JP6750140B2 - 直腸結腸がんを早期検出するための方法 - Google Patents

直腸結腸がんを早期検出するための方法 Download PDF

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JP6750140B2
JP6750140B2 JP2017529971A JP2017529971A JP6750140B2 JP 6750140 B2 JP6750140 B2 JP 6750140B2 JP 2017529971 A JP2017529971 A JP 2017529971A JP 2017529971 A JP2017529971 A JP 2017529971A JP 6750140 B2 JP6750140 B2 JP 6750140B2
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デイビス,ジェラード・ジェイ
ガウェル,スーザン・エイチ
ヤン,シャオチン
ニルスン,ハンス・ヨーエン
クリステンセン,イブ・ヤーレ
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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57407Specifically defined cancers
    • G01N33/57419Specifically defined cancers of colon
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N5/10X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/46Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates
    • G01N2333/47Assays involving proteins of known structure or function as defined in the subgroups
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/46Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates
    • G01N2333/47Assays involving proteins of known structure or function as defined in the subgroups
    • G01N2333/4701Details
    • G01N2333/4737C-reactive protein
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/46Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates
    • G01N2333/47Assays involving proteins of known structure or function as defined in the subgroups
    • G01N2333/4701Details
    • G01N2333/4742Keratin; Cytokeratin

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  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
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  • Hospice & Palliative Care (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
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  • Investigating Or Analysing Biological Materials (AREA)
  • Peptides Or Proteins (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2017529971A 2014-08-22 2015-08-21 直腸結腸がんを早期検出するための方法 Expired - Fee Related JP6750140B2 (ja)

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US201462040874P 2014-08-22 2014-08-22
US62/040,874 2014-08-22
PCT/US2015/046301 WO2016029117A1 (en) 2014-08-22 2015-08-21 Methods for the early detection of colorectal cancer

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JP2017532577A JP2017532577A (ja) 2017-11-02
JP2017532577A5 JP2017532577A5 (enExample) 2018-10-04
JP6750140B2 true JP6750140B2 (ja) 2020-09-02

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US (1) US20160178631A1 (enExample)
EP (1) EP3183578B8 (enExample)
JP (1) JP6750140B2 (enExample)
CN (1) CN107110865B (enExample)
ES (1) ES2813829T3 (enExample)
WO (1) WO2016029117A1 (enExample)

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WO2020091408A1 (ko) * 2018-10-30 2020-05-07 주식회사 애니벳 반려동물에서 종양질병의 보조적 진단을 위한 바이오마커 검사방법
KR102407703B1 (ko) * 2018-10-30 2022-06-22 바디텍메드(주) 반려동물의 종양 질병을 보조적으로 진단하는 바이오마커 검사방법
CN109557311B (zh) * 2018-12-13 2022-02-15 中南大学湘雅医院 结直肠癌诊断标志物及结直肠癌的检测产品及其应用
WO2021024009A1 (en) * 2019-08-02 2021-02-11 Shanghai Yunxiang Medical Technology Co., Ltd. Methods and compositions for providing colon cancer assessment using protein biomarkers
JP7741067B2 (ja) * 2019-10-18 2025-09-17 エグザクト サイエンシーズ コーポレーション 複数の分析物を用いた糞便抗原検査
CN113018416B (zh) * 2021-03-09 2022-09-20 复旦大学附属中山医院 天冬酰胺内肽酶抑制剂的制药用途
CN118197643B (zh) * 2024-04-03 2025-01-07 南通大学附属医院 基于肠道环境数据的肠道肿瘤检测系统

Family Cites Families (18)

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Publication number Priority date Publication date Assignee Title
US20060154245A1 (en) * 1999-04-09 2006-07-13 Rigshospitalet Method for detecting, screening and/or montoring a cancer in individual
JP2004198419A (ja) * 2002-12-13 2004-07-15 Bayer Healthcare Llc Timp1を用いた検出方法
EP1761781A1 (en) * 2004-06-18 2007-03-14 Roche Diagnostics GmbH Use of protein rs15a as a marker for colorectal cancer
JP4916441B2 (ja) * 2004-08-13 2012-04-11 インディヴュームド ゲゼルシャフト ミット ベシュレンクテル ハフツング 結腸直腸腺腫及び/又は癌腫に対するバイオマーカーとしてのトランスサイレチンの使用;検出方法及び試験システム
EP1831695B1 (en) * 2004-12-23 2009-05-06 F. Hoffmann-La Roche AG Use of cyfra 21-1 and osteopontin as markers for colorectal cancer
CN101238373A (zh) * 2005-08-19 2008-08-06 因迪维姆德有限公司 内质蛋白片段及其衍生物作为结肠直肠腺瘤和/或癌的生物标记的用途;用于检测的方法和测试系统
CN101346628A (zh) * 2005-12-22 2009-01-14 霍夫曼-拉罗奇有限公司 包含骨桥蛋白和癌胚抗原的标记物组合在结肠直肠癌的评估中的用途
EP2071337A1 (en) * 2007-12-10 2009-06-17 F.Hoffmann-La Roche Ag Seprase as a marker for cancer
WO2009074276A2 (en) * 2007-12-10 2009-06-18 Roche Diagnostics Gmbh Marker panel for colorectal cancer
JP5172020B2 (ja) * 2008-11-12 2013-03-27 エフ.ホフマン−ラ ロシュ アーゲー 癌のマーカーとしてのpacap
US10815517B2 (en) * 2009-04-28 2020-10-27 Roche Diagnostics Operations, Inc. Use of DPPIV/seprase as a marker for cancer
JP5312684B2 (ja) * 2009-05-04 2013-10-09 エフ.ホフマン−ラ ロシュ アーゲー 癌のマーカーとしてのdppiv/セプラーゼの使用
BR112012025593A2 (pt) * 2010-04-06 2019-06-25 Caris Life Sciences Luxembourg Holdings biomarcadores em circulação para doença
CN103080334B (zh) * 2010-06-04 2016-05-04 复旦大学 用于诊断早期结直肠癌及高级腺瘤的微rna生物标记及方法
WO2011158667A1 (ja) * 2010-06-16 2011-12-22 国立大学法人浜松医科大学 大腸腫瘍の検出方法
EP2678448A4 (en) * 2011-02-22 2014-10-01 Caris Life Sciences Luxembourg Holdings S A R L CIRCULATING BIOMARKERS
JP5805518B2 (ja) * 2011-12-21 2015-11-04 株式会社島津製作所 マルチプレックス大腸がんマーカーパネル
KR101461615B1 (ko) * 2012-01-03 2015-04-22 국립암센터 암 진단 장치

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ES2813829T3 (es) 2021-03-25
JP2017532577A (ja) 2017-11-02
EP3183578A1 (en) 2017-06-28
CN107110865B (zh) 2020-01-10
CN107110865A (zh) 2017-08-29
EP3183578B8 (en) 2020-07-15
US20160178631A1 (en) 2016-06-23
EP3183578B1 (en) 2020-06-03
WO2016029117A1 (en) 2016-02-25

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