JP6747981B2 - 腫瘍抗原発現組換えポックスウイルス及び免疫チェックポイント分子アンタゴニストまたはアゴニストを用いた癌治療のための併用療法 - Google Patents

腫瘍抗原発現組換えポックスウイルス及び免疫チェックポイント分子アンタゴニストまたはアゴニストを用いた癌治療のための併用療法 Download PDF

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JP6747981B2
JP6747981B2 JP2016567370A JP2016567370A JP6747981B2 JP 6747981 B2 JP6747981 B2 JP 6747981B2 JP 2016567370 A JP2016567370 A JP 2016567370A JP 2016567370 A JP2016567370 A JP 2016567370A JP 6747981 B2 JP6747981 B2 JP 6747981B2
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cancer
immune checkpoint
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agonist
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フォイ・スーザン
マンドル・ステファニー
ラウントリー・リャン
フランツソフ・アレックス
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バヴァリアン・ノルディック・アクティーゼルスカブ
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JP2016567370A 2014-05-13 2015-05-08 腫瘍抗原発現組換えポックスウイルス及び免疫チェックポイント分子アンタゴニストまたはアゴニストを用いた癌治療のための併用療法 Active JP6747981B2 (ja)

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Application Number Priority Date Filing Date Title
US201461992788P 2014-05-13 2014-05-13
US61/992,788 2014-05-13
PCT/US2015/029855 WO2015175334A2 (en) 2014-05-13 2015-05-08 Combination therapy for treating cancer with a recombinant poxvirus expressing a tumor antigen and an immune checkpoint molecule antagonist or agonist

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JP2017515837A JP2017515837A (ja) 2017-06-15
JP2017515837A5 JP2017515837A5 (https=) 2018-06-14
JP6747981B2 true JP6747981B2 (ja) 2020-08-26

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US (1) US20170266270A1 (https=)
EP (1) EP3142690B1 (https=)
JP (1) JP6747981B2 (https=)
KR (1) KR102499737B1 (https=)
CN (1) CN106456747A (https=)
AU (1) AU2015259510B2 (https=)
CA (1) CA2946418C (https=)
DK (1) DK3142690T3 (https=)
ES (1) ES2913236T3 (https=)
IL (1) IL248507B (https=)
NZ (1) NZ725459A (https=)
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WO (1) WO2015175334A2 (https=)

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CN114591433A (zh) 2015-07-13 2022-06-07 西托姆克斯治疗公司 抗pd-1抗体、可活化抗pd-1抗体及其使用方法
JP7025339B2 (ja) 2016-02-25 2022-02-24 メモリアル スローン ケタリング キャンサー センター 癌免疫療法のための、チミジンキナーゼの欠失を伴い、ヒトｆｌｔ３ｌまたはｇｍ－ｃｓｆの発現を伴うかまたは伴わない、複製可能な弱毒化ワクシニアウイルス
CN109152827B (zh) 2016-02-25 2023-07-21 纪念斯隆凯特琳癌症中心 重组mva或表达人flt3l的mvaδe3l及其作为抗固体肿瘤的免疫治疗剂的用途
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KR102754876B1 (ko) * 2017-08-24 2025-01-13 버베리안 노딕 에이/에스 재조합 mva 및 항체의 정맥내 투여에 의한 암 치료를 위한 병용 요법
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WO2019152922A1 (en) * 2018-02-05 2019-08-08 Nant Holdings Ip, Llc Calreticulin and fusion proteins
TWI905535B (zh) * 2018-04-23 2025-11-21 美商南特細胞公司 新抗原表位疫苗及免疫刺激組合物及方法
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TWI852977B (zh) 2019-01-10 2024-08-21 美商健生生物科技公司 前列腺新抗原及其用途
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KR20220115569A (ko) 2019-11-18 2022-08-17 얀센 바이오테크 인코포레이티드 돌연변이 calr 및 jak2에 기반한 백신 및 이의 용도
CN114929268A (zh) * 2019-11-20 2022-08-19 巴法里安诺迪克有限公司 4-1bbl辅助的重组修饰的安卡拉痘苗病毒(mva)的医疗用途
CN114867491B (zh) * 2019-11-20 2025-08-15 巴法里安诺迪克有限公司 用于肿瘤内和/或静脉内施用以治疗癌症的重组mva病毒
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EP3142690B1 (en) 2022-02-23
NZ725459A (en) 2023-04-28
RU2016148311A (ru) 2018-06-18
WO2015175334A3 (en) 2016-02-04
RU2016148311A3 (https=) 2018-12-26
JP2017515837A (ja) 2017-06-15
IL248507A0 (en) 2016-12-29
AU2015259510A1 (en) 2016-11-10
CA2946418C (en) 2023-07-04
WO2015175334A2 (en) 2015-11-19
CN106456747A (zh) 2017-02-22
ES2913236T3 (es) 2022-06-01
EP3142690A2 (en) 2017-03-22
DK3142690T3 (da) 2022-05-09
AU2015259510B2 (en) 2020-10-01
IL248507B (en) 2022-07-01
RU2724433C2 (ru) 2020-06-23
KR20170003556A (ko) 2017-01-09
US20170266270A1 (en) 2017-09-21
KR102499737B1 (ko) 2023-02-13
CA2946418A1 (en) 2015-11-19

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