JP6913026B2 - インターロイキン36受容体(il−36r)に対する抗体 - Google Patents

インターロイキン36受容体(il−36r)に対する抗体 Download PDF

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JP6913026B2
JP6913026B2 JP2017553885A JP2017553885A JP6913026B2 JP 6913026 B2 JP6913026 B2 JP 6913026B2 JP 2017553885 A JP2017553885 A JP 2017553885A JP 2017553885 A JP2017553885 A JP 2017553885A JP 6913026 B2 JP6913026 B2 JP 6913026B2
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バウワーズ、ピーター
ジョン マックナイト、アンドリュー
ジョン マックナイト、アンドリュー
ジェイ. キング、デイヴィッド
ジェイ. キング、デイヴィッド
ロンデイ、マルコ
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アナプティスバイオ インコーポレイティッド
アナプティスバイオ インコーポレイティッド
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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2866Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/06Antipsoriatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/30Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/33Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/90Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value

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  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
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  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Rheumatology (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Transplantation (AREA)
  • Pain & Pain Management (AREA)
  • Microbiology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Dermatology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
JP2017553885A 2015-04-15 2016-04-15 インターロイキン36受容体(il−36r)に対する抗体 Active JP6913026B2 (ja)

Priority Applications (3)

Application Number Priority Date Filing Date Title
JP2021069306A JP7212098B2 (ja) 2015-04-15 2021-04-15 インターロイキン36受容体(il-36r)に対する抗体
JP2023003385A JP7721585B2 (ja) 2015-04-15 2023-01-12 インターロイキン36受容体(il-36r)に対する抗体
JP2025127775A JP2025163120A (ja) 2015-04-15 2025-07-30 インターロイキン36受容体(il-36r)に対する抗体

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562147824P 2015-04-15 2015-04-15
US62/147,824 2015-04-15
PCT/US2016/027676 WO2016168542A1 (en) 2015-04-15 2016-04-15 Antibodies directed against interleukin 36 receptor (il-36r)

Related Child Applications (1)

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JP2021069306A Division JP7212098B2 (ja) 2015-04-15 2021-04-15 インターロイキン36受容体(il-36r)に対する抗体

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JP2018512157A JP2018512157A (ja) 2018-05-17
JP2018512157A5 JP2018512157A5 (OSRAM) 2019-05-23
JP6913026B2 true JP6913026B2 (ja) 2021-08-04

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JP2017553885A Active JP6913026B2 (ja) 2015-04-15 2016-04-15 インターロイキン36受容体(il−36r)に対する抗体
JP2021069306A Active JP7212098B2 (ja) 2015-04-15 2021-04-15 インターロイキン36受容体(il-36r)に対する抗体
JP2023003385A Active JP7721585B2 (ja) 2015-04-15 2023-01-12 インターロイキン36受容体(il-36r)に対する抗体
JP2025127775A Pending JP2025163120A (ja) 2015-04-15 2025-07-30 インターロイキン36受容体(il-36r)に対する抗体

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JP2021069306A Active JP7212098B2 (ja) 2015-04-15 2021-04-15 インターロイキン36受容体(il-36r)に対する抗体
JP2023003385A Active JP7721585B2 (ja) 2015-04-15 2023-01-12 インターロイキン36受容体(il-36r)に対する抗体
JP2025127775A Pending JP2025163120A (ja) 2015-04-15 2025-07-30 インターロイキン36受容体(il-36r)に対する抗体

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US (3) US10526410B2 (OSRAM)
EP (2) EP4176900A1 (OSRAM)
JP (4) JP6913026B2 (OSRAM)
KR (1) KR102666920B1 (OSRAM)
CN (2) CN107847590B (OSRAM)
AU (1) AU2016248208B2 (OSRAM)
CA (1) CA2982555A1 (OSRAM)
DK (1) DK3283110T3 (OSRAM)
ES (1) ES2914243T3 (OSRAM)
MX (2) MX2017013080A (OSRAM)
PL (1) PL3283110T3 (OSRAM)
RU (1) RU2745898C2 (OSRAM)
SG (1) SG11201708061TA (OSRAM)
WO (1) WO2016168542A1 (OSRAM)

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CN116157151A (zh) 2020-05-26 2023-05-23 真和制药有限公司 通过阻断半乳凝素-3治疗炎性疾病的方法
EP4182022A1 (en) 2020-07-17 2023-05-24 Boehringer Ingelheim International GmbH Anti-il-36r antibodies for the treatment of neutrophilic dermatoses
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TW202302644A (zh) * 2021-03-04 2023-01-16 德商百靈佳殷格翰國際股份有限公司 治療gpp之方法
JP2024512384A (ja) 2021-03-12 2024-03-19 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング 汎発型膿疱性乾癬における抗il-36r抗体による処置に関連したバイオマーカー
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HK1252009A1 (zh) 2019-05-10
US20180094065A1 (en) 2018-04-05
JP7212098B2 (ja) 2023-01-24
US10526410B2 (en) 2020-01-07
CN107847590A (zh) 2018-03-27
US20200087408A1 (en) 2020-03-19
RU2745898C2 (ru) 2021-04-02
EP3283110A4 (en) 2019-02-27
JP2018512157A (ja) 2018-05-17
WO2016168542A1 (en) 2016-10-20
CN115925932A (zh) 2023-04-07
SG11201708061TA (en) 2017-10-30
RU2017139481A3 (OSRAM) 2019-09-19
KR102666920B1 (ko) 2024-05-20
CA2982555A1 (en) 2016-10-20
EP3283110A1 (en) 2018-02-21
EP3283110B1 (en) 2022-04-20
ES2914243T3 (es) 2022-06-08
KR20180002687A (ko) 2018-01-08
AU2016248208A1 (en) 2017-11-09
RU2017139481A (ru) 2019-05-15
JP7721585B2 (ja) 2025-08-12
US12391761B2 (en) 2025-08-19
JP2023040236A (ja) 2023-03-22
AU2016248208B2 (en) 2022-03-24
US11130814B2 (en) 2021-09-28
MX2023001791A (es) 2023-03-10
DK3283110T3 (da) 2022-05-23
CN107847590B (zh) 2022-07-26
EP4176900A1 (en) 2023-05-10
PL3283110T3 (pl) 2022-06-27
JP2021118710A (ja) 2021-08-12
JP2025163120A (ja) 2025-10-28
US20210388095A1 (en) 2021-12-16
MX2017013080A (es) 2018-02-09
HK1250941A1 (en) 2019-01-18
NZ736535A (en) 2024-08-30
BR112017022086A2 (pt) 2018-07-03

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