JP6802148B2 - スイギュウ由来ペプチド抗生物質療法 - Google Patents

スイギュウ由来ペプチド抗生物質療法 Download PDF

Info

Publication number
JP6802148B2
JP6802148B2 JP2017506818A JP2017506818A JP6802148B2 JP 6802148 B2 JP6802148 B2 JP 6802148B2 JP 2017506818 A JP2017506818 A JP 2017506818A JP 2017506818 A JP2017506818 A JP 2017506818A JP 6802148 B2 JP6802148 B2 JP 6802148B2
Authority
JP
Japan
Prior art keywords
group
sequence
trp
amino acid
peptide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
JP2017506818A
Other languages
English (en)
Japanese (ja)
Other versions
JP2017533177A (ja
JP2017533177A5 (enExample
Inventor
トナティウー メルガレホ ガルシア、ルイス
トナティウー メルガレホ ガルシア、ルイス
リンデ、アニカ
ヘンリー ラッシングトン、ジェラルド
ヘンリー ラッシングトン、ジェラルド
Original Assignee
セントール、インコーポレイテッド
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by セントール、インコーポレイテッド filed Critical セントール、インコーポレイテッド
Publication of JP2017533177A publication Critical patent/JP2017533177A/ja
Publication of JP2017533177A5 publication Critical patent/JP2017533177A5/ja
Application granted granted Critical
Publication of JP6802148B2 publication Critical patent/JP6802148B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N37/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids
    • A01N37/44—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing at least one carboxylic group or a thio analogue, or a derivative thereof, and a nitrogen atom attached to the same carbon skeleton by a single or double bond, this nitrogen atom not being a member of a derivative or of a thio analogue of a carboxylic group, e.g. amino-carboxylic acids
    • A01N37/46—N-acyl derivatives
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N47/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid
    • A01N47/40—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having a double or triple bond to nitrogen, e.g. cyanates, cyanamides
    • A01N47/42—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having a double or triple bond to nitrogen, e.g. cyanates, cyanamides containing —N=CX2 groups, e.g. isothiourea
    • A01N47/44—Guanidine; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N63/00—Biocides, pest repellants or attractants, or plant growth regulators containing microorganisms, viruses, microbial fungi, animals or substances produced by, or obtained from, microorganisms, viruses, microbial fungi or animals, e.g. enzymes or fermentates
    • A01N63/50—Isolated enzymes; Isolated proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/14—Drugs for genital or sexual disorders; Contraceptives for lactation disorders, e.g. galactorrhoea
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pest Control & Pesticides (AREA)
  • Agronomy & Crop Science (AREA)
  • Environmental Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Dentistry (AREA)
  • Plant Pathology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Virology (AREA)
  • Reproductive Health (AREA)
  • Pregnancy & Childbirth (AREA)
  • Gynecology & Obstetrics (AREA)
  • Endocrinology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
JP2017506818A 2014-08-04 2015-07-28 スイギュウ由来ペプチド抗生物質療法 Active JP6802148B2 (ja)

Applications Claiming Priority (11)

Application Number Priority Date Filing Date Title
US201462032737P 2014-08-04 2014-08-04
US62/032,737 2014-08-04
US14/483,083 US9029319B1 (en) 2014-08-04 2014-09-10 Water buffalo derived peptide antibiotic therapies
US14/483,083 2014-09-10
US14/678,558 2015-04-03
US14/678,558 US9273097B2 (en) 2014-08-04 2015-04-03 Water buffalo derived peptide antibiotic therapies
US14/692,518 2015-04-21
US14/692,518 US9163064B1 (en) 2014-08-04 2015-04-21 Water buffalo derived monomeric peptides containing proline for antibiotic therapies
US14/750,709 2015-06-25
US14/750,709 US9701716B2 (en) 2014-08-04 2015-06-25 Water buffalo derived dimeric peptide containing proline for antibiotic therapies
PCT/US2015/042435 WO2016022335A1 (en) 2014-08-04 2015-07-28 Water buffalo derived peptide antibiotic therapies

Publications (3)

Publication Number Publication Date
JP2017533177A JP2017533177A (ja) 2017-11-09
JP2017533177A5 JP2017533177A5 (enExample) 2018-06-07
JP6802148B2 true JP6802148B2 (ja) 2020-12-16

Family

ID=53038201

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2017506818A Active JP6802148B2 (ja) 2014-08-04 2015-07-28 スイギュウ由来ペプチド抗生物質療法

Country Status (21)

Country Link
US (4) US9029319B1 (enExample)
EP (1) EP3179855B1 (enExample)
JP (1) JP6802148B2 (enExample)
CN (1) CN108064131A (enExample)
AR (1) AR101416A1 (enExample)
AU (1) AU2015298629B2 (enExample)
BR (1) BR112017002166B1 (enExample)
CA (1) CA2956778C (enExample)
CY (1) CY1122747T1 (enExample)
DK (1) DK3179855T3 (enExample)
ES (1) ES2770705T3 (enExample)
HR (1) HRP20200195T1 (enExample)
HU (1) HUE048461T2 (enExample)
LT (1) LT3179855T (enExample)
MX (1) MX373912B (enExample)
PL (1) PL3179855T3 (enExample)
PT (1) PT3179855T (enExample)
RS (1) RS59987B1 (enExample)
SI (1) SI3179855T1 (enExample)
SM (1) SMT202000100T1 (enExample)
WO (1) WO2016022335A1 (enExample)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9029319B1 (en) * 2014-08-04 2015-05-12 Centaur, Inc. Water buffalo derived peptide antibiotic therapies
CN109553677B (zh) * 2018-11-30 2021-12-14 东北农业大学 基于两栖类蛙源抗菌肽的衍生肽w8及其制备方法和应用
KR102509412B1 (ko) * 2020-03-30 2023-03-14 애니젠 주식회사 신규한 항균 펩타이드 및 이의 용도
CN113831395B (zh) 2021-11-26 2022-02-22 中国海洋大学 一种重组抗菌肽TrSub、制备方法及其应用
CN119220434B (zh) * 2024-09-25 2025-05-30 青岛农业大学 一种具有高载硒活性的丁酸梭菌的菌制剂后生元及其应用

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1250355A1 (en) * 2000-01-21 2002-10-23 The Burnham Institute Chimeric prostate-homing peptides with pro-apoptotic activity
US8202835B2 (en) 2005-06-17 2012-06-19 Yitzchak Hillman Disease treatment via antimicrobial peptides or their inhibitors
DE102009007381A1 (de) * 2009-01-29 2010-08-05 Amp-Therapeutics Gmbh & Co. Kg Antibiotische Peptide
PT3115054T (pt) * 2009-02-06 2019-12-16 Technophage Investig E Desenvolvimento Em Biotecnologia Sa Fagos antibacterianos, péptidos fágicos e métodos de utilização dos mesmos
US9029319B1 (en) * 2014-08-04 2015-05-12 Centaur, Inc. Water buffalo derived peptide antibiotic therapies

Also Published As

Publication number Publication date
US9163064B1 (en) 2015-10-20
BR112017002166A2 (pt) 2018-01-16
HUE048461T2 (hu) 2020-07-28
JP2017533177A (ja) 2017-11-09
SI3179855T1 (sl) 2020-04-30
MX2017001566A (es) 2017-10-12
BR112017002166B1 (pt) 2022-08-16
US20160031940A1 (en) 2016-02-04
DK3179855T3 (da) 2020-02-17
EP3179855A1 (en) 2017-06-21
SMT202000100T1 (it) 2020-03-13
AU2015298629A1 (en) 2017-02-16
WO2016022335A1 (en) 2016-02-11
AR101416A1 (es) 2016-12-14
US20160031954A1 (en) 2016-02-04
US9273097B2 (en) 2016-03-01
EP3179855A4 (en) 2018-05-23
LT3179855T (lt) 2020-02-25
NZ728651A (en) 2021-11-26
RS59987B1 (sr) 2020-03-31
PL3179855T3 (pl) 2020-06-29
CN108064131A (zh) 2018-05-22
CA2956778A1 (en) 2016-02-11
EP3179855B1 (en) 2019-11-20
AU2015298629B2 (en) 2019-03-07
PT3179855T (pt) 2020-02-21
CA2956778C (en) 2021-10-26
CY1122747T1 (el) 2021-03-12
US9029319B1 (en) 2015-05-12
MX373912B (es) 2020-07-10
HRP20200195T1 (hr) 2020-08-07
ES2770705T3 (es) 2020-07-02
US9701716B2 (en) 2017-07-11

Similar Documents

Publication Publication Date Title
Lucidi et al. Pathogenicity and virulence of Acinetobacter baumannii: factors contributing to the fitness in healthcare settings and the infected host
JP6802148B2 (ja) スイギュウ由来ペプチド抗生物質療法
Peschel et al. Staphylococcal resistance to antimicrobial peptides of mammalian and bacterial origin
Sang et al. Antimicrobial peptides and bacteriocins: alternatives to traditional antibiotics
Myers et al. Skewed genomic variability in strains of the toxigenic bacterial pathogen, Clostridium perfringens
ES2683392T3 (es) Péptidos catiónicos cíclicos con actividad antimicrobiana
Howery et al. The Rcs regulon in Proteus mirabilis: implications for motility, biofilm formation, and virulence
Modak et al. Histone H3K14 and H4K8 hyperacetylation is associated with Escherichia coli-induced mastitis in mice
Wang et al. Hybrid phage displaying SLAQVKYTSASSI induces protection against Candida albicans challenge in BALB/c mice
Meng et al. Research advances of antimicrobial peptides and applications in food industry and agriculture
Mowbray et al. Gene expression of AvBD6-10 in broiler chickens is independent of AvBD6, 9, and 10 peptide potency
Bonar et al. Human skin microbiota-friendly lysostaphin
Higgs et al. Modification of chicken avian β-defensin-8 at positively selected amino acid sites enhances specific antimicrobial activity
CN103717744B (zh) 细菌形成的小菌素s，一种有效抵抗致病微生物如肠出血性大肠杆菌(ehec)的新抗微生物肽
FR2842210A1 (fr) Determinants de pathogenicite utilisables comme cibles pour l'elaboration de moyens de prevention et de controle d'infections bacteriennes et/ou de la dissemination systemique
JP2019529344A (ja) ランチビオティックバリアントおよびその使用
Cheng et al. Prevalence and isoforms of the pathogenicity island ETT2 among Escherichia coli isolates from colibacillosis in pigs and mastitis in cows
Leigh et al. The exploitation of the genome in the search for determinants of virulence in Streptococcus uberis
Kashyap Microbial metabolites: Peptides of diverse structure and function
NZ728651B2 (en) Water buffalo derived peptide antibiotic therapies
Mi et al. Evolutionary dynamics and regulatory site analysis of AMP family genes in cattle and sheep
Pridgeon et al. Identification of in vitro upregulated genes in a modified live vaccine strain of Edwardsiella ictaluri compared to a virulent parent strain
Fakheri et al. Small but potent killers
Lu Identification of virulence factors in Edwardsiella ictaluri
Singh DEVELOPMENT OF NOVEL SYNTHETIC PEPTIDE ANTIBIOTICSAND EVALUATION OFTHERAPEUTIC POTENTIAL IN MURINE MASTITIS MODEL

Legal Events

Date Code Title Description
A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A821

Effective date: 20170330

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20170515

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20180413

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20180413

A977 Report on retrieval

Free format text: JAPANESE INTERMEDIATE CODE: A971007

Effective date: 20181221

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20190108

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20190408

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20190610

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20190626

RD03 Notification of appointment of power of attorney

Free format text: JAPANESE INTERMEDIATE CODE: A7423

Effective date: 20191021

RD04 Notification of resignation of power of attorney

Free format text: JAPANESE INTERMEDIATE CODE: A7424

Effective date: 20191021

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A821

Effective date: 20191021

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20191119

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20200219

A02 Decision of refusal

Free format text: JAPANESE INTERMEDIATE CODE: A02

Effective date: 20200428

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20200828

C60 Trial request (containing other claim documents, opposition documents)

Free format text: JAPANESE INTERMEDIATE CODE: C60

Effective date: 20200828

A911 Transfer to examiner for re-examination before appeal (zenchi)

Free format text: JAPANESE INTERMEDIATE CODE: A911

Effective date: 20200925

C21 Notice of transfer of a case for reconsideration by examiners before appeal proceedings

Free format text: JAPANESE INTERMEDIATE CODE: C21

Effective date: 20200929

TRDD Decision of grant or rejection written
A01 Written decision to grant a patent or to grant a registration (utility model)

Free format text: JAPANESE INTERMEDIATE CODE: A01

Effective date: 20201027

A61 First payment of annual fees (during grant procedure)

Free format text: JAPANESE INTERMEDIATE CODE: A61

Effective date: 20201126

R150 Certificate of patent or registration of utility model

Ref document number: 6802148

Country of ref document: JP

Free format text: JAPANESE INTERMEDIATE CODE: R150

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250