JP6504834B2 - 検査装置 - Google Patents

検査装置 Download PDF

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Publication number
JP6504834B2
JP6504834B2 JP2015013445A JP2015013445A JP6504834B2 JP 6504834 B2 JP6504834 B2 JP 6504834B2 JP 2015013445 A JP2015013445 A JP 2015013445A JP 2015013445 A JP2015013445 A JP 2015013445A JP 6504834 B2 JP6504834 B2 JP 6504834B2
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bacteria
fungus
culture
determination
image
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Japanese (ja)
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JP2016136876A (ja
JP2016136876A5 (enExample
Inventor
植松　千宗
千宗 植松
宗郎 前嶋
宗郎 前嶋
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Hitachi High-Tech Corp
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Hitachi High Technologies Corp
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Priority to JP2015013445A priority Critical patent/JP6504834B2/ja
Application filed by Hitachi High Technologies Corp filed Critical Hitachi High Technologies Corp
Priority to US15/544,302 priority patent/US10793821B2/en
Priority to EP21197801.0A priority patent/EP3967744A1/en
Priority to PCT/JP2016/051770 priority patent/WO2016121627A1/ja
Priority to EP16743230.1A priority patent/EP3252138B1/en
Publication of JP2016136876A publication Critical patent/JP2016136876A/ja
Publication of JP2016136876A5 publication Critical patent/JP2016136876A5/ja
Priority to JP2019058459A priority patent/JP6906005B2/ja
Application granted granted Critical
Publication of JP6504834B2 publication Critical patent/JP6504834B2/ja
Priority to US17/010,467 priority patent/US11851642B2/en
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/30—Means for regulation, monitoring, measurement or control, e.g. flow regulation of concentration
    • C12M41/36—Means for regulation, monitoring, measurement or control, e.g. flow regulation of concentration of biomass, e.g. colony counters or by turbidity measurements
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
    • C12Q1/04—Determining presence or kind of microorganism; Use of selective media for testing antibiotics or bacteriocides; Compositions containing a chemical indicator therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M1/00—Apparatus for enzymology or microbiology
    • C12M1/34—Measuring or testing with condition measuring or sensing means, e.g. colony counters
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00—Constructional details, e.g. recesses, hinges
    • C12M23/02—Form or structure of the vessel
    • C12M23/12—Well or multiwell plates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/46—Means for regulation, monitoring, measurement or control, e.g. flow regulation of cellular or enzymatic activity or functionality, e.g. cell viability
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
    • C12Q1/04—Determining presence or kind of microorganism; Use of selective media for testing antibiotics or bacteriocides; Compositions containing a chemical indicator therefor
    • C12Q1/06—Quantitative determination
    • C12Q1/08—Quantitative determination using multifield media
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T1/00—General purpose image data processing
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T7/00—Image analysis
    • G06T7/0002—Inspection of images, e.g. flaw detection
    • G06T7/0012—Biomedical image inspection
    • G06T7/0014—Biomedical image inspection using an image reference approach
    • G06T7/0016—Biomedical image inspection using an image reference approach involving temporal comparison
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/24—Base structure
    • G02B21/26—Stages; Adjusting means therefor
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/36—Microscopes arranged for photographic purposes or projection purposes or digital imaging or video purposes including associated control and data processing arrangements
    • G02B21/365—Control or image processing arrangements for digital or video microscopes
    • G02B21/367—Control or image processing arrangements for digital or video microscopes providing an output produced by processing a plurality of individual source images, e.g. image tiling, montage, composite images, depth sectioning, image comparison
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/36—Microscopes arranged for photographic purposes or projection purposes or digital imaging or video purposes including associated control and data processing arrangements
    • G02B21/368—Microscopes arranged for photographic purposes or projection purposes or digital imaging or video purposes including associated control and data processing arrangements details of associated display arrangements, e.g. mounting of LCD monitor
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T2207/00—Indexing scheme for image analysis or image enhancement
    • G06T2207/10—Image acquisition modality
    • G06T2207/10056—Microscopic image

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  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Physics & Mathematics (AREA)
  • Biomedical Technology (AREA)
  • Sustainable Development (AREA)
  • Biophysics (AREA)
  • Toxicology (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • General Physics & Mathematics (AREA)
  • Theoretical Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Medical Informatics (AREA)
  • Radiology & Medical Imaging (AREA)
  • Clinical Laboratory Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Quality & Reliability (AREA)
  • Cell Biology (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Image Processing (AREA)
  • Image Analysis (AREA)
JP2015013445A 2015-01-27 2015-01-27 検査装置 Active JP6504834B2 (ja)

Priority Applications (7)

Application Number Priority Date Filing Date Title
JP2015013445A JP6504834B2 (ja) 2015-01-27 2015-01-27 検査装置
EP21197801.0A EP3967744A1 (en) 2015-01-27 2016-01-22 Test device
PCT/JP2016/051770 WO2016121627A1 (ja) 2015-01-27 2016-01-22 検査装置
EP16743230.1A EP3252138B1 (en) 2015-01-27 2016-01-22 Test device
US15/544,302 US10793821B2 (en) 2015-01-27 2016-01-22 Test device
JP2019058459A JP6906005B2 (ja) 2015-01-27 2019-03-26 細菌または真菌の同定検査や薬剤感受性検査の判定を行う方法、および検査装置
US17/010,467 US11851642B2 (en) 2015-01-27 2020-09-02 Test device

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2015013445A JP6504834B2 (ja) 2015-01-27 2015-01-27 検査装置

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2019058459A Division JP6906005B2 (ja) 2015-01-27 2019-03-26 細菌または真菌の同定検査や薬剤感受性検査の判定を行う方法、および検査装置

Publications (3)

Publication Number Publication Date
JP2016136876A JP2016136876A (ja) 2016-08-04
JP2016136876A5 JP2016136876A5 (enExample) 2017-04-27
JP6504834B2 true JP6504834B2 (ja) 2019-04-24

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JP2015013445A Active JP6504834B2 (ja) 2015-01-27 2015-01-27 検査装置

Country Status (4)

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US (2) US10793821B2 (enExample)
EP (2) EP3967744A1 (enExample)
JP (1) JP6504834B2 (enExample)
WO (1) WO2016121627A1 (enExample)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11834696B2 (en) * 2017-04-05 2023-12-05 Arizona Board Of Regents On Behalf Of Arizona State University Antimicrobial susceptibility testing with large-volume light scattering imaging and deep learning video microscopy
JP2020532993A (ja) * 2017-09-07 2020-11-19 コーニング インコーポレイテッド 光学的細胞培養監視及び検体測定システム
JP7032216B2 (ja) 2018-04-04 2022-03-08 株式会社日立ハイテク 細菌検査装置および細菌検査方法
JP7319407B2 (ja) * 2018-04-04 2023-08-01 株式会社日立ハイテク 細菌検査装置および細菌検査方法
EP3936602B1 (en) * 2019-03-04 2025-02-12 Hitachi High-Tech Corporation Testing apparatus and testing method
US12698519B2 (en) 2019-03-14 2026-08-04 Hitachi High-Tech Corporation Chemical susceptibility inspection method
US20220282299A1 (en) * 2019-07-08 2022-09-08 Emory University Systems and Methods for Determining Antimicrobial Resistance of a Sample Using Surface Topography Determined from Optical Imaging Data
EP4038196A4 (en) * 2019-10-01 2024-01-24 Beth Israel Deaconess Medical Center, Inc. RAPID ANTIMICROBIAL SUSCEPTIBILITY TESTING BY IMAGE ANALYSIS

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5698414A (en) * 1989-10-24 1997-12-16 Infectech, Inc. Method and apparatus for testing paraffinophilic microorganisms for antimicrobial agent sensitivity
JP3045566B2 (ja) * 1991-05-22 2000-05-29 和光純薬工業株式会社 細菌検査装置
IL101522A (en) 1992-04-08 1997-09-30 Combact Imaging Systems Ltd Detection of microorganisms in a sample and determination of the sensitivity of microorganisms to antibiotics
JPH09117299A (ja) * 1995-10-25 1997-05-06 Shimadzu Corp 細菌の抗生物質感受性検査方法
US6420622B1 (en) 1997-08-01 2002-07-16 3M Innovative Properties Company Medical article having fluid control film
BRPI9810844B1 (pt) * 1997-08-01 2016-04-05 Minnesota Mining & Mfg dispositivo de ensaio para detectar microorganismos em uma amostra líquida, e, processo para conduzir um número de análises mais provável
US6251624B1 (en) * 1999-03-12 2001-06-26 Akzo Nobel N.V. Apparatus and method for detecting, quantifying and characterizing microorganisms
WO2000067037A2 (en) * 1999-04-29 2000-11-09 Dade Microscan Inc. A combined rapid anti-microbial susceptibility assay and microorganism identification system
GB2372147A (en) 2001-02-13 2002-08-14 Marconi Applied Techn Ltd Magnetron with radiation absorbing dielectric resonator
US6645737B2 (en) 2001-04-24 2003-11-11 Dade Microscan Inc. Method for maintaining test accuracy within a microbiological test array
US20120077206A1 (en) * 2003-07-12 2012-03-29 Accelr8 Technology Corporation Rapid Microbial Detection and Antimicrobial Susceptibility Testing
JP2005261260A (ja) * 2004-03-17 2005-09-29 Fuji Electric Holdings Co Ltd 微生物または細胞の検査装置及び検査方法
JP4839010B2 (ja) * 2005-03-29 2011-12-14 シスメックス株式会社 分析システム、データ処理装置、及びアプリケーションプログラム
JP4821279B2 (ja) * 2005-11-11 2011-11-24 株式会社ニコン 培養装置
PL217886B1 (pl) 2009-03-13 2014-08-29 Int Tobacco Machinery Poland Układ transferujący, współpracujący z maszyną do produkcji sztabek produktów tytoniowych i filtrowych, oraz sposób transferu takich sztabek w układzie transferującym
JP2010213598A (ja) * 2009-03-16 2010-09-30 Kyokuto Seiyaku Kogyo Kk 抗菌薬の微生物に対する有効性の検査方法
WO2012021802A2 (en) * 2010-08-12 2012-02-16 The Regents Of The University Of California Method for identifying antimicrobial compounds and determining antibiotic sensitivity
US9399788B2 (en) 2011-09-13 2016-07-26 Osaka University Method for inspecting susceptibility of bacteria or fungi to antimicrobial drug and system for use in the same
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JP6619544B2 (ja) 2014-03-19 2019-12-11 株式会社日立ハイテクノロジーズ 検査装置

Also Published As

Publication number Publication date
WO2016121627A1 (ja) 2016-08-04
JP2016136876A (ja) 2016-08-04
EP3252138A1 (en) 2017-12-06
EP3252138A4 (en) 2018-08-08
EP3967744A1 (en) 2022-03-16
EP3252138B1 (en) 2021-10-27
US20200399581A1 (en) 2020-12-24
US20180010084A1 (en) 2018-01-11
US10793821B2 (en) 2020-10-06
US11851642B2 (en) 2023-12-26

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