JP6946001B2 - 薬学的組成物、および１，２，４−オキサジアゾール安息香酸の塩 - Google Patents

薬学的組成物、および１，２，４−オキサジアゾール安息香酸の塩 Download PDF

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JP6946001B2
JP6946001B2 JP2016555713A JP2016555713A JP6946001B2 JP 6946001 B2 JP6946001 B2 JP 6946001B2 JP 2016555713 A JP2016555713 A JP 2016555713A JP 2016555713 A JP2016555713 A JP 2016555713A JP 6946001 B2 JP6946001 B2 JP 6946001B2
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salt
compound
eye
benzoic acid
oxadiazole
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Japanese (ja)
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JP2017507158A5 (https=
JP2017507158A (ja
Inventor
ダリ，マンダー，ブイ．
タカスギ，ジェイムス
ウィートール，マーラ，エル．
ウェルチ，エレン
Original Assignee
ピーティーシー セラピューティクス， インコーポレイテッド
ピーティーシー セラピューティクス， インコーポレイテッド
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Publication of JP2017507158A publication Critical patent/JP2017507158A/ja
Priority to JP2019211430A priority Critical patent/JP7335795B2/ja
Publication of JP2017507158A5 publication Critical patent/JP2017507158A5/ja
Priority to JP2021111631A priority patent/JP2021165299A/ja
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4245—Oxadiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/10—Ophthalmic agents for accommodation disorders, e.g. myopia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/12—Ophthalmic agents for cataracts
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D271/00—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms
    • C07D271/02—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms not condensed with other rings
    • C07D271/06—1,2,4-Oxadiazoles; Hydrogenated 1,2,4-oxadiazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13—Crystalline forms, e.g. polymorphs

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Ophthalmology & Optometry (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Medicinal Preparation (AREA)
JP2016555713A 2014-03-06 2015-03-05 薬学的組成物、および１，２，４−オキサジアゾール安息香酸の塩 Expired - Fee Related JP6946001B2 (ja)

Priority Applications (2)

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JP2019211430A JP7335795B2 (ja) 2014-03-06 2019-11-22 薬学的組成物、および１，２，４－オキサジアゾール安息香酸の塩
JP2021111631A JP2021165299A (ja) 2014-03-06 2021-07-05 薬学的組成物、および１，２，４−オキサジアゾール安息香酸の塩

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201461949052P 2014-03-06 2014-03-06
US61/949,052 2014-03-06
US201462009111P 2014-06-06 2014-06-06
US62/009,111 2014-06-06
PCT/US2015/018889 WO2015134711A1 (en) 2014-03-06 2015-03-05 Pharmaceutical compositions and salts of a 1,2,4-oxadiazole benzoic acid

Related Child Applications (2)

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JP2019211430A Division JP7335795B2 (ja) 2014-03-06 2019-11-22 薬学的組成物、および１，２，４－オキサジアゾール安息香酸の塩
JP2021111631A Division JP2021165299A (ja) 2014-03-06 2021-07-05 薬学的組成物、および１，２，４−オキサジアゾール安息香酸の塩

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JP2017507158A JP2017507158A (ja) 2017-03-16
JP2017507158A5 JP2017507158A5 (https=) 2020-01-30
JP6946001B2 true JP6946001B2 (ja) 2021-10-06

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JP2019211430A Active JP7335795B2 (ja) 2014-03-06 2019-11-22 薬学的組成物、および１，２，４－オキサジアゾール安息香酸の塩
JP2021111631A Ceased JP2021165299A (ja) 2014-03-06 2021-07-05 薬学的組成物、および１，２，４−オキサジアゾール安息香酸の塩

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JP2021111631A Ceased JP2021165299A (ja) 2014-03-06 2021-07-05 薬学的組成物、および１，２，４−オキサジアゾール安息香酸の塩

Country Status (10)

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US (3) US9873677B2 (https=)
EP (1) EP3113619A4 (https=)
JP (3) JP6946001B2 (https=)
KR (2) KR102497273B1 (https=)
CN (3) CN112979575A (https=)
CA (2) CA3174516A1 (https=)
EA (1) EA032779B1 (https=)
IL (1) IL247653B (https=)
TW (2) TWI636978B (https=)
WO (1) WO2015134711A1 (https=)

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JP2018531975A (ja) 2015-10-30 2018-11-01 ピーティーシー セラピューティクス，インコーポレーテッド てんかんの治療方法
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JP2020525434A (ja) 2017-06-22 2020-08-27 ムーンショット ファーマ エルエルシー アンレキサノクス及び免疫調節剤を含む組成物で癌を治療する方法
EP3713934B1 (en) 2017-11-23 2022-04-13 Universita' degli Studi di Palermo Oxadiazole derivatives for the treatment of genetic diseases due to nonsense mutations
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KR102497273B1 (ko) * 2014-03-06 2023-02-07 피티씨 테라퓨틱스, 인크. 1,2,4-옥사디아졸 벤조산의 약학 조성물 및 염
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CN112979574A (zh) 2021-06-18
IL247653A0 (en) 2016-11-30
US10233161B2 (en) 2019-03-19
KR102497273B1 (ko) 2023-02-07
TW201620883A (zh) 2016-06-16
CA3174516A1 (en) 2015-09-11
KR20230024431A (ko) 2023-02-20
US20190152931A1 (en) 2019-05-23
EP3113619A1 (en) 2017-01-11
TW201836605A (zh) 2018-10-16
US20180179170A1 (en) 2018-06-28
CN106455571A (zh) 2017-02-22
CA2942147A1 (en) 2015-09-11
EA032779B1 (ru) 2019-07-31
JP7335795B2 (ja) 2023-08-30
US10618877B2 (en) 2020-04-14
JP2021165299A (ja) 2021-10-14
JP2020045354A (ja) 2020-03-26
IL247653B (en) 2022-04-01
CN112979575A (zh) 2021-06-18
CA2942147C (en) 2022-12-13
EP3113619A4 (en) 2017-09-13
US20170066730A1 (en) 2017-03-09
KR20160122268A (ko) 2016-10-21
WO2015134711A1 (en) 2015-09-11
EA201691789A1 (ru) 2017-02-28
TWI636978B (zh) 2018-10-01
JP2017507158A (ja) 2017-03-16
TWI695717B (zh) 2020-06-11

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