JP6895968B2 - サイトカインおよびカルボキシルエステラーゼを発現する腫瘍溶解性改変ワクシニアウイルス、および、その使用方法 - Google Patents

サイトカインおよびカルボキシルエステラーゼを発現する腫瘍溶解性改変ワクシニアウイルス、および、その使用方法 Download PDF

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JP6895968B2
JP6895968B2 JP2018531280A JP2018531280A JP6895968B2 JP 6895968 B2 JP6895968 B2 JP 6895968B2 JP 2018531280 A JP2018531280 A JP 2018531280A JP 2018531280 A JP2018531280 A JP 2018531280A JP 6895968 B2 JP6895968 B2 JP 6895968B2
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vaccinia virus
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JP2018526450A5 (enExample
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ホ ファン，テ
ホ ファン，テ
ヒ イ，ナム
ヒ イ，ナム
チョ，ウンア
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シルラジェン インコーポレイテッド
シルラジェン インコーポレイテッド
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JP2018531280A 2015-09-08 2016-09-02 サイトカインおよびカルボキシルエステラーゼを発現する腫瘍溶解性改変ワクシニアウイルス、および、その使用方法 Active JP6895968B2 (ja)

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US201562215651P 2015-09-08 2015-09-08
US62/215,651 2015-09-08
PCT/KR2016/009866 WO2017043815A1 (en) 2015-09-08 2016-09-02 Modified oncolytic vaccinia viruses expressing a cytokine and a car- boxylesterase and methods of use thereof

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JP2018526450A JP2018526450A (ja) 2018-09-13
JP2018526450A5 JP2018526450A5 (enExample) 2019-08-29
JP6895968B2 true JP6895968B2 (ja) 2021-06-30

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US (1) US10646524B2 (enExample)
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CN (1) CN108350434B (enExample)
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JP7551496B2 (ja) 2017-10-31 2024-09-17 カリヴィル イムノセラピューティクス， インコーポレイテッド 全身送達のためのプラットフォーム腫瘍溶解性ベクター
WO2019148109A1 (en) * 2018-01-26 2019-08-01 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Expression of metabolic modulators in tumor microenvironment to improve tumor therapy
CN118147029A (zh) 2018-07-11 2024-06-07 阿克蒂姆治疗有限公司 工程化的免疫刺激性细菌菌株及其用途
CN116162654A (zh) * 2018-09-15 2023-05-26 纪念斯隆凯特琳癌症中心 用于癌症免疫疗法的重组痘病毒
CN109735558B (zh) * 2018-12-12 2022-04-15 中南大学 一种重组car19-il24基因、慢病毒载体、car19-il24-t细胞及应用
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WO2021116943A1 (en) * 2019-12-12 2021-06-17 Ignite Immunotherapy, Inc. Variant oncolytic vaccinia virus and methods of use thereof
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US20240102912A1 (en) * 2020-11-09 2024-03-28 Thrive Bioscience, Inc. Plaque counting assay method
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JP2024542173A (ja) 2021-11-09 2024-11-13 アクティム・セラピューティクス・インコーポレイテッド マクロファージを処置に適している表現型に変換するための免疫刺激細菌および処置のための対象の同定のためのコンパニオン診断法

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SMT202400047T1 (it) * 2013-08-22 2024-03-13 Univ Pittsburgh Commonwealth Sys Higher Education Terapie immuno-oncolitiche

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US10646524B2 (en) 2020-05-12
US20180271921A1 (en) 2018-09-27
CN108350434B (zh) 2022-06-07
KR102674362B1 (ko) 2024-06-13
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