイス Download PDF

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JP7046603B2
JP7046603B2 JP2017515830A JP2017515830A JP7046603B2 JP 7046603 B2 JP7046603 B2 JP 7046603B2 JP 2017515830 A JP2017515830 A JP 2017515830A JP 2017515830 A JP2017515830 A JP 2017515830A JP 7046603 B2 JP7046603 B2 JP 7046603B2
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microbial
sample
dna
genetic material
nucleic acid
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アロン シンガー
ランジット プラカシュ
シュリーニヴァス ラピレディー
ヨーク ノーリング
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ヒーリクスバインド インコーポレイテッド
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    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6888—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
    • C12Q1/689—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for bacteria
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    • B01L3/502715—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by interfacing components, e.g. fluidic, electrical, optical or mechanical interfaces
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    • B01L3/502753—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by bulk separation arrangements on lab-on-a-chip devices, e.g. for filtration or centrifugation
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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1003—Extracting or separating nucleic acids from biological samples, e.g. pure separation or isolation methods; Conditions, buffers or apparatuses therefor
    • C12N15/1006—Extracting or separating nucleic acids from biological samples, e.g. pure separation or isolation methods; Conditions, buffers or apparatuses therefor by means of a solid support carrier, e.g. particles, polymers
    • C12N15/101—Extracting or separating nucleic acids from biological samples, e.g. pure separation or isolation methods; Conditions, buffers or apparatuses therefor by means of a solid support carrier, e.g. particles, polymers by chromatography, e.g. electrophoresis, ion-exchange, reverse phase
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    • C12Q1/6806—Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
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  • Proteomics, Peptides & Aminoacids (AREA)
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  • Biochemistry (AREA)
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  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Clinical Laboratory Science (AREA)
  • Hematology (AREA)
  • Dispersion Chemistry (AREA)
  • Plant Pathology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
JP2017515830A 2014-09-17 2015-09-17 微生物を検出し同定するための方法およびデバイス Active JP7046603B2 (ja)

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JP2021203271A JP7594523B2 (ja) 2014-09-17 2021-12-15 微生物を検出し同定するための方法およびデバイス
JP2024107218A JP2024156666A (ja) 2014-09-17 2024-07-03 微生物を検出し同定するための方法およびデバイス

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US201462051447P 2014-09-17 2014-09-17
US62/051,447 2014-09-17
PCT/US2015/050741 WO2016044621A1 (en) 2014-09-17 2015-09-17 Methods and devices for detecting and identifying microorganisms

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CA2961510A1 (en) * 2014-09-17 2016-03-24 Helixbind, Inc. Methods and devices for detecting and identifying microorganisms
WO2017160820A1 (en) 2016-03-14 2017-09-21 Helixbind, Inc. Integrated fluidic devices and related methods
CN110832085A (zh) * 2017-04-03 2020-02-21 海利克斯拜恩德股份有限公司 用于鉴定微生物感染的方法和装置
WO2019116034A1 (en) * 2017-12-12 2019-06-20 Cell Therapy Catapult Limited Microbial enrichment method
EP3803326A4 (en) * 2018-05-25 2022-02-23 Qvella Corporation METHODS AND COMPOSITIONS FOR SELECTIVE LYSIS OF BLOOD CELLS AND SEPARATION OF MICROBIAL CELLS
CA3137012A1 (en) 2019-04-16 2020-10-22 Helixbind, Inc. Methods and devices for ultrasensitive direct detection of microorganisms
WO2021055495A1 (en) * 2019-09-17 2021-03-25 Juno Bio Limited Methods and systems for selective nucleic acid depletion
CN115175765B (zh) 2020-02-25 2024-05-07 海利克斯拜恩德股份有限公司 用于流体系统的试剂载体
CN115703993B (zh) * 2021-08-17 2025-08-01 北京京东方技术开发有限公司 微流控芯片、其核酸提取方法及核酸提取装置
WO2023141916A1 (zh) 2022-01-28 2023-08-03 京东方科技集团股份有限公司 芯片散热装置和核酸提取设备

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WO2011028494A2 (en) 2009-08-24 2011-03-10 Trustees Of Boston University Label-free sensing of pna-dna complexes using nanopores
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JP2013512685A (ja) 2009-12-08 2013-04-18 バイオカルティス、ソシエテ、アノニム 細胞の選択的溶解
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WO2016044621A1 (en) 2016-03-24
JP2017527301A (ja) 2017-09-21
CA2961510A1 (en) 2016-03-24
EP3194626B1 (en) 2020-02-12
US11414712B2 (en) 2022-08-16
US20230183820A1 (en) 2023-06-15
JP7594523B2 (ja) 2024-12-04
EP3194626A1 (en) 2017-07-26
JP2024156666A (ja) 2024-11-06
JP2022050415A (ja) 2022-03-30
US20170292146A1 (en) 2017-10-12
EP3696267A1 (en) 2020-08-19
EP3194626A4 (en) 2018-06-20

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