JP6655061B2 - 状態を治療するためのｉｌ−１５およびｉｌ−１５ｒアルファヘテロ二量体用量増加レジメン - Google Patents

状態を治療するためのｉｌ−１５およびｉｌ−１５ｒアルファヘテロ二量体用量増加レジメン Download PDF

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JP6655061B2
JP6655061B2 JP2017504713A JP2017504713A JP6655061B2 JP 6655061 B2 JP6655061 B2 JP 6655061B2 JP 2017504713 A JP2017504713 A JP 2017504713A JP 2017504713 A JP2017504713 A JP 2017504713A JP 6655061 B2 JP6655061 B2 JP 6655061B2
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JP2017523187A (ja
JP2017523187A5 (enExample
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フェルバー，バーバラ，ケー．
フィンキールステイン，セルジョ
パヴラキス，ジョージ，エヌ．
バーナキス，ジョン，エヌ．
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    • A—HUMAN NECESSITIES
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    • A61K38/00—Medicinal preparations containing peptides
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    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/20—Interleukins [IL]
    • A61K38/2046—IL-7
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
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    • A—HUMAN NECESSITIES
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    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P37/02—Immunomodulators
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
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    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00—Reverse transcribing RNA viruses
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  • Health & Medical Sciences (AREA)
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  • General Chemical & Material Sciences (AREA)
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  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
JP2017504713A 2014-07-29 2015-07-28 状態を治療するためのｉｌ−１５およびｉｌ−１５ｒアルファヘテロ二量体用量増加レジメン Active JP6655061B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201462030394P 2014-07-29 2014-07-29
US62/030,394 2014-07-29
PCT/US2015/042489 WO2016018920A1 (en) 2014-07-29 2015-07-28 Il-15 and il-15ralpha heterodimer dose escalation regimens for treating conditions

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JP2017523187A JP2017523187A (ja) 2017-08-17
JP2017523187A5 JP2017523187A5 (enExample) 2018-08-30
JP6655061B2 true JP6655061B2 (ja) 2020-02-26

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US (1) US10335460B2 (enExample)
EP (1) EP3174974B1 (enExample)
JP (1) JP6655061B2 (enExample)
ES (1) ES2811974T3 (enExample)
WO (1) WO2016018920A1 (enExample)

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EP3174974A1 (en) 2017-06-07
EP3174974A4 (en) 2018-04-18
JP2017523187A (ja) 2017-08-17
WO2016018920A1 (en) 2016-02-04
US10335460B2 (en) 2019-07-02
ES2811974T3 (es) 2021-03-15
US20170202924A1 (en) 2017-07-20
EP3174974B1 (en) 2020-05-20
WO2016018920A8 (en) 2017-01-12

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