JP6755975B2 - 明視野像シミュレーションのためのシステム - Google Patents

明視野像シミュレーションのためのシステム Download PDF

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JP6755975B2
JP6755975B2 JP2018563572A JP2018563572A JP6755975B2 JP 6755975 B2 JP6755975 B2 JP 6755975B2 JP 2018563572 A JP2018563572 A JP 2018563572A JP 2018563572 A JP2018563572 A JP 2018563572A JP 6755975 B2 JP6755975 B2 JP 6755975B2
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image
fluorescence
fluorescent
color
biomarkers
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JP2019530847A5 (enExample
JP2019530847A (ja
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エルダド クライマン，
エルダド クライマン，
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エフ・ホフマン−ラ・ロシュ・アクチェンゲゼルシャフト
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    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T7/00—Image analysis
    • G06T7/0002—Inspection of images, e.g. flaw detection
    • G06T7/0012—Biomedical image inspection
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/645—Specially adapted constructive features of fluorimeters
    • G01N21/6456—Spatial resolved fluorescence measurements; Imaging
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T11/00—2D [Two Dimensional] image generation
    • G06T11/001—Texturing; Colouring; Generation of texture or colour
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T5/00—Image enhancement or restoration
    • G06T5/50—Image enhancement or restoration using two or more images, e.g. averaging or subtraction
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
    • G01N2021/6439—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes" with indicators, stains, dyes, tags, labels, marks
    • G01N2021/6441—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes" with indicators, stains, dyes, tags, labels, marks with two or more labels
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T2207/00—Indexing scheme for image analysis or image enhancement
    • G06T2207/10—Image acquisition modality
    • G06T2207/10032—Satellite or aerial image; Remote sensing
    • G06T2207/10036—Multispectral image; Hyperspectral image
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T2207/00—Indexing scheme for image analysis or image enhancement
    • G06T2207/10—Image acquisition modality
    • G06T2207/10056—Microscopic image
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T2207/00—Indexing scheme for image analysis or image enhancement
    • G06T2207/10—Image acquisition modality
    • G06T2207/10064—Fluorescence image
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T2207/00—Indexing scheme for image analysis or image enhancement
    • G06T2207/20—Special algorithmic details
    • G06T2207/20212—Image combination
    • G06T2207/20221—Image fusion; Image merging
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T2207/00—Indexing scheme for image analysis or image enhancement
    • G06T2207/30—Subject of image; Context of image processing
    • G06T2207/30004—Biomedical image processing
    • G06T2207/30024—Cell structures in vitro; Tissue sections in vitro
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T2207/00—Indexing scheme for image analysis or image enhancement
    • G06T2207/30—Subject of image; Context of image processing
    • G06T2207/30204—Marker

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  • Engineering & Computer Science (AREA)
  • General Physics & Mathematics (AREA)
  • Physics & Mathematics (AREA)
  • Theoretical Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • Medical Informatics (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • Quality & Reliability (AREA)
  • Radiology & Medical Imaging (AREA)
  • Analytical Chemistry (AREA)
  • Pathology (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
JP2018563572A 2016-06-10 2017-06-09 明視野像シミュレーションのためのシステム Active JP6755975B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP16174025.3 2016-06-10
EP16174025 2016-06-10
PCT/EP2017/064193 WO2017212055A1 (en) 2016-06-10 2017-06-09 System for bright field image simulation

Publications (3)

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JP2019530847A JP2019530847A (ja) 2019-10-24
JP2019530847A5 JP2019530847A5 (enExample) 2020-06-11
JP6755975B2 true JP6755975B2 (ja) 2020-09-16

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JP2018563572A Active JP6755975B2 (ja) 2016-06-10 2017-06-09 明視野像シミュレーションのためのシステム

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US (1) US10846848B2 (enExample)
EP (1) EP3469548B1 (enExample)
JP (1) JP6755975B2 (enExample)
CN (1) CN109313798B (enExample)
WO (1) WO2017212055A1 (enExample)

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JP2020020791A (ja) * 2018-07-24 2020-02-06 ソニー株式会社 情報処理装置、情報処理方法、情報処理システム、およびプログラム
WO2020022394A1 (en) * 2018-07-24 2020-01-30 Sony Corporation Information processing apparatus and microscope for separating the fluorescence of a fluorescent reageant from the autofluorescence of a specimen
CN112534439A (zh) 2018-07-27 2021-03-19 文塔纳医疗系统公司 用于自动化原位杂交分析的系统
CN112288783B (zh) * 2018-08-22 2021-06-29 深圳市真迈生物科技有限公司 基于图像构建测序模板的方法、碱基识别方法和装置
WO2020039520A1 (ja) * 2018-08-22 2020-02-27 オリンパス株式会社 画像処理装置、撮像システム、画像処理装置の作動方法、及び画像処理装置の作動プログラム
US10753875B1 (en) * 2019-01-31 2020-08-25 Rarecyte, Inc. Spectral unmixing of spectroscopic emission images
US20220148177A1 (en) * 2019-06-02 2022-05-12 Essenlix Corporation Fast staining of biomaterials enhanced by image processing and artificial intelligence
CN111380843A (zh) * 2019-06-28 2020-07-07 南京大学 一种高灵敏的可见-近红外双通道激光荧光显微镜的装置设计及其成像方法
EP3767587B1 (de) * 2019-07-19 2024-10-23 Euroimmun Medizinische Labordiagnostika AG Detektion von präsenzen unterschiedlicher antinukleärer antikörper-fluoreszenzmustertypen und vorrichtung hierfür
CN110689477B (zh) * 2019-09-07 2023-01-10 创新奇智(重庆)科技有限公司 一种通用的瑕疵图像模拟方法
JP7404831B2 (ja) * 2019-12-02 2023-12-26 日本電気株式会社 ソーナー画像伝送装置、システム、ソーナー画像受信装置、ソーナー画像伝送方法、及びプログラム
AU2020395256B2 (en) * 2019-12-05 2025-10-16 Tempus Ai, Inc. Large scale organoid analysis
JP2021124861A (ja) * 2020-02-04 2021-08-30 ソニーグループ株式会社 解析装置、解析方法、解析プログラム及び診断支援システム
EP3889886A1 (en) * 2020-04-01 2021-10-06 Leica Instruments (Singapore) Pte. Ltd. Systems, methods and computer programs for a microscope system and for determining a transformation function
JP7647751B2 (ja) * 2020-06-30 2025-03-18 ソニーグループ株式会社 情報処理装置、情報処理方法、プログラム、顕微鏡システム及び解析システム
JP2023534988A (ja) * 2020-07-20 2023-08-15 アコヤ・バイオサイエンシズ・インコーポレイテッド 組織試料処理及びイメージング
CN111766125A (zh) * 2020-07-29 2020-10-13 广州金域医学检验中心有限公司 利用荧光淬灭时间差进行的染色方法及自动染色装置、设备和介质
IL300699A (en) * 2020-08-18 2023-04-01 Agilent Technologies Inc Tissue staining and continuous imaging of biological samples for deep learning, image analysis, and virtual staining
DE102021204805A1 (de) * 2021-05-11 2022-11-17 Carl Zeiss Microscopy Gmbh Bewertungsverfahren für Simulationsmodelle in der Mikroskopie
GB2607604A (en) * 2021-06-08 2022-12-14 Solentim Ltd Brightfield and fluorescence image comparison
WO2022265883A1 (en) * 2021-06-17 2022-12-22 Ventana Medical Systems, Inc. Digital synthesis of histological stains using multiplexed immunofluorescence imaging
CN113539368B (zh) * 2021-08-30 2023-02-03 长春理工大学 荧光图像信号数据存储与颜色分类方法
CN113933275B (zh) * 2021-10-13 2023-10-24 季华实验室 基于生物成像的定量分析方法、分离方法、装置及设备
EP4177826A1 (en) 2021-11-05 2023-05-10 Technische Universität Dresden Method and system for simulating and predicting histological staining of a tissue section

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US8269827B2 (en) 2009-09-29 2012-09-18 General Electric Company System and methods for mapping fluorescent images into a bright field color space
CN102667473B (zh) * 2009-10-12 2016-06-08 文塔纳医疗系统公司 用于组织的增强的病理学测定和多分析物检测的多模态对比和明场背景再现
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Also Published As

Publication number Publication date
WO2017212055A1 (en) 2017-12-14
CN109313798B (zh) 2022-04-01
US10846848B2 (en) 2020-11-24
US20200327657A1 (en) 2020-10-15
EP3469548A1 (en) 2019-04-17
CN109313798A (zh) 2019-02-05
JP2019530847A (ja) 2019-10-24
EP3469548B1 (en) 2020-05-13

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