JP6983994B2 - 注射ペン上の投与量測定モジュール - Google Patents
注射ペン上の投与量測定モジュール Download PDFInfo
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
- A61M5/31566—Means improving security or handling thereof
- A61M5/31568—Means keeping track of the total dose administered, e.g. since the cartridge was inserted
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31533—Dosing mechanisms, i.e. setting a dose
- A61M5/31545—Setting modes for dosing
- A61M5/31546—Electrically operated dose setting, e.g. input via touch screen or plus/minus buttons
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31533—Dosing mechanisms, i.e. setting a dose
- A61M5/31535—Means improving security or handling thereof, e.g. blocking means, means preventing insufficient dosing, means allowing correction of overset dose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
- A61M5/31576—Constructional features or modes of drive mechanisms for piston rods
- A61M5/31583—Constructional features or modes of drive mechanisms for piston rods based on rotational translation, i.e. movement of piston rod is caused by relative rotation between the user activated actuator and the piston rod
- A61M5/31585—Constructional features or modes of drive mechanisms for piston rods based on rotational translation, i.e. movement of piston rod is caused by relative rotation between the user activated actuator and the piston rod performed by axially moving actuator, e.g. an injection button
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
- A61M5/31576—Constructional features or modes of drive mechanisms for piston rods
- A61M2005/31588—Constructional features or modes of drive mechanisms for piston rods electrically driven
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/33—Controlling, regulating or measuring
- A61M2205/3306—Optical measuring means
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/33—Controlling, regulating or measuring
- A61M2205/3327—Measuring
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/50—General characteristics of the apparatus with microprocessors or computers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/50—General characteristics of the apparatus with microprocessors or computers
- A61M2205/52—General characteristics of the apparatus with microprocessors or computers with memories providing a history of measured variating parameters of apparatus or patient
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/142—Pressure infusion, e.g. using pumps
- A61M5/14244—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body
- A61M5/14248—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body of the skin patch type
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31525—Dosing
- A61M5/31528—Dosing by means of rotational movements, e.g. screw-thread mechanisms
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
- A61M5/3159—Dose expelling manners
- A61M5/31593—Multi-dose, i.e. individually set dose repeatedly administered from the same medicament reservoir
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- Health & Medical Sciences (AREA)
- Vascular Medicine (AREA)
- Engineering & Computer Science (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
Description
Claims (23)
- 薬物送達装置であって、
装置本体と、
前記装置本体に取り付けられ、かつ用量設定中および用量送達中に回転軸の周りで前記装置本体に対して回転可能である、用量設定部材と、
前記用量設定部材に取り付けられ、かつ回転方向に関して前記用量設定部材に固定された、被検知素子であって、前記用量設定部材の前記回転軸の周りに半径方向に離間した交互の第1および第2の表面特徴部を含んでいる、被検知素子と、
前記装置本体に取り付けられたアクチュエータであって、前記アクチュエータが、用量設定中の第1の動作モードにおいて軸方向と回転方向に関して前記用量設定部材に固定されて、前記アクチュエータが、用量送達中の第2の動作モードにおいて前記装置本体に対して回転不能であり、前記被検知素子および前記用量設定部材が、送達される投与量に関して、用量送達中に前記アクチュエータに対して回転し、前記アクチュエータが前記第1の動作モードから前記第2のモードに向けて遠位に可動する、アクチュエータと、
用量送達中に前記アクチュエータに取り付けられた、回転センサであって、前記回転センサが、用量送達中に検知方向に検知光を放出する光源を含んでおり、前記回転センサが、用量送達中に前記検知方向に放出された前記検知光を受信するように位置付けられた、光センサをさらに含んでいる、回転センサとを含み、
前記交互の第1および第2の表面特徴部は、前記光源と前記光センサの間で受容されるように配置されており、
前記第1の動作モードにおいて、前記交互の第1および第2の表面特徴部は、前記光源と前記光センサから軸方向に変位して、
前記第2の動作モードにおいて、前記回転センサは、前記交互の第1および第2の表面特徴部が前記光源と前記光センサの間で受容されるように、前記アクチュエータが軸方向に遠位に移動することにより、前記被検知素子に対して軸方向に遠位に可動して、
前記第1および第2の表面特徴部を前記検知光の経路に位置決めする、用量送達中の前記被検知素子の回転であって、前記第1の表面特徴部が、前記光センサによって検出される前記検知光をもたらし、前記第2の表面特徴部が、前記光センサによって検出されない前記検知光をもたらし、前記回転センサが、前記検知光の前記検出または非検出に応答して、用量送達中の前記アクチュエータに対する前記用量設定部材の回転を検出する、回転と、
前記回転センサに応答して、用量送達中の前記アクチュエータに対する前記用量設定部材の前記検出された回転に基づいて前記用量送達の量を決定する、電子アセンブリと、を含む、薬物送達装置。 - 前記表面特徴部が、反射性表面および非反射性表面を含む、請求項1に記載の薬物送達装置。
- 前記表面特徴部が、前記被検知素子の交互の開口部分および閉鎖部分を含む、請求項1に記載の薬物送達装置。
- 前記表面特徴部が、交互の突起部および凹部を含む、請求項1に記載の薬物送達装置。
- 前記突起部が、軸方向に延在している、請求項4に記載の薬物送達装置。
- 光反射表面をさらに含んでおり、前記光センサが、前記光源によって放出され、かつ前記光反射表面によって反射される光を受信するように位置付けられている、請求項5に記載の薬物送達装置。
- 前記突起部が、前記用量設定部材から近位に延在している、請求項5に記載の薬物送達装置。
- 前記用量設定部材が、スカートである、請求項5に記載の薬物送達装置。
- 前記突起部が、半径方向に延在している、請求項4に記載の薬物送達装置。
- 前記光センサが、前記光源によって放出された光を直接的に受信するように位置付けられている、請求項9に記載の薬物送達装置。
- 前記突起部が、半径方向外向きに延在している、請求項9に記載の薬物送達装置。
- 前記用量設定部材が、用量ダイヤルである、請求項9に記載の薬物送達装置。
- 前記装置本体に取り外し可能に取り付けられたモジュールを含んでおり、前記モジュールが、前記回転センサおよび前記電子アセンブリを含んでいる、請求項1に記載の薬物送達装置。
- 前記モジュールが、前記アクチュエータに直接的に取り付けられている、請求項13に記載の薬物送達装置。
- 前記モジュールが、用量設定中または用量送達中に前記用量設定部材に直接的に取り付けられていない、請求項14に記載の薬物送達装置。
- 前記モジュールが、前記第1の動作モードから前記第2の動作モードまで軸方向に遠位に移動し、前記モジュールは、前記モジュールが前記第2の動作モードにあるときに、前記用量設定部材と接触することに応じて作動する、ウェイクアップスイッチを含む、請求項13に記載の薬物送達装置。
- 前記モジュールが、前記用量設定部材に直接的に取り付けられた連結構成要素を含んでおり、前記モジュールが、前記第2の動作モードで軸方向と回転方向に関して前記アクチュエータに固定されて、投与構成要素をさらに含んでいる、請求項13に記載の薬物送達装置。
- 前記投与構成要素が、用量設定中に前記アクチュエータに直接的に取り付けられていない、請求項17に記載の薬物送達装置。
- 前記投与構成要素が、用量設定中に、回転方向に関して前記連結構成要素に係止される、請求項17に記載の薬物送達装置。
- 前記モジュールが、前記第1の動作モードから前記第2の動作モードまで軸方向に遠位に移動する、請求項19に記載の薬物送達装置。
- 前記モジュールの前記第1の動作モードから前記第2の動作モードまでの移動が、回転方向に関する前記投与構成要素と前記連結構成要素との固定を解除する、請求項19に記載の薬物送達装置。
- 前記用量設定部材が、前記用量設定部材を前記装置本体に対して回転させる際に使用するための露出した円周面を含んでおり、前記投与構成要素が、内壁および外壁を含んでおり、前記連結構成要素が、前記内壁と前記外壁との間に受容された連結壁を含んでおり、前記連結構成要素が、前記内壁を越えて遠位に延在し、かつ前記用量設定部材の前記露出した円周面に取り付けられた連結部分を含んでいる、請求項17に記載の薬物送達装置。
- 薬物を含む、請求項1〜22のいずれか一項に記載の薬物送達装置。
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Application Number | Priority Date | Filing Date | Title |
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US201762547168P | 2017-08-18 | 2017-08-18 | |
US62/547,168 | 2017-08-18 | ||
PCT/US2018/046860 WO2019036576A1 (en) | 2017-08-18 | 2018-08-17 | DOSING MEASUREMENT MODULE ON INJECTION PEN |
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JP2020528306A JP2020528306A (ja) | 2020-09-24 |
JP2020528306A5 JP2020528306A5 (ja) | 2021-10-28 |
JP6983994B2 true JP6983994B2 (ja) | 2021-12-17 |
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JP2020502187A Active JP6983994B2 (ja) | 2017-08-18 | 2018-08-17 | 注射ペン上の投与量測定モジュール |
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US (2) | US11524117B2 (ja) |
EP (2) | EP4374894A2 (ja) |
JP (1) | JP6983994B2 (ja) |
AU (1) | AU2018318219B2 (ja) |
CA (1) | CA3073279C (ja) |
WO (1) | WO2019036576A1 (ja) |
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JP1631155S (ja) * | 2017-11-06 | 2019-05-13 | ||
EP3731901A1 (en) | 2017-11-23 | 2020-11-04 | Sanofi | Medicament injection device with rotary encoder |
US20200324055A1 (en) * | 2017-12-21 | 2020-10-15 | Sanofi | Apparatus for detecting activation of a drug delivery device |
USD903858S1 (en) | 2018-08-29 | 2020-12-01 | Eli Lilly And Company | Drug delivery device |
USD903857S1 (en) | 2018-08-29 | 2020-12-01 | Eli Lilly And Company | Component for a drug delivery device |
USD914199S1 (en) | 2018-08-29 | 2021-03-23 | Eli Lilly And Company | Component for a drug delivery device |
USD903105S1 (en) | 2018-08-29 | 2020-11-24 | Eli Lilly And Company | Component for a drug delivery device |
US20220118194A1 (en) * | 2019-02-27 | 2022-04-21 | Eli Lilly And Company | Medication delivery device with sensing system |
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US20230030744A1 (en) * | 2019-12-11 | 2023-02-02 | Sanofi | Modular system for a drug delivery device with electronic and corresponding modules and method |
WO2021116393A1 (en) | 2019-12-13 | 2021-06-17 | Sanofi | A wireless data communication circuitry for a drug delivery device |
CH715791A2 (de) * | 2020-03-26 | 2020-07-31 | Ypsomed Ag | Autoinjektor mit Aussschüttdetektion, Verfahren zu dessen Vorbereitung und Antriebseinheit dafür. |
CN117915974A (zh) * | 2021-09-24 | 2024-04-19 | 赛诺菲 | 编码器环、剂量记录系统以及具有其的药物递送装置 |
KR20240021558A (ko) * | 2022-08-10 | 2024-02-19 | 주식회사 오대 | 교체 편의성이 향상된 카트리지 및 이를 구비한 식모기 |
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CA3073279A1 (en) | 2019-02-21 |
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JP2020528306A (ja) | 2020-09-24 |
WO2019036576A1 (en) | 2019-02-21 |
AU2018318219A1 (en) | 2020-01-23 |
AU2018318219B2 (en) | 2021-07-15 |
CA3073279C (en) | 2023-08-15 |
US20230017492A1 (en) | 2023-01-19 |
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EP3668568A1 (en) | 2020-06-24 |
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