JP6898856B2 - 長時間作用型薬物送達装置および避妊におけるその使用 - Google Patents

長時間作用型薬物送達装置および避妊におけるその使用 Download PDF

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JP6898856B2
JP6898856B2 JP2017558678A JP2017558678A JP6898856B2 JP 6898856 B2 JP6898856 B2 JP 6898856B2 JP 2017558678 A JP2017558678 A JP 2017558678A JP 2017558678 A JP2017558678 A JP 2017558678A JP 6898856 B2 JP6898856 B2 JP 6898856B2
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drug
core
lng
release
membrane
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JP2018516889A (ja
JP2018516889A5 (cg-RX-API-DMAC10.html
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ホルムバリ，スヴァンテ
タールリング，クリスティーネ
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バイエル・オーイュー
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
    • A61K9/0036—Devices retained in the vagina or cervix for a prolonged period, e.g. intravaginal rings, medicated tampons, medicated diaphragms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/567—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in position 17 alpha, e.g. mestranol, norethandrolone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
    • A61K9/0039—Devices retained in the uterus for a prolonged period, e.g. intrauterine devices for contraception
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/12—Drugs for genital or sexual disorders; Contraceptives for climacteric disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/18—Feminine contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Reproductive Health (AREA)
  • Epidemiology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Urology & Nephrology (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Orthopedics, Nursing, And Contraception (AREA)
JP2017558678A 2015-05-13 2016-05-09 長時間作用型薬物送達装置および避妊におけるその使用 Active JP6898856B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP15167521 2015-05-13
EP15167521.2 2015-05-13
PCT/EP2016/060298 WO2016180764A1 (en) 2015-05-13 2016-05-09 A long acting drug delivery device and its use in contraception

Publications (3)

Publication Number Publication Date
JP2018516889A JP2018516889A (ja) 2018-06-28
JP2018516889A5 JP2018516889A5 (cg-RX-API-DMAC10.html) 2020-07-02
JP6898856B2 true JP6898856B2 (ja) 2021-07-07

Family

ID=53174913

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2017558678A Active JP6898856B2 (ja) 2015-05-13 2016-05-09 長時間作用型薬物送達装置および避妊におけるその使用

Country Status (8)

Country Link
US (3) US11096888B2 (cg-RX-API-DMAC10.html)
EP (1) EP3294300B1 (cg-RX-API-DMAC10.html)
JP (1) JP6898856B2 (cg-RX-API-DMAC10.html)
CN (1) CN108135910B (cg-RX-API-DMAC10.html)
CA (1) CA2985717A1 (cg-RX-API-DMAC10.html)
ES (1) ES3009909T3 (cg-RX-API-DMAC10.html)
FI (1) FI3294300T3 (cg-RX-API-DMAC10.html)
WO (1) WO2016180764A1 (cg-RX-API-DMAC10.html)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PE20211195A1 (es) * 2017-09-27 2021-07-01 Bayer Oy Un metodo para modificar la liberacion de un agente terapeuticamente activo de una matriz elastomerica
CA3087238A1 (en) 2018-05-24 2019-11-28 Celanese EVA Performance Polymers Corporation Implantable device for sustained release of a macromolecular drug compound
EP3803866A4 (en) 2018-05-24 2022-03-16 Nureva Inc. METHOD, APPARATUS, AND COMPUTER READABLE MATERIALS FOR MANAGING SEMI-CONSTANT (PERSISTENT) SOUND SOURCES IN MICROPHONE CATCH/HOME AREAS
CN111989068B (zh) 2018-05-24 2024-10-25 塞拉尼斯伊娃高性能聚合物公司 用于持续释放大分子药物化合物的可植入器件
US20240115490A1 (en) * 2018-12-11 2024-04-11 Lupin Inc. Drug delivery system for ultra-low dose estrogen combinations and methods and uses thereof
WO2020123148A1 (en) * 2018-12-11 2020-06-18 Lupin Inc. Drug delivery system for ultra-low dose estrogen combinations and methods and uses thereof
US20230404911A1 (en) * 2018-12-11 2023-12-21 Lupin Inc. Drug delivery system for ultra-low dose estrogen combinations and methods and uses thereof
CN112315898B (zh) * 2020-11-04 2021-08-13 国家卫生健康委科学技术研究所 含有芳香化酶抑制剂的阴道缓控释给药系统及其制备方法
EP4329734A4 (en) 2021-04-26 2025-04-02 Celanese EVA Performance Polymers LLC Implantable device for the delayed release of a macromolecular drug compound

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3920805A (en) 1971-12-09 1975-11-18 Upjohn Co Pharmaceutical devices and method
US4215691A (en) 1978-10-11 1980-08-05 Alza Corporation Vaginal contraceptive system made from block copolymer
US4292965A (en) 1978-12-29 1981-10-06 The Population Council, Inc. Intravaginal ring
DE3040978A1 (de) 1980-10-28 1982-05-27 Schering Ag, 1000 Berlin Und 4619 Bergkamen Vaginalring
FR2618329B1 (fr) 1987-07-22 1997-03-28 Dow Corning Sa Procede de fabrication d'un anneau capable d'assurer la liberation d'un agent therapeutique, et anneau fabrique par ce procede
FI90627C (fi) 1992-07-31 1994-03-10 Leiras Oy Laitteisto lääkeainesauvan varustamiseksi vaipalla
PH30867A (en) 1992-07-31 1997-12-09 Leiras Oy Method and equipment for installing a medicine capsule on a support.
DK0836473T3 (da) 1995-07-04 2002-02-11 Akzo Nobel Nv Ringformede indretninger
IL123813A0 (en) 1997-04-11 1998-10-30 Akzo Nobel Nv Drug delivery system for two or more active substances
FI107339B (fi) 1998-06-30 2001-07-13 Leiras Oy Lääkeaineiden läpäisynopeutta säätävä kalvo tai matriisi
US6056976A (en) 1998-11-12 2000-05-02 Leiras Oy Elastomer, its preparation and use
US6063395A (en) * 1998-11-12 2000-05-16 Leiras Oy Drug delivery device especially for the delivery of progestins and estrogens
US6476079B1 (en) * 1999-12-23 2002-11-05 Leiras Oy Devices for the delivery of drugs having antiprogestinic properties
CN1289064C (zh) 2001-08-31 2006-12-13 先灵有限责任公司 药物输送体系
JP4898431B2 (ja) * 2003-04-29 2012-03-14 ザ ジェネラル ホスピタル コーポレイション 複数薬物の持続放出のための方法およびデバイス
TW200927141A (en) * 2007-11-22 2009-07-01 Bayer Schering Pharma Oy Vaginal delivery system
EP2062568A1 (en) 2007-11-22 2009-05-27 Bayer Schering Pharma Oy Vaginal delivery system
EP2140860A1 (en) 2008-07-03 2010-01-06 Bayer Schering Pharma Oy An improved method of contraception
FI121000B (fi) 2008-11-19 2010-06-15 Bayer Schering Pharma Oy Intravaginaalinen antojärjestelmä ja menetelmä sen valmistamiseksi
US20140209100A1 (en) * 2011-07-20 2014-07-31 Patrick F. Kiser Intravaginal devices for drug delivery
HUE049219T2 (hu) * 2013-02-08 2020-09-28 Qpharma Ab Intravaginális eszköz, valamint eljárás az intravaginális eszközben lévõ hatóanyag diffúziós sebességének csökkentésére

Also Published As

Publication number Publication date
EP3294300A1 (en) 2018-03-21
US20260053736A1 (en) 2026-02-26
CN108135910B (zh) 2022-12-02
US12357563B2 (en) 2025-07-15
CN108135910A (zh) 2018-06-08
ES3009909T3 (en) 2025-03-31
US20210338573A1 (en) 2021-11-04
US20180104181A1 (en) 2018-04-19
WO2016180764A1 (en) 2016-11-17
CA2985717A1 (en) 2016-11-17
EP3294300B1 (en) 2024-12-18
JP2018516889A (ja) 2018-06-28
US11096888B2 (en) 2021-08-24
FI3294300T3 (fi) 2025-03-06

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