JP6865736B2 - 腫瘍溶解性ｈｓｖ１ベクターおよび使用法 - Google Patents

腫瘍溶解性ｈｓｖ１ベクターおよび使用法 Download PDF

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JP6865736B2
JP6865736B2 JP2018510313A JP2018510313A JP6865736B2 JP 6865736 B2 JP6865736 B2 JP 6865736B2 JP 2018510313 A JP2018510313 A JP 2018510313A JP 2018510313 A JP2018510313 A JP 2018510313A JP 6865736 B2 JP6865736 B2 JP 6865736B2
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cells
tumor
vector
pharmaceutical composition
nestin
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JP2018518986A5 (enExample
JP2018518986A (ja
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ヒロシ ナカシマ
ヒロシ ナカシマ
エンニオ アントニオ チョッカ
エンニオ アントニオ チョッカ
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Brigham and Womens Hospital Inc
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    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • C12N2710/16611—Simplexvirus, e.g. human herpesvirus 1, 2
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    • C12N2710/16011—Herpesviridae
    • C12N2710/16611—Simplexvirus, e.g. human herpesvirus 1, 2
    • C12N2710/16641—Use of virus, viral particle or viral elements as a vector
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JP2018510313A 2015-05-04 2016-05-04 腫瘍溶解性ｈｓｖ１ベクターおよび使用法 Active JP6865736B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562156447P 2015-05-04 2015-05-04
US62/156,447 2015-05-04
PCT/US2016/030681 WO2016179226A1 (en) 2015-05-04 2016-05-04 Oncolytic hsv1 vector and methods of use

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JP2018518986A JP2018518986A (ja) 2018-07-19
JP2018518986A5 JP2018518986A5 (enExample) 2019-02-21
JP6865736B2 true JP6865736B2 (ja) 2021-04-28

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US (1) US10806761B2 (enExample)
EP (2) EP3981438A1 (enExample)
JP (1) JP6865736B2 (enExample)
KR (1) KR102705177B1 (enExample)
CN (1) CN108025088B (enExample)
AU (2) AU2016257910B2 (enExample)
CA (1) CA2988196C (enExample)
DK (1) DK3291841T3 (enExample)
ES (1) ES2903349T3 (enExample)
WO (1) WO2016179226A1 (enExample)

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WO2018169901A1 (en) * 2017-03-13 2018-09-20 Massachusetts Institute Of Technology Synthetic promoters
KR101974169B1 (ko) * 2018-08-10 2019-04-30 의료법인 성광의료재단 재조합 단순 헤르페스 바이러스 및 이의 제조방법
CN113164484A (zh) * 2018-11-29 2021-07-23 复诺健生物科技加拿大有限公司 具有降低的神经毒性的hsv载体
BR112021017651A2 (pt) * 2019-03-14 2021-11-16 Res Inst Nationwide Childrens Hospital Mutantes sinciciais oncolíticos de herpes simplex como potentes terapêuticas contra o câncer
KR102333650B1 (ko) * 2019-11-08 2021-12-01 한국해양과학기술원 신규한 인간 상피세포성장인자 융합 단백질 및 이의 용도

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US4683202A (en) 1985-03-28 1987-07-28 Cetus Corporation Process for amplifying nucleic acid sequences
US5728379A (en) 1994-06-23 1998-03-17 Georgetown University Tumor- or cell-specific herpes simplex virus replication
US5928906A (en) 1996-05-09 1999-07-27 Sequenom, Inc. Process for direct sequencing during template amplification
US6897057B1 (en) 1999-08-31 2005-05-24 The General Hospital Corporation Cell-specific and/or tumor-specific promoter retargeting of herpes γ 34.5 gene expression
WO2002053576A1 (en) 2001-01-05 2002-07-11 The General Hospital Corporation Viral delivery system for infectious transfer of large genomic dna inserts
WO2005080581A2 (en) 2004-02-17 2005-09-01 University Of Florida Research Foundation, Inc. Insulated herpesvirus-derived gene expression cassettes for sustained and regulatable gene expression
EP1731599A4 (en) * 2004-03-31 2009-12-23 Tomoki Todo METHOD FOR CONSTRUCTING RECOMBINANT HERPES SIMPLEX VIRUS
DE602007010514D1 (de) * 2006-12-18 2010-12-23 Koninkl Philips Electronics Nv Bildkomprimierung und dekomprimierung
US8450106B2 (en) * 2007-10-17 2013-05-28 The Ohio State University Research Foundation Oncolytic virus
WO2009148488A2 (en) * 2008-05-29 2009-12-10 The General Hospital Corporation Use of oncolytic herpes viruses for killing cancer stem cells
US10232002B1 (en) * 2012-11-14 2019-03-19 The Brigham And Women's Hospital Oncolytic HSV1 vectors and methods of using the same

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Publication number Publication date
CA2988196C (en) 2021-04-27
CA2988196A1 (en) 2016-11-10
CN108025088A (zh) 2018-05-11
EP3981438A1 (en) 2022-04-13
US20180133269A1 (en) 2018-05-17
KR102705177B1 (ko) 2024-09-11
EP3291841A1 (en) 2018-03-14
WO2016179226A1 (en) 2016-11-10
AU2021232778B2 (en) 2024-12-19
AU2016257910B2 (en) 2021-06-24
ES2903349T3 (es) 2022-04-01
CN108025088B (zh) 2021-08-10
KR20180037140A (ko) 2018-04-11
DK3291841T3 (da) 2022-01-10
US10806761B2 (en) 2020-10-20
JP2018518986A (ja) 2018-07-19
EP3291841B1 (en) 2021-10-20
AU2016257910A1 (en) 2017-12-21
AU2021232778A1 (en) 2021-10-14
EP3291841A4 (en) 2018-12-05

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