CA2956778C - Water buffalo derived peptide antibiotic therapies - Google Patents

Water buffalo derived peptide antibiotic therapies Download PDF

Info

Publication number
CA2956778C
CA2956778C CA2956778A CA2956778A CA2956778C CA 2956778 C CA2956778 C CA 2956778C CA 2956778 A CA2956778 A CA 2956778A CA 2956778 A CA2956778 A CA 2956778A CA 2956778 C CA2956778 C CA 2956778C
Authority
CA
Canada
Prior art keywords
group
trp
leu
ile
antimicrobial
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CA2956778A
Other languages
English (en)
French (fr)
Other versions
CA2956778A1 (en
Inventor
Luis Tonatiuh Melgarejo GARCIA
Annika LINDE
Gerald Henry LUSHINGTON
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Centaur Inc
Original Assignee
Centaur Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Centaur Inc filed Critical Centaur Inc
Publication of CA2956778A1 publication Critical patent/CA2956778A1/en
Application granted granted Critical
Publication of CA2956778C publication Critical patent/CA2956778C/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N37/00Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids
    • A01N37/44Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing at least one carboxylic group or a thio analogue, or a derivative thereof, and a nitrogen atom attached to the same carbon skeleton by a single or double bond, this nitrogen atom not being a member of a derivative or of a thio analogue of a carboxylic group, e.g. amino-carboxylic acids
    • A01N37/46N-acyl derivatives
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N47/00Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid
    • A01N47/40Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having a double or triple bond to nitrogen, e.g. cyanates, cyanamides
    • A01N47/42Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having a double or triple bond to nitrogen, e.g. cyanates, cyanamides containing —N=CX2 groups, e.g. isothiourea
    • A01N47/44Guanidine; Derivatives thereof
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N63/00Biocides, pest repellants or attractants, or plant growth regulators containing microorganisms, viruses, microbial fungi, animals or substances produced by, or obtained from, microorganisms, viruses, microbial fungi or animals, e.g. enzymes or fermentates
    • A01N63/50Isolated enzymes; Isolated proteins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/14Drugs for genital or sexual disorders; Contraceptives for lactation disorders, e.g. galactorrhoea
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10Antimycotics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/08Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Wood Science & Technology (AREA)
  • Environmental Sciences (AREA)
  • Dentistry (AREA)
  • Plant Pathology (AREA)
  • Pest Control & Pesticides (AREA)
  • Agronomy & Crop Science (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • Microbiology (AREA)
  • Oncology (AREA)
  • Biotechnology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pregnancy & Childbirth (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
CA2956778A 2014-08-04 2015-07-28 Water buffalo derived peptide antibiotic therapies Active CA2956778C (en)

Applications Claiming Priority (11)

Application Number Priority Date Filing Date Title
US201462032737P 2014-08-04 2014-08-04
US62/032,737 2014-08-04
US14/483,083 US9029319B1 (en) 2014-08-04 2014-09-10 Water buffalo derived peptide antibiotic therapies
US14/483,083 2014-09-10
US14/678,558 2015-04-03
US14/678,558 US9273097B2 (en) 2014-08-04 2015-04-03 Water buffalo derived peptide antibiotic therapies
US14/692,518 2015-04-21
US14/692,518 US9163064B1 (en) 2014-08-04 2015-04-21 Water buffalo derived monomeric peptides containing proline for antibiotic therapies
US14/750,709 2015-06-25
US14/750,709 US9701716B2 (en) 2014-08-04 2015-06-25 Water buffalo derived dimeric peptide containing proline for antibiotic therapies
PCT/US2015/042435 WO2016022335A1 (en) 2014-08-04 2015-07-28 Water buffalo derived peptide antibiotic therapies

Publications (2)

Publication Number Publication Date
CA2956778A1 CA2956778A1 (en) 2016-02-11
CA2956778C true CA2956778C (en) 2021-10-26

Family

ID=53038201

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2956778A Active CA2956778C (en) 2014-08-04 2015-07-28 Water buffalo derived peptide antibiotic therapies

Country Status (21)

Country Link
US (4) US9029319B1 (enExample)
EP (1) EP3179855B1 (enExample)
JP (1) JP6802148B2 (enExample)
CN (1) CN108064131A (enExample)
AR (1) AR101416A1 (enExample)
AU (1) AU2015298629B2 (enExample)
BR (1) BR112017002166B1 (enExample)
CA (1) CA2956778C (enExample)
CY (1) CY1122747T1 (enExample)
DK (1) DK3179855T3 (enExample)
ES (1) ES2770705T3 (enExample)
HR (1) HRP20200195T1 (enExample)
HU (1) HUE048461T2 (enExample)
LT (1) LT3179855T (enExample)
MX (1) MX373912B (enExample)
PL (1) PL3179855T3 (enExample)
PT (1) PT3179855T (enExample)
RS (1) RS59987B1 (enExample)
SI (1) SI3179855T1 (enExample)
SM (1) SMT202000100T1 (enExample)
WO (1) WO2016022335A1 (enExample)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9029319B1 (en) 2014-08-04 2015-05-12 Centaur, Inc. Water buffalo derived peptide antibiotic therapies
CN109553677B (zh) * 2018-11-30 2021-12-14 东北农业大学 基于两栖类蛙源抗菌肽的衍生肽w8及其制备方法和应用
US20230287044A1 (en) * 2020-03-30 2023-09-14 Anygen Co., Ltd. Novel antibacterial peptide and use thereof
CN113831395B (zh) 2021-11-26 2022-02-22 中国海洋大学 一种重组抗菌肽TrSub、制备方法及其应用
CN119220434B (zh) * 2024-09-25 2025-05-30 青岛农业大学 一种具有高载硒活性的丁酸梭菌的菌制剂后生元及其应用

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2003520808A (ja) * 2000-01-21 2003-07-08 ザ バーナム インスティチュート プロアポトーシス活性を有するキメラ前立腺ホーミングペプチド
US8202835B2 (en) 2005-06-17 2012-06-19 Yitzchak Hillman Disease treatment via antimicrobial peptides or their inhibitors
DE102009007381A1 (de) * 2009-01-29 2010-08-05 Amp-Therapeutics Gmbh & Co. Kg Antibiotische Peptide
CN102348460B (zh) * 2009-02-06 2015-08-26 抗菌技术,生物技术研究与发展股份有限公司 抗菌噬菌体、噬菌体肽及其使用方法
US9029319B1 (en) 2014-08-04 2015-05-12 Centaur, Inc. Water buffalo derived peptide antibiotic therapies

Also Published As

Publication number Publication date
US9029319B1 (en) 2015-05-12
EP3179855A1 (en) 2017-06-21
CY1122747T1 (el) 2021-03-12
CA2956778A1 (en) 2016-02-11
AR101416A1 (es) 2016-12-14
LT3179855T (lt) 2020-02-25
AU2015298629A1 (en) 2017-02-16
US20160031940A1 (en) 2016-02-04
PT3179855T (pt) 2020-02-21
SI3179855T1 (sl) 2020-04-30
PL3179855T3 (pl) 2020-06-29
HRP20200195T1 (hr) 2020-08-07
NZ728651A (en) 2021-11-26
AU2015298629B2 (en) 2019-03-07
CN108064131A (zh) 2018-05-22
US9163064B1 (en) 2015-10-20
JP6802148B2 (ja) 2020-12-16
RS59987B1 (sr) 2020-03-31
WO2016022335A1 (en) 2016-02-11
US20160031954A1 (en) 2016-02-04
SMT202000100T1 (it) 2020-03-13
MX2017001566A (es) 2017-10-12
MX373912B (es) 2020-07-10
ES2770705T3 (es) 2020-07-02
JP2017533177A (ja) 2017-11-09
EP3179855B1 (en) 2019-11-20
HUE048461T2 (hu) 2020-07-28
DK3179855T3 (da) 2020-02-17
BR112017002166B1 (pt) 2022-08-16
US9273097B2 (en) 2016-03-01
US9701716B2 (en) 2017-07-11
BR112017002166A2 (pt) 2018-01-16
EP3179855A4 (en) 2018-05-23

Similar Documents

Publication Publication Date Title
CA2956778C (en) Water buffalo derived peptide antibiotic therapies
Peschel et al. Staphylococcal resistance to antimicrobial peptides of mammalian and bacterial origin
Le et al. Intracellular targeting mechanisms by antimicrobial peptides
Sang et al. Antimicrobial peptides and bacteriocins: alternatives to traditional antibiotics
JP6964577B2 (ja) 抗菌性ペプチド及びその使用方法
ES2683392T3 (es) Péptidos catiónicos cíclicos con actividad antimicrobiana
Lehrer et al. Defensins: endogenous antibiotic peptides from human leukocytes
van der Goot Pore-forming toxins
Mechkarska et al. Antimicrobial peptides with therapeutic potential from skin secretions of the Marsabit clawed frog Xenopus borealis (Pipidae)
Mowbray et al. Gene expression of AvBD6-10 in broiler chickens is independent of AvBD6, 9, and 10 peptide potency
Almofti et al. Impact of erythromycin resistance on the virulence properties and fitness of Campylobacter jejuni
JP2019529344A (ja) ランチビオティックバリアントおよびその使用
JP2006519217A (ja) 抗菌剤
Bala et al. Antimicrobial peptides: a review
NZ728651B2 (en) Water buffalo derived peptide antibiotic therapies
Amano SEp22, Salmonella Dps, a key molecule bearing both pathogenicity and resistance to environmental stresses in Salmonella
Umnyakova et al. Peptides and antibiotic resistance
Fakheri et al. Small but potent killers
Teso-Pérez et al. Enterocin Cross-Resistance Mediated by ABC Transport Systems. Microorganisms 2021, 9, 1411
Popitool Potential of antimicrobial peptides against bacterial pathogens causing bovine mastitis
Granata Membrane proteins and virulence pathways: new approaches to design antimicrobial peptides
WO2020077470A1 (es) Polipéptido antibacteriano, composición que lo comprende y uso para tratar infecciones bacterianas.
Andrews-Polymenis et al. Subspecies IIIa and IIIb Salmonellae Are
dos Santos Role of the murine cathelicidin in the infection with Mycobacterium avium
WO2003027140A2 (en) Identification of s. typhimurium genes by software-based genome comparison

Legal Events

Date Code Title Description
EEER Examination request

Effective date: 20190329