JP6883529B2 - 融合タンパク質を合成するための方法および製品 - Google Patents
融合タンパク質を合成するための方法および製品 Download PDFInfo
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- JP6883529B2 JP6883529B2 JP2017563189A JP2017563189A JP6883529B2 JP 6883529 B2 JP6883529 B2 JP 6883529B2 JP 2017563189 A JP2017563189 A JP 2017563189A JP 2017563189 A JP2017563189 A JP 2017563189A JP 6883529 B2 JP6883529 B2 JP 6883529B2
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Classifications
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- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/315—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci
- C07K14/3156—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci from Streptococcus pneumoniae (Pneumococcus)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/315—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/04—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
-
- C—CHEMISTRY; METALLURGY
- C40—COMBINATORIAL TECHNOLOGY
- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
- C40B40/00—Libraries per se, e.g. arrays, mixtures
- C40B40/04—Libraries containing only organic compounds
- C40B40/10—Libraries containing peptides or polypeptides, or derivatives thereof
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/90—Fusion polypeptide containing a motif for post-translational modification
Landscapes
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- Organic Chemistry (AREA)
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| GB1509782.7 | 2015-06-06 | ||
| PCT/GB2016/051640 WO2016193746A1 (fr) | 2015-06-05 | 2016-06-03 | Procédés et produits pour la synthèse de protéines de fusion |
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| AU2016207099C1 (en) | 2015-01-15 | 2021-02-04 | University Of Copenhagen | Virus-like particle with efficient epitope display |
| ES2854726T3 (es) | 2015-10-30 | 2021-09-22 | The Univ Of Copenhagen | Partícula similar a virus con presentación eficiente de epítopos |
| WO2018170362A2 (fr) * | 2017-03-16 | 2018-09-20 | The Penn State Research Foundation | Échafaudages de présentation polyvalents pour protéines |
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| GB201706430D0 (en) | 2017-04-24 | 2017-06-07 | Univ Oxford Innovation Ltd | Proteins and peptide tags with enhanced rate of spontaneous isopeptide bond formation and uses thereof |
| CN107299107A (zh) * | 2017-07-31 | 2017-10-27 | 北京大学 | 一种蛋白质层层组装功能材料的制备方法 |
| EP3701009A1 (fr) | 2017-10-25 | 2020-09-02 | Abera Bioscience AB | Exposition de molécules hétérologues sur des cellules bactériennes et des vésicules membranaires |
| EP3774926A1 (fr) | 2018-04-05 | 2021-02-17 | Bio-Rad ABD Serotec GmbH | Systèmes d'affichage pour protéines d'intérêt |
| BR112020022393A2 (pt) | 2018-05-04 | 2021-02-02 | SpyBiotech Limited | composição, vacina compreendendo uma composição, método para produzir uma composição, molécula de ácido nucleico, e, vetor, célula hospedeira, kit compreendendo uma composição, e, vacinas para uso na profilaxia e/ou tratamento de infecção por citomegalovírus e por vírus sincicial respiratório. |
| US20210310910A1 (en) * | 2018-08-20 | 2021-10-07 | The Regents Of The University Of California | Graphene Oxide Affinity Sample Grids for Cyro-EM |
| CN111073925B (zh) * | 2018-10-19 | 2022-04-26 | 北京大学 | 一种基于无序蛋白偶联酶的高效多肽-多肽偶联系统和方法 |
| GB201819850D0 (en) | 2018-12-05 | 2019-01-23 | Univ Oxford Innovation Ltd | Polypeptide and its use in affinity purification |
| GB201903479D0 (en) * | 2019-03-14 | 2019-05-01 | Univ Oxford Innovation Ltd | Polypeptide with enchanced rate of spontaneous isopeptide bond formation with it's peptide tag partner and uses thereof |
| AU2020243436A1 (en) * | 2019-03-18 | 2021-10-07 | Bio-Rad Abd Serotec Gmbh | Antigen binding fragments conjugated to a plurality of Fc isotypes and subclasses |
| EP3942079A1 (fr) | 2019-03-18 | 2022-01-26 | Bio-Rad ABD Serotec GmbH | Protection de protéines de fusion périplasmiques contenant des marqueurs spytag à partir d'une dégradation de protéase tsp et ompt |
| CN113811548A (zh) * | 2019-03-18 | 2021-12-17 | 生物辐射Abd瑟罗泰克有限公司 | 抗原结合蛋白 |
| NL2023863B1 (en) | 2019-09-20 | 2021-05-25 | Univ Griffith | Protein particles and uses thereof |
| GB201915905D0 (en) | 2019-11-01 | 2019-12-18 | Spybiotech Ltd | Viruses with modified capsid proteins |
| EP3831843A1 (fr) | 2019-12-08 | 2021-06-09 | Royal College Of Surgeons In Ireland | Agent hémostatique et ses utilisations |
| US20240294585A1 (en) * | 2020-04-13 | 2024-09-05 | Colin David Gottlieb | Modular binding proteins for extracellular vesicles and uses thereof |
| CN115698045A (zh) * | 2020-05-07 | 2023-02-03 | 阿戴普瓦克有限公司 | 肽标签和结合配偶体 |
| WO2022076914A1 (fr) | 2020-10-09 | 2022-04-14 | 10X Genomics, Inc. | Procédés et compositions pour le profilage d'un répertoire immunitaire |
| GB202019817D0 (en) | 2020-12-15 | 2021-01-27 | Univ Oxford Innovation Ltd | Ligand-binding polypeptides and uses thereof |
| GB202104104D0 (en) * | 2021-03-24 | 2021-05-05 | Liliumx Ltd | Platform and method |
| GB202104999D0 (en) | 2021-04-08 | 2021-05-26 | Univ Oxford Innovation Ltd | Polypeptides that interact with peptide tags at loops or termini and uses thereof |
| CN113621031B (zh) * | 2021-04-23 | 2023-05-05 | 中山大学 | 一种利用自发异肽键进行蛋白共价自组装的肽链接头的组合 |
| US20240240203A1 (en) | 2021-05-04 | 2024-07-18 | SpyBiotech Limited | Adenoviral vectors and vaccines thereof |
| GB202106361D0 (en) | 2021-05-04 | 2021-06-16 | Spybiotech Ltd | Viral vectored vaccines |
| WO2023049774A1 (fr) * | 2021-09-21 | 2023-03-30 | University Of Washington | Ligature de protéine-protéine à déclenchement exogène et génétiquement codée |
| CN113862235B (zh) * | 2021-09-24 | 2024-07-05 | 苏州近岸蛋白质科技股份有限公司 | 一种嵌合酶及其在体外一步反应合成Cap0 mRNA的用途和方法 |
| GB202117283D0 (en) | 2021-11-30 | 2022-01-12 | Univ Oxford Innovation Ltd | Switchable polypeptide and its use for gentle affinity purification |
| WO2023102156A1 (fr) | 2021-12-03 | 2023-06-08 | Wisconsin Alumni Research Foundation | Protéines ace2 mutantes et leurs procédés d'utilisation |
| EP4206674A1 (fr) | 2021-12-28 | 2023-07-05 | Encodia, Inc. | Dosages de sérotypage et de profilage d'anticorps à haut débit |
| CN114672505A (zh) * | 2022-03-15 | 2022-06-28 | 江苏省中国科学院植物研究所 | 一种功能性表达细胞色素p450酶的方法及其应用 |
| CN114732898B (zh) * | 2022-04-01 | 2023-05-09 | 中国人民解放军军事科学院军事医学研究院 | 一种CpG佐剂与抗原定点共价结合方法 |
| WO2024006532A2 (fr) * | 2022-06-30 | 2024-01-04 | La Jolla Institute For Immunology | Nanoparticule de kari |
| WO2024064112A2 (fr) * | 2022-09-19 | 2024-03-28 | The Rockefeller University | Capture d'affinité et détermination directe de structures de protéines et d'autres matieres sur des billes superparamagnétiques par une analyse de microscopie cryo-électronique à particule unique |
| WO2024069180A2 (fr) | 2022-09-28 | 2024-04-04 | LiliumX Ltd. | Protéines multivalentes et procédés de criblage |
| CN116165377A (zh) * | 2023-04-21 | 2023-05-26 | 常州伯仪生物科技有限公司 | 一种通过竞争elisa法进行标签蛋白定量的方法 |
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| AU530410B2 (en) | 1978-02-21 | 1983-07-14 | Sintef | Preparing aqueous emulsions |
| JP2002531055A (ja) * | 1998-07-27 | 2002-09-24 | マイクロビアル テクニクス リミティッド | 肺炎連鎖球菌のタンパク質及び核酸分子 |
| US6936252B2 (en) * | 1998-07-27 | 2005-08-30 | Microbial Technics Limited | Streptococcus pneumoniae proteins and nucleic acid molecules |
| DE10108263A1 (de) * | 2001-02-21 | 2002-09-05 | Max Planck Gesellschaft | Analyse von Modifizierungen und Demodifizierungen von Proteinen mit Ubiquitinverwandten Proteinen mittels FRET (Fluorescence Resonance Energy Transfer) |
| WO2004031243A1 (fr) * | 2002-10-01 | 2004-04-15 | Kumamoto Technology & Industry Foundation | Polymere de proteine et procede de production correspondant |
| CA2651793C (fr) * | 2006-02-02 | 2015-07-07 | Trimeris, Inc. | Peptides inhibiteurs de fusion du vih a proprietes biologiques ameliorees |
| CA2688284A1 (fr) * | 2007-05-25 | 2008-12-04 | Novartis Ag | Antigenes de pilus de streptococcus pneumoniae |
| GB0714963D0 (en) * | 2007-08-01 | 2007-09-12 | Novartis Ag | Compositions comprising antigens |
| EP2215227A2 (fr) * | 2007-11-05 | 2010-08-11 | Promega Corporation | Reporteur de fusion hybride et ses utilisations |
| GB201002362D0 (en) * | 2010-02-11 | 2010-03-31 | Isis Innovation | Peptide tag systems that spontaneously form an irreversible link to protein partners via isopeptide bonds |
| FR2973032A1 (fr) | 2011-03-24 | 2012-09-28 | Commissariat Energie Atomique | Peptides aptes a former un complexe covalent et leurs utilisations |
| US20120259101A1 (en) | 2011-04-11 | 2012-10-11 | Li Tan | Isopeptide Bond Formation in Bacillus Species and Uses Thereof |
| EP3008094B1 (fr) | 2013-06-14 | 2018-12-26 | Pacific Biosciences Of California, Inc. | Étiquettes de bis-biotinylation |
| US10073087B2 (en) | 2014-01-15 | 2018-09-11 | Massachusetts Institute Of Technology | Biopolymer-mediated assembly of nanoparticles using genetically encoded proteins |
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Also Published As
| Publication number | Publication date |
|---|---|
| JP2018521640A (ja) | 2018-08-09 |
| CN108026148A (zh) | 2018-05-11 |
| EP3303374A1 (fr) | 2018-04-11 |
| WO2016193746A1 (fr) | 2016-12-08 |
| CN116199733A (zh) | 2023-06-02 |
| CN108026148B (zh) | 2022-12-30 |
| AU2016272543A1 (en) | 2018-01-04 |
| CA2987821A1 (fr) | 2016-12-08 |
| US20180244730A1 (en) | 2018-08-30 |
| BR112017026042A2 (pt) | 2018-08-14 |
| ES2880336T3 (es) | 2021-11-24 |
| DK3303374T3 (da) | 2021-07-05 |
| AU2016272543B2 (en) | 2020-08-13 |
| KR20180050640A (ko) | 2018-05-15 |
| EP3303374B1 (fr) | 2021-03-31 |
| GB201509782D0 (en) | 2015-07-22 |
| US10526379B2 (en) | 2020-01-07 |
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