JP7033549B2 - 細胞に基づくネオ抗原ワクチンおよびその使用 - Google Patents
細胞に基づくネオ抗原ワクチンおよびその使用 Download PDFInfo
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| KR102523318B1 (ko) | 2016-12-16 | 2023-04-18 | 비-모젠 바이오테크놀로지스, 인크. | 증진된 hAT 패밀리 트랜스포존 매개 유전자 전달 및 연관된 조성물, 시스템, 및 방법 |
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| CA3062591A1 (en) | 2017-05-08 | 2018-11-15 | Gritstone Oncology, Inc. | Alphavirus neoantigen vectors |
| WO2019086711A1 (en) * | 2017-11-06 | 2019-05-09 | Ludwig Institute For Cancer Research Ltd | Method for expansion of lymphocytes |
| EP3706770A4 (en) * | 2017-11-07 | 2021-10-27 | Nektar Therapeutics | IMMUNOTHERAPEUTIC COMBINATION FOR THE TREATMENT OF CANCER |
| EP3743083A4 (en) * | 2018-01-23 | 2021-11-03 | Vanderbilt University | SELF-ANTIGEN SPECIFIC T-LYMPHOCYTES AS VACCINES TO INCREASE ENGINEERING AND STABILITY OF AUTOLOGOUS TRANSFER |
| WO2019173441A1 (en) * | 2018-03-06 | 2019-09-12 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Methods of preparing populations of cells and retroviral reagents for adoptive cell immunotherapy |
| EP3781678A4 (en) * | 2018-04-18 | 2022-06-01 | Yale University | Compositions and methods for multiplexed tumor vaccination with endogenous gene activation |
| WO2020036646A2 (en) * | 2018-04-25 | 2020-02-20 | The Methodist Hospital System | Cancer neoantigens and their utilities in cancer vaccines and tcr-based cancer immunotherapy |
| TW202000906A (zh) * | 2018-05-23 | 2020-01-01 | 美商葛利史東腫瘤科技公司 | 免疫檢查點抑制劑共表現載體 |
| MX2020012649A (es) * | 2018-05-25 | 2021-07-02 | The Wistar Inst | Neoantígenos especificos de tumor y métodos de uso de estos. |
| EP3810764A2 (en) | 2018-06-21 | 2021-04-28 | B-Mogen Biotechnologies, Inc. | Enhanced hat family transposon-mediated gene transfer and associated compositions, systems, and methods |
| JP2021534752A (ja) | 2018-08-22 | 2021-12-16 | フレッド ハッチンソン キャンサー リサーチ センター | Kras抗原またはher2抗原を標的とする免疫療法 |
| WO2020097530A2 (en) | 2018-11-09 | 2020-05-14 | Fred Hutchinson Cancer Research Center | Immunotherapy targeting mesothelin |
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| GB2596461B (en) | 2019-02-20 | 2023-09-27 | Fred Hutchinson Cancer Center | Binding proteins specific for RAS neoantigens and uses thereof |
| MX2021014525A (es) | 2019-05-30 | 2022-03-17 | Gritstone Bio Inc | Adenovirus modificados. |
| WO2020252404A1 (en) | 2019-06-12 | 2020-12-17 | Obsidian Therapeutics, Inc. | Ca2 compositions and methods for tunable regulation |
| WO2021043804A1 (en) * | 2019-09-02 | 2021-03-11 | Institut Curie | Immunotherapy targeting tumor neoantigenic peptides |
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| WO2022067038A1 (en) * | 2020-09-25 | 2022-03-31 | President And Fellows Of Harvard College | Immunotherapeutic virus for the treatment of cancer |
| AR124826A1 (es) * | 2021-02-08 | 2023-05-10 | Hutchinson Fred Cancer Res | Sistema y métodos para vincular la señalización de cd40 a la unión del antígeno |
| WO2023173116A1 (en) * | 2022-03-10 | 2023-09-14 | City Of Hope | Membrane-bound il-12 for cellular immunotherapy |
| WO2024118634A2 (en) * | 2022-11-28 | 2024-06-06 | The Trustees Of The University Of Pennsylvania | In vivo expansion of car t cells and delivery of car target antigen to tumors using mrna lipid nanoparticles |
| CN117338914B (zh) * | 2023-10-27 | 2024-09-06 | 中山市珈钰生物医药有限公司 | 一种同种异体树突细胞肿瘤疫苗及其制备方法和应用 |
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| CN119823283B (zh) * | 2025-01-08 | 2025-08-26 | 国科明耀(山东)医学科技有限公司 | 一种il-12-cd137嵌合蛋白、一种功能增强型工程化nk细胞、其制备及应用 |
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| US11723962B2 (en) | 2023-08-15 |
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| CA3022267A1 (en) | 2017-11-09 |
| JP2019514393A (ja) | 2019-06-06 |
| JP2022091750A (ja) | 2022-06-21 |
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