JP6822973B2 - 凝集の検出方法及びその方法を実施する際に使用する組成物 - Google Patents

凝集の検出方法及びその方法を実施する際に使用する組成物 Download PDF

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JP6822973B2
JP6822973B2 JP2017554311A JP2017554311A JP6822973B2 JP 6822973 B2 JP6822973 B2 JP 6822973B2 JP 2017554311 A JP2017554311 A JP 2017554311A JP 2017554311 A JP2017554311 A JP 2017554311A JP 6822973 B2 JP6822973 B2 JP 6822973B2
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antigen
polynucleotide
antibody
binding
sample
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JP2018512862A5 (https=
JP2018512862A (ja
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ピーター ロビンソン
ピーター ロビンソン
チェン‐ティン ツァイ
チェン‐ティン ツァイ
キャロリン ベルトッツィ
キャロリン ベルトッツィ
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University of California
University of California Los Angeles UCLA
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    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6804—Nucleic acid analysis using immunogens
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    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
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    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531—Production of immunochemical test materials
    • G—PHYSICS
    • G01—MEASURING; TESTING
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    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
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    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54306—Solid-phase reaction mechanisms
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/544—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being organic
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    • C12Q2525/00—Reactions involving modified oligonucleotides, nucleic acids, or nucleotides
    • C12Q2525/10—Modifications characterised by
    • C12Q2525/117—Modifications characterised by incorporating modified base
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    • C12Q2525/00—Reactions involving modified oligonucleotides, nucleic acids, or nucleotides
    • C12Q2525/10—Modifications characterised by
    • C12Q2525/155—Modifications characterised by incorporating/generating a new priming site
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    • C12Q2531/00—Reactions of nucleic acids characterised by
    • C12Q2531/10—Reactions of nucleic acids characterised by the purpose being amplify/increase the copy number of target nucleic acid
    • C12Q2531/113—PCR

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  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
JP2017554311A 2015-04-17 2016-04-15 凝集の検出方法及びその方法を実施する際に使用する組成物 Active JP6822973B2 (ja)

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Application Number Priority Date Filing Date Title
US201562149324P 2015-04-17 2015-04-17
US62/149,324 2015-04-17
PCT/US2016/027906 WO2016168711A1 (en) 2015-04-17 2016-04-15 Methods for detecting agglutination and compositions for use in practicing the same

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JP2018512862A JP2018512862A (ja) 2018-05-24
JP2018512862A5 JP2018512862A5 (https=) 2019-05-23
JP6822973B2 true JP6822973B2 (ja) 2021-01-27

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US (2) US11149296B2 (https=)
EP (2) EP3283638B1 (https=)
JP (1) JP6822973B2 (https=)
CN (1) CN107614699A (https=)
AU (1) AU2016249392A1 (https=)
BR (1) BR112017022329A2 (https=)
CA (1) CA2982998A1 (https=)
EA (1) EA201792289A1 (https=)
WO (1) WO2016168711A1 (https=)
ZA (1) ZA201707114B (https=)

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CN110869514A (zh) * 2017-03-30 2020-03-06 小利兰·斯坦福大学托管委员会 多重同型特异性抗体检测
CN109142730B (zh) * 2018-06-14 2021-04-23 郑州大学第一附属医院 一种肺癌标志物抗-psip1自身抗体及其应用
DE202020006093U1 (de) * 2019-05-06 2025-04-09 The Regents Of The University Of California Nicht-HLA-Marker der Transplantatabstoßung
CN111323590B (zh) * 2020-03-19 2022-04-22 福建省立医院 抗TIF1γ-IgA与抗TIF1γ-IgG作为联合诊断标志物在肺癌诊断中的应用
CN111398584A (zh) * 2020-03-20 2020-07-10 北京良芯生物科技发展有限公司 一种用于检测人类免疫缺陷病毒hiv1/2抗体的蛋白芯片及其制备方法
CN111499724A (zh) * 2020-04-15 2020-08-07 上海领潮生物新材料有限公司 一种s-腺苷同型半胱氨酸-鸡卵白蛋白偶联物的制备方法
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CN114316016B (zh) * 2021-12-14 2023-11-10 江苏浩欧博生物医药股份有限公司 一种Jo-1抗原生物素化的方法及抗Jo-1抗体检测试剂盒
CN115060912B (zh) * 2022-06-23 2024-02-02 南京浦光生物科技有限公司 检测目标抗体的试剂组合、试剂盒、检测系统及检测方法
EP4389913A1 (en) * 2022-12-23 2024-06-26 Universität Heidelberg A pcr-elisa analogous antibody-free method for detecting a target nucleic acid in a sample
CN116125076A (zh) * 2022-12-30 2023-05-16 广州医科大学 检测桥粒蛋白的试剂在制备肝纤维化的检测产品中的应用
CN118667920B (zh) * 2024-07-30 2024-11-12 北京华诺奥美基因生物科技有限公司 一种基于微流控的低丰度生物标志物的检测试剂盒、检测方法及其应用

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US12054768B2 (en) 2024-08-06
US11149296B2 (en) 2021-10-19
US20180100181A1 (en) 2018-04-12
EA201792289A1 (ru) 2018-04-30
US20210403978A1 (en) 2021-12-30
BR112017022329A2 (pt) 2018-07-17
WO2016168711A1 (en) 2016-10-20
JP2018512862A (ja) 2018-05-24
AU2016249392A1 (en) 2017-11-16
CA2982998A1 (en) 2016-10-20
EP3283638A4 (en) 2018-09-12
ZA201707114B (en) 2019-02-27
EP3283638B1 (en) 2022-06-08
CN107614699A (zh) 2018-01-19
EP3283638A1 (en) 2018-02-21
EP4123031A1 (en) 2023-01-25

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