BR112019002040A2 - revestimentos fáceis de engolir e substratos revestidos com os mesmos - Google Patents

revestimentos fáceis de engolir e substratos revestidos com os mesmos

Info

Publication number
BR112019002040A2
BR112019002040A2 BR112019002040A BR112019002040A BR112019002040A2 BR 112019002040 A2 BR112019002040 A2 BR 112019002040A2 BR 112019002040 A BR112019002040 A BR 112019002040A BR 112019002040 A BR112019002040 A BR 112019002040A BR 112019002040 A2 BR112019002040 A2 BR 112019002040A2
Authority
BR
Brazil
Prior art keywords
film coating
swallow
coating compositions
substrate
coatings
Prior art date
Application number
BR112019002040A
Other languages
English (en)
Inventor
To Daniel
Teckoe Jason
R Gimbel Jeffrey
Original Assignee
Bpsi Holdings Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bpsi Holdings Llc filed Critical Bpsi Holdings Llc
Publication of BR112019002040A2 publication Critical patent/BR112019002040A2/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38—Cellulose; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/282—Organic compounds, e.g. fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/284—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/2853—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers, poly(lactide-co-glycolide)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
    • A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Inorganic Chemistry (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Dispersion Chemistry (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Preparation (AREA)

Abstract

a presente invenção refere-se a composições de revestimento de película para o uso em formas de dosagem oral tais como comprimidos prensados e outros substratos oralmente ingeríveis que contêm um polímero solúvel em água e goma guar. as composições de revestimento de película podem ser aplicadas seja diretamente a um substrato ou após o substrato ter sido revestido de um sub-revestimento. em aspectos preferidos, o polímero solúvel em água é um polímero celulósico ou de vinila. as suspensões aquosas contendo as composições de revestimento de película da invenção e os substratos revestidos deles mesmos também são descritos. os substratos revestidos resultantes têm coeficientes relativamente baixos de fricção estática e dinâmica em superfícies úmidas tornando-os mais fáceis de engolir do que as composições do estado da técnica.
BR112019002040A 2016-08-04 2017-07-26 revestimentos fáceis de engolir e substratos revestidos com os mesmos BR112019002040A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201662370944P 2016-08-04 2016-08-04
PCT/US2017/043923 WO2018026596A1 (en) 2016-08-04 2017-07-26 Easy to swallow coatings and substrates coated therewith

Publications (1)

Publication Number Publication Date
BR112019002040A2 true BR112019002040A2 (pt) 2019-05-07

Family

ID=61071910

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112019002040A BR112019002040A2 (pt) 2016-08-04 2017-07-26 revestimentos fáceis de engolir e substratos revestidos com os mesmos

Country Status (12)

Country Link
US (1) US10232045B2 (pt)
EP (1) EP3474824B1 (pt)
JP (1) JP7041120B2 (pt)
KR (1) KR102437953B1 (pt)
CN (1) CN109562076B (pt)
AU (1) AU2017307194B2 (pt)
BR (1) BR112019002040A2 (pt)
CA (1) CA3031671A1 (pt)
CO (1) CO2019000756A2 (pt)
MX (1) MX2019001238A (pt)
RU (1) RU2753049C2 (pt)
WO (1) WO2018026596A1 (pt)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2022504333A (ja) * 2018-10-05 2022-01-13 アイエスピー インヴェストメンツ エルエルシー 水溶性セルロースエーテルを含有する平滑な高固形分フィルムコーティング組成物、その調製方法およびその使用方法
KR20210118164A (ko) * 2019-03-04 2021-09-29 사와이세이야쿠 가부시키가이샤 필름 코팅 조성물 및 고형 제제

Family Cites Families (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4543370A (en) 1979-11-29 1985-09-24 Colorcon, Inc. Dry edible film coating composition, method and coating form
DE3220434A1 (de) 1982-05-29 1983-12-01 Robert Bosch Gmbh, 7000 Stuttgart Verfahren zur ueberwachung einer messgroesse
EP0527153B1 (en) * 1990-04-04 1996-07-24 Berwind Pharmaceutical Services, Inc. Aqueous maltodextrin and cellulosic polymer film coatings
US5114720A (en) * 1990-12-27 1992-05-19 American Cyanamid Company Gelatin coated tablets and method for producing same
WO2001026633A1 (en) 1999-10-11 2001-04-19 Monsanto Company Tablets coated with locust bean gum, guar gum or carrageenan gum
CA2566771A1 (en) * 2004-06-07 2005-12-22 Wyeth Sugar coatings and methods therefor
WO2008011187A2 (en) 2006-07-20 2008-01-24 Rhodia Inc. Method for making derivatized guar gum and derivatized guar gum made thereby
HUP0700826A3 (en) * 2007-12-20 2010-03-29 Richter Gedeon Nyrt Coated tablet containing drospirenone and process for producing the same
KR20100129740A (ko) * 2008-02-19 2010-12-09 맥네일-피피씨, 인코포레이티드 아밀로스 함량이 높은 전분을 포함하는 침지 코팅 조성물
WO2010052727A1 (en) * 2008-11-04 2010-05-14 Ideal Cures Private Limited High performance film coating compositions
US20100124568A1 (en) 2008-11-20 2010-05-20 Med-Eez, Inc Pharmaceutical articles coated with lubricious coatings
US8968456B2 (en) * 2009-08-28 2015-03-03 Hercules Incorporated Film coating composition from solid powder hydrophobic compounds
CN104258408B (zh) * 2010-03-31 2017-10-03 持田制药株式会社 易服用性固体制剂
EP2605760B1 (en) 2010-08-18 2017-01-11 Johnson & Johnson Consumer Inc. Tablet sleeve for improved performance
MX352192B (es) 2011-02-14 2017-11-10 Procter & Gamble Formas de dosificación sólidas que comprenden miel en el recubrimiento.
AU2012223522B2 (en) * 2011-02-28 2017-01-19 Specialty Operations France Seed coatings, coating compositions and methods for use
CN102652738A (zh) * 2011-03-03 2012-09-05 天津聚贤投资有限公司 便于吞咽的新型药物外包皮
DK2714015T3 (en) * 2011-06-01 2017-06-19 Fmc Corp Fixed controlled release dosage forms
US20130064889A1 (en) * 2011-09-13 2013-03-14 Aptapharma, Inc. Tablet-in-tablet Palperidone Formulations and Methods for Production and Use Thereof
CA2847614C (en) * 2011-09-30 2018-10-23 Mochida Pharmaceutical Co., Ltd. Easily dosable solid preparation
CN102430124B (zh) * 2011-11-24 2013-03-20 清华大学 一种具有超低摩擦系数的药丸涂层及其制备方法
CN104274409B (zh) * 2013-07-10 2017-11-03 北京科信必成医药科技发展有限公司 一种易于吞服的药物微球及其制备方法
CA2933202C (en) 2014-01-21 2022-05-31 Jason Teckoe Immediate release film coatings containing medium chain glycerides and substrates coated therewith
JP6294400B2 (ja) 2016-07-19 2018-03-14 持田製薬株式会社 易服用性固形製剤

Also Published As

Publication number Publication date
AU2017307194A1 (en) 2019-01-24
KR102437953B1 (ko) 2022-08-29
RU2019105589A3 (pt) 2020-09-04
JP2019523290A (ja) 2019-08-22
AU2017307194B2 (en) 2022-06-23
CO2019000756A2 (es) 2019-02-08
WO2018026596A1 (en) 2018-02-08
CN109562076B (zh) 2022-01-28
KR20190035745A (ko) 2019-04-03
RU2753049C2 (ru) 2021-08-11
EP3474824A1 (en) 2019-05-01
JP7041120B2 (ja) 2022-03-23
RU2019105589A (ru) 2020-09-04
EP3474824B1 (en) 2022-02-16
MX2019001238A (es) 2019-04-25
US10232045B2 (en) 2019-03-19
US20180036413A1 (en) 2018-02-08
CN109562076A (zh) 2019-04-02
CA3031671A1 (en) 2018-02-08
EP3474824A4 (en) 2019-07-31

Similar Documents

Publication Publication Date Title
BR112015020836A2 (pt) revestimentos de filme de liberação retardada que contêm silicato de cálcio e substratos revestidos com os mesmos
BRPI0407518A (pt) sistemas de revestimento de pelìcula perolada e substratos revestidos por eles
BR112015025015A2 (pt) composições de formação de película para o revestimento com película de formas sólidas
BR112018007933A2 (pt) método para produzir película de revestimento
BRPI1007724A2 (pt) Composição de revestimento seco, suspensão aquosa, substrato oral, método para preparação de dispersão aquosa de revestimento, forma de dosagem oral farmaceuticamente aceitável e método de preparação de formas de dosagem sólidas orais farmaceuticamente aceitáveis
BR112014010355A2 (pt) composição de revestimento, método para o revestimento de um substrato, substrato revestido, material de embalagem e pacote líquido
BRPI1009244A2 (pt) processo de revestimento de matriz em fenda
BR112018068684A2 (pt) uso de resinas modificadas com ácidos graxos para conferir propriedade antidedadas a uma folha de vidro
MX2010005159A (es) Formulacion de recubrimiento enterico dispersable en agua para formas de dosificacion nutraceuticas y farmaceuticas.
BR112015009871A2 (pt) composições farmacêuticas compreendendo hidromorfona e naloxona
AR108512A1 (es) Apuntalantes autosuspendibles tolerantes a las sales y proceso para fabricar el mismo
BR112015030140A2 (pt) forma de dosagem farmacêutica sólida para liberação de pelo menos um ingrediente farmacêutico ativo na cavidade oral
BR112019002040A2 (pt) revestimentos fáceis de engolir e substratos revestidos com os mesmos
BR112017013598A2 (pt) composições de revestimento de película entérico, método de revestimento, e formas revestidas
BR112014032793A2 (pt) métodos e meios para revestimento de papel por revestimento de película
MX2016008583A (es) Revestimientos de pelicula de liberacion inmediata que contienen gliceridos de cadena media y sustratos revestidos con los mismos.
BR112018010984A2 (pt) ?composição para uma substância de queratina e processo cosmético?
WO2018192908A3 (en) COATING AND COATING PREPARATION
BR112017026202A2 (pt) composição modificadora da reologia seca, método de preparação da composição modificadora da reologia seca, formulação de produto e método de preparação de formulação
BR112022012378A2 (pt) Um método de preparar filme de celulose que compreende celulose microfibrilada
BR112019007744A2 (pt) composição de revestimento aquosa, e, métodos de preparação da composição de revestimento aquosa e de concessão de estabilidade de congelamento e descongelamento a um polímero de emulsão acrílica.
PH12017501363B1 (en) Procedure for preparing enteric-coated pellets containing a proton pump inhibitor and multi-particle pharmaceutical compositions containing them
MX2019003010A (es) Composición farmacéutica de clozapina de liberación prolongada.
BR112014030160A2 (pt) composição formadora de película, uso de uma composição formadora de película, película e cápsula dura
BR112014010116A2 (pt) métodos para a aplicação de um revestimento a um substrato em forma cilíndrica

Legal Events

Date Code Title Description
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]

Free format text: DE ACORDO COM O ARTIGO 229-C DA LEI NO 10196/2001, QUE MODIFICOU A LEI NO 9279/96, A CONCESSAO DA PATENTE ESTA CONDICIONADA A ANUENCIA PREVIA DA ANVISA. CONSIDERANDO A APROVACAO DOS TERMOS DO PARECER NO 337/PGF/EA/2010, BEM COMO A PORTARIA INTERMINISTERIAL NO 1065 DE 24/05/2012, ENCAMINHA-SE O PRESENTE PEDIDO PARA AS PROVIDENCIAS CABIVEIS.

B07G Grant request does not fulfill article 229-c lpi (prior consent of anvisa) [chapter 7.7 patent gazette]

Free format text: NOTIFICACAO DE DEVOLUCAO DO PEDIDO EM FUNCAO DA REVOGACAO DO ART. 229-C DA LEI NO 9.279, DE 1996, POR FORCA DA LEI NO 14.195, DE 2021

B06W Patent application suspended after preliminary examination (for patents with searches from other patent authorities) chapter 6.23 patent gazette]
B350 Update of information on the portal [chapter 15.35 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 26/07/2017, OBSERVADAS AS CONDICOES LEGAIS