JP6504834B2 - 検査装置 - Google Patents

検査装置 Download PDF

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JP6504834B2
JP6504834B2 JP2015013445A JP2015013445A JP6504834B2 JP 6504834 B2 JP6504834 B2 JP 6504834B2 JP 2015013445 A JP2015013445 A JP 2015013445A JP 2015013445 A JP2015013445 A JP 2015013445A JP 6504834 B2 JP6504834 B2 JP 6504834B2
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bacteria
fungus
culture
determination
image
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JP2016136876A5 (https=
JP2016136876A (ja
Inventor
植松 千宗
千宗 植松
宗郎 前嶋
宗郎 前嶋
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Hitachi High Tech Corp
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Hitachi High Technologies Corp
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Priority to JP2015013445A priority Critical patent/JP6504834B2/ja
Application filed by Hitachi High Technologies Corp filed Critical Hitachi High Technologies Corp
Priority to PCT/JP2016/051770 priority patent/WO2016121627A1/ja
Priority to EP16743230.1A priority patent/EP3252138B1/en
Priority to EP21197801.0A priority patent/EP3967744A1/en
Priority to US15/544,302 priority patent/US10793821B2/en
Publication of JP2016136876A publication Critical patent/JP2016136876A/ja
Publication of JP2016136876A5 publication Critical patent/JP2016136876A5/ja
Priority to JP2019058459A priority patent/JP6906005B2/ja
Application granted granted Critical
Publication of JP6504834B2 publication Critical patent/JP6504834B2/ja
Priority to US17/010,467 priority patent/US11851642B2/en
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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/30Means for regulation, monitoring, measurement or control, e.g. flow regulation of concentration
    • C12M41/36Means for regulation, monitoring, measurement or control, e.g. flow regulation of concentration of biomass, e.g. colony counters or by turbidity measurements
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
    • C12Q1/04Determining presence or kind of microorganism; Use of selective media for testing antibiotics or bacteriocides; Compositions containing a chemical indicator therefor
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M1/00Apparatus for enzymology or microbiology
    • C12M1/34Measuring or testing with condition measuring or sensing means, e.g. colony counters
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00Constructional details, e.g. recesses, hinges
    • C12M23/02Form or structure of the vessel
    • C12M23/12Well or multiwell plates
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/46Means for regulation, monitoring, measurement or control, e.g. flow regulation of cellular or enzymatic activity or functionality, e.g. cell viability
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
    • C12Q1/04Determining presence or kind of microorganism; Use of selective media for testing antibiotics or bacteriocides; Compositions containing a chemical indicator therefor
    • C12Q1/06Quantitative determination
    • C12Q1/08Quantitative determination using multifield media
    • GPHYSICS
    • G06COMPUTING OR CALCULATING; COUNTING
    • G06TIMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T1/00General purpose image data processing
    • GPHYSICS
    • G06COMPUTING OR CALCULATING; COUNTING
    • G06TIMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T7/00Image analysis
    • G06T7/0002Inspection of images, e.g. flaw detection
    • G06T7/0012Biomedical image inspection
    • G06T7/0014Biomedical image inspection using an image reference approach
    • G06T7/0016Biomedical image inspection using an image reference approach involving temporal comparison
    • GPHYSICS
    • G02OPTICS
    • G02BOPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00Microscopes
    • G02B21/24Base structure
    • G02B21/26Stages; Adjusting means therefor
    • GPHYSICS
    • G02OPTICS
    • G02BOPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00Microscopes
    • G02B21/36Microscopes arranged for photographic purposes or projection purposes or digital imaging or video purposes including associated control and data processing arrangements
    • G02B21/365Control or image processing arrangements for digital or video microscopes
    • G02B21/367Control or image processing arrangements for digital or video microscopes providing an output produced by processing a plurality of individual source images, e.g. image tiling, montage, composite images, depth sectioning, image comparison
    • GPHYSICS
    • G02OPTICS
    • G02BOPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00Microscopes
    • G02B21/36Microscopes arranged for photographic purposes or projection purposes or digital imaging or video purposes including associated control and data processing arrangements
    • G02B21/368Microscopes arranged for photographic purposes or projection purposes or digital imaging or video purposes including associated control and data processing arrangements details of associated display arrangements, e.g. mounting of LCD monitor
    • GPHYSICS
    • G06COMPUTING OR CALCULATING; COUNTING
    • G06TIMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T2207/00Indexing scheme for image analysis or image enhancement
    • G06T2207/10Image acquisition modality
    • G06T2207/10056Microscopic image

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  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Analytical Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Physics & Mathematics (AREA)
  • Biomedical Technology (AREA)
  • Sustainable Development (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Toxicology (AREA)
  • Biophysics (AREA)
  • Theoretical Computer Science (AREA)
  • General Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Radiology & Medical Imaging (AREA)
  • Clinical Laboratory Science (AREA)
  • Medical Informatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Cell Biology (AREA)
  • Quality & Reliability (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Image Processing (AREA)
  • Image Analysis (AREA)
JP2015013445A 2015-01-27 2015-01-27 検査装置 Active JP6504834B2 (ja)

Priority Applications (7)

Application Number Priority Date Filing Date Title
JP2015013445A JP6504834B2 (ja) 2015-01-27 2015-01-27 検査装置
EP16743230.1A EP3252138B1 (en) 2015-01-27 2016-01-22 Test device
EP21197801.0A EP3967744A1 (en) 2015-01-27 2016-01-22 Test device
US15/544,302 US10793821B2 (en) 2015-01-27 2016-01-22 Test device
PCT/JP2016/051770 WO2016121627A1 (ja) 2015-01-27 2016-01-22 検査装置
JP2019058459A JP6906005B2 (ja) 2015-01-27 2019-03-26 細菌または真菌の同定検査や薬剤感受性検査の判定を行う方法、および検査装置
US17/010,467 US11851642B2 (en) 2015-01-27 2020-09-02 Test device

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2015013445A JP6504834B2 (ja) 2015-01-27 2015-01-27 検査装置

Related Child Applications (1)

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JP2019058459A Division JP6906005B2 (ja) 2015-01-27 2019-03-26 細菌または真菌の同定検査や薬剤感受性検査の判定を行う方法、および検査装置

Publications (3)

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JP2016136876A JP2016136876A (ja) 2016-08-04
JP2016136876A5 JP2016136876A5 (https=) 2017-04-27
JP6504834B2 true JP6504834B2 (ja) 2019-04-24

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JP2015013445A Active JP6504834B2 (ja) 2015-01-27 2015-01-27 検査装置

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US (2) US10793821B2 (https=)
EP (2) EP3967744A1 (https=)
JP (1) JP6504834B2 (https=)
WO (1) WO2016121627A1 (https=)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2020532993A (ja) * 2017-09-07 2020-11-19 コーニング インコーポレイテッド 光学的細胞培養監視及び検体測定システム
JP7032216B2 (ja) * 2018-04-04 2022-03-08 株式会社日立ハイテク 細菌検査装置および細菌検査方法
JP7319407B2 (ja) * 2018-04-04 2023-08-01 株式会社日立ハイテク 細菌検査装置および細菌検査方法
JP7130109B2 (ja) * 2019-03-04 2022-09-02 株式会社日立ハイテク 検査装置および検査方法
CN112400023A (zh) * 2019-03-14 2021-02-23 株式会社日立高新技术 药剂敏感性检查方法
EP3996583B1 (en) * 2019-07-08 2026-02-25 Emory University Method and system for determining antimicrobial resistance of a sample using surface topography determined from optical imaging data
WO2021067170A1 (en) * 2019-10-01 2021-04-08 Beth Israel Deaconess Medical Center, Inc. Rapid antimicrobial susceptibility testing by image analysis

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5698414A (en) * 1989-10-24 1997-12-16 Infectech, Inc. Method and apparatus for testing paraffinophilic microorganisms for antimicrobial agent sensitivity
JP3045566B2 (ja) * 1991-05-22 2000-05-29 和光純薬工業株式会社 細菌検査装置
IL101522A (en) 1992-04-08 1997-09-30 Combact Imaging Systems Ltd Detection of microorganisms in a sample and determination of the sensitivity of microorganisms to antibiotics
JPH09117299A (ja) * 1995-10-25 1997-05-06 Shimadzu Corp 細菌の抗生物質感受性検査方法
US6420622B1 (en) 1997-08-01 2002-07-16 3M Innovative Properties Company Medical article having fluid control film
JP4217378B2 (ja) * 1997-08-01 2009-01-28 スリーエム カンパニー 微生物の検知および計数の方法および器具
US6251624B1 (en) * 1999-03-12 2001-06-26 Akzo Nobel N.V. Apparatus and method for detecting, quantifying and characterizing microorganisms
WO2000067037A2 (en) 1999-04-29 2000-11-09 Dade Microscan Inc. A combined rapid anti-microbial susceptibility assay and microorganism identification system
GB2372147A (en) 2001-02-13 2002-08-14 Marconi Applied Techn Ltd Magnetron with radiation absorbing dielectric resonator
US6645737B2 (en) 2001-04-24 2003-11-11 Dade Microscan Inc. Method for maintaining test accuracy within a microbiological test array
US20120077206A1 (en) * 2003-07-12 2012-03-29 Accelr8 Technology Corporation Rapid Microbial Detection and Antimicrobial Susceptibility Testing
JP2005261260A (ja) * 2004-03-17 2005-09-29 Fuji Electric Holdings Co Ltd 微生物または細胞の検査装置及び検査方法
JP4839010B2 (ja) * 2005-03-29 2011-12-14 シスメックス株式会社 分析システム、データ処理装置、及びアプリケーションプログラム
JP4821279B2 (ja) * 2005-11-11 2011-11-24 株式会社ニコン 培養装置
PL217886B1 (pl) 2009-03-13 2014-08-29 Int Tobacco Machinery Poland Układ transferujący, współpracujący z maszyną do produkcji sztabek produktów tytoniowych i filtrowych, oraz sposób transferu takich sztabek w układzie transferującym
JP2010213598A (ja) * 2009-03-16 2010-09-30 Kyokuto Seiyaku Kogyo Kk 抗菌薬の微生物に対する有効性の検査方法
JP2013538567A (ja) * 2010-08-12 2013-10-17 ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア 抗菌化合物を同定するおよび抗生物質感受性を決定する方法
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JP6619544B2 (ja) 2014-03-19 2019-12-11 株式会社日立ハイテクノロジーズ 検査装置

Also Published As

Publication number Publication date
US11851642B2 (en) 2023-12-26
EP3252138A1 (en) 2017-12-06
EP3252138B1 (en) 2021-10-27
US10793821B2 (en) 2020-10-06
US20180010084A1 (en) 2018-01-11
EP3967744A1 (en) 2022-03-16
US20200399581A1 (en) 2020-12-24
JP2016136876A (ja) 2016-08-04
WO2016121627A1 (ja) 2016-08-04
EP3252138A4 (en) 2018-08-08

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