PE20211195A1 - Un metodo para modificar la liberacion de un agente terapeuticamente activo de una matriz elastomerica - Google Patents
Un metodo para modificar la liberacion de un agente terapeuticamente activo de una matriz elastomericaInfo
- Publication number
- PE20211195A1 PE20211195A1 PE2020000735A PE2020000735A PE20211195A1 PE 20211195 A1 PE20211195 A1 PE 20211195A1 PE 2020000735 A PE2020000735 A PE 2020000735A PE 2020000735 A PE2020000735 A PE 2020000735A PE 20211195 A1 PE20211195 A1 PE 20211195A1
- Authority
- PE
- Peru
- Prior art keywords
- core
- pyycomethycene
- therapeutically active
- active agent
- elastomeric matrix
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
- A61K9/0036—Devices retained in the vagina or cervix for a prolonged period, e.g. intravaginal rings, medicated tampons, medicated diaphragms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/196—Carboxylic acids, e.g. valproic acid having an amino group the amino group being directly attached to a ring, e.g. anthranilic acid, mefenamic acid, diclofenac, chlorambucil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
- A61K31/404—Indoles, e.g. pindolol
- A61K31/405—Indole-alkanecarboxylic acids; Derivatives thereof, e.g. tryptophan, indomethacin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
- A61K31/5415—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with carbocyclic ring systems, e.g. phenothiazine, chlorpromazine, piroxicam
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
- A61K9/0039—Devices retained in the uterus for a prolonged period, e.g. intrauterine devices for contraception
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/485—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5026—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Reproductive Health (AREA)
- Inorganic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Gynecology & Obstetrics (AREA)
- Urology & Nephrology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
SE REFIERE A UN METODO PARA MODIFICAR LA LIBERACION DE UN AGENTE TERAPEUTICAMENTE ACTIVO DE UNA MATRIZ ELASTOMERICA, EL CUAL COMPRENDE: A) PROPORCIONAR UN NUCLEO QUE COMPRENDE UNA MATRIZ ELASTOMERICA Y UN AGENTE TERAPEUTICAMENTE ACTIVO TAL COMO INDOMETACINA, DICLOFENACO, PIROXICAM, MELOXICAM Y CETOPROFENO; B) SUMERGIR EL NUCLEO EN UNA SOLUCION DE RECUBRIMIENTO QUE COMPRENDE UN ELASTOMERO QUE CONTIENE 20-35% EN PESO DE UN AGENTE DE RELLENO TAL COMO SILICE, DIOXIDO DE TITANIO, SULFATO DE BARIO, CARBONO Y LAS MEZCLAS DE LOS MISMOS, CALCULADO DE LA CANTIDAD TOTAL DE AGENTE DE RELLENO Y ELASTOMERO; C) CURAR EL NUCLEO SUMERGIDO PARA PROPORCIONAR UN NUCLEO RECUBIERTO; DONDE EL ELASTOMERO COMPRENDIDO EN EL NUCLEO Y EL ELASTOMERO COMPRENDIDO EN LA SOLUCION DE RECUBRIMIENTO SE SELECCIONAN DE POLI(DIMETIL)SILOXANOS, POLIETILENO ACETATOS DE VINILO (EVA), POLIURETANOS (PU), POLIHIDROXIETIL-METACRILATOS (PHEMA) Y POLIMETIL-METACRILATOS (PMMA).
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP17193367 | 2017-09-27 | ||
EP18167014 | 2018-04-12 | ||
PCT/EP2018/075331 WO2019063382A1 (en) | 2017-09-27 | 2018-09-19 | METHOD FOR MODIFYING THE RELEASE OF A THERAPEUTICALLY ACTIVE AGENT FROM AN ELASTOMERIC MATRIX |
Publications (1)
Publication Number | Publication Date |
---|---|
PE20211195A1 true PE20211195A1 (es) | 2021-07-01 |
Family
ID=63592747
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PE2020000735A PE20211195A1 (es) | 2017-09-27 | 2018-09-19 | Un metodo para modificar la liberacion de un agente terapeuticamente activo de una matriz elastomerica |
Country Status (18)
Country | Link |
---|---|
US (1) | US11666552B2 (es) |
EP (1) | EP3687495A1 (es) |
JP (1) | JP7242648B2 (es) |
KR (1) | KR20200059224A (es) |
CN (1) | CN111148507B (es) |
AU (1) | AU2018340266A1 (es) |
BR (1) | BR112020005928A2 (es) |
CA (1) | CA3076768A1 (es) |
CL (1) | CL2020000778A1 (es) |
CO (1) | CO2020003454A2 (es) |
IL (1) | IL272878A (es) |
JO (1) | JOP20200067A1 (es) |
MX (1) | MX2020007323A (es) |
PE (1) | PE20211195A1 (es) |
SG (1) | SG11202001293SA (es) |
TW (1) | TW201919587A (es) |
UY (1) | UY37906A (es) |
WO (1) | WO2019063382A1 (es) |
Family Cites Families (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1222897A (zh) * | 1996-03-29 | 1999-07-14 | 盖里列奥公司 | 用于形成光学纤维的可剥离聚酰亚胺涂层之方法 |
US6117442A (en) * | 1998-11-12 | 2000-09-12 | Leiras Oy | Drug delivery device, especially for the delivery of androgens |
US6063395A (en) * | 1998-11-12 | 2000-05-16 | Leiras Oy | Drug delivery device especially for the delivery of progestins and estrogens |
AU2002210580A1 (en) | 2000-10-20 | 2002-04-29 | Leiras Oy | Drug delivery system |
US20020136573A1 (en) * | 2001-01-25 | 2002-09-26 | Xerox Corporation | Infrared curing of fluoroelastomer coatings formed over silicone rubber in a fuser member |
WO2005004837A1 (en) * | 2003-07-10 | 2005-01-20 | Galen (Chemicals) Limited | Intravaginal drug delivery devices |
US7914841B2 (en) * | 2006-02-09 | 2011-03-29 | Cook Medical Technologies Llc | Inline application of coatings |
TW200927141A (en) * | 2007-11-22 | 2009-07-01 | Bayer Schering Pharma Oy | Vaginal delivery system |
EP2140860A1 (en) | 2008-07-03 | 2010-01-06 | Bayer Schering Pharma Oy | An improved method of contraception |
WO2011156648A1 (en) * | 2010-06-09 | 2011-12-15 | President And Fellows Of Harvard College | Method for producing films |
US9801831B2 (en) * | 2010-12-30 | 2017-10-31 | Nanyang Technological University | Device for controlled release of a bioactive agent |
KR20120135689A (ko) * | 2011-06-07 | 2012-12-17 | (주) 태웅메디칼 | 약물 방출 스텐트 코팅제의 제조방법 및 이에 의해 제조된 약물 방출 스텐트 코팅제 |
US20130236524A1 (en) | 2011-09-09 | 2013-09-12 | Axxia Pharmaceuticals, Llc | Silicone coated implant |
US9434857B2 (en) * | 2011-11-15 | 2016-09-06 | Ethicon, Inc. | Rapid cure silicone lubricious coatings |
AR089765A1 (es) | 2012-01-23 | 2014-09-17 | Bayer Oy | Un sistema para el suministro de un farmaco |
US20140037964A1 (en) * | 2012-08-02 | 2014-02-06 | Haipeng Zheng | Optical Article Containing A Self-Healing Coating And Improved Initial Haze |
PE20160534A1 (es) | 2013-10-18 | 2016-06-15 | Bayer Oy | Sistema de administracion intrauterina |
LT3247327T (lt) * | 2015-01-21 | 2019-10-10 | Bayer Oy | Vaisto pateikimo sistema, apimanti nesteroidinį priešuždegiminį (nsaid) ir progestogeninį junginį, ir gamybos būdai |
BR112018012743A2 (pt) | 2015-12-21 | 2018-12-04 | Bayer Oy | método para fabricar um dispositivo de administração de medicamento e um dispositivo de administração de medicamento fabricado de acordo com o método |
EP3551280B1 (en) * | 2016-12-12 | 2023-08-09 | The Regents of the University of California | Implantable and non-invasive stimulators for gastrointestinal therapeutics |
-
2018
- 2018-09-19 EP EP18770027.3A patent/EP3687495A1/en active Pending
- 2018-09-19 WO PCT/EP2018/075331 patent/WO2019063382A1/en unknown
- 2018-09-19 CA CA3076768A patent/CA3076768A1/en active Pending
- 2018-09-19 JP JP2020517371A patent/JP7242648B2/ja active Active
- 2018-09-19 US US16/649,944 patent/US11666552B2/en active Active
- 2018-09-19 BR BR112020005928-5A patent/BR112020005928A2/pt unknown
- 2018-09-19 AU AU2018340266A patent/AU2018340266A1/en not_active Abandoned
- 2018-09-19 CN CN201880062728.3A patent/CN111148507B/zh active Active
- 2018-09-19 KR KR1020207008324A patent/KR20200059224A/ko not_active Application Discontinuation
- 2018-09-19 PE PE2020000735A patent/PE20211195A1/es unknown
- 2018-09-19 JO JOP/2020/0067A patent/JOP20200067A1/ar unknown
- 2018-09-19 MX MX2020007323A patent/MX2020007323A/es unknown
- 2018-09-19 SG SG11202001293SA patent/SG11202001293SA/en unknown
- 2018-09-26 TW TW107133758A patent/TW201919587A/zh unknown
- 2018-09-27 UY UY0001037906A patent/UY37906A/es not_active Application Discontinuation
-
2020
- 2020-02-24 IL IL272878A patent/IL272878A/en unknown
- 2020-03-25 CO CONC2020/0003454A patent/CO2020003454A2/es unknown
- 2020-03-25 CL CL2020000778A patent/CL2020000778A1/es unknown
Also Published As
Publication number | Publication date |
---|---|
CN111148507A (zh) | 2020-05-12 |
IL272878A (en) | 2020-04-30 |
KR20200059224A (ko) | 2020-05-28 |
JP7242648B2 (ja) | 2023-03-20 |
CL2020000778A1 (es) | 2020-09-25 |
JOP20200067A1 (ar) | 2020-04-27 |
EP3687495A1 (en) | 2020-08-05 |
TW201919587A (zh) | 2019-06-01 |
CO2020003454A2 (es) | 2020-04-13 |
US11666552B2 (en) | 2023-06-06 |
CN111148507B (zh) | 2023-09-26 |
SG11202001293SA (en) | 2020-03-30 |
CA3076768A1 (en) | 2019-04-04 |
RU2020113426A3 (es) | 2022-02-22 |
US20200276159A1 (en) | 2020-09-03 |
RU2020113426A (ru) | 2021-10-27 |
BR112020005928A2 (pt) | 2020-10-06 |
AU2018340266A1 (en) | 2020-03-05 |
WO2019063382A1 (en) | 2019-04-04 |
JP2020535159A (ja) | 2020-12-03 |
MX2020007323A (es) | 2020-09-07 |
UY37906A (es) | 2019-02-28 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
MX2016012151A (es) | Composiciones termicamente expandibles. | |
MX2017011184A (es) | Proceso para producir un cuerpo curado fotocromico. | |
AR097032A1 (es) | Hidrogeles de poli(alquenilamida)-polisacárido para el tratamiento de formaciones subterráneas | |
AR095446A1 (es) | Métodos para entrecruzar composiciones de polímeros en la presencia de oxígeno atmosférico | |
UY38160A (es) | Partículas implantables y métodos relacionados | |
BR112017012663A2 (pt) | composição de cuidados com o sol, películas de enrijecimento da pele e de cuidados com o sol, e, método para proteger a pele de raios uv. | |
EP3243884A4 (en) | Radiation curable coating composition, low-refractive-index layer, and antireflective film | |
CR20180228A (es) | Terapia adjunta con 25-hidroxi vitamina d y articulos de la misma | |
AR085096A1 (es) | Control de aleurodios | |
BR112015022625A2 (pt) | micromatrizes para entrega de agente terapêutico e métodos de uso | |
NI201000156A (es) | Compuestos heterocíclicos novedosos y usos de los mismos. | |
WO2013103533A3 (en) | Free radical polymerizable compositions comprising ionic silicones | |
PE20121790A1 (es) | Composiciones de liberacion controlada | |
CL2017002031A1 (es) | Formulación en polvo nasal para el tratamiento de hipoglicemia | |
BR112018009311A8 (pt) | ?método para tratar um sujeito humano sofrendo de tma persistente associada com transplante de célula tronco hematopoiética? | |
MX2018003725A (es) | Composiciones termicamente expandibles que comprenden polisacarido. | |
CR20150543A (es) | Método de tratamiento de páncreas e hígado para condiciones por transplante de células madre en paredes de conducto biliar | |
AR105350A1 (es) | Composición de limpieza con propelente | |
BR112017023722A2 (pt) | composição formadora de película curável, substrato revestido e método para revestir um substrato | |
CL2018003826A1 (es) | Uso de una fracción lignina como un agente anti fitopatogenico y composiciones fitopatogenicas conteniendo dicho agente. | |
UY35803A (es) | Recubrimiento de alginato para tratamiento de esquejes | |
AR095905A1 (es) | Proceso para el entrecruzamiento de elastómeros | |
BR112013007656A2 (pt) | Composição iniciadora de silicone, seus usos e seu método de produção | |
BR112019023919A2 (pt) | cateter de liberação de stent com controle de cursor rápido e roda de acionamento lenta | |
CL2017000977A1 (es) | Método de tratamiento para antibrote de tubérculos con cantidad reducida de cipc |