CN108064131A - 水牛来源的肽抗菌治疗剂 - Google Patents

水牛来源的肽抗菌治疗剂 Download PDF

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Publication number
CN108064131A
CN108064131A CN201580052880.XA CN201580052880A CN108064131A CN 108064131 A CN108064131 A CN 108064131A CN 201580052880 A CN201580052880 A CN 201580052880A CN 108064131 A CN108064131 A CN 108064131A
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CN
China
Prior art keywords
group
trp
arg
leu
antimicrobial
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201580052880.XA
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English (en)
Chinese (zh)
Inventor
路易斯·托纳蒂乌·梅尔加雷霍·加西亚
安尼卡·林德
杰拉德·亨利·勒欣顿
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San Tur Co
Original Assignee
San Tur Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by San Tur Co filed Critical San Tur Co
Publication of CN108064131A publication Critical patent/CN108064131A/zh
Pending legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N37/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids
    • A01N37/44—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing at least one carboxylic group or a thio analogue, or a derivative thereof, and a nitrogen atom attached to the same carbon skeleton by a single or double bond, this nitrogen atom not being a member of a derivative or of a thio analogue of a carboxylic group, e.g. amino-carboxylic acids
    • A01N37/46—N-acyl derivatives
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N47/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid
    • A01N47/40—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having a double or triple bond to nitrogen, e.g. cyanates, cyanamides
    • A01N47/42—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having a double or triple bond to nitrogen, e.g. cyanates, cyanamides containing —N=CX2 groups, e.g. isothiourea
    • A01N47/44—Guanidine; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N63/00—Biocides, pest repellants or attractants, or plant growth regulators containing microorganisms, viruses, microbial fungi, animals or substances produced by, or obtained from, microorganisms, viruses, microbial fungi or animals, e.g. enzymes or fermentates
    • A01N63/50—Isolated enzymes; Isolated proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/14—Drugs for genital or sexual disorders; Contraceptives for lactation disorders, e.g. galactorrhoea
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pest Control & Pesticides (AREA)
  • Agronomy & Crop Science (AREA)
  • Environmental Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Dentistry (AREA)
  • Plant Pathology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Virology (AREA)
  • Reproductive Health (AREA)
  • Pregnancy & Childbirth (AREA)
  • Gynecology & Obstetrics (AREA)
  • Endocrinology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
CN201580052880.XA 2014-08-04 2015-07-28 水牛来源的肽抗菌治疗剂 Pending CN108064131A (zh)

Applications Claiming Priority (11)

Application Number Priority Date Filing Date Title
US201462032737P 2014-08-04 2014-08-04
US62/032,737 2014-08-04
US14/483,083 US9029319B1 (en) 2014-08-04 2014-09-10 Water buffalo derived peptide antibiotic therapies
US14/483,083 2014-09-10
US14/678,558 2015-04-03
US14/678,558 US9273097B2 (en) 2014-08-04 2015-04-03 Water buffalo derived peptide antibiotic therapies
US14/692,518 2015-04-21
US14/692,518 US9163064B1 (en) 2014-08-04 2015-04-21 Water buffalo derived monomeric peptides containing proline for antibiotic therapies
US14/750,709 US9701716B2 (en) 2014-08-04 2015-06-25 Water buffalo derived dimeric peptide containing proline for antibiotic therapies
US14/750,709 2015-06-25
PCT/US2015/042435 WO2016022335A1 (en) 2014-08-04 2015-07-28 Water buffalo derived peptide antibiotic therapies

Publications (1)

Publication Number Publication Date
CN108064131A true CN108064131A (zh) 2018-05-22

Family

ID=53038201

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201580052880.XA Pending CN108064131A (zh) 2014-08-04 2015-07-28 水牛来源的肽抗菌治疗剂

Country Status (21)

Country Link
US (4) US9029319B1 (enExample)
EP (1) EP3179855B1 (enExample)
JP (1) JP6802148B2 (enExample)
CN (1) CN108064131A (enExample)
AR (1) AR101416A1 (enExample)
AU (1) AU2015298629B2 (enExample)
BR (1) BR112017002166B1 (enExample)
CA (1) CA2956778C (enExample)
CY (1) CY1122747T1 (enExample)
DK (1) DK3179855T3 (enExample)
ES (1) ES2770705T3 (enExample)
HR (1) HRP20200195T1 (enExample)
HU (1) HUE048461T2 (enExample)
LT (1) LT3179855T (enExample)
MX (1) MX373912B (enExample)
PL (1) PL3179855T3 (enExample)
PT (1) PT3179855T (enExample)
RS (1) RS59987B1 (enExample)
SI (1) SI3179855T1 (enExample)
SM (1) SMT202000100T1 (enExample)
WO (1) WO2016022335A1 (enExample)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9029319B1 (en) * 2014-08-04 2015-05-12 Centaur, Inc. Water buffalo derived peptide antibiotic therapies
CN109553677B (zh) * 2018-11-30 2021-12-14 东北农业大学 基于两栖类蛙源抗菌肽的衍生肽w8及其制备方法和应用
EP4129064A4 (en) * 2020-03-30 2023-12-13 Anygen Co., Ltd. NEW ANTIBACTERIAL PEPTIDE AND USE THEREOF
CN113831395B (zh) 2021-11-26 2022-02-22 中国海洋大学 一种重组抗菌肽TrSub、制备方法及其应用
CN119220434B (zh) * 2024-09-25 2025-05-30 青岛农业大学 一种具有高载硒活性的丁酸梭菌的菌制剂后生元及其应用

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010086401A1 (de) * 2009-01-29 2010-08-05 Amp-Therapeutics Gmbh & Co. Kg Antibiotische peptide
CN102348460A (zh) * 2009-02-06 2012-02-08 抗菌技术,生物技术研究与发展股份有限公司 抗菌噬菌体、噬菌体肽及其使用方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1250355A1 (en) * 2000-01-21 2002-10-23 The Burnham Institute Chimeric prostate-homing peptides with pro-apoptotic activity
US8202835B2 (en) 2005-06-17 2012-06-19 Yitzchak Hillman Disease treatment via antimicrobial peptides or their inhibitors
US9029319B1 (en) * 2014-08-04 2015-05-12 Centaur, Inc. Water buffalo derived peptide antibiotic therapies

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010086401A1 (de) * 2009-01-29 2010-08-05 Amp-Therapeutics Gmbh & Co. Kg Antibiotische peptide
CN102348460A (zh) * 2009-02-06 2012-02-08 抗菌技术,生物技术研究与发展股份有限公司 抗菌噬菌体、噬菌体肽及其使用方法

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
JONSON ET AL.: "A critical view on conservative mutations", 《PROTEIN ENGINEERING》 *

Also Published As

Publication number Publication date
WO2016022335A1 (en) 2016-02-11
DK3179855T3 (da) 2020-02-17
SI3179855T1 (sl) 2020-04-30
ES2770705T3 (es) 2020-07-02
US9701716B2 (en) 2017-07-11
EP3179855A1 (en) 2017-06-21
US9273097B2 (en) 2016-03-01
LT3179855T (lt) 2020-02-25
US20160031954A1 (en) 2016-02-04
BR112017002166A2 (pt) 2018-01-16
CA2956778A1 (en) 2016-02-11
BR112017002166B1 (pt) 2022-08-16
AU2015298629A1 (en) 2017-02-16
JP6802148B2 (ja) 2020-12-16
AU2015298629B2 (en) 2019-03-07
RS59987B1 (sr) 2020-03-31
PT3179855T (pt) 2020-02-21
CA2956778C (en) 2021-10-26
EP3179855A4 (en) 2018-05-23
NZ728651A (en) 2021-11-26
MX373912B (es) 2020-07-10
EP3179855B1 (en) 2019-11-20
HRP20200195T1 (hr) 2020-08-07
US20160031940A1 (en) 2016-02-04
CY1122747T1 (el) 2021-03-12
JP2017533177A (ja) 2017-11-09
US9029319B1 (en) 2015-05-12
MX2017001566A (es) 2017-10-12
HUE048461T2 (hu) 2020-07-28
AR101416A1 (es) 2016-12-14
PL3179855T3 (pl) 2020-06-29
SMT202000100T1 (it) 2020-03-13
US9163064B1 (en) 2015-10-20

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Application publication date: 20180522