CA3031671C - EASY-TO-SWALLOW COATINGS AND SUBSTRATES COATED WITH THESE - Google Patents

EASY-TO-SWALLOW COATINGS AND SUBSTRATES COATED WITH THESE

Info

Publication number
CA3031671C
CA3031671C CA3031671A CA3031671A CA3031671C CA 3031671 C CA3031671 C CA 3031671C CA 3031671 A CA3031671 A CA 3031671A CA 3031671 A CA3031671 A CA 3031671A CA 3031671 C CA3031671 C CA 3031671C
Authority
CA
Canada
Prior art keywords
composition
water
guar gum
weight
coefficient
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CA3031671A
Other languages
English (en)
French (fr)
Other versions
CA3031671A1 (en
Inventor
Jeffrey R. Gimbel
Daniel To
Jason Teckoe
Original Assignee
BPSI Holdings LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by BPSI Holdings LLC filed Critical BPSI Holdings LLC
Publication of CA3031671A1 publication Critical patent/CA3031671A1/en
Application granted granted Critical
Publication of CA3031671C publication Critical patent/CA3031671C/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38—Cellulose; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/282—Organic compounds, e.g. fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/284—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/2853—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers, poly(lactide-co-glycolide)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
    • A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Inorganic Chemistry (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Dispersion Chemistry (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Preparation (AREA)
CA3031671A 2016-08-04 2017-07-26 EASY-TO-SWALLOW COATINGS AND SUBSTRATES COATED WITH THESE Active CA3031671C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201662370944P 2016-08-04 2016-08-04
US62/370,944 2016-08-04
PCT/US2017/043923 WO2018026596A1 (en) 2016-08-04 2017-07-26 Easy to swallow coatings and substrates coated therewith

Publications (2)

Publication Number Publication Date
CA3031671A1 CA3031671A1 (en) 2018-02-08
CA3031671C true CA3031671C (en) 2024-10-29

Family

ID=61071910

Family Applications (1)

Application Number Title Priority Date Filing Date
CA3031671A Active CA3031671C (en) 2016-08-04 2017-07-26 EASY-TO-SWALLOW COATINGS AND SUBSTRATES COATED WITH THESE

Country Status (11)

Country Link
US (1) US10232045B2 (enExample)
EP (1) EP3474824B1 (enExample)
JP (1) JP7041120B2 (enExample)
KR (1) KR102437953B1 (enExample)
CN (1) CN109562076B (enExample)
AU (1) AU2017307194B2 (enExample)
CA (1) CA3031671C (enExample)
CO (1) CO2019000756A2 (enExample)
MX (1) MX377902B (enExample)
RU (1) RU2753049C2 (enExample)
WO (1) WO2018026596A1 (enExample)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3860849A4 (en) * 2018-10-05 2022-06-22 ISP Investments LLC SMOOTH HIGH SOLIDS FILM COATING COMPOSITION WITH WATER SOLUBLE CELLULOSE ETHER, PROCESS FOR ITS PRODUCTION
EP3936581A4 (en) * 2019-03-04 2022-11-30 Sawai Pharmaceutical Co., Ltd. FILM COATING COMPOSITION AND SOLID PREPARATION
US11953458B2 (en) 2019-03-14 2024-04-09 Ecolab Usa Inc. Systems and methods utilizing sensor surface functionalization
US12427092B2 (en) 2020-11-05 2025-09-30 Purosil LLC Device and method for assisting pill swallowing

Family Cites Families (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4543370A (en) 1979-11-29 1985-09-24 Colorcon, Inc. Dry edible film coating composition, method and coating form
DE3220434A1 (de) 1982-05-29 1983-12-01 Robert Bosch Gmbh, 7000 Stuttgart Verfahren zur ueberwachung einer messgroesse
DK0527153T3 (da) 1990-04-04 1996-11-25 Berwind Pharma Service Vandige filmovertræk af maltodextrin og cellulosepolymerer
US5114720A (en) * 1990-12-27 1992-05-19 American Cyanamid Company Gelatin coated tablets and method for producing same
WO2001026633A1 (en) 1999-10-11 2001-04-19 Monsanto Company Tablets coated with locust bean gum, guar gum or carrageenan gum
BRPI0511663A (pt) * 2004-06-07 2008-01-02 Wyeth Corp composição compreendendo água e um componente de sólidos, processo, e, tablete revestido
WO2008011187A2 (en) * 2006-07-20 2008-01-24 Rhodia Inc. Method for making derivatized guar gum and derivatized guar gum made thereby
HUP0700826A3 (en) * 2007-12-20 2010-03-29 Richter Gedeon Nyrt Coated tablet containing drospirenone and process for producing the same
EP2252271B1 (en) * 2008-02-19 2012-05-23 McNeil-PPC, Inc. Dip coated compositions containing a starch having a high amylose content
WO2010052727A1 (en) * 2008-11-04 2010-05-14 Ideal Cures Private Limited High performance film coating compositions
US20100124568A1 (en) 2008-11-20 2010-05-20 Med-Eez, Inc Pharmaceutical articles coated with lubricious coatings
JP5795585B2 (ja) * 2009-08-28 2015-10-14 ハーキュリーズ・インコーポレーテッドＨｅｒｃｕｌｅｓ Ｉｎｃｏｒｐｏｒａｔｅｄ 固体粉末化合物からのフィルムコーティング組成物
CA2788732C (en) * 2010-03-31 2017-08-15 Yumio Kudou Easily dosable solid preparation
BR112013003762A2 (pt) 2010-08-18 2016-05-31 Mcneil Ppc Inc invólucro de comprimido para aprimorar o desempenho
EP2675437B1 (en) * 2011-02-14 2018-01-24 The Procter and Gamble Company Filmcoated solid dosage forms comprising honey in the coating
CN103391710B (zh) * 2011-02-28 2015-04-29 罗地亚管理公司 种子包衣、包衣组合物及其使用方法
CN102652738A (zh) * 2011-03-03 2012-09-05 天津聚贤投资有限公司 便于吞咽的新型药物外包皮
CA2837077A1 (en) * 2011-06-01 2012-12-06 Fmc Corporation Controlled release solid dose forms
US20130064889A1 (en) * 2011-09-13 2013-03-14 Aptapharma, Inc. Tablet-in-tablet Palperidone Formulations and Methods for Production and Use Thereof
CN107049979B (zh) * 2011-09-30 2020-08-14 持田制药株式会社 易服用性固体制剂
CN102430124B (zh) * 2011-11-24 2013-03-20 清华大学 一种具有超低摩擦系数的药丸涂层及其制备方法
CN104274409B (zh) * 2013-07-10 2017-11-03 北京科信必成医药科技发展有限公司 一种易于吞服的药物微球及其制备方法
MX378845B (es) * 2014-01-21 2025-03-10 Bpsi Holdings Llc Revestimientos de pelicula de liberacion inmediata que contienen gliceridos de cadena media y sustratos revestidos con los mismos.
JP6294400B2 (ja) * 2016-07-19 2018-03-14 持田製薬株式会社 易服用性固形製剤

Also Published As

Publication number Publication date
RU2019105589A3 (enExample) 2020-09-04
EP3474824A1 (en) 2019-05-01
BR112019002040A2 (pt) 2019-05-07
RU2019105589A (ru) 2020-09-04
US20180036413A1 (en) 2018-02-08
JP7041120B2 (ja) 2022-03-23
MX377902B (es) 2025-03-10
WO2018026596A1 (en) 2018-02-08
US10232045B2 (en) 2019-03-19
JP2019523290A (ja) 2019-08-22
MX2019001238A (es) 2019-04-25
RU2753049C2 (ru) 2021-08-11
KR20190035745A (ko) 2019-04-03
EP3474824B1 (en) 2022-02-16
CO2019000756A2 (es) 2019-02-08
AU2017307194A1 (en) 2019-01-24
CN109562076A (zh) 2019-04-02
CA3031671A1 (en) 2018-02-08
AU2017307194B2 (en) 2022-06-23
KR102437953B1 (ko) 2022-08-29
CN109562076B (zh) 2022-01-28
EP3474824A4 (en) 2019-07-31

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