JP6933659B2 - トリプルネガティブ乳癌の治療方法 - Google Patents

トリプルネガティブ乳癌の治療方法 Download PDF

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JP6933659B2
JP6933659B2 JP2018549164A JP2018549164A JP6933659B2 JP 6933659 B2 JP6933659 B2 JP 6933659B2 JP 2018549164 A JP2018549164 A JP 2018549164A JP 2018549164 A JP2018549164 A JP 2018549164A JP 6933659 B2 JP6933659 B2 JP 6933659B2
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taurolidine
patient
combination
administered
item
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JP2019508476A (ja
JP2019508476A5 (enExample
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レドモンド、エイチ・ポール
プフィルマン、ロルフ・ヴェ
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Geistlich Pharma AG
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Geistlich Pharma AG
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/541—Non-condensed thiazines containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/549—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame having two or more nitrogen atoms in the same ring, e.g. hydrochlorothiazide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/20—Interleukins [IL]
    • A61K38/2013—IL-2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
JP2018549164A 2016-03-18 2017-03-17 トリプルネガティブ乳癌の治療方法 Active JP6933659B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201662310275P 2016-03-18 2016-03-18
US62/310,275 2016-03-18
PCT/IB2017/051570 WO2017158570A1 (en) 2016-03-18 2017-03-17 Method of treating triple negative breast cancer

Publications (3)

Publication Number Publication Date
JP2019508476A JP2019508476A (ja) 2019-03-28
JP2019508476A5 JP2019508476A5 (enExample) 2019-05-23
JP6933659B2 true JP6933659B2 (ja) 2021-09-08

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ID=58410400

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JP2018549164A Active JP6933659B2 (ja) 2016-03-18 2017-03-17 トリプルネガティブ乳癌の治療方法

Country Status (6)

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US (1) US10736902B2 (enExample)
EP (1) EP3429614B1 (enExample)
JP (1) JP6933659B2 (enExample)
CA (1) CA3018145C (enExample)
ES (1) ES2945712T3 (enExample)
WO (1) WO2017158570A1 (enExample)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11591302B2 (en) 2014-12-19 2023-02-28 Geistlich Pharm A Ag Processes for preparing oxathiazin-like compounds
US20190381060A1 (en) 2016-01-11 2019-12-19 Cormedix Inc. Taurolidine treatment for myc-expressing tumors in mammalian bodies
US11865176B2 (en) 2016-11-08 2024-01-09 Dana-Farber Cancer Institute, Inc. Compositions and methods of modulating anti-tumor immunity
AU2019331913B2 (en) * 2018-08-31 2025-06-26 Cormedix Inc. Taurolidine treatment for myc-expressing tumors in mammalian bodies
CN114025766B (zh) * 2019-05-22 2024-09-10 盖斯特里希医药公司 用于抑制gapdh的噁噻嗪化合物
WO2020234830A1 (en) * 2019-05-22 2020-11-26 Geistlich Pharma Ag Oxathiazin_dioxide for treating, preventing, inhibiting or reducing cytokine release
CN114466657B (zh) * 2019-07-25 2024-11-15 芝加哥大学 包括蛋白酶激活治疗剂的组合物和方法
US20220218634A1 (en) * 2021-01-13 2022-07-14 Chengde SHANG Method for inducing mass apoptosis of cancer cells by enhancing the overall acidity in the tumor

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8617482D0 (en) 1986-07-17 1986-08-28 Geistlich Soehne Ag Pharmaceutical composition
CA2010511A1 (en) * 1989-03-01 1990-09-01 Roberto L. Ceriani Method of enhancing cancer therapy by administration of unsaturated fatty acids
US20020098164A1 (en) * 2000-10-27 2002-07-25 Redmond H. Paul Treatment of tumor metastases and cancer
US7892530B2 (en) 1999-06-04 2011-02-22 Ed. Geistlich Soehne Ag Fuer Chemische Industrie Treatment of tumor metastases and cancer
US20030092707A1 (en) * 2001-10-19 2003-05-15 Redmond H. Paul Treatment of breast cancer
PL2861573T3 (pl) 2012-06-18 2018-02-28 Geistlich Pharma Ag Pochodne oksatiazyny jako środki przeciwbakteryjne i przeciwnowotworowe
WO2015092614A1 (en) * 2013-12-20 2015-06-25 Pfizer Inc. Activating notch alterations in breast cancer

Also Published As

Publication number Publication date
CA3018145C (en) 2024-09-17
EP3429614B1 (en) 2023-05-03
US10736902B2 (en) 2020-08-11
US20190091233A1 (en) 2019-03-28
JP2019508476A (ja) 2019-03-28
ES2945712T3 (es) 2023-07-06
WO2017158570A1 (en) 2017-09-21
CA3018145A1 (en) 2017-09-21
EP3429614A1 (en) 2019-01-23

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