JP6625045B2 - 相同組換え欠損を評価するための方法および材料 - Google Patents
相同組換え欠損を評価するための方法および材料Info
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- JP6625045B2 JP6625045B2 JP2016506657A JP2016506657A JP6625045B2 JP 6625045 B2 JP6625045 B2 JP 6625045B2 JP 2016506657 A JP2016506657 A JP 2016506657A JP 2016506657 A JP2016506657 A JP 2016506657A JP 6625045 B2 JP6625045 B2 JP 6625045B2
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| WO2017165270A1 (en) * | 2016-03-21 | 2017-09-28 | Myriad Genetics, Inc. | Homologous recombination deficiency to predict neoadjuvant chemotherapy necessity in bladder cancer |
| WO2017178509A1 (en) | 2016-04-12 | 2017-10-19 | Xentech | Methods for predicting sensibility to treatment with parp inhibitors in cancerous patients |
| GB2555765A (en) | 2016-05-01 | 2018-05-16 | Genome Res Ltd | Method of detecting a mutational signature in a sample |
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| EP3478286B1 (en) * | 2016-06-29 | 2024-01-03 | Tesaro, Inc. | Methods of treating ovarian cancer |
| EP3802923A4 (en) | 2018-06-11 | 2022-03-16 | Foundation Medicine, Inc. | COMPOSITIONS AND METHODS FOR ASSESSING GENOMIC ALTERATIONS |
| WO2020137076A1 (ja) * | 2018-12-28 | 2020-07-02 | 国立大学法人 東京大学 | Parp阻害剤に対する癌の感受性の予測方法および相同組換修復不全を有する癌の検出方法 |
| JP7368483B2 (ja) | 2019-02-12 | 2023-10-24 | テンパス ラブズ,インコーポレイテッド | 相同組換え欠損を推定するための統合された機械学習フレームワーク |
| ES2989374T3 (es) | 2019-12-10 | 2024-11-26 | Tempus Ai Inc | Sistemas y procedimientos para predecir el estado de deficiencia de recombinación homóloga de una muestra |
| JP2023506084A (ja) * | 2019-12-16 | 2023-02-14 | アジレント・テクノロジーズ・インク | ゲノム瘢痕アッセイ及び関連する方法 |
| EP3945525A1 (en) | 2020-07-27 | 2022-02-02 | Sophia Genetics S.A. | Methods for identifying chromosomal spatial instability such as homologous repair deficiency in low coverage next-generation sequencing data |
| CN111883211B (zh) * | 2020-08-07 | 2021-04-23 | 张哲� | 一种表征hrd同源重组修复缺陷的基因瘢痕及鉴定方法 |
| US11718869B2 (en) * | 2020-08-12 | 2023-08-08 | Zhenyue Biotechnology Jiangsu Co., Ltd. | Method and kit for determining genome instability based on next generation sequencing (NGS) |
| CN112410423B (zh) * | 2020-11-03 | 2021-08-13 | 南京世和基因生物技术股份有限公司 | 同源重组缺失的标志物、检测方法以及检测系统 |
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| JP2019165731A (ja) * | 2013-04-05 | 2019-10-03 | ミリアド・ジェネティックス・インコーポレイテッド | 相同組換え欠損を評価するための方法および材料 |
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| JP7522643B2 (ja) | 2024-07-25 |
| PT2981624T (pt) | 2020-03-23 |
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| AU2022211880A1 (en) | 2022-09-01 |
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