JP6942789B2 - Ｃｈｒｉｍｓｏｎを用いた光遺伝学的視覚回復 - Google Patents

Ｃｈｒｉｍｓｏｎを用いた光遺伝学的視覚回復 Download PDF

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JP6942789B2
JP6942789B2 JP2019508309A JP2019508309A JP6942789B2 JP 6942789 B2 JP6942789 B2 JP 6942789B2 JP 2019508309 A JP2019508309 A JP 2019508309A JP 2019508309 A JP2019508309 A JP 2019508309A JP 6942789 B2 JP6942789 B2 JP 6942789B2
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protein
chrimson
tdt
cells
fused
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JP2019518073A5 (https=
JP2019518073A (ja
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ディディエ プリュノー
ディディエ プリュノー
アンヌ ドゥアール
アンヌ ドゥアール
デニズ ダルカラ
デニズ ダルカラ
イェンス ドゥーベル
イェンス ドゥーベル
ロマン キャプレット
ロマン キャプレット
グレゴリー ゴーヴァン
グレゴリー ゴーヴァン
メリッサ デロシアーズ
メリッサ デロシアーズ
ホセ サヘル
ホセ サヘル
セルジュ ピコー
セルジュ ピコー
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Centre National de la Recherche Scientifique CNRS
Sorbonne Universite
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Sorbonne Universite
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JP2019508309A 2016-04-29 2017-04-28 Ｃｈｒｉｍｓｏｎを用いた光遺伝学的視覚回復 Active JP6942789B2 (ja)

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US201662329692P 2016-04-29 2016-04-29
US62/329,692 2016-04-29
PCT/IB2017/000663 WO2017187272A1 (en) 2016-04-29 2017-04-28 Optogenetic visual restoration using chrimson

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JP2019518073A JP2019518073A (ja) 2019-06-27
JP2019518073A5 JP2019518073A5 (https=) 2020-05-07
JP6942789B2 true JP6942789B2 (ja) 2021-09-29

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US (2) US20190269755A1 (https=)
EP (1) EP3448411A1 (https=)
JP (1) JP6942789B2 (https=)
KR (1) KR102466887B1 (https=)
CN (1) CN110267673B (https=)
AU (2) AU2017256910B2 (https=)
CA (1) CA3025975A1 (https=)
WO (1) WO2017187272A1 (https=)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2016094850A1 (en) 2014-12-12 2016-06-16 The Trustees Of The University Of Pennsylvania Methods of Promoting Nervous System Regeneration
EP3442409A4 (en) 2016-04-14 2019-11-13 The Trustees of The University of Pennsylvania IMPLANTABLE LIVING ELECTRODES AND METHOD FOR USE THEREOF
EP3693061A1 (en) 2019-02-05 2020-08-12 Gensight Biologics Method for controlling an optogenetic device using filtering and associated devices
EP3693060A1 (en) 2019-02-05 2020-08-12 Gensight Biologics Method for controlling an optogenetic device using a command law for the radiant power of a light source and associated devices
EP3733139A1 (en) 2019-05-02 2020-11-04 Gensight Biologics Viewing apparatus and method for projecting a light signal
WO2021132903A1 (ko) * 2019-12-26 2021-07-01 고려대학교 산학협력단 광유전학 기법을 이용한 알츠하이머 질환 뇌에서의 뇌파 손상 회복 방법
US20250235585A1 (en) * 2022-02-18 2025-07-24 The Trustees Of The University Of Pennsylvania Tissue Engineered Spinal Tracts For Functional Regeneration After Spinal Cord Injury
EP4568710A1 (en) 2022-08-11 2025-06-18 Institute Of Molecular And Clinical Ophthalmology Basel (Iob) Human cone photoreceptor optogenetic constructs
CN119827471B (zh) * 2025-02-14 2025-10-03 中山大学中山眼科中心 一种体内追踪外段蛋白运输的方法

Family Cites Families (12)

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DE10216005A1 (de) 2002-04-11 2003-10-30 Max Planck Gesellschaft Verwendung von biologischen Photorezeptoren als direkt lichtgesteuerte Ionenkanäle
EP1919497B1 (en) 2005-07-22 2020-02-12 The Board of Trustees of the Leland Stanford Junior University Light-activated cation channel and uses thereof
CN101484005A (zh) * 2006-05-04 2009-07-15 韦恩州立大学 通过向体内递送视紫红质核酸恢复视觉响应
EP1891976A1 (en) 2006-08-23 2008-02-27 Novartis Forschungsstiftung, Zweigniederlassung Friedrich Miescher Institute for Biomedical Research Use of light sensitive genes
CN101980668A (zh) * 2008-02-07 2011-02-23 赛拉基因公司 通过玻璃体内施用编码治疗用蛋白质的表达载体救援光感器
MX2010011467A (es) 2008-04-18 2011-02-15 Novartis Forschungsstiftung Novedosas herramientas y metodos terapeuticos para tratar la ceguera.
CN105755044A (zh) 2011-04-22 2016-07-13 加利福尼亚大学董事会 具有变异衣壳的腺相关病毒病毒体及其使用方法
WO2013071231A1 (en) 2011-11-12 2013-05-16 Massachusetts Institute Of Technology Channelrhodopsins for optical control of cells
WO2015161308A1 (en) * 2014-04-18 2015-10-22 Massachusetts Institute Of Technology Mutant channelrhodopsins with altered ion selectivity
US10882892B2 (en) * 2014-08-05 2021-01-05 Massachusetts Institute Of Technology Channelrhodopsin variants and uses thereof
EP3371572B1 (en) * 2015-11-05 2021-05-05 Inscopix, Inc. System for optogenetic imaging
WO2017093566A1 (en) * 2015-12-04 2017-06-08 Universite Pierre Et Marie Curie (Paris 6) Promoters and uses thereof

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Publication number Publication date
AU2017256910B2 (en) 2022-04-07
US20190269755A1 (en) 2019-09-05
US20240165198A1 (en) 2024-05-23
KR20190058383A (ko) 2019-05-29
WO2017187272A8 (en) 2018-12-13
AU2017256910A1 (en) 2018-11-22
CN110267673B (zh) 2023-05-16
CN110267673A (zh) 2019-09-20
EP3448411A1 (en) 2019-03-06
CA3025975A1 (en) 2017-11-02
KR102466887B1 (ko) 2022-11-11
JP2019518073A (ja) 2019-06-27
AU2022204884A1 (en) 2022-07-28
WO2017187272A1 (en) 2017-11-02

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