JP6865736B2 - 腫瘍溶解性ｈｓｖ１ベクターおよび使用法 - Google Patents

腫瘍溶解性ｈｓｖ１ベクターおよび使用法 Download PDF

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JP6865736B2
JP6865736B2 JP2018510313A JP2018510313A JP6865736B2 JP 6865736 B2 JP6865736 B2 JP 6865736B2 JP 2018510313 A JP2018510313 A JP 2018510313A JP 2018510313 A JP2018510313 A JP 2018510313A JP 6865736 B2 JP6865736 B2 JP 6865736B2
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cells
tumor
vector
pharmaceutical composition
nestin
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JP2018518986A (ja
JP2018518986A5 (enExample
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ヒロシ ナカシマ
ヒロシ ナカシマ
エンニオ アントニオ チョッカ
エンニオ アントニオ チョッカ
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The Brigham and Women's Hospital Inc
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    • A—HUMAN NECESSITIES
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JP2018510313A 2015-05-04 2016-05-04 腫瘍溶解性ｈｓｖ１ベクターおよび使用法 Active JP6865736B2 (ja)

Applications Claiming Priority (3)

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US201562156447P 2015-05-04 2015-05-04
US62/156,447 2015-05-04
PCT/US2016/030681 WO2016179226A1 (en) 2015-05-04 2016-05-04 Oncolytic hsv1 vector and methods of use

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JP2018518986A JP2018518986A (ja) 2018-07-19
JP2018518986A5 JP2018518986A5 (enExample) 2019-02-21
JP6865736B2 true JP6865736B2 (ja) 2021-04-28

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US (1) US10806761B2 (enExample)
EP (2) EP3981438A1 (enExample)
JP (1) JP6865736B2 (enExample)
KR (1) KR102705177B1 (enExample)
CN (1) CN108025088B (enExample)
AU (2) AU2016257910B2 (enExample)
CA (1) CA2988196C (enExample)
DK (1) DK3291841T3 (enExample)
ES (1) ES2903349T3 (enExample)
WO (1) WO2016179226A1 (enExample)

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CN110582574A (zh) * 2017-03-13 2019-12-17 麻省理工学院 合成启动子
KR101974169B1 (ko) 2018-08-10 2019-04-30 의료법인 성광의료재단 재조합 단순 헤르페스 바이러스 및 이의 제조방법
SG11202105422RA (en) * 2018-11-29 2021-06-29 Virogin Biotech Canada Ltd Hsv vector with reduced neurotoxicity
CA3132867A1 (en) * 2019-03-14 2020-09-17 Research Institute At Nationwide Children's Hospital Syncytial oncolytic herpes simplex mutants as potent cancer therapeutics
KR102333650B1 (ko) * 2019-11-08 2021-12-01 한국해양과학기술원 신규한 인간 상피세포성장인자 융합 단백질 및 이의 용도
US20240024392A1 (en) * 2020-12-04 2024-01-25 Immvira Co., Limited Oncolytic herpes simplex type 1 viruses for treatment of brain tumors
WO2026076297A1 (en) * 2024-10-03 2026-04-09 Candel Therapeutics, Inc. Compositions and methods for treating melanoma using an oncolytic virus

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US4683202A (en) 1985-03-28 1987-07-28 Cetus Corporation Process for amplifying nucleic acid sequences
US5728379A (en) 1994-06-23 1998-03-17 Georgetown University Tumor- or cell-specific herpes simplex virus replication
US5928906A (en) 1996-05-09 1999-07-27 Sequenom, Inc. Process for direct sequencing during template amplification
US6897057B1 (en) 1999-08-31 2005-05-24 The General Hospital Corporation Cell-specific and/or tumor-specific promoter retargeting of herpes γ 34.5 gene expression
WO2002053576A1 (en) 2001-01-05 2002-07-11 The General Hospital Corporation Viral delivery system for infectious transfer of large genomic dna inserts
WO2005080581A2 (en) * 2004-02-17 2005-09-01 University Of Florida Research Foundation, Inc. Insulated herpesvirus-derived gene expression cassettes for sustained and regulatable gene expression
WO2005103237A1 (ja) * 2004-03-31 2005-11-03 Tomoki Todo 組換え単純ヘルペスウイルスの作製方法
EP2123051B1 (en) * 2006-12-18 2010-11-10 Koninklijke Philips Electronics N.V. Image compression and decompression
US8450106B2 (en) * 2007-10-17 2013-05-28 The Ohio State University Research Foundation Oncolytic virus
WO2009148488A2 (en) * 2008-05-29 2009-12-10 The General Hospital Corporation Use of oncolytic herpes viruses for killing cancer stem cells
EP2920312B1 (en) 2012-11-14 2020-01-08 The Brigham and Women's Hospital, Inc. Oncolytic hsv1 vectors and methods of using the same

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AU2016257910B2 (en) 2021-06-24
CA2988196C (en) 2021-04-27
CA2988196A1 (en) 2016-11-10
EP3291841B1 (en) 2021-10-20
US20180133269A1 (en) 2018-05-17
AU2021232778B2 (en) 2024-12-19
CN108025088B (zh) 2021-08-10
AU2016257910A1 (en) 2017-12-21
AU2021232778A1 (en) 2021-10-14
EP3291841A1 (en) 2018-03-14
ES2903349T3 (es) 2022-04-01
KR102705177B1 (ko) 2024-09-11
KR20180037140A (ko) 2018-04-11
WO2016179226A1 (en) 2016-11-10
DK3291841T3 (da) 2022-01-10
JP2018518986A (ja) 2018-07-19
CN108025088A (zh) 2018-05-11
EP3981438A1 (en) 2022-04-13
US10806761B2 (en) 2020-10-20
EP3291841A4 (en) 2018-12-05

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