JP6815864B2 - ピクセルアレイ医療デバイス及び方法 - Google Patents
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- JP6815864B2 JP6815864B2 JP2016520069A JP2016520069A JP6815864B2 JP 6815864 B2 JP6815864 B2 JP 6815864B2 JP 2016520069 A JP2016520069 A JP 2016520069A JP 2016520069 A JP2016520069 A JP 2016520069A JP 6815864 B2 JP6815864 B2 JP 6815864B2
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- A61B2017/3225—Skin grafting apparatus with processing of harvested tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F13/00—Bandages or dressings; Absorbent pads
- A61F13/00051—Accessories for dressings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/10—Hair or skin implants
Description
本出願は、2013年10月2日に出願された米国特許出願第61/885,734号の恩典を主張するものである。
本明細書における実施形態は、医療システム、器具若しくはデバイス、及び方法に関し、より具体的には、熱傷、皮膚欠損、及び植毛の外科的管理に適用される医療器具及び方法に関する。
老化過程は、垂れ下がった皮膚弛緩の進行によって最も可視的に表れる。この一生続く過程は、早くも20年代で現れる場合があり、その後何十年にもわたって徐々に悪化する。皮膚における垂れ下がった伸張又は加齢に関連する弛緩は、一部、皮膚の引張強度を減少させる進行性皮膚萎縮に起因することが、組織学的研究によって示されている。重力による下方向の力と併せられた場合、加齢に関連する皮膚萎縮は、結果として皮膚エンベロープの二次元的拡張を引き起こすであろう。この物理的−組織学的過程の臨床症状は、不必要な皮膚弛緩である。最も影響される領域は、頭及び首、上腕、大腿、乳房、下腹部、並びに膝領域である。全領域で最も可視的なのは、頭及び首である。この領域において、目立つ「雄七面鳥」と呼ばれる首の弛緩と顔の下側の「顎の垂れ肉」は、これらの領域における非審美的な皮膚の垂れ下がりに起因する。この審美的変形の頻度と社会的悪影響が、「フェイスリフト」という外科的手法の開発を促進した。異なる領域における他の関連する形成外科的手法は、腹壁形成術(Abdominoplasty)(腹部)、乳房固定術(Mastopexy)(乳房)、及び上腕形成術(Brachioplasty)(上腕)である。
本明細書において言及されるそれぞれの特許、特許出願、及び/又は刊行物は、あたかも個々の特許、特許出願、及び/又は刊行物のそれぞれが、具体的かつ個別的に、参照により本明細書に組み入れられることが示されている場合と同程度に、それらの全体が参照により本明細書に組み入れられる。
皮膚移植及び皮膚切除手法、並びに植毛手法のための、ピクセルアレイ医療システム、器具若しくはデバイス、及び方法について説明する。以下の説明では、本明細書における実施形態についての十分な理解を提供し、その説明を可能にするために、多くの特定の詳細について紹介する。しかしながら、これらの実施形態は、当該特定の詳細の1つ又は複数がなくても、又は他の要素、システムなどを伴っていても、実施することが可能であることを、当業者は認識するであろう。他の場合において、開示される実施形態の態様が不明瞭になることを避けるために、周知の構造又は作動については、図示されないか、又は詳細には説明されない。
102 アクセル/ハンドルアセンブリ
103 ブレードハンドル
104 ドラム回転要素
106 スカルペットアレイ
108 ブレード
110 粘着性膜
111 裏当て
112 ピクセルドラム採取器
115 フィーダー要素
200 ドラムアレイ薬物送達デバイス
202 ドラム/シリンダー
204 アクセル/ハンドルアセンブリ
206 ドラム回転要素
208 貯蔵所
210 シリンジプランジャー
212 針
214 注入チャンバー
216 接続チューブ
300 針アレイ薬物送達デバイス
302 シリンジ
304 シリンジプランジャー
306 使い捨て可能なアダプタ
308 シール
310 マニホールド
312 微細針
Claims (48)
- 採取パターンに対応する配置において配列された穿孔を含み、かつドナー部位及び被移植部位に位置決めされるように構成されたガイドプレートと;
前記採取パターンと揃うように構成された複数のスカルペットを含むスカルペットアレイを含むデバイスであって、前記複数のスカルペットが、前記ドナー部位において皮膚ピクセルを切開し、かつ前記被移植部位において皮膚欠損を生成するように構成される、デバイスと;
前記ドナー部位において前記切開された皮膚ピクセルを獲得するように構成される粘着性基材と、
を含むシステム。 - 前記ガイドプレートが、前記ドナー部位及び前記被移植部位の少なくとも一方の皮膚表面上に前記採取パターンをマークするために用いるために構成される、請求項1に記載のシステム。
- 前記スカルペットアレイが、前記デバイスに取り外し可能に連結される、請求項1に記載のシステム。
- 前記スカルペットアレイが使い捨て可能である、請求項1に記載のシステム。
- 前記スカルペットアレイの各スカルペットの形状が楕円形である、請求項1に記載のシステム。
- 前記スカルペットアレイの各スカルペットの形状が円形である、請求項1に記載のシステム。
- 前記スカルペットアレイの各スカルペットの形状が半円形である、請求項1に記載のシステム。
- 前記複数のスカルペットの各スカルペットが、テーパー状の表面を含む、請求項1に記載のシステム。
- 前記複数のスカルペットの各スカルペットが、少なくとも1つの先鋭な表面を含む、請求項1に記載のシステム。
- 前記スカルペットアレイが、穿孔力、衝突力、回転力、及び振動のうちの少なくとも1つを使用して、前記切開された皮膚ピクセルを生成する、請求項1に記載のシステム。
- 前記スカルペットアレイの複数のスカルペットが貫通孔を含む、請求項1に記載のシステム。
- 前記スカルペットアレイの各スカルペットの少なくとも1つの直径寸法は、およそ0.5ミリメートルから4.0ミリメートルの範囲である、請求項1に記載のシステム。
- 前記粘着性基材が柔軟な基材を含む、請求項1に記載のシステム。
- 前記粘着性基材が半多孔性膜を含む、請求項1に記載のシステム。
- 前記複数のスカルペットが、前記採取パターンに対応して配列される、請求項1に記載のシステム。
- 前記複数のスカルペットが、前記採取パターンと揃うように構成される、請求項15に記載のシステム。
- 前記スカルペットアレイが、前記採取パターンに従って前記ドナー部位に直接適用され、前記皮膚ピクセルが切開される、請求項16に記載のシステム。
- 前記粘着性基材が、前記被移植部位への前記切開された皮膚ピクセルの適用の間、前記切開された皮膚ピクセルを前記採取パターンに維持するように構成される、請求項17に記載のシステム。
- 前記スカルペットアレイが、前記採取パターンに従って前記被移植部位に直接適用され、前記皮膚欠損が生成される、請求項16に記載のシステム。
- 前記皮膚欠損が、前記採取パターンに従って生成される、請求項19に記載のシステム。
- 前記粘着性基材が、前記スカルペットアレイの適用に続いて前記標的部位への適用のために構成される、請求項15に記載のシステム。
- 前記ガイドプレートが、前記ドナー部位及び前記被移植部位の一方の皮膚表面上に直接位置決めされる、請求項21に記載のシステム。
- 前記ドナー部位の前記切開された皮膚ピクセル及び前記被移植部位の前記皮膚欠損が、前記配置で配列される、請求項21に記載のシステム。
- 前記ドナー部位の前記切開された皮膚ピクセルが第一配置を含み、前記被移植部位の前記皮膚欠損が第二配置を含み、前記第一配置と前記第二配置とが異なっている、請求項21に記載のシステム。
- 前記複数のスカルペットが、前記ガイドプレートの前記穿孔の少なくとも1つのセットに揃うように構成される、請求項21に記載のシステム。
- 前記スカルペットアレイが、前記ガイドプレートの穿孔の少なくとも1つのセットを通って前記ドナー部位に直接適用され、前記皮膚ピクセルが切開される、請求項16に記載のシステム。
- 前記粘着性基材が、前記被移植部位への移行、及び前記被移植部位への前記切開された皮膚ピクセルの適用の間、前記切開された皮膚ピクセルの相対位置決めを前記採取パターンに対応する配置に維持するように構成される、請求項26に記載のシステム。
- 前記スカルペットアレイが、前記穿孔の少なくとも1つのセットを通って前記被移植部位に直接適用され、前記皮膚欠損が生成される、請求項21に記載のシステム。
- 前記皮膚欠損が、前記配置に従って生成される、請求項28に記載のシステム。
- 前記ガイドプレートが、粘着性、剛性、半剛性、形状適合性、非形状適合性、及び非変形性のうちの少なくとも1つである、請求項21に記載のシステム。
- 前記ガイドプレートが、金属材料、プラスチック材料、高分子材料、膜状材料のうちの少なくとも1つを含む、請求項21に記載のシステム。
- 前記スカルペットアレイが、前記ドナー部位を含む下の皮膚表面に荷重を伝達するように構成され、前記皮膚ピクセルが、前記荷重の適用によって周囲的に切開される、請求項1に記載のシステム。
- 切断部材を含む、請求項1に記載のシステム。
- 前記切開された皮膚ピクセルが押し出され、前記押し出された皮膚ピクセルが、前記切断部材によって横切される、請求項33に記載のシステム。
- 前記粘着性基材が前記ドナー部位から引き上げられ、前記切開された皮膚ピクセルの底部が、前記切断部材によって横切される、請求項34に記載のシステム。
- 前記切断部材が、プレートフレームに連結される、請求項33に記載のシステム。
- 前記プレートフレームがガイドプレートに連結される、請求項36に記載のシステム。
- 前記粘着性基材が、ガイドプレート及び前記プレートフレームの少なくとも一方に連結される、請求項36に記載のシステム。
- 前記切開された皮膚ピクセルが、前記粘着性基材から前記被移植部位における前記皮膚欠損に直接適用される、請求項1に記載のシステム。
- 前記切開された皮膚ピクセルが、前記被移植部位における前記皮膚欠損に位置合わせされる、請求項39に記載のシステム。
- 各切開された皮膚ピクセルが、前記被移植部位における対応する皮膚欠損中に挿入される、請求項40に記載のシステム。
- 前記皮膚ピクセルが切開された後に第一包帯が前記ドナー部位に適用され、前記第一包帯が、前記ドナー部位をある方向に閉じる、請求項1に記載のシステム。
- 前記被移植部位に前記切開された皮膚ピクセルを適用した後に前記被移植部位に第二包帯が適用され、前記第二包帯が前記被移植部位において力を生じる、請求項1に記載のシステム。
- 前記切開された皮膚ピクセルが毛包を含む、請求項1に記載のシステム。
- 前記皮膚欠損が、前記被移植部位に挿入された前記切開された皮膚ピクセルにおける新生血管形成を誘発するように構成される、請求項1に記載のシステム。
- 前記皮膚欠損が、前記被移植部位に挿入された前記切開された皮膚ピクセルおける創傷治癒反応を誘発するように構成される、請求項1に記載のシステム。
- ある配置で配列された開口を含む採取パターンを生成するために用いるために構成されたガイドプレートであって、前記ガイドプレートが標的部位及び被移植部位に位置決めされるように構成される、ガイドプレートと;
前記配置で配列された複数のスカルペットを含むスカルペットアレイを含むデバイスであって、前記複数のスカルペットが、前記インジケーターの少なくとも1つのセットに揃うように構成され、前記複数のスカルペットが、標的部位において皮膚ピクセルを切開し、かつ前記被移植部位において皮膚欠損を生成するように構成される、デバイスと;
前記標的部位において前記切開された皮膚ピクセルを獲得し、前記被移植部位への前記切開された皮膚ピクセルの適用の間、前記配置を維持するように構成される粘着性基材と、
を含むシステム。 - ある配置で配列された開口を含む採取パターンを生成するために用いるために構成されたガイドプレートであって、前記ガイドプレートが標的部位及び被移植部位に位置決めされるように構成される、ガイドプレートと;
前記配置で配列された複数のスカルペットを含むスカルペットアレイを含むデバイスであって、前記複数のスカルペットが、前記インジケーターの少なくとも1つのセットに揃うように構成されて、標的部位において皮膚ピクセルを切開し、かつ前記被移植部位において皮膚欠損を生成するように構成される、デバイスと;
前記切開された皮膚ピクセルを捕捉して被移植部位に移行するように構成される膜と;
を含むシステム。
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US201462044102P | 2014-08-29 | 2014-08-29 | |
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US16/132,575 US11051844B2 (en) | 2010-12-17 | 2018-09-17 | Pixel array medical devices and methods |
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KR101991846B1 (ko) | 2016-07-04 | 2019-06-24 | 주식회사 엘지화학 | 음극 및 이의 제조방법 |
CA3037715A1 (en) | 2016-09-21 | 2018-03-29 | Cytrellis Biosystems, Inc. | Rapid skin treatment using microcoring |
KR102455542B1 (ko) | 2016-12-09 | 2022-10-18 | 한국전자통신연구원 | Fue 방식의 모낭 이송 및 이식 방법 |
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US11116540B2 (en) | 2021-09-14 |
AU2014329494A1 (en) | 2016-05-26 |
EP3052033B1 (en) | 2020-06-03 |
CN105828731A (zh) | 2016-08-03 |
MX2016004331A (es) | 2016-11-10 |
HK1225261A1 (zh) | 2017-09-08 |
US10080581B2 (en) | 2018-09-25 |
US20150230818A1 (en) | 2015-08-20 |
US20180250028A1 (en) | 2018-09-06 |
PH12016500602A1 (en) | 2016-06-13 |
EP3052033A2 (en) | 2016-08-10 |
PH12016500602B1 (en) | 2016-06-13 |
EP3052033A4 (en) | 2017-05-31 |
US20150230817A1 (en) | 2015-08-20 |
CA2926322A1 (en) | 2015-04-09 |
WO2015051164A2 (en) | 2015-04-09 |
US10335191B2 (en) | 2019-07-02 |
US10076354B2 (en) | 2018-09-18 |
SG11201602636PA (en) | 2016-05-30 |
JP2016531649A (ja) | 2016-10-13 |
US20200029991A1 (en) | 2020-01-30 |
BR112016007476A2 (pt) | 2017-09-12 |
CA2926322C (en) | 2022-10-18 |
WO2015051164A3 (en) | 2015-06-18 |
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