JP7041120B2 - 飲み込み易い被膜及びそれにより被覆された基材 - Google Patents
飲み込み易い被膜及びそれにより被覆された基材 Download PDFInfo
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- JP7041120B2 JP7041120B2 JP2019505520A JP2019505520A JP7041120B2 JP 7041120 B2 JP7041120 B2 JP 7041120B2 JP 2019505520 A JP2019505520 A JP 2019505520A JP 2019505520 A JP2019505520 A JP 2019505520A JP 7041120 B2 JP7041120 B2 JP 7041120B2
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- JP
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- Prior art keywords
- weight
- water
- guar gum
- composition
- coated
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 239000000758 substrate Substances 0.000 title claims description 74
- 238000000576 coating method Methods 0.000 title claims description 40
- 239000011248 coating agent Substances 0.000 title claims description 31
- 239000000203 mixture Substances 0.000 claims description 127
- 238000009501 film coating Methods 0.000 claims description 78
- 239000007888 film coating Substances 0.000 claims description 78
- 239000006185 dispersion Substances 0.000 claims description 69
- 229920002907 Guar gum Polymers 0.000 claims description 67
- 239000000665 guar gum Substances 0.000 claims description 67
- 235000010417 guar gum Nutrition 0.000 claims description 67
- 229960002154 guar gum Drugs 0.000 claims description 67
- 230000003068 static effect Effects 0.000 claims description 38
- 238000000034 method Methods 0.000 claims description 34
- 229920003169 water-soluble polymer Polymers 0.000 claims description 34
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 32
- 229920000642 polymer Polymers 0.000 claims description 29
- 229920002774 Maltodextrin Polymers 0.000 claims description 24
- 229920002554 vinyl polymer Polymers 0.000 claims description 22
- 239000005913 Maltodextrin Substances 0.000 claims description 21
- 229940035034 maltodextrin Drugs 0.000 claims description 21
- 239000004014 plasticizer Substances 0.000 claims description 16
- 239000000049 pigment Substances 0.000 claims description 15
- 239000000314 lubricant Substances 0.000 claims description 14
- 229920003088 hydroxypropyl methyl cellulose Polymers 0.000 claims description 13
- 125000000391 vinyl group Chemical group [H]C([*])=C([H])[H] 0.000 claims description 12
- 239000001866 hydroxypropyl methyl cellulose Substances 0.000 claims description 10
- 235000010979 hydroxypropyl methyl cellulose Nutrition 0.000 claims description 10
- 229960003943 hypromellose Drugs 0.000 claims description 10
- 239000004372 Polyvinyl alcohol Substances 0.000 claims description 8
- 229920002451 polyvinyl alcohol Polymers 0.000 claims description 8
- 239000002202 Polyethylene glycol Substances 0.000 claims description 6
- 150000004667 medium chain fatty acids Chemical class 0.000 claims description 6
- 229920001223 polyethylene glycol Polymers 0.000 claims description 6
- 229920001577 copolymer Polymers 0.000 claims description 5
- 239000000454 talc Substances 0.000 claims description 5
- 229910052623 talc Inorganic materials 0.000 claims description 5
- 239000004354 Hydroxyethyl cellulose Substances 0.000 claims description 4
- 229920000663 Hydroxyethyl cellulose Polymers 0.000 claims description 4
- 229920002153 Hydroxypropyl cellulose Polymers 0.000 claims description 4
- 235000019447 hydroxyethyl cellulose Nutrition 0.000 claims description 4
- 239000001863 hydroxypropyl cellulose Substances 0.000 claims description 4
- 235000010977 hydroxypropyl cellulose Nutrition 0.000 claims description 4
- UFTFJSFQGQCHQW-UHFFFAOYSA-N triformin Chemical compound O=COCC(OC=O)COC=O UFTFJSFQGQCHQW-UHFFFAOYSA-N 0.000 claims description 4
- 229920003083 Kollidon® VA64 Polymers 0.000 claims description 3
- DPXJVFZANSGRMM-UHFFFAOYSA-N acetic acid;2,3,4,5,6-pentahydroxyhexanal;sodium Chemical compound [Na].CC(O)=O.OCC(O)C(O)C(O)C(O)C=O DPXJVFZANSGRMM-UHFFFAOYSA-N 0.000 claims description 3
- 239000007864 aqueous solution Substances 0.000 claims description 3
- 239000001768 carboxy methyl cellulose Substances 0.000 claims description 3
- 235000019812 sodium carboxymethyl cellulose Nutrition 0.000 claims description 3
- 229920001027 sodium carboxymethylcellulose Polymers 0.000 claims description 3
- 229920003174 cellulose-based polymer Polymers 0.000 claims description 2
- 239000003826 tablet Substances 0.000 description 47
- 239000000843 powder Substances 0.000 description 26
- 238000009472 formulation Methods 0.000 description 22
- 239000004615 ingredient Substances 0.000 description 11
- 239000007788 liquid Substances 0.000 description 10
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 9
- 230000007547 defect Effects 0.000 description 9
- 239000000725 suspension Substances 0.000 description 9
- 229920002245 Dextrose equivalent Polymers 0.000 description 8
- 239000000853 adhesive Substances 0.000 description 8
- 230000001070 adhesive effect Effects 0.000 description 8
- 230000000052 comparative effect Effects 0.000 description 8
- 238000002156 mixing Methods 0.000 description 8
- 238000002360 preparation method Methods 0.000 description 7
- 239000002552 dosage form Substances 0.000 description 6
- 239000000463 material Substances 0.000 description 6
- 235000016709 nutrition Nutrition 0.000 description 6
- 230000008569 process Effects 0.000 description 6
- 238000003756 stirring Methods 0.000 description 5
- GWEVSGVZZGPLCZ-UHFFFAOYSA-N Titan oxide Chemical compound O=[Ti]=O GWEVSGVZZGPLCZ-UHFFFAOYSA-N 0.000 description 4
- 235000011187 glycerol Nutrition 0.000 description 4
- -1 glycerol ester Chemical class 0.000 description 4
- 229920000578 graft copolymer Polymers 0.000 description 4
- 239000000178 monomer Substances 0.000 description 4
- 239000000902 placebo Substances 0.000 description 4
- 229940068196 placebo Drugs 0.000 description 4
- 230000009747 swallowing Effects 0.000 description 4
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 3
- 239000002775 capsule Substances 0.000 description 3
- 239000008199 coating composition Substances 0.000 description 3
- 239000003086 colorant Substances 0.000 description 3
- 230000003247 decreasing effect Effects 0.000 description 3
- 239000008240 homogeneous mixture Substances 0.000 description 3
- 239000000243 solution Substances 0.000 description 3
- 239000007921 spray Substances 0.000 description 3
- 230000004584 weight gain Effects 0.000 description 3
- 235000019786 weight gain Nutrition 0.000 description 3
- PNEYBMLMFCGWSK-UHFFFAOYSA-N Alumina Chemical compound [O-2].[O-2].[O-2].[Al+3].[Al+3] PNEYBMLMFCGWSK-UHFFFAOYSA-N 0.000 description 2
- 102100030356 Arginase-2, mitochondrial Human genes 0.000 description 2
- 101000792835 Homo sapiens Arginase-2, mitochondrial Proteins 0.000 description 2
- UQSXHKLRYXJYBZ-UHFFFAOYSA-N Iron oxide Chemical compound [Fe]=O UQSXHKLRYXJYBZ-UHFFFAOYSA-N 0.000 description 2
- 238000009825 accumulation Methods 0.000 description 2
- 230000002776 aggregation Effects 0.000 description 2
- 230000005587 bubbling Effects 0.000 description 2
- 238000007906 compression Methods 0.000 description 2
- 230000006835 compression Effects 0.000 description 2
- 230000007423 decrease Effects 0.000 description 2
- 239000008121 dextrose Substances 0.000 description 2
- 239000003814 drug Substances 0.000 description 2
- 238000001035 drying Methods 0.000 description 2
- 238000005516 engineering process Methods 0.000 description 2
- 235000013305 food Nutrition 0.000 description 2
- 230000037406 food intake Effects 0.000 description 2
- 238000005469 granulation Methods 0.000 description 2
- 230000003179 granulation Effects 0.000 description 2
- 239000002932 luster Substances 0.000 description 2
- 238000012986 modification Methods 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- 239000000825 pharmaceutical preparation Substances 0.000 description 2
- 229940127557 pharmaceutical product Drugs 0.000 description 2
- 230000009467 reduction Effects 0.000 description 2
- 239000004094 surface-active agent Substances 0.000 description 2
- 238000009492 tablet coating Methods 0.000 description 2
- 239000002700 tablet coating Substances 0.000 description 2
- 229940033134 talc Drugs 0.000 description 2
- 235000012222 talc Nutrition 0.000 description 2
- 239000004408 titanium dioxide Substances 0.000 description 2
- URAYPUMNDPQOKB-UHFFFAOYSA-N triacetin Chemical compound CC(=O)OCC(OC(C)=O)COC(C)=O URAYPUMNDPQOKB-UHFFFAOYSA-N 0.000 description 2
- 239000004480 active ingredient Substances 0.000 description 1
- 239000000654 additive Substances 0.000 description 1
- 239000002671 adjuvant Substances 0.000 description 1
- 238000005054 agglomeration Methods 0.000 description 1
- 238000004220 aggregation Methods 0.000 description 1
- 239000007900 aqueous suspension Substances 0.000 description 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 1
- 230000004888 barrier function Effects 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 229920002678 cellulose Polymers 0.000 description 1
- 239000001913 cellulose Substances 0.000 description 1
- 239000007891 compressed tablet Substances 0.000 description 1
- 235000009508 confectionery Nutrition 0.000 description 1
- 238000009792 diffusion process Methods 0.000 description 1
- 238000004090 dissolution Methods 0.000 description 1
- 238000007580 dry-mixing Methods 0.000 description 1
- 239000007941 film coated tablet Substances 0.000 description 1
- 238000005187 foaming Methods 0.000 description 1
- 235000003599 food sweetener Nutrition 0.000 description 1
- 210000001035 gastrointestinal tract Anatomy 0.000 description 1
- 239000008103 glucose Substances 0.000 description 1
- 125000005456 glyceride group Chemical group 0.000 description 1
- 235000013773 glyceryl triacetate Nutrition 0.000 description 1
- 239000001087 glyceryl triacetate Substances 0.000 description 1
- 229920001519 homopolymer Polymers 0.000 description 1
- 230000007062 hydrolysis Effects 0.000 description 1
- 238000006460 hydrolysis reaction Methods 0.000 description 1
- 230000006872 improvement Effects 0.000 description 1
- 238000005259 measurement Methods 0.000 description 1
- 229940057917 medium chain triglycerides Drugs 0.000 description 1
- 239000010445 mica Substances 0.000 description 1
- 229910052618 mica group Inorganic materials 0.000 description 1
- 239000011812 mixed powder Substances 0.000 description 1
- 239000008184 oral solid dosage form Substances 0.000 description 1
- 239000007935 oral tablet Substances 0.000 description 1
- 229940096978 oral tablet Drugs 0.000 description 1
- 229910052760 oxygen Inorganic materials 0.000 description 1
- 239000001301 oxygen Substances 0.000 description 1
- 239000002245 particle Substances 0.000 description 1
- 230000000704 physical effect Effects 0.000 description 1
- 229920006395 saturated elastomer Polymers 0.000 description 1
- 238000000926 separation method Methods 0.000 description 1
- 238000009491 slugging Methods 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 238000005507 spraying Methods 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
- 239000003765 sweetening agent Substances 0.000 description 1
- 229960005196 titanium dioxide Drugs 0.000 description 1
- 235000010215 titanium dioxide Nutrition 0.000 description 1
- 229960002622 triacetin Drugs 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/284—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
- A61K47/38—Cellulose; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/282—Organic compounds, e.g. fats
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/2853—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers, poly(lactide-co-glycolide)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
- A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Inorganic Chemistry (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Dispersion Chemistry (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662370944P | 2016-08-04 | 2016-08-04 | |
| US62/370,944 | 2016-08-04 | ||
| PCT/US2017/043923 WO2018026596A1 (en) | 2016-08-04 | 2017-07-26 | Easy to swallow coatings and substrates coated therewith |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2019523290A JP2019523290A (ja) | 2019-08-22 |
| JP2019523290A5 JP2019523290A5 (enExample) | 2020-08-06 |
| JP7041120B2 true JP7041120B2 (ja) | 2022-03-23 |
Family
ID=61071910
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019505520A Active JP7041120B2 (ja) | 2016-08-04 | 2017-07-26 | 飲み込み易い被膜及びそれにより被覆された基材 |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US10232045B2 (enExample) |
| EP (1) | EP3474824B1 (enExample) |
| JP (1) | JP7041120B2 (enExample) |
| KR (1) | KR102437953B1 (enExample) |
| CN (1) | CN109562076B (enExample) |
| AU (1) | AU2017307194B2 (enExample) |
| CA (1) | CA3031671C (enExample) |
| CO (1) | CO2019000756A2 (enExample) |
| MX (1) | MX377902B (enExample) |
| RU (1) | RU2753049C2 (enExample) |
| WO (1) | WO2018026596A1 (enExample) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP7564805B2 (ja) * | 2018-10-05 | 2024-10-09 | アイエスピー インヴェストメンツ エルエルシー | 水溶性セルロースエーテルを含有する平滑な高固形分フィルムコーティング組成物、その調製方法およびその使用方法 |
| JP7317940B2 (ja) * | 2019-03-04 | 2023-07-31 | 沢井製薬株式会社 | フィルムコーティング組成物及び固形製剤 |
| US11953458B2 (en) | 2019-03-14 | 2024-04-09 | Ecolab Usa Inc. | Systems and methods utilizing sensor surface functionalization |
| US12427092B2 (en) | 2020-11-05 | 2025-09-30 | Purosil LLC | Device and method for assisting pill swallowing |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2014074039A (ja) | 2010-03-31 | 2014-04-24 | Mochida Pharmaceut Co Ltd | 易服用性固形製剤 |
| WO2015112400A1 (en) | 2014-01-21 | 2015-07-30 | Bpsi Holdings, Llc | Immediate release film coatings containing medium chain glycerides and substrates coated therewith |
Family Cites Families (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4543370A (en) | 1979-11-29 | 1985-09-24 | Colorcon, Inc. | Dry edible film coating composition, method and coating form |
| DE3220434A1 (de) | 1982-05-29 | 1983-12-01 | Robert Bosch Gmbh, 7000 Stuttgart | Verfahren zur ueberwachung einer messgroesse |
| AU658565B2 (en) * | 1990-04-04 | 1995-04-27 | Berwind Pharmaceutical Services, Inc. | Aqueous maltodextrin and cellulosic polymer film coatings |
| US5114720A (en) * | 1990-12-27 | 1992-05-19 | American Cyanamid Company | Gelatin coated tablets and method for producing same |
| WO2001026633A1 (en) | 1999-10-11 | 2001-04-19 | Monsanto Company | Tablets coated with locust bean gum, guar gum or carrageenan gum |
| TW200602089A (en) * | 2004-06-07 | 2006-01-16 | Wyeth Corp | Sugar coatings and methods therefor |
| EP2044126B1 (en) * | 2006-07-20 | 2012-11-14 | Rhodia, Inc. | Method for making derivatized guar gum and derivatized guar gum made thereby |
| HUP0700826A3 (en) * | 2007-12-20 | 2010-03-29 | Richter Gedeon Nyrt | Coated tablet containing drospirenone and process for producing the same |
| US8722089B2 (en) * | 2008-02-19 | 2014-05-13 | Mcneil-Ppc, Inc. | Dip coated compositions containing a starch having a high amylose content |
| WO2010052727A1 (en) * | 2008-11-04 | 2010-05-14 | Ideal Cures Private Limited | High performance film coating compositions |
| US20100124568A1 (en) | 2008-11-20 | 2010-05-20 | Med-Eez, Inc | Pharmaceutical articles coated with lubricious coatings |
| TR201807532T4 (tr) * | 2009-08-28 | 2018-06-21 | Hercules Llc | Katı toz bileşiklerinden ince tabaka kaplama bileşimi. |
| EP2605760B1 (en) | 2010-08-18 | 2017-01-11 | Johnson & Johnson Consumer Inc. | Tablet sleeve for improved performance |
| RU2605299C2 (ru) | 2011-02-14 | 2016-12-20 | Дзе Проктер Энд Гэмбл Компани | Твердая единица дозирования в пленочной оболочке, содержащей мед |
| MX364346B (es) * | 2011-02-28 | 2019-04-23 | Rhodia Operations | Recubrimientos de semilla, composiciones de recubrimiento y métodos para uso. |
| CN102652738A (zh) * | 2011-03-03 | 2012-09-05 | 天津聚贤投资有限公司 | 便于吞咽的新型药物外包皮 |
| WO2012166474A1 (en) * | 2011-06-01 | 2012-12-06 | Fmc Corporation | Controlled release solid dose forms |
| US20130064889A1 (en) * | 2011-09-13 | 2013-03-14 | Aptapharma, Inc. | Tablet-in-tablet Palperidone Formulations and Methods for Production and Use Thereof |
| WO2013046453A1 (ja) * | 2011-09-30 | 2013-04-04 | 持田製薬株式会社 | 易服用性固形製剤 |
| CN102430124B (zh) * | 2011-11-24 | 2013-03-20 | 清华大学 | 一种具有超低摩擦系数的药丸涂层及其制备方法 |
| CN104274409B (zh) * | 2013-07-10 | 2017-11-03 | 北京科信必成医药科技发展有限公司 | 一种易于吞服的药物微球及其制备方法 |
| JP6294400B2 (ja) | 2016-07-19 | 2018-03-14 | 持田製薬株式会社 | 易服用性固形製剤 |
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| JP2014074039A (ja) | 2010-03-31 | 2014-04-24 | Mochida Pharmaceut Co Ltd | 易服用性固形製剤 |
| WO2015112400A1 (en) | 2014-01-21 | 2015-07-30 | Bpsi Holdings, Llc | Immediate release film coatings containing medium chain glycerides and substrates coated therewith |
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| RU2019105589A3 (enExample) | 2020-09-04 |
| CA3031671A1 (en) | 2018-02-08 |
| AU2017307194A1 (en) | 2019-01-24 |
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| US20180036413A1 (en) | 2018-02-08 |
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| BR112019002040A2 (pt) | 2019-05-07 |
| KR20190035745A (ko) | 2019-04-03 |
| CN109562076B (zh) | 2022-01-28 |
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| RU2753049C2 (ru) | 2021-08-11 |
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| CA3031671C (en) | 2024-10-29 |
| EP3474824A1 (en) | 2019-05-01 |
| EP3474824A4 (en) | 2019-07-31 |
| US10232045B2 (en) | 2019-03-19 |
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